GO:0035815

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Name positive regulation of renal sodium excretion
Categary Process
Go Slim No
Go Link GO:0035815
Unique Molecular Interactions 1007
Total Molecular Interactions 1370
Total Single Events 13352
Pain Genes Associated 32

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of renal sodium excretion. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of renal sodium excretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
2 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
3 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
4 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
5 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
6 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
7 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
8 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
9 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
10 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
11 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
12 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
13 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
14 INT149470 Oxt Regulation of Gene_expression of Avp 1 0.46 1.2 1.92
15 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
16 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
17 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
18 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
19 INT40238 Penk Regulation of Oxt 1 0.04 0 1.83
20 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
21 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
22 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
23 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66
24 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
25 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
26 INT169441 TAC1 Positive_regulation of Tac1 1 0.01 1.7 1.64
27 INT147258 Binding of Tac1 and Penk 1 0.35 0 1.64
28 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
29 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
30 INT42928 Penk Negative_regulation of Localization of Oxt 2 0.03 0 1.57
31 INT73016 PDYN Regulation of TAC1 1 0.29 0.34 1.54
32 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
33 INT64628 Binding of Oxt and Gal 2 0.29 0.29 1.49
34 INT116094 Binding of TACR1 and TFF2 1 0.06 0 1.47
35 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
36 INT5534 Binding of Oxt and Avp 7 0.04 0.6 1.43
37 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
38 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
39 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42
40 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
41 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
42 INT71543 IFNA1 Negative_regulation of Positive_regulation of TAC1 1 0.20 0.19 1.4
43 INT329452 Binding of Tac1 and Oprd1 1 0.01 0.23 1.4
44 INT51160 Binding of TAC1 and Tacr1 2 0.28 0.55 1.38
45 INT26812 SST Regulation of Localization of OXT 1 0.40 0.57 1.37
46 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36
47 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
48 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
49 INT15277 Binding of Tac1 and Gal 1 0.39 0.19 1.35
50 INT185330 Binding of Hrh1 and Tac1 1 0.00 0.1 1.34
51 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
52 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3
53 INT49231 TAC1 Negative_regulation of Penk 1 0.00 0 1.3
54 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
55 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
56 INT95457 Nka1 Positive_regulation of Tacr1 1 0.63 0.29 1.3
57 INT147653 TACR1 Positive_regulation of TRPV1 1 0.02 0.72 1.29
58 INT138213 Mzb1 Regulation of Localization of Tac1 1 0.01 0.41 1.29
59 INT138214 Mzb1 Regulation of Tac1 1 0.01 0.41 1.28
60 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
61 INT162482 Binding of Agt and Vta1 1 0.23 0 1.27
62 INT70226 Binding of TAC1 and B3GAT1 4 0.24 4.5 1.26
63 INT7887 Oprl1 Regulation of Localization of Oxt 2 0.16 0 1.23
64 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
65 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
66 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
67 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
68 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
69 INT209132 Binding of Drd2 and Riok3 1 0.01 1.57 1.16
70 INT48809 Pax3 Negative_regulation of Binding of Tac1 1 0.22 0 1.16
71 INT339331 Binding of TACR1 and SFTPA1 1 0.04 0.12 1.14
72 INT122369 Tacr1 Positive_regulation of Ngf 1 0.30 0.16 1.14
73 INT30359 Pomc Regulation of Localization of Oxt 1 0.03 0 1.13
74 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
75 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
76 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11
77 INT113540 Binding of OPRM1 and Tac1 1 0.04 0.1 1.1
78 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
79 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07
80 INT314136 Binding of TAC1 and SFTPA1 2 0.03 0.78 1.06
81 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
82 INT94205 TACR1 Regulation of Gene_expression of SP5 1 0.04 0.72 1.06
83 INT339333 Binding of TACR1 and TAC4 1 0.48 0.32 1.05
84 INT63181 Oprl1 Regulation of Localization of Tacr1 1 0.06 0.09 1.04
85 INT8416 LIF Regulation of TAC1 1 0.13 0.36 1.04
86 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
87 INT75247 Abat Regulation of Gene_expression of Tacr1 1 0.23 0.41 1.03
88 INT63103 AVP Regulation of OXT 1 0.28 0.68 1.02
89 INT84959 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Tac1 1 0.48 0.59 1.02
90 INT21332 Binding of Drd2 and Gm5195 1 0.01 0.26 1
91 INT209151 OXT Positive_regulation of PNLIP 1 0.08 0.73 0.99
92 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 0.30 0.38 0.99
93 INT73680 KNG1 Positive_regulation of ALB 1 0.51 0.38 0.98
94 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97
95 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97
96 INT303690 KNG1 Positive_regulation of CPOX 1 0.01 0.76 0.96
97 INT149474 Avp Regulation of Gene_expression of Oxt 1 0.27 0.6 0.96
98 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
99 INT66714 Negative_regulation of Binding of BDKRB1 and KNG1 1 0.13 0.22 0.96
100 INT107951 Pax3 Positive_regulation of Tac1 1 0.11 1.21 0.95
101 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
102 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
103 INT51543 Positive_regulation of Binding of Oxt and Penk 1 0.56 0.05 0.94
104 INT314142 Binding of TAC1 and Tacr3 1 0.06 0.73 0.94
105 INT51544 Binding of Oxt and Penk 1 0.54 0.05 0.94
106 INT24938 TAC1 Regulation of Calca 1 0.22 0.35 0.94
107 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92
108 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92
109 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
110 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
111 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
112 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91
113 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89
114 INT84369 Ngf Positive_regulation of KNG1 1 0.04 0.29 0.89
115 INT96008 Binding of KNG1 and EBP 1 0.01 0.15 0.88
116 INT96010 KNG1 Positive_regulation of Binding of MTG1 1 0.32 0.15 0.88
117 INT96009 KNG1 Positive_regulation of MTG1 1 0.32 0.15 0.88
118 INT252881 Crcp Positive_regulation of Gene_expression of Tacr1 1 0.00 0.28 0.88
119 INT24940 TAC1 Regulation of Nka1 1 0.10 0.34 0.87
120 INT121745 Tacr1 Negative_regulation of Positive_regulation of Ephb1 1 0.04 0 0.87
121 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86
122 INT311612 Binding of Drd2 and Sert1 1 0.12 0.65 0.86
123 INT36008 Negative_regulation of Binding of Drd2 and Prl 1 0.01 2.11 0.85
124 INT26528 Prl Regulation of Oxt 1 0.26 0.26 0.85
125 INT69424 Binding of Agt and Oprd1 1 0.14 0 0.84
126 INT113237 Il10 Negative_regulation of Gene_expression of Tacr1 1 0.35 0.81 0.84
127 INT41862 Agtr2 Regulation of Cpe 1 0.00 0 0.84
128 INT41859 Agtr2 Regulation of Cck 1 0.00 0 0.84
129 INT41860 Agtr2 Regulation of Vip 1 0.02 0 0.84
130 INT225690 KNG1 Positive_regulation of TRPV1 1 0.42 0.7 0.83
131 INT193322 KNG1 Positive_regulation of Prh1 1 0.00 0.51 0.83
132 INT64627 Binding of Oxt and Crh 1 0.07 0.1 0.83
133 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
134 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82
135 INT140280 Negative_regulation of Binding of Adora2a and Grina 1 0.21 0.64 0.82
136 INT113240 Il12a Regulation of Transcription of Tacr1 1 0.21 0.79 0.82
137 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
138 INT140281 Binding of Adora2a and Grina 1 0.19 0.64 0.82
139 INT114844 Lgals1 Positive_regulation of TACR1 1 0.16 0.95 0.82
140 INT73032 Cck Negative_regulation of Localization of Oxt 1 0.44 0 0.82
141 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
142 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
143 INT84103 TACR1 Regulation of Nka1 1 0.00 0 0.81
144 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
145 INT113239 Il10 Regulation of Transcription of Tacr1 1 0.45 0.79 0.81
146 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
147 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
148 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
149 INT208946 Positive_regulation of Tacr1 Positive_regulation of Gene_expression of S100a8 1 0.02 1.11 0.8
150 INT101439 Cck Positive_regulation of Agtr2 1 0.24 0.33 0.8
151 INT113238 Il12a Positive_regulation of Transcription of Tacr1 1 0.38 0.78 0.79
152 INT114068 Agtr2 Regulation of Gene_expression of Insr 1 0.15 0.95 0.79
153 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
154 INT132977 Tac1 Positive_regulation of Mapk1 1 0.06 0.17 0.79
155 INT150636 Binding of KNG1 and CD177 1 0.10 0.37 0.79
156 INT92293 Tacr1 Regulation of Tac2 1 0.17 0.07 0.79
157 INT79339 Phax Regulation of Gene_expression of Tacr1 1 0.07 0 0.78
158 INT39673 Binding of Oxt and Esyt1 1 0.04 0 0.78
159 INT213978 Binding of TAC1 and Tac1 1 0.02 0.36 0.78
160 INT164364 Binding of DRD2 and SUGT1 2 0.06 0.33 0.77
161 INT72017 Binding of Adora2a and Ptprg 2 0.07 0 0.77
162 INT166902 NPPB Positive_regulation of TRPA1 1 0.78 0.76 0.77
163 INT148061 Binding of Tacr1 and B4galt4 1 0.01 0.06 0.77
164 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
165 INT95458 Nka1 Positive_regulation of Positive_regulation of Tacr1 1 0.52 0.16 0.77
166 INT148062 Binding of Tacr1 and St3gal3 1 0.01 0.06 0.77
167 INT129415 KNG1 Positive_regulation of Trpv1 1 0.05 0.39 0.76
168 INT42929 Pomc Negative_regulation of Localization of Oxt 1 0.11 0 0.76
169 INT94816 Prkcg Positive_regulation of TACR1 1 0.06 0.1 0.76
170 INT334833 Binding of Drd2 and Ncs1 1 0.05 1.11 0.76
171 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
172 INT151339 Positive_regulation of Binding of Drd2 and P9Ehs1 1 0.11 0.22 0.76
173 INT107028 KNG1 Regulation of Des 1 0.01 1.7 0.76
174 INT151340 Binding of Drd2 and P9Ehs1 1 0.09 0.22 0.75
175 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.11 0 0.75
176 INT332699 Binding of KNG1 and TRGC1 1 0.16 3.37 0.75
177 INT327702 Binding of Comt and Drd2 1 0.28 0.27 0.74
178 INT202909 Binding of Tacr1 and Fig4 1 0.03 0.33 0.74
179 INT41919 Binding of Tacr1 and Trh 1 0.06 0 0.74
180 INT39095 Negative_regulation of Agt Positive_regulation of Localization of Ren 1 0.38 0 0.73
181 INT82041 Positive_regulation of Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.12 0 0.72
182 INT8367 Tacr1 Positive_regulation of Localization of Prss12 1 0.05 0 0.72
183 INT48034 Binding of LH and Oxt 2 0.12 0 0.71
184 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
185 INT73822 TAC1 Positive_regulation of Localization of IL1B 1 0.04 0.56 0.71
186 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
187 INT16437 Ubqln1 Positive_regulation of Localization of Oxt 1 0.03 0 0.7
188 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
189 INT121458 KNG1 Positive_regulation of Localization of Trpv1 1 0.16 0.43 0.69
190 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
191 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
192 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
193 INT207411 Sst Negative_regulation of Gene_expression of Tacr1 1 0.05 0.76 0.69
194 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
195 INT141063 Agt Regulation of Agtr1a 1 0.28 1.18 0.68
196 INT64433 Oxt Negative_regulation of Prl 1 0.05 0 0.68
197 INT79937 TAC1 Positive_regulation of Gene_expression of VCAM1 1 0.20 0.15 0.68
198 INT48031 Binding of Oxt and Pebp1 1 0.01 0 0.68
199 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
200 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of renal sodium excretion. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of renal sodium excretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3579 Localization of Oxt 555 0.81 43.35 292.44
2 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
3 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
4 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
5 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66
6 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7
7 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43
8 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
9 INT2893 Localization of Oxt 219 0.80 28.96 79.43
10 INT451 Regulation of Oxt 142 0.62 22.07 69.42
11 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
12 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26
13 INT7134 Localization of KNG1 127 0.79 65.73 67.97
14 INT7468 Negative_regulation of Localization of Oxt 109 0.59 9.46 66.79
15 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47
16 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71
17 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74
18 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
19 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57
20 INT37219 Gene_expression of TACR1 56 0.78 32.4 54.16
21 INT8690 Localization of Tac1 71 0.80 22.98 50.75
22 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67
23 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3
24 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
25 INT8713 Regulation of Tac1 56 0.60 25.29 45.94
26 INT4776 Localization of TAC1 82 0.78 16.89 45.21
27 INT14853 Negative_regulation of Tac1 80 0.59 30.87 45.06
28 INT4850 Binding of Tac1 57 0.47 14.25 42.17
29 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
30 INT4925 Binding of Tacr1 57 0.48 17.39 38.38
31 INT65125 Gene_expression of Tacr1 81 0.77 23.9 38.35
32 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
33 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
34 INT8837 Positive_regulation of TAC1 59 0.67 21.94 35.97
35 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79
36 INT13501 Binding of Drd2 65 0.48 23.76 35.6
37 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69
38 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
39 INT4727 Regulation of TAC1 60 0.47 6.74 32.83
40 INT3117 Regulation of Oxt 103 0.61 17.93 32.28
41 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
42 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
43 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
44 INT22239 Negative_regulation of TAC1 52 0.57 12.96 31.41
45 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23
46 INT1158 Regulation of Agt 106 0.61 29.4 30.29
47 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
48 INT3076 Regulation of KNG1 52 0.60 20.39 27.89
49 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
50 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19
51 INT3167 Binding of KNG1 48 0.48 23.26 26.77
52 INT11773 Gene_expression of Tac1 56 0.77 10 25.72
53 INT8779 Binding of TAC1 50 0.47 11.19 25.57
54 INT12484 Binding of Drd2 45 0.48 15.17 24.72
55 INT3028 Negative_regulation of Oxt 76 0.58 18.52 24.4
56 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
57 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
58 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
59 INT7715 Regulation of Drd2 35 0.62 10.79 22.3
60 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
61 INT2894 Negative_regulation of Localization of Oxt 43 0.58 4.59 20.85
62 INT49774 Binding of DRD2 48 0.48 17.42 20.73
63 INT41494 Negative_regulation of Gene_expression of Tacr1 25 0.58 11.73 19.91
64 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
65 INT5048 Binding of Edn1 55 0.47 18.86 19.16
66 INT5533 Binding of Oxt 43 0.48 8.69 18.35
67 INT12360 Regulation of Tac1 31 0.61 5.9 18
68 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
69 INT15202 Regulation of Tacr1 26 0.60 9.65 16.48
70 INT2066 Localization of Agt 56 0.80 9.95 16.25
71 INT26729 Negative_regulation of Drd2 28 0.55 9.32 15.17
72 INT9191 Localization of EDN1 94 0.81 57.01 14.78
73 INT11980 Positive_regulation of Tac1 27 0.69 6.17 14.5
74 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
75 INT7469 Positive_regulation of Gene_expression of Oxt 18 0.59 4.7 14.36
76 INT10340 Regulation of Localization of Oxt 30 0.60 2.55 14.3
77 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24
78 INT51158 Positive_regulation of Tacr1 33 0.70 15.22 13.91
79 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
80 INT6365 Localization of Edn1 56 0.81 18.84 13.83
81 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78
82 INT5599 Regulation of Drd2 25 0.52 3.07 13.31
83 INT3962 Regulation of AGT 50 0.62 20.96 13.01
84 INT17974 Positive_regulation of Localization of Oxt 34 0.69 4.45 12.9
85 INT49041 Transcription of Tacr1 25 0.72 12.52 12.8
86 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75
87 INT4199 Binding of Agt 76 0.48 21.06 12.66
88 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
89 INT57580 Positive_regulation of TACR1 18 0.69 9.35 12.47
90 INT398 Localization of AGT 45 0.78 16.97 11.54
91 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47
92 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47
93 INT48691 Negative_regulation of Tacr1 20 0.59 4.96 11.25
94 INT4723 Transcription of Tac1 26 0.71 8.33 11.18
95 INT8589 Positive_regulation of Positive_regulation of Tacr1 14 0.69 7.85 10.86
96 INT8065 Binding of AGT 54 0.48 20.54 10.85
97 INT23519 Positive_regulation of Localization of Tacr1 12 0.41 3.84 10.82
98 INT3546 Binding of Oxt 54 0.48 9.75 10.81
99 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8
100 INT13499 Gene_expression of Agtr2 68 0.76 35.64 10.59
101 INT48806 Negative_regulation of Binding of Tac1 11 0.56 0.83 10.52
102 INT75955 Gene_expression of Drd3 19 0.77 4.39 10.07
103 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
104 INT51168 Localization of TACR1 10 0.80 7.66 9.83
105 INT6361 Localization of Edn1 30 0.81 19.09 9.7
106 INT55014 Positive_regulation of Ednrb 31 0.70 16.61 9.68
107 INT53547 Binding of TACR1 22 0.48 5.03 9.48
108 INT57039 Positive_regulation of Gene_expression of Drd2 16 0.50 1.98 9.48
109 INT17764 Negative_regulation of Drd2 17 0.42 4.63 9.46
110 INT51837 Negative_regulation of TACR1 17 0.43 6.5 9.12
111 INT5939 Regulation of Gene_expression of Oxt 27 0.51 2.84 9.1
112 INT13296 Transcription of Drd2 17 0.66 2.7 9.07
113 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
114 INT12358 Regulation of Gene_expression of Tac1 17 0.60 3.34 8.84
115 INT6682 Regulation of Gene_expression of Drd2 13 0.51 2.17 8.82
116 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81
117 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
118 INT23331 Positive_regulation of Localization of Tac1 10 0.54 4.63 8.76
119 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73
120 INT4984 Positive_regulation of Positive_regulation of Tac1 11 0.50 5.34 8.73
121 INT10237 Binding of EDN1 40 0.48 16 8.48
122 INT76814 Positive_regulation of Gene_expression of Tacr1 13 0.69 6.11 8.42
123 INT81610 Phosphorylation of TACR1 1 0.81 0.76 8.38
124 INT23209 Binding of Adora2a 17 0.38 2.04 8.35
125 INT26815 Regulation of OXT 15 0.46 5.38 8.31
126 INT4940 Negative_regulation of Localization of Tacr1 8 0.37 4.29 8.25
127 INT22700 Positive_regulation of Gene_expression of Tac1 13 0.69 6.89 8.2
128 INT48877 Binding of Tacr1 16 0.43 5.26 8.04
129 INT26551 Positive_regulation of Gene_expression of KNG1 19 0.67 11.05 7.98
130 INT54755 Negative_regulation of Adora2a 17 0.58 2.7 7.75
131 INT51206 Regulation of Gene_expression of Tac1 13 0.45 5.92 7.74
132 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
133 INT18190 Regulation of DRD2 11 0.60 9.01 7.63
134 INT14548 Localization of Tac1 13 0.78 1.43 7.48
135 INT75063 Regulation of Gene_expression of Drd2 10 0.62 2.82 7.38
136 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
137 INT73760 Transcription of Drd2 14 0.72 2.11 7.19
138 INT29583 Positive_regulation of Agtr2 30 0.45 21.47 7.04
139 INT19302 Localization of OXT 31 0.79 3.39 6.92
140 INT12359 Negative_regulation of Tac1 26 0.58 8.16 6.89
141 INT2838 Positive_regulation of Gene_expression of Oxt 27 0.67 6.25 6.83
142 INT11975 Transcription of Tac1 24 0.71 4.06 6.72
143 INT64215 Gene_expression of Drd3 16 0.78 5.27 6.71
144 INT24884 Negative_regulation of Positive_regulation of Tacr1 8 0.43 2.35 6.66
145 INT15674 Positive_regulation of Gene_expression of Tac1 17 0.68 4.97 6.56
146 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55
147 INT62950 Gene_expression of NPPB 73 0.75 65.91 6.54
148 INT24460 Localization of Drd2 12 0.73 2.96 6.46
149 INT24536 Regulation of Localization of Tacr1 5 0.30 3.39 6.44
150 INT78178 Gene_expression of Ednrb 21 0.75 7.1 6.37
151 INT38563 Negative_regulation of Gene_expression of Oxt 18 0.56 2.51 6.23
152 INT86772 Localization of Drd2 14 0.80 1.93 6.17
153 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
154 INT103880 Positive_regulation of DRD2 9 0.67 5.57 5.93
155 INT42799 Positive_regulation of Drd3 11 0.69 1.1 5.92
156 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84
157 INT6681 Positive_regulation of Gene_expression of Drd2 10 0.65 1.78 5.78
158 INT21647 Negative_regulation of Positive_regulation of KNG1 11 0.43 5.54 5.73
159 INT14388 Regulation of TACR1 12 0.45 3.1 5.58
160 INT129645 Negative_regulation of Gene_expression of TAC1 5 0.42 3.33 5.55
161 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5
162 INT63395 Regulation of Regulation of Tacr1 6 0.45 2.26 5.39
163 INT66288 Positive_regulation of Transcription of Tacr1 10 0.70 5.06 5.37
164 INT83014 Binding of Adora2a 13 0.48 5.57 5.33
165 INT32432 Positive_regulation of Binding of Drd2 7 0.67 2.72 5.19
166 INT27805 Regulation of Avpr1a 5 0.60 3.11 5.19
167 INT26280 Negative_regulation of Positive_regulation of Oxt 13 0.52 3.05 5.11
168 INT50330 Positive_regulation of Drd3 7 0.70 0.76 5.08
169 INT89664 Negative_regulation of Adora2a 11 0.59 7.81 5.07
170 INT81609 Positive_regulation of Phosphorylation of TACR1 1 0.60 0.33 4.91
171 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9
172 INT51468 Regulation of Adora2a 8 0.48 1.5 4.84
173 INT14771 Regulation of Localization of Tac1 4 0.48 1.77 4.83
174 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78
175 INT14125 Positive_regulation of Positive_regulation of Drd2 3 0.35 0.85 4.78
176 INT17803 Regulation of Edn1 14 0.54 4.75 4.71
177 INT8838 Positive_regulation of Localization of TAC1 7 0.49 0.86 4.7
178 INT41816 Negative_regulation of Localization of Tac1 5 0.35 1.2 4.66
179 INT24011 Binding of Drd3 13 0.47 3.03 4.64
180 INT58097 Transcription of Oxt 18 0.69 1.62 4.6
181 INT78995 Negative_regulation of Agtr2 26 0.42 13.05 4.56
182 INT29519 Gene_expression of Ednrb 8 0.66 1.99 4.55
183 INT92446 Positive_regulation of Gene_expression of TACR1 4 0.35 2.68 4.5
184 INT71676 Transcription of DRD2 5 0.69 1.19 4.47
185 INT92133 Negative_regulation of Ednrb 8 0.42 1.7 4.44
186 INT17818 Gene_expression of Agtr2 24 0.56 12.96 4.41
187 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
188 INT36007 Negative_regulation of Binding of Drd2 7 0.57 3.22 4.36
189 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
190 INT13741 Positive_regulation of Positive_regulation of Oxt 13 0.56 0.44 4.29
191 INT10849 Negative_regulation of OXT 14 0.48 2.51 4.19
192 INT49217 Positive_regulation of Positive_regulation of KNG1 7 0.41 3.64 4.18
193 INT51540 Positive_regulation of Negative_regulation of Oxt 3 0.47 1.19 4.1
194 INT76714 Binding of Drd3 9 0.37 2.33 4.09
195 INT19300 Positive_regulation of OXT 34 0.43 4.43 4.07
196 INT68099 Positive_regulation of Agtr2 21 0.48 16.63 4.07
197 INT152312 Positive_regulation of Ednrb 7 0.49 1.46 4.04
198 INT50228 Positive_regulation of Positive_regulation of Adora2a 8 0.39 0.1 4
199 INT36772 Positive_regulation of Positive_regulation of Oxt 11 0.69 1.73 3.94
200 INT9822 Binding of Agtr2 9 0.36 3 3.93
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