GO:0035717

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Name chemokine (C-C motif) ligand 7 binding
Categary Function
Go Slim No
Go Link GO:0035717
Unique Molecular Interactions 50
Total Molecular Interactions 82
Total Single Events 626
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chemokine (C-C motif) ligand 7 binding. They are ordered first by their pain relevance and then by number of times they were reported for chemokine (C-C motif) ligand 7 binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
2 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
3 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
4 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
5 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4
6 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04
7 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98
8 INT209035 Il2 Positive_regulation of Ccr1 1 0.00 0.38 0.73
9 INT209038 Il4 Positive_regulation of Ccr1 1 0.01 0.38 0.73
10 INT209065 Il3 Positive_regulation of Ccr1 1 0.00 0.38 0.73
11 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
12 INT209041 Il10 Positive_regulation of Ccr1 1 0.01 0.37 0.72
13 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72
14 INT222211 TFAM Positive_regulation of Ccr1 1 0.02 1.89 0.68
15 INT297307 Negative_regulation of Binding of Ccr1 and Ccl3 1 0.27 0.73 0.67
16 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67
17 INT281130 Ccl2 Regulation of Gene_expression of Ccr2 1 0.04 1.09 0.64
18 INT281134 Ccl2 Positive_regulation of Gene_expression of Ccr2 1 0.08 1.09 0.64
19 INT281122 Ccl2 Regulation of Ccr2 1 0.04 1.09 0.63
20 INT97635 ABCF1 Positive_regulation of Localization of CCR1 1 0.05 0.51 0.55
21 INT222252 Positive_regulation of Binding of Ccr2 and Fig4 1 0.16 0.67 0.55
22 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55
23 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55
24 INT222245 Binding of Ccr2 and Fig4 1 0.12 0.67 0.55
25 INT281126 Binding of Ccr2 and Cxcr4 1 0.30 0.32 0.44
26 INT181448 Eae1 Positive_regulation of Gene_expression of Ccr2 1 0.04 4.98 0.42
27 INT181081 Binding of Ccr1 and Darc 1 0.01 1.08 0.39
28 INT163909 CCL2 Positive_regulation of Positive_regulation of Ccr2 1 0.05 0.19 0.36
29 INT163908 CCL2 Positive_regulation of Ccr2 1 0.05 0.2 0.35
30 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32
31 INT244233 Ccr1 Positive_regulation of Cxcr1 1 0.16 0.08 0.32
32 INT306107 Binding of CCL2 and Ccr2 1 0.06 0 0.28
33 INT268766 Tlr4 Positive_regulation of Gene_expression of Ccr1 1 0.04 0.4 0.26
34 INT268768 Mip Regulation of Positive_regulation of Ccr1 1 0.44 0.83 0.23
35 INT170993 IL10 Positive_regulation of Gene_expression of CCR1 1 0.12 0.34 0.22
36 INT158209 Binding of CCR1 and AHSA1 1 0.17 0.3 0.2
37 INT158225 Binding of CCR1 and MAPK1 1 0.18 0.3 0.2
38 INT158231 TNFSF14 Positive_regulation of CCR1 1 0.07 0.3 0.2
39 INT158210 Binding of CCR1 and TNFSF14 1 0.05 0.3 0.2
40 INT158212 Negative_regulation of Binding of CCR1 and AHSA1 1 0.20 0.3 0.2
41 INT158200 Positive_regulation of Binding of CCR1 and AHSA1 1 0.23 0.3 0.2
42 INT158201 Positive_regulation of Binding of CCR1 and TNFSF14 1 0.07 0.3 0.2
43 INT158221 Positive_regulation of Binding of CCR1 and MAPK1 1 0.25 0.3 0.2
44 INT158230 Negative_regulation of Binding of CCR1 and TNFSF14 1 0.06 0.3 0.2
45 INT158219 Negative_regulation of Binding of CCR1 and MAPK1 1 0.21 0.3 0.2
46 INT181440 Binding of Ccr2 and Eae1 1 0.03 1.3 0.19
47 INT23585 Binding of KRIT1 and CCR1 1 0.40 0.97 0.19
48 INT172250 Binding of APLNR and CCR1 1 0.12 0 0.17
49 INT352416 Ccl2 Positive_regulation of Ccr2 1 0.23 0.26 0.14
50 INT268765 Tlr4 Positive_regulation of Positive_regulation of Ccr1 1 0.04 0.27 0.13

Single Events

The table below shows the top 100 pain related interactions that have been reported for chemokine (C-C motif) ligand 7 binding. They are ordered first by their pain relevance and then by number of times they were reported in chemokine (C-C motif) ligand 7 binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07
2 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14
3 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81
4 INT151434 Positive_regulation of Ccr2 26 0.68 18.34 16.34
5 INT161222 Positive_regulation of Ccr2 13 0.55 13.77 8.89
6 INT88047 Positive_regulation of Gene_expression of Ccr2 15 0.60 10.5 8.63
7 INT166881 Positive_regulation of Ccr1 31 0.69 18.14 7.9
8 INT102548 Negative_regulation of Ccr2 14 0.59 19.84 7.22
9 INT93144 Gene_expression of CCR1 18 0.75 14.69 6.84
10 INT141611 Positive_regulation of Gene_expression of Ccr1 25 0.69 20.32 6.42
11 INT181022 Binding of Ccr1 15 0.37 10.69 5.37
12 INT150237 Localization of Ccr1 10 0.75 9.25 4.72
13 INT161221 Positive_regulation of Positive_regulation of Ccr2 3 0.50 4.55 3.98
14 INT65700 Localization of CCR1 7 0.51 4 3.91
15 INT222241 Binding of Ccr2 5 0.42 4.09 3.71
16 INT281144 Regulation of Gene_expression of Ccr2 2 0.44 2.38 3.29
17 INT222237 Negative_regulation of Gene_expression of Ccr2 3 0.37 3.39 2.91
18 INT151436 Regulation of Ccr2 4 0.44 2.81 2.82
19 INT222226 Negative_regulation of Ccr2 6 0.57 3.69 2.66
20 INT23588 Positive_regulation of CCR1 6 0.67 4.44 2.24
21 INT146504 Regulation of Ccr2 5 0.39 3.58 2.21
22 INT181402 Negative_regulation of Ccr1 8 0.42 7 2.2
23 INT112970 Regulation of Ccr1 8 0.29 7.77 1.93
24 INT181341 Binding of Ccr2 8 0.32 6.47 1.77
25 INT102550 Positive_regulation of Gene_expression of Ccr2 6 0.69 4.53 1.67
26 INT181373 Negative_regulation of Gene_expression of Ccr2 5 0.59 5.92 1.44
27 INT281139 Phosphorylation of Ccr2 2 0.79 1.2 1.18
28 INT281141 Positive_regulation of Phosphorylation of Ccr2 2 0.49 1.2 1.18
29 INT268754 Negative_regulation of Gene_expression of Ccr1 5 0.43 2.76 1.13
30 INT222235 Localization of Ccr2 7 0.73 5.32 1.12
31 INT151435 Negative_regulation of Positive_regulation of Ccr2 1 0.53 0.7 1.08
32 INT268753 Negative_regulation of Positive_regulation of Ccr1 1 0.42 2.59 0.96
33 INT161223 Negative_regulation of Positive_regulation of Ccr2 1 0.43 0.83 0.81
34 INT181359 Transcription of Ccr1 4 0.53 1.66 0.8
35 INT268746 Positive_regulation of Binding of Ccr1 1 0.50 1.81 0.79
36 INT222239 Transcription of Ccr2 2 0.61 1.15 0.73
37 INT189481 Regulation of Gene_expression of Ccr1 3 0.45 1.97 0.58
38 INT172297 Binding of CCR1 1 0.36 0.08 0.56
39 INT97637 Positive_regulation of Localization of CCR1 1 0.08 0.51 0.55
40 INT222242 Positive_regulation of Transcription of Ccr2 1 0.44 0.66 0.52
41 INT236350 Transcription of Ccr2 2 0.72 3.59 0.49
42 INT182225 Transcription of CCR1 1 0.57 0.45 0.47
43 INT272877 Localization of Ccr2 2 0.75 1.68 0.46
44 INT281147 Regulation of Binding of Ccr2 1 0.39 0.86 0.46
45 INT268761 Positive_regulation of Positive_regulation of Ccr1 1 0.43 1.51 0.39
46 INT163905 Positive_regulation of Positive_regulation of Ccr2 1 0.13 0.16 0.37
47 INT171023 Negative_regulation of Gene_expression of CCR1 2 0.37 1.53 0.36
48 INT340642 Regulation of Gene_expression of Ccr2 1 0.62 2.26 0.35
49 INT171025 Negative_regulation of Localization of CCR1 1 0.37 0.4 0.25
50 INT268747 Positive_regulation of Localization of Ccr1 1 0.43 0.8 0.23
51 INT268750 Positive_regulation of Transcription of Ccr1 2 0.46 0.26 0.21
52 INT23591 Regulation of CCR1 1 0.26 0.96 0.19
53 INT268764 Regulation of Positive_regulation of Ccr1 1 0.45 0.83 0.18
54 INT181340 Negative_regulation of Negative_regulation of Ccr1 1 0.28 0.67 0.18
55 INT158243 Positive_regulation of Positive_regulation of CCR1 1 0.39 0.26 0.17
56 INT158248 Negative_regulation of Positive_regulation of CCR1 1 0.36 0.26 0.17
57 INT285555 Positive_regulation of Gene_expression of CCR1 1 0.16 1.11 0.1
58 INT236358 Regulation of Transcription of Ccr2 1 0.24 1 0.09
59 INT268757 Phosphorylation of Ccr1 1 0.81 0.08 0.08
60 INT352409 Regulation of Positive_regulation of Ccr2 1 0.44 0.15 0.07
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