GO:0035872

From wiki-pain
Jump to: navigation, search
Name nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0035872
Unique Molecular Interactions 414
Total Molecular Interactions 684
Total Single Events 3894
Pain Genes Associated 30

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT164362 Binding of NLRP1 and VTA1 1 0.15 2.37 4.67
2 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
3 INT150392 Binding of MEFV and PSTPIP1 2 0.51 10.49 1.44
4 INT164365 Positive_regulation of Binding of NLRP1 and VTA1 1 0.14 0.6 1.21
5 INT340439 Binding of HLA-DMA and SUGT1 1 0.00 4.1 1.16
6 INT76199 CASP1 Positive_regulation of CEL 1 0.06 0.32 1.14
7 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
8 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
9 INT289173 PYCARD Regulation of MFGE8 1 0.05 0 0.96
10 INT164363 Regulation of Binding of NLRP1 and VTA1 1 0.14 0.45 0.86
11 INT100283 TXN Negative_regulation of Gene_expression of POMC 1 0.54 0.5 0.85
12 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
13 INT132894 CHUK Regulation of Gene_expression of Nos2 1 0.00 0.21 0.79
14 INT164364 Binding of DRD2 and SUGT1 2 0.06 0.33 0.77
15 INT346234 MAP2K6 Positive_regulation of MAPK14 1 0.44 1.65 0.77
16 INT142057 NLRP1 Regulation of Gene_expression of Fos 1 0.17 0 0.76
17 INT91655 SLC8A1 Negative_regulation of CASP1 1 0.02 0.43 0.75
18 INT216668 Positive_regulation of NLRP1 Regulation of Vta1 1 0.00 0 0.73
19 INT281241 Positive_regulation of P2RX7 Negative_regulation of Gene_expression of P2rx3 1 0.03 0.79 0.71
20 INT278812 PYCARD Positive_regulation of VTA1 1 0.09 0.11 0.71
21 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
22 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
23 INT134652 Binding of MC1R and SUGT1 1 0.02 0.84 0.68
24 INT270763 IL1B Negative_regulation of IKBKB 1 0.04 1.13 0.66
25 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
26 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
27 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
28 INT165844 Binding of ATF4 and HSP90AB1 1 0.15 0.34 0.61
29 INT179203 NLRP1 Regulation of Gene_expression of TNF 1 0.31 1.73 0.6
30 INT159125 Binding of OPRM1 and SUGT1 1 0.03 0.31 0.57
31 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
32 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
33 INT76200 CASP1 Positive_regulation of Gene_expression of PTGS1 1 0.05 0.16 0.54
34 INT282821 TACR1 Regulation of P2RX7 1 0.01 2.06 0.54
35 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
36 INT162720 PEG3 Negative_regulation of Positive_regulation of CASP8 1 0.00 0.71 0.52
37 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
38 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
39 INT251730 Binding of CD70 and SUGT1 1 0.01 0.85 0.49
40 INT115184 Regulation of CASP1 Positive_regulation of MAPK9 1 0.09 0 0.49
41 INT150391 Binding of MEFV and PYCARD 4 0.14 3 0.48
42 INT115183 CASP1 Positive_regulation of Positive_regulation of MAPK9 1 0.16 0 0.48
43 INT210160 Binding of TNFRSF8 and TXN 1 0.47 4.16 0.48
44 INT115185 CASP1 Positive_regulation of MAPK9 1 0.15 0 0.48
45 INT231713 Binding of SUGT1 and GPR174 1 0.00 0.82 0.47
46 INT338086 PYCARD Positive_regulation of TCEA1 1 0.10 0 0.47
47 INT338083 Binding of LEFTY1 and PYCARD 1 0.02 0 0.46
48 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45
49 INT155086 CASP1 Negative_regulation of DAXX 1 0.21 1.26 0.45
50 INT155085 CASP1 Negative_regulation of CASP8 1 0.29 1.25 0.44
51 INT346237 MAP2K6 Positive_regulation of MAP2K3 1 0.49 1 0.44
52 INT121850 CASP8 Positive_regulation of Protein_catabolism of BID 2 0.21 1.81 0.43
53 INT112800 CASP1 Positive_regulation of Gene_expression of CCL2 1 0.04 0.48 0.43
54 INT146276 Binding of P2RX4 and P2RX7 1 0.38 0.38 0.43
55 INT36743 NLRP3 Regulation of Mbp 1 0.01 0 0.43
56 INT100282 TXN Negative_regulation of Transcription of POMC 1 0.54 0.39 0.43
57 INT228323 PYCARD Positive_regulation of FIG4 1 0.17 0 0.42
58 INT121848 AKT1 Regulation of CASP8 1 0.18 0.52 0.41
59 INT95660 MEFV Negative_regulation of UBXN11 1 0.36 0.52 0.41
60 INT121855 CASP8 Regulation of ROS1 1 0.05 0.52 0.41
61 INT121849 CASP8 Positive_regulation of CYCS 1 0.35 0.48 0.4
62 INT79577 APP Negative_regulation of PENK 1 0.12 0.35 0.4
63 INT121852 CASP8 Positive_regulation of Localization of CYCS 1 0.32 0.48 0.4
64 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39
65 INT338085 Binding of PYCARD and GOPC 1 0.05 0 0.39
66 INT91656 SLC8A1 Negative_regulation of Positive_regulation of CASP1 1 0.01 0.2 0.38
67 INT278813 Binding of NOVA2 and PYCARD 1 0.13 0 0.38
68 INT91652 Negative_regulation of SLC8A1 Negative_regulation of CASP1 1 0.02 0.21 0.37
69 INT78854 APP Positive_regulation of Localization of IL6 1 0.14 0.79 0.37
70 INT322015 Binding of IL1B and P2RX7 1 0.07 1 0.37
71 INT179201 NLRP1 Regulation of Gene_expression of IL10 1 0.06 0.77 0.36
72 INT4382 RIPK2 Regulation of INS 1 0.12 0.58 0.36
73 INT179202 NLRP1 Regulation of Gene_expression of IL6 1 0.07 0.77 0.36
74 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35
75 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
76 INT191128 Positive_regulation of P2RX7 Positive_regulation of Localization of Il1b 1 0.02 0.71 0.34
77 INT346228 MAP2K6 Positive_regulation of Positive_regulation of MAPK14 1 0.44 0.68 0.34
78 INT4381 RIPK2 Positive_regulation of Localization of INS 1 0.13 0.53 0.34
79 INT217041 TNF Positive_regulation of Gene_expression of P2RX7 1 0.50 0.81 0.34
80 INT346236 Binding of MAPK14 and MAP2K6 1 0.32 0.65 0.33
81 INT341794 Binding of SUGT1 and CEP68 1 0.00 1.1 0.33
82 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32
83 INT263978 Binding of ADRB2 and TNFAIP3 1 0.01 0.5 0.32
84 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32
85 INT147434 Psenen Positive_regulation of APP 1 0.01 0.58 0.32
86 INT289178 Regulation of PYCARD Regulation of MFGE8 1 0.05 0 0.32
87 INT274569 Binding of PSTPIP2 and PSTPIP1 1 0.50 2.07 0.31
88 INT289175 PYCARD Regulation of behavior 1 0.03 0 0.31
89 INT334879 CASP1 Regulation of IL1B 1 0.03 1.63 0.31
90 INT112797 Positive_regulation of CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.3
91 INT219151 IL18 Positive_regulation of CASP1 1 0.01 1.05 0.3
92 INT191499 CMA1 Positive_regulation of NLRP3 1 0.02 0.42 0.3
93 INT191502 Binding of CMA1 and NLRP3 1 0.01 0.42 0.3
94 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
95 INT289179 PYCARD Regulation of TW 1 0.02 0 0.3
96 INT112795 Positive_regulation of CASP1 Positive_regulation of MAPK8 1 0.02 0.16 0.3
97 INT112799 Positive_regulation of CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.3
98 INT112803 CASP1 Positive_regulation of MAPK8 1 0.02 0.16 0.29
99 INT319220 FSIP1 Regulation of APP 1 0.29 1.46 0.29
100 INT112805 CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.29
101 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28
102 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
103 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28
104 INT323710 TRAF6 Regulation of MIR146A 1 0.06 0.55 0.28
105 INT116595 CASP1 Positive_regulation of IL6 1 0.07 0.46 0.28
106 INT116591 CASP1 Positive_regulation of PTGER2 1 0.01 0.46 0.28
107 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28
108 INT79592 Binding of APP and Reg1 1 0.01 0.16 0.27
109 INT219156 NLRP3 Positive_regulation of IL1B 1 0.01 1.03 0.27
110 INT191497 Binding of REN and NLRP3 1 0.02 0.55 0.27
111 INT191504 CPN2 Positive_regulation of NLRP3 1 0.00 0.37 0.27
112 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
113 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
114 INT219193 Nlrp3 Positive_regulation of Positive_regulation of NLRP3 1 0.24 1.03 0.26
115 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
116 INT322021 Negative_regulation of CASP1 Positive_regulation of IL1B 1 0.04 0.13 0.26
117 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26
118 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26
119 INT114244 Cpox Negative_regulation of Gene_expression of APP 1 0.00 0.7 0.25
120 INT121250 MEFV Positive_regulation of Binding of ANXA5 1 0.41 0.67 0.25
121 INT191498 Binding of CTSG and NLRP3 1 0.07 0.37 0.25
122 INT261976 Binding of PDCD1 and SUGT1 1 0.00 1.3 0.25
123 INT191496 CTSG Positive_regulation of NLRP3 1 0.09 0.37 0.25
124 INT257776 Phosphorylation of AR Positive_regulation of Localization of TAB2 1 0.26 0.38 0.24
125 INT290376 Binding of CSF1R and MEFV 1 0.29 0.31 0.24
126 INT100279 TXN Negative_regulation of Gene_expression of HSP90B2P 1 0.13 0.3 0.24
127 INT191536 Klk1c2 Positive_regulation of NLRP3 1 0.02 0.36 0.24
128 INT191537 Binding of Klk1c2 and NLRP3 1 0.02 0.36 0.24
129 INT100280 TXN Positive_regulation of Gene_expression of MC1R 1 0.33 0.22 0.24
130 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
131 INT290378 NOD2 Negative_regulation of TLR2 1 0.27 0.83 0.23
132 INT290377 NOD2 Negative_regulation of Positive_regulation of TLR2 1 0.24 0.95 0.23
133 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
134 INT112794 CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.23
135 INT250553 Binding of RS1 and SUGT1 3 0.00 3.36 0.22
136 INT274584 Binding of PSTPIP1 and PYCARD 1 0.13 1.34 0.22
137 INT70082 Binding of APP and TGM1 1 0.00 1.22 0.22
138 INT289174 PYCARD Positive_regulation of MFGE8 1 0.05 0 0.21
139 INT112798 CASP1 Positive_regulation of CCL2 1 0.02 0.19 0.21
140 INT341778 DBT Positive_regulation of MAP2K6 1 0.00 0 0.21
141 INT258456 PYCARD Negative_regulation of Localization of Tms 1 0.02 0.05 0.21
142 INT322011 BSG Regulation of P2RX7 1 0.00 0.48 0.21
143 INT274578 Binding of ABL1 and PSTPIP1 1 0.07 1.55 0.21
144 INT258455 Tms Negative_regulation of Localization of PYCARD 1 0.02 0.05 0.21
145 INT349668 Binding of HRH1 and PYCARD 1 0.00 0.37 0.21
146 INT91654 Negative_regulation of CASP1 Negative_regulation of IL1B 1 0.46 0.15 0.2
147 INT91653 Negative_regulation of CASP1 Negative_regulation of IL18 1 0.39 0.15 0.2
148 INT55252 Binding of CCK and RIPK2 1 0.40 0 0.2
149 INT175948 TNF Positive_regulation of Positive_regulation of CASP8 1 0.02 1.12 0.2
150 INT175947 TNFSF10 Positive_regulation of Positive_regulation of CASP8 1 0.01 1.12 0.2
151 INT100284 TXN Positive_regulation of Gene_expression of POMC 1 0.65 0 0.19
152 INT306067 Binding of ADH5 and CYLD 1 0.02 3.13 0.19
153 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19
154 INT289176 PYCARD Regulation of Localization of MFGE8 1 0.05 0 0.18
155 INT289177 PYCARD Regulation of Gene_expression of TW 1 0.03 0 0.18
156 INT319173 TXN Positive_regulation of Gene_expression of SOD2 1 0.23 0.1 0.18
157 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
158 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
159 INT349659 PYCARD Positive_regulation of ADRB2 1 0.06 0.19 0.17
160 INT233904 NLRP3 Positive_regulation of AGT 1 0.06 0.81 0.17
161 INT155232 TXNIP Regulation of BAX 1 0.23 0.15 0.17
162 INT178336 Binding of SUGT1 and Chdh 1 0.00 0.98 0.17
163 INT341813 Binding of SUGT1 and Aia1 1 0.00 0.48 0.16
164 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
165 INT23165 Binding of NLRP3 and BDNF-AS 1 0.01 0.83 0.16
166 INT23164 Negative_regulation of Binding of NLRP3 and BDNF-AS 1 0.01 0.83 0.16
167 INT118257 Binding of ENPP1 and SUGT1 1 0.00 0.87 0.16
168 INT207253 INS Negative_regulation of TXNIP 1 0.45 1.2 0.15
169 INT318305 Binding of NOD2 and NLRP3 1 0.08 1.76 0.15
170 INT318306 Binding of DPEP1 and NLRP3 1 0.03 1.77 0.15
171 INT137647 PYCARD Positive_regulation of NLN 1 0.02 0.08 0.15
172 INT246365 CALM1 Regulation of MAP2K6 1 0.00 0.34 0.15
173 INT137646 Negative_regulation of PYCARD Positive_regulation of NLN 1 0.02 0.08 0.15
174 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14
175 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
176 INT130923 HMHA1 Positive_regulation of Protein_catabolism of CASP8 1 0.04 1.37 0.14
177 INT97517 Binding of PYCARD and Mefv 1 0.07 0.78 0.14
178 INT293867 Binding of COL2A1 and MEFV 1 0.01 0.52 0.14
179 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
180 INT34431 NLRP3 Positive_regulation of Localization of POMC 1 0.41 0.31 0.14
181 INT130920 HMHA1 Positive_regulation of CASP8 1 0.04 1.36 0.14
182 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
183 INT274568 Binding of MEFV and PSTPIP2 1 0.45 0.61 0.13
184 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
185 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
186 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
187 INT150389 Binding of GFRA1 and MEFV 1 0.02 0.85 0.12
188 INT150387 Binding of MEFV and TNF 1 0.31 0.85 0.12
189 INT150390 Binding of CD27 and MEFV 1 0.27 0.85 0.12
190 INT207254 ZNF236 Positive_regulation of TXNIP 1 0.03 0.68 0.12
191 INT201754 CASP8 Positive_regulation of Casp3 1 0.00 0.47 0.12
192 INT322037 Binding of P2RX7 and Myh1 1 0.06 0 0.12
193 INT298829 Binding of LCT and SUGT1 1 0.00 0.39 0.11
194 INT70084 Negative_regulation of Binding of APP and TGM1 1 0.00 0.61 0.11
195 INT139787 Negative_regulation of TNFAIP8 Positive_regulation of IKBKG 1 0.10 0.89 0.11
196 INT139783 TNFAIP8 Positive_regulation of IKBKG 1 0.12 0.88 0.11
197 INT70083 TGM1 Positive_regulation of Binding of APP 1 0.00 0.61 0.11
198 INT139786 TNFAIP8 Positive_regulation of Phosphorylation of IKBKG 1 0.12 0.89 0.11
199 INT139792 TNFAIP8 Positive_regulation of Protein_catabolism of IKBKG 1 0.12 0.89 0.11
200 INT123101 Binding of APP and Ache 1 0.07 0.32 0.11

Single Events

The table below shows the top 100 pain related interactions that have been reported for nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
2 INT151758 Gene_expression of PYCARD 91 0.63 14.54 24.27
3 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
4 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
5 INT164366 Localization of NLRP1 26 0.71 5.9 16.54
6 INT3002 Binding of SUGT1 62 0.24 55.9 14.91
7 INT127046 Gene_expression of P2RX7 65 0.78 34.28 14.76
8 INT29745 Binding of APP 47 0.48 26.49 12.4
9 INT145425 Positive_regulation of NLRP1 19 0.47 6.93 12.09
10 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08
11 INT137980 Positive_regulation of P2RX7 30 0.67 22.49 10
12 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47
13 INT41569 Regulation of APP 32 0.62 17.15 9.4
14 INT71174 Gene_expression of CASP1 44 0.75 30.3 9.37
15 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
16 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
17 INT97516 Binding of PYCARD 46 0.36 7.06 7.85
18 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36
19 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
20 INT12771 Positive_regulation of IKBKG 27 0.69 5.99 7.02
21 INT1766 Negative_regulation of PYCARD 25 0.37 6.54 6.76
22 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
23 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47
24 INT13406 Negative_regulation of CASP1 25 0.57 10.61 6.36
25 INT137052 Positive_regulation of PYCARD 30 0.43 4.72 6.17
26 INT17641 Gene_expression of NLRP1 33 0.73 8.85 6.02
27 INT81049 Positive_regulation of CASP1 44 0.67 19.97 5.69
28 INT166765 Localization of PYCARD 21 0.70 3.89 5.66
29 INT15542 Negative_regulation of CASP8 20 0.41 17.3 5.63
30 INT84909 Positive_regulation of SUGT1 22 0.08 22.01 5.43
31 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32
32 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
33 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
34 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
35 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
36 INT84911 Gene_expression of SUGT1 43 0.11 19.85 4.54
37 INT133231 Regulation of PYCARD 18 0.39 5.02 4.44
38 INT85126 Negative_regulation of MAP2K6 19 0.39 12.12 4.39
39 INT58003 Localization of APP 32 0.80 13.75 4.2
40 INT12772 Positive_regulation of Positive_regulation of IKBKG 9 0.69 0.84 4.12
41 INT127047 Negative_regulation of P2RX7 10 0.39 7.17 4.01
42 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95
43 INT99821 Negative_regulation of Gene_expression of APP 20 0.42 15.21 3.94
44 INT99819 Negative_regulation of Positive_regulation of APP 6 0.58 4.41 3.64
45 INT125622 Regulation of NLRP1 7 0.44 1.84 3.62
46 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57
47 INT119420 Phosphorylation of MAP2K6 8 0.79 4.89 3.52
48 INT70089 Negative_regulation of Binding of APP 7 0.59 6.45 3.44
49 INT150395 Binding of MEFV 55 0.44 31.18 3.42
50 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
51 INT12770 Negative_regulation of Positive_regulation of IKBKG 7 0.56 0.34 3.02
52 INT191120 Regulation of P2RX7 8 0.41 5.29 2.96
53 INT103910 Binding of NOD2 19 0.47 12.24 2.93
54 INT137978 Localization of P2RX7 6 0.73 5.04 2.84
55 INT6025 Negative_regulation of RIPK2 4 0.57 0.96 2.82
56 INT19421 Positive_regulation of RIPK2 6 0.49 5.63 2.72
57 INT162792 Gene_expression of NOD1 19 0.71 6.11 2.71
58 INT53443 Gene_expression of IKBKG 15 0.65 7.5 2.71
59 INT209889 Gene_expression of TRAF6 13 0.63 6.85 2.67
60 INT156016 Binding of BCL2L1 10 0.36 7.42 2.64
61 INT15543 Gene_expression of CASP8 32 0.75 25.6 2.61
62 INT257950 Regulation of Localization of NLRP1 3 0.08 0.27 2.6
63 INT164367 Negative_regulation of Localization of NLRP1 3 0.34 1.43 2.5
64 INT102646 Positive_regulation of MAP2K6 3 0.63 4.37 2.44
65 INT12769 Localization of IKBKG 6 0.15 1.66 2.43
66 INT162513 Regulation of Protein_catabolism of APP 5 0.51 1.79 2.36
67 INT10612 Localization of NLRP3 13 0.78 8.91 2.27
68 INT97748 Positive_regulation of BCL2L1 12 0.67 9.83 2.26
69 INT91836 Negative_regulation of Gene_expression of BCL2L1 9 0.49 8.59 2.25
70 INT132893 Binding of CHUK 1 0.00 0.63 2.25
71 INT102752 Positive_regulation of Gene_expression of BCL2L1 14 0.67 13.8 2.19
72 INT137972 Binding of P2RX7 12 0.36 8.01 2.18
73 INT291336 Gene_expression of MAP2K6 4 0.70 7.8 2.13
74 INT95592 Positive_regulation of Gene_expression of CASP1 15 0.48 13.06 2.1
75 INT149669 Positive_regulation of MEFV 12 0.46 14.17 2.07
76 INT155234 Gene_expression of TXNIP 48 0.77 24.4 2.05
77 INT142056 Binding of NLRP1 7 0.47 1.7 2.02
78 INT69703 Gene_expression of TXN 20 0.71 3.57 2.01
79 INT132892 Positive_regulation of CHUK 3 0.08 1.62 2.01
80 INT24453 Binding of NLRP3 18 0.48 13.7 1.93
81 INT174653 Localization of MEFV 15 0.70 12.06 1.93
82 INT71173 Negative_regulation of Gene_expression of CASP1 5 0.36 3.17 1.84
83 INT117221 Positive_regulation of Gene_expression of NOD2 7 0.65 4.39 1.83
84 INT162793 Regulation of NOD2 6 0.45 7.61 1.78
85 INT119422 Negative_regulation of Phosphorylation of MAP2K6 3 0.38 2.09 1.76
86 INT141385 Positive_regulation of Gene_expression of P2RX7 7 0.62 3.95 1.73
87 INT183147 Positive_regulation of Gene_expression of MEFV 6 0.50 4.67 1.73
88 INT97749 Regulation of BCL2L1 10 0.41 9.72 1.65
89 INT15544 Regulation of CASP8 6 0.41 5.83 1.63
90 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
91 INT132890 Positive_regulation of Binding of CHUK 1 0.00 0.44 1.6
92 INT132891 Gene_expression of CHUK 1 0.01 0.47 1.58
93 INT23171 Negative_regulation of NLRP3 7 0.37 4.15 1.53
94 INT58004 Positive_regulation of Localization of APP 5 0.46 2.1 1.5
95 INT216666 Positive_regulation of Localization of NLRP1 2 0.09 0.5 1.49
96 INT100286 Localization of TXN 21 0.73 5.13 1.48
97 INT109916 Positive_regulation of Positive_regulation of MAP2K6 2 0.45 2.28 1.45
98 INT95338 Positive_regulation of Positive_regulation of CASP1 9 0.49 4.61 1.43
99 INT34912 Regulation of IKBKG 5 0.08 2.41 1.42
100 INT125796 Regulation of Gene_expression of APP 8 0.59 5.95 1.41
101 INT140858 Negative_regulation of SUGT1 9 0.05 8.41 1.4
102 INT141529 Regulation of Positive_regulation of APP 3 0.44 0.31 1.34
103 INT117219 Positive_regulation of NOD2 9 0.69 4.66 1.31
104 INT15541 Positive_regulation of Negative_regulation of CASP8 2 0.31 1.23 1.31
105 INT136574 Regulation of TNFAIP3 2 0.11 1.33 1.3
106 INT39144 Gene_expression of RIPK2 5 0.75 2.56 1.27
107 INT228328 Positive_regulation of Gene_expression of PYCARD 7 0.34 0.27 1.23
108 INT267652 Negative_regulation of Gene_expression of PYCARD 6 0.37 2.35 1.22
109 INT1941 Binding of PSTPIP1 36 0.48 5.92 1.16
110 INT191527 Positive_regulation of Gene_expression of NLRP3 6 0.50 8.65 1.15
111 INT119348 Binding of IKBKG 7 0.15 4.03 1.14
112 INT135899 Regulation of Binding of APP 3 0.45 1.22 1.14
113 INT7817 Binding of CASP1 7 0.19 1.26 1.13
114 INT135615 Positive_regulation of IKBKB 3 0.59 6.16 1.1
115 INT70021 Localization of BCL2 23 0.74 21.6 1.09
116 INT128496 Regulation of CASP1 5 0.38 3.4 1.09
117 INT91658 Localization of CASP1 5 0.77 0.89 1.04
118 INT307280 Regulation of Gene_expression of PYCARD 2 0.39 0.27 1.02
119 INT191121 Regulation of Gene_expression of P2RX7 3 0.36 3.69 0.99
120 INT154227 Regulation of Gene_expression of NOD2 3 0.44 3.38 0.99
121 INT117435 Negative_regulation of IKBKB 3 0.37 2.67 0.97
122 INT19422 Protein_catabolism of RIPK2 2 0.86 0.62 0.97
123 INT36850 Negative_regulation of Negative_regulation of RIPK2 1 0.57 0 0.97
124 INT156976 Gene_expression of TNFAIP3 4 0.65 5.25 0.93
125 INT150546 Positive_regulation of Phosphorylation of MAP2K6 3 0.49 1.14 0.93
126 INT215567 Positive_regulation of Positive_regulation of P2RX7 2 0.45 0.07 0.93
127 INT156015 Negative_regulation of Protein_catabolism of BCL2L1 1 0.42 1.23 0.93
128 INT156014 Protein_catabolism of BCL2L1 1 0.64 1.23 0.93
129 INT38426 Regulation of RIPK2 3 0.60 0.62 0.91
130 INT42076 Regulation of Negative_regulation of RIPK2 1 0.44 0.91 0.91
131 INT156017 Positive_regulation of Binding of BCL2L1 1 0.49 1.21 0.91
132 INT69705 Positive_regulation of TXN 8 0.63 2.35 0.89
133 INT181177 Gene_expression of CYLD 5 0.69 24.96 0.89
134 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
135 INT162514 Positive_regulation of Regulation of APP 1 0.41 0.37 0.86
136 INT347182 Negative_regulation of TNFAIP3 3 0.23 5.6 0.84
137 INT99375 Positive_regulation of Binding of APP 3 0.61 1.63 0.83
138 INT159126 Localization of SUGT1 3 0.06 1.76 0.81
139 INT228326 Positive_regulation of Localization of PYCARD 3 0.41 0 0.8
140 INT70019 Binding of BCL2 25 0.47 17.55 0.79
141 INT210193 Binding of TXN 31 0.44 6.88 0.78
142 INT346246 Positive_regulation of Gene_expression of MAP2K6 1 0.45 1.74 0.78
143 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
144 INT278119 Positive_regulation of Localization of P2RX7 2 0.45 1.14 0.77
145 INT118078 Phosphorylation of APP 10 0.79 2.5 0.76
146 INT99820 Negative_regulation of Localization of APP 2 0.37 0.75 0.76
147 INT151468 Regulation of MAP2K6 2 0.11 0.68 0.74
148 INT115293 Regulation of Gene_expression of TXN 2 0.19 0.78 0.73
149 INT207285 Positive_regulation of Gene_expression of TXNIP 1 0.69 9.53 0.73
150 INT128497 Regulation of Gene_expression of CASP1 4 0.38 2.02 0.72
151 INT153297 Regulation of MEFV 6 0.40 11.09 0.71
152 INT141528 Regulation of Localization of APP 2 0.52 0.4 0.67
153 INT264003 Positive_regulation of Transcription of TNFAIP3 1 0.38 1.01 0.65
154 INT263996 Transcription of TNFAIP3 1 0.39 0.99 0.64
155 INT36742 Regulation of NLRP3 2 0.16 0 0.63
156 INT244153 Positive_regulation of Gene_expression of NOD1 1 0.46 1.36 0.63
157 INT222205 Positive_regulation of PSTPIP1 8 0.69 4.69 0.62
158 INT244161 Positive_regulation of NOD1 4 0.64 1.83 0.62
159 INT15981 Positive_regulation of Positive_regulation of NLRP3 2 0.44 1.02 0.62
160 INT91330 Regulation of Localization of IKBKG 1 0.01 0.76 0.61
161 INT91328 Regulation of Gene_expression of IKBKG 1 0.01 0.75 0.61
162 INT118077 Negative_regulation of Phosphorylation of APP 1 0.07 0.74 0.61
163 INT323751 Gene_expression of IRAK1 3 0.44 1.33 0.6
164 INT165847 Positive_regulation of HSP90AB1 1 0.60 0.31 0.6
165 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
166 INT58742 Localization of MAP2K6 1 0.61 0.16 0.58
167 INT125867 Protein_catabolism of CASP8 9 0.65 8.5 0.57
168 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
169 INT165849 Protein_catabolism of HSP90AB1 1 0.56 0.28 0.56
170 INT225462 Positive_regulation of Positive_regulation of APP 3 0.44 1.41 0.55
171 INT162791 Regulation of NOD1 2 0.13 0.58 0.55
172 INT103638 Negative_regulation of MEFV 7 0.39 5.88 0.54
173 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
174 INT179205 Regulation of Gene_expression of NLRP1 1 0.18 2.8 0.54
175 INT162721 Negative_regulation of Positive_regulation of CASP8 3 0.12 3.17 0.52
176 INT183144 Positive_regulation of Localization of MEFV 2 0.42 2.61 0.51
177 INT91661 Negative_regulation of Positive_regulation of CASP1 2 0.41 0.35 0.5
178 INT19420 Positive_regulation of Positive_regulation of RIPK2 1 0.49 0.59 0.5
179 INT115195 Negative_regulation of Localization of CASP1 1 0.16 0 0.48
180 INT135620 Regulation of IKBKB 1 0.39 1.23 0.48
181 INT12768 Negative_regulation of Localization of IKBKG 1 0.07 0 0.48
182 INT117436 Binding of IKBKB 2 0.26 1.44 0.47
183 INT155236 Negative_regulation of TXN 5 0.53 0.66 0.46
184 INT38738 Localization of RIPK2 2 0.68 0.07 0.45
185 INT346258 Negative_regulation of Gene_expression of MAP2K6 1 0.38 1.08 0.45
186 INT346260 Regulation of Gene_expression of MAP2K6 1 0.41 1.09 0.45
187 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
188 INT333195 Negative_regulation of Gene_expression of NLRP1 1 0.06 0.32 0.44
189 INT222266 Transcription of NOD2 5 0.68 0.76 0.43
190 INT323739 Regulation of IRAK1 3 0.23 1.73 0.43
191 INT270000 Localization of IRAK1 3 0.73 0.82 0.43
192 INT210194 Positive_regulation of Gene_expression of TXN 1 0.46 1.17 0.43
193 INT100287 Regulation of TXN 2 0.41 0.62 0.42
194 INT343891 Positive_regulation of Gene_expression of IRAK1 1 0.23 0.3 0.42
195 INT209891 Regulation of Gene_expression of TRAF6 2 0.22 1.4 0.41
196 INT91665 Positive_regulation of Localization of CASP1 2 0.48 0.27 0.4
197 INT37187 Positive_regulation of Localization of IKBKG 1 0.10 0.35 0.4
198 INT181179 Binding of CYLD 4 0.43 7.06 0.39
199 INT244159 Transcription of NLRP3 3 0.64 5.61 0.39
200 INT217017 Transcription of P2RX7 1 0.27 0.36 0.39
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox