GO:0035725

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Name sodium ion transmembrane transport
Categary Process
Go Slim No
Go Link GO:0035725
Unique Molecular Interactions 85
Total Molecular Interactions 105
Total Single Events 1485
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sodium ion transmembrane transport. They are ordered first by their pain relevance and then by number of times they were reported for sodium ion transmembrane transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
2 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
3 INT86090 SCN5A Negative_regulation of Positive_regulation of Abat 1 0.00 0 1.25
4 INT12373 SCN5A Negative_regulation of Cpe 1 0.00 0 0.94
5 INT120820 Binding of ASIC3 and Dlg4 3 0.02 0.11 0.84
6 INT145646 Binding of Scn2a1 and Scn5a 1 0.36 0 0.76
7 INT120819 Binding of ASIC3 and Lin7b 1 0.01 0 0.73
8 INT120818 Lin7b Positive_regulation of ASIC3 1 0.01 0 0.71
9 INT67887 SCN5A Negative_regulation of INA 1 0.02 0.13 0.71
10 INT40180 Regulation of Binding of Oprl1 and Scn7a 1 0.02 0 0.67
11 INT40179 Binding of Oprl1 and Scn7a 1 0.03 0 0.67
12 INT62059 Positive_regulation of SCN5A Positive_regulation of Gene_expression of FOS 1 0.01 0.42 0.66
13 INT111244 Binding of BRS3 and SCN5A 1 0.00 0.72 0.48
14 INT207501 Scn7a Negative_regulation of Gene_expression of ap 1 0.01 0 0.46
15 INT162954 Sema6a Regulation of Scn7a 1 0.10 0.55 0.46
16 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43
17 INT60456 SCN5A Regulation of Scn2a1 1 0.00 0 0.41
18 INT152431 Regulation of Ghrh Positive_regulation of Scn7a 1 0.02 0.17 0.38
19 INT306694 Nav1 Positive_regulation of Gene_expression of Scn7a 1 0.01 0.07 0.38
20 INT152427 Ghrh Positive_regulation of Scn7a 1 0.03 0.17 0.38
21 INT120821 Dlg4 Positive_regulation of ASIC3 1 0.02 0 0.36
22 INT130974 Slc9a3r1 Positive_regulation of ASIC3 1 0.08 0.29 0.36
23 INT207503 Binding of Klkb1 and Scn7a 1 0.02 0 0.3
24 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
25 INT26577 SCN5A Positive_regulation of co 1 0.00 0 0.27
26 INT101371 Inadl Positive_regulation of Gene_expression of ASIC3 1 0.02 0.46 0.27
27 INT279828 Binding of Scn1a and Scn9a 1 0.39 1.64 0.26
28 INT32636 Slc12a3 Regulation of Localization of Nppa 1 0.00 0.41 0.23
29 INT354723 Binding of ASIC3 and Myo18a 1 0.00 0.25 0.23
30 INT339903 Binding of SCN5A and ZGLP1 1 0.01 0.18 0.22
31 INT53902 Atp7b Positive_regulation of Scn7a 1 0.04 0 0.21
32 INT339901 Binding of INS and SCN5A 1 0.01 0.18 0.2
33 INT294904 Binding of Pax3 and Slc12a3 1 0.02 1.9 0.2
34 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
35 INT196303 Binding of SCN5A and ACCS 1 0.00 1.43 0.18
36 INT295433 Binding of PLOD1 and SCN5A 1 0.07 0.25 0.16
37 INT279829 Scn1a Regulation of Gene_expression of Scn9a 1 0.42 1.52 0.15
38 INT317071 KCNC4 Regulation of SCNN1G 1 0.03 0.17 0.13
39 INT354714 Binding of ASIC3 and Gopc 1 0.08 0.1 0.11
40 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1
41 INT186246 Binding of CAT and SCN5A 1 0.03 0.47 0.1
42 INT186242 Binding of ALB and SCN5A 1 0.04 0.36 0.1
43 INT57014 PSMB1 Regulation of SCN5A 1 0.02 0 0.1
44 INT159461 SCN5A Negative_regulation of HPSE 1 0.00 0 0.07
45 INT196624 TNF Negative_regulation of Transcription of SCNN1G 1 0.02 0.07 0.07
46 INT317072 SCNN1G Regulation of NA 1 0.00 0.08 0.04
47 INT196617 TNF Negative_regulation of Gene_expression of SCNN1G 1 0.02 0.08 0.03
48 INT196625 TNF Negative_regulation of Positive_regulation of SCNN1G 1 0.02 0.14 0.03
49 INT186249 Binding of ROS1 and SCN5A 1 0.09 0.73 0.03
50 INT196607 IFNG Regulation of Gene_expression of SCNN1G 1 0.03 0.08 0.03
51 INT187672 Binding of DBT and SCN5A 1 0.00 0.2 0
52 INT311658 Spry1 Regulation of Regulation of Slc12a3 1 0.13 0.81 0
53 INT317075 Binding of NA and SCNN1G 1 0.00 0 0
54 INT311661 Spry1 Regulation of Slc12a3 1 0.30 1.44 0
55 INT317074 CA2 Regulation of SCNN1G 1 0.01 0.08 0
56 INT261883 PKD2 Positive_regulation of Localization of Ca2 1 0.02 0.67 0
57 INT191276 Binding of ABP1 and LSS 1 0.17 0.68 0
58 INT269935 Binding of Smad3 and Scn5a 1 0.13 0 0
59 INT265264 Binding of NA and SCN5A 1 0.03 0.55 0
60 INT265265 SCN5A Regulation of Gene_expression of NAV1 1 0.01 0.16 0
61 INT91242 Binding of SCN5A and PIRT 1 0.00 0 0
62 INT91245 Binding of SCN5A and EMID1 1 0.00 0 0
63 INT269918 Binding of Scn5a and Sox17 1 0.18 0.15 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for sodium ion transmembrane transport. They are ordered first by their pain relevance and then by number of times they were reported in sodium ion transmembrane transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73
2 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88
3 INT81087 Gene_expression of ASIC3 30 0.75 13.62 16.54
4 INT43009 Gene_expression of Scn7a 45 0.68 7.85 10.29
5 INT17028 Positive_regulation of Scn7a 35 0.41 9.83 7.44
6 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3
7 INT17029 Regulation of Scn7a 23 0.45 3.89 7.02
8 INT101008 Gene_expression of Scn5a 5 0.75 26.93 6.06
9 INT23598 Binding of SCN5A 32 0.40 16 5.35
10 INT30209 Localization of SCN5A 24 0.72 7.95 5.35
11 INT77515 Positive_regulation of ASIC3 12 0.67 3.67 4.19
12 INT29832 Negative_regulation of Scn7a 20 0.37 5.91 3.63
13 INT67468 Regulation of SCN5A 27 0.44 4.4 3.47
14 INT101368 Positive_regulation of Gene_expression of ASIC3 6 0.32 2.61 3.06
15 INT113450 Regulation of ASIC3 4 0.21 1.81 2.73
16 INT120814 Negative_regulation of ASIC3 10 0.28 0.99 2.53
17 INT101369 Binding of ASIC3 3 0.32 1.11 2.5
18 INT17559 Localization of Scn7a 13 0.28 4.47 2.37
19 INT157927 Gene_expression of Scn1a 5 0.64 6.55 2.02
20 INT127250 Positive_regulation of Positive_regulation of SCN5A 3 0.38 1.71 1.86
21 INT24358 Binding of Slc12a3 3 0.36 0.35 1.67
22 INT42250 Binding of Scn7a 7 0.33 0.51 1.48
23 INT72249 Negative_regulation of ABP1 6 0.36 1.08 1.41
24 INT72248 Binding of ABP1 7 0.29 4.33 1.36
25 INT143451 Negative_regulation of Gene_expression of Scn5a 2 0.43 4.63 1.34
26 INT52589 Positive_regulation of Gene_expression of SCN5A 14 0.49 3.84 1.33
27 INT196687 Positive_regulation of SCNN1G 6 0.06 3.85 1.32
28 INT92848 Gene_expression of Scn5a 3 0.73 0.23 1.25
29 INT82732 Positive_regulation of Transcription of Scn7a 1 0.17 1.07 1.25
30 INT82726 Transcription of Scn7a 1 0.24 1.05 1.24
31 INT228648 Binding of Scn1a 1 0.27 1.95 1.15
32 INT120696 Gene_expression of SCNN1G 9 0.43 5.46 1.03
33 INT228404 Gene_expression of Slc12a3 6 0.35 7.18 1
34 INT262479 Phosphorylation of Scn7a 2 0.06 1.04 0.96
35 INT120697 Negative_regulation of SCNN1G 6 0.32 3.53 0.92
36 INT207496 Regulation of Gene_expression of Scn7a 8 0.04 1.1 0.89
37 INT143450 Negative_regulation of Scn5a 3 0.43 2.71 0.88
38 INT24359 Negative_regulation of Binding of Slc12a3 1 0.41 0.35 0.88
39 INT33430 Regulation of Localization of Scn7a 1 0.07 0 0.85
40 INT43642 Positive_regulation of Slc12a3 3 0.41 0.7 0.83
41 INT117570 Positive_regulation of Gene_expression of Scn7a 7 0.43 1.4 0.77
42 INT51778 Negative_regulation of Positive_regulation of Scn7a 2 0.26 0.69 0.77
43 INT200438 Negative_regulation of Gene_expression of SCN5A 6 0.36 1.93 0.71
44 INT207494 Positive_regulation of Positive_regulation of Scn7a 1 0.03 0 0.69
45 INT52590 Transcription of SCN5A 4 0.55 0.91 0.65
46 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63
47 INT228394 Localization of Slc12a3 1 0.07 2.72 0.58
48 INT252612 Regulation of Gene_expression of SCN5A 5 0.35 0.56 0.53
49 INT191287 Positive_regulation of ABP1 6 0.39 3.72 0.51
50 INT259832 Positive_regulation of Slc12a3 3 0.23 2.07 0.46
51 INT296806 Positive_regulation of Gene_expression of Scn5a 1 0.50 2.73 0.45
52 INT284882 Positive_regulation of Scn5a 3 0.50 1.73 0.44
53 INT162953 Positive_regulation of Regulation of Scn7a 1 0.16 0.56 0.44
54 INT239952 Regulation of Positive_regulation of Scn7a 1 0.04 0.56 0.43
55 INT130967 Regulation of Localization of ASIC3 1 0.21 0.24 0.42
56 INT130968 Localization of ASIC3 1 0.53 0.24 0.42
57 INT191288 Gene_expression of ABP1 7 0.52 6.61 0.4
58 INT163321 Protein_catabolism of SCN5A 1 0.64 0.25 0.31
59 INT284877 Transcription of Scn5a 3 0.72 1.41 0.3
60 INT259848 Regulation of Slc12a3 2 0.12 2.1 0.3
61 INT137042 Negative_regulation of Transcription of SCN5A 1 0.34 0.23 0.29
62 INT34827 Regulation of ABP1 1 0.62 0.24 0.29
63 INT17560 Positive_regulation of Localization of Scn7a 3 0.08 0.49 0.27
64 INT97025 Positive_regulation of Positive_regulation of ASIC3 1 0.09 0.18 0.27
65 INT92850 Transcription of Scn5a 1 0.52 0.17 0.26
66 INT92849 Positive_regulation of Gene_expression of Scn5a 1 0.49 0.17 0.26
67 INT134515 Gene_expression of Slc12a3 3 0.68 9.57 0.21
68 INT294897 Negative_regulation of Slc12a3 2 0.20 1.77 0.2
69 INT120694 Negative_regulation of Gene_expression of SCNN1G 3 0.32 2.08 0.19
70 INT317078 Regulation of SCNN1G 1 0.04 0.58 0.18
71 INT164291 Regulation of Positive_regulation of SCN5A 2 0.38 0.73 0.15
72 INT293099 Regulation of Gene_expression of Slc12a3 1 0.14 1.53 0.14
73 INT134514 Regulation of Slc12a3 1 0.62 0 0.14
74 INT350601 Regulation of Negative_regulation of ABP1 1 0.04 0.23 0.14
75 INT196671 Positive_regulation of Positive_regulation of SCNN1G 2 0.04 1.04 0.13
76 INT350602 Positive_regulation of Positive_regulation of ABP1 1 0.05 0.24 0.13
77 INT57198 Negative_regulation of Positive_regulation of SCN5A 2 0.30 0.17 0.12
78 INT33738 Protein_catabolism of ABP1 1 0.62 0 0.11
79 INT196674 Transcription of SCNN1G 1 0.04 0.22 0.1
80 INT292545 Negative_regulation of Binding of Scn7a 1 0.03 0 0.1
81 INT67512 Negative_regulation of Negative_regulation of SCN5A 1 0.01 0 0.1
82 INT134513 Negative_regulation of Slc12a3 2 0.37 0 0.09
83 INT196692 Positive_regulation of Gene_expression of SCNN1G 2 0.06 0.35 0.09
84 INT284878 Regulation of Scn5a 2 0.27 1.15 0.09
85 INT249663 Negative_regulation of Phosphorylation of SCN5A 1 0.05 0.74 0.09
86 INT249661 Positive_regulation of Phosphorylation of SCN5A 1 0.06 0.74 0.09
87 INT249660 Phosphorylation of SCN5A 1 0.10 0.73 0.09
88 INT284868 Binding of Scn5a 2 0.36 0.7 0.08
89 INT120695 Regulation of Gene_expression of SCNN1G 1 0.22 0.77 0.08
90 INT351913 Negative_regulation of Localization of Scn7a 1 0.02 1.47 0.08
91 INT134516 Positive_regulation of Gene_expression of Slc12a3 2 0.50 1.23 0.07
92 INT228403 Binding of Slc12a3 2 0.16 0.52 0.07
93 INT196680 Negative_regulation of Positive_regulation of SCNN1G 1 0.04 0.28 0.07
94 INT255040 Positive_regulation of Gene_expression of ABP1 1 0.02 1.01 0.07
95 INT239958 Negative_regulation of Regulation of Scn7a 1 0.04 0.17 0.07
96 INT286583 Localization of PKD2 1 0.35 0.17 0.06
97 INT261879 Binding of PKD2 3 0.13 2.59 0.05
98 INT279816 Negative_regulation of Scn1a 1 0.40 1.31 0.04
99 INT279687 Negative_regulation of Gene_expression of Scn7a 3 0.03 0 0.03
100 INT317082 Positive_regulation of Negative_regulation of SCNN1G 1 0.04 0 0.03
101 INT241245 Negative_regulation of PKD2 2 0.42 2.35 0
102 INT187724 Positive_regulation of Localization of SCN5A 2 0.24 0.15 0
103 INT293112 Negative_regulation of Gene_expression of Slc12a3 1 0.15 3.89 0
104 INT311636 Positive_regulation of Gene_expression of Slc12a3 1 0.23 0.62 0
105 INT317079 Negative_regulation of Binding of SCNN1G 1 0.04 0 0
106 INT284874 Regulation of Transcription of Scn5a 1 0.26 0.33 0
107 INT232493 Negative_regulation of Positive_regulation of PKD2 1 0.23 0.61 0
108 INT261878 Negative_regulation of Binding of PKD2 1 0.14 0.6 0
109 INT191283 Transcription of ABP1 1 0.53 0.44 0
110 INT279824 Positive_regulation of Scn1a 1 0.47 1.22 0
111 INT232491 Positive_regulation of PKD2 1 0.27 0.56 0
112 INT211184 Positive_regulation of Binding of SCN5A 1 0.22 0.48 0
113 INT317080 Binding of SCNN1G 1 0.03 0 0
114 INT191282 Regulation of Gene_expression of ABP1 1 0.35 0.46 0
115 INT296819 Phosphorylation of Scn5a 1 0.82 0.07 0
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