GO:0035909

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Name aorta morphogenesis
Categary Process
Go Slim No
Go Link GO:0035909
Unique Molecular Interactions 69
Total Molecular Interactions 110
Total Single Events 505
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for aorta morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for aorta morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
2 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
3 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
4 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
5 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
6 INT334013 Ccl25 Positive_regulation of Gene_expression of Lrp1 1 0.07 0.98 0.56
7 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
8 INT146113 Binding of Adra2a and Lrp1 1 0.01 1.07 0.48
9 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
10 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
11 INT316672 Binding of LRP1 and SFTPD 1 0.35 0.96 0.37
12 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
13 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
14 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
15 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
16 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
17 INT220635 Binding of Lrp1 and Kat5 2 0.09 0.71 0.25
18 INT198926 Binding of Apbb1 and Lrp1 5 0.12 2.18 0.24
19 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
20 INT306425 Positive_regulation of Binding of TBX1 and VCF 1 0.02 1.15 0.18
21 INT306426 Binding of TBX1 and VCF 1 0.01 1.09 0.17
22 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
23 INT144027 Binding of Slc6a4 and Pdgfrb 1 0.23 0.25 0.14
24 INT192330 UBR7 Negative_regulation of Positive_regulation of PDGFRB 1 0.01 0.54 0.12
25 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
26 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
27 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
28 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
29 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
30 INT308666 Binding of Lrp1 and Chol1 1 0.10 0.69 0.09
31 INT244639 AGK Negative_regulation of PDGFRB 1 0.01 0.69 0.08
32 INT308655 Binding of Lrp1 and Gopc 1 0.01 0.49 0.07
33 INT298006 CHDM Positive_regulation of Gene_expression of PDGFRB 1 0.16 1.08 0.07
34 INT192329 UBR7 Negative_regulation of Phosphorylation of PDGFRB 1 0.01 0.06 0.07
35 INT279291 PDGFA Positive_regulation of PDGFRB 1 0.16 1.02 0.06
36 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
37 INT279287 PDGFRB Regulation of CDCP1 1 0.01 0.98 0.05
38 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
39 INT202310 Binding of PDGFB and Pdgfrb 1 0.11 0.39 0.04
40 INT292092 Binding of PDGFRB and TXK 1 0.05 1.53 0.04
41 INT311730 Binding of Plat and Lrp1 1 0.14 0.65 0.04
42 INT223086 Binding of Pdgfb and Pdgfrb 1 0.33 0.46 0.04
43 INT292079 Negative_regulation of Binding of PDGFRB and TXK 1 0.06 1.54 0.04
44 INT198919 Binding of Lrp1 and Lrpap1 1 0.07 0 0.04
45 INT198921 Binding of App and Lrp1 3 0.32 2.7 0.03
46 INT356102 Negative_regulation of Binding of App and Lrp1 1 0.32 0.71 0.03
47 INT272596 Binding of Dlg4 and Lrp1 1 0.16 0 0.03
48 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
49 INT279277 PDGFB Positive_regulation of PDGFRB 1 0.14 0.52 0.03
50 INT220636 Binding of Lrp1 and Bace1 2 0.32 0.62 0
51 INT209984 Binding of LDLR and LRP1 1 0.08 0 0
52 INT356108 App Positive_regulation of Positive_regulation of Lrp1 1 0.43 0.52 0
53 INT347124 Binding of FZD1 and Lrp1 1 0.11 0.24 0
54 INT356095 Lrp1 Positive_regulation of App 1 0.37 0.53 0
55 INT356091 Lrp1 Positive_regulation of Positive_regulation of App 1 0.43 0.52 0
56 INT292091 MIR1200 Negative_regulation of PDGFRB 1 0.01 1.24 0
57 INT314866 Binding of Six1 and Sall1 1 0.39 0.76 0
58 INT209985 Binding of LRP1 and LTF 1 0.01 0 0
59 INT198927 Lrp1 Regulation of App 1 0.14 0.42 0
60 INT279283 TXK Regulation of PDGFRB 1 0.06 0.68 0
61 INT347123 Binding of Axin2 and Lrp1 1 0.08 0.2 0
62 INT268398 Binding of LRP1 and Wnt2 1 0.01 0.36 0
63 INT213556 Binding of Eya1 and Six1 1 0.41 0.48 0
64 INT295426 Binding of KIT and PDGFRB 1 0.24 0.4 0
65 INT277703 Binding of Pdgfrb and Pdgfb 1 0.02 0.23 0
66 INT205612 Gm6668 Negative_regulation of Pdgfrb 1 0.00 1.57 0
67 INT284184 Binding of Akt1 and Pdgfrb 1 0.00 0.14 0
68 INT356104 Positive_regulation of Binding of App and Lrp1 1 0.40 0.52 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for aorta morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in aorta morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
2 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09
3 INT137908 Phosphorylation of Pdgfrb 14 0.81 8.44 2.45
4 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2
5 INT137906 Positive_regulation of Phosphorylation of Pdgfrb 6 0.50 2.55 1.94
6 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92
7 INT198885 Gene_expression of Lrp1 33 0.57 10.2 1.91
8 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
9 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
10 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26
11 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
12 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
13 INT198904 Localization of Lrp1 11 0.62 3.25 1.01
14 INT198872 Binding of Lrp1 9 0.36 2.73 0.89
15 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82
16 INT164756 Negative_regulation of PDGFRB 32 0.57 21.69 0.72
17 INT171364 Localization of Pdgfrb 6 0.37 4.98 0.68
18 INT91172 Positive_regulation of Gene_expression of Pdgfrb 4 0.38 2.83 0.68
19 INT122061 Negative_regulation of Lrp1 5 0.30 2.47 0.66
20 INT171380 Positive_regulation of Localization of Pdgfrb 1 0.21 0.48 0.66
21 INT164196 Binding of LRP1 5 0.47 2.59 0.53
22 INT156254 Gene_expression of Six1 7 0.67 1.52 0.51
23 INT144024 Negative_regulation of Phosphorylation of Pdgfrb 6 0.42 3.48 0.51
24 INT73200 Positive_regulation of PDGFRB 10 0.67 9.67 0.48
25 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
26 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
27 INT198906 Positive_regulation of Localization of Lrp1 4 0.53 0.51 0.45
28 INT192342 Phosphorylation of PDGFRB 11 0.80 1.68 0.43
29 INT159221 Negative_regulation of TBX1 4 0.41 4.22 0.43
30 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
31 INT65606 Binding of TBX1 2 0.30 3.13 0.41
32 INT192344 Negative_regulation of Phosphorylation of PDGFRB 4 0.54 1.26 0.38
33 INT146107 Positive_regulation of Lrp1 4 0.37 1.91 0.34
34 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34
35 INT198889 Protein_catabolism of Lrp1 5 0.68 1.6 0.32
36 INT342668 Regulation of LRP1 1 0.01 0.2 0.31
37 INT127984 Positive_regulation of LRP1 5 0.69 0.74 0.3
38 INT192348 Positive_regulation of Gene_expression of PDGFRB 5 0.64 3.57 0.3
39 INT144021 Binding of Pdgfrb 9 0.37 5.53 0.28
40 INT269082 Gene_expression of TBX1 1 0.14 0.36 0.28
41 INT223078 Negative_regulation of Gene_expression of Pdgfrb 4 0.35 3.64 0.25
42 INT279296 Localization of PDGFRB 4 0.54 2.71 0.24
43 INT198873 Regulation of Lrp1 3 0.35 1.45 0.24
44 INT250836 Binding of Fgf8 3 0.35 0.66 0.24
45 INT306427 Localization of TBX1 1 0.20 1.08 0.23
46 INT306428 Positive_regulation of Localization of TBX1 1 0.14 1.08 0.23
47 INT250833 Localization of Fgf8 1 0.74 0.46 0.21
48 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21
49 INT198877 Regulation of Gene_expression of Lrp1 2 0.32 0.62 0.17
50 INT127985 Localization of LRP1 1 0.80 0.21 0.16
51 INT192339 Positive_regulation of Positive_regulation of PDGFRB 2 0.46 1.02 0.14
52 INT250835 Positive_regulation of Fgf8 1 0.50 0.42 0.14
53 INT144023 Negative_regulation of Positive_regulation of Pdgfrb 2 0.42 1.43 0.13
54 INT162568 Regulation of TBX1 3 0.35 1.54 0.11
55 INT258933 Protein_catabolism of TBX1 1 0.43 0.75 0.11
56 INT192341 Negative_regulation of Gene_expression of PDGFRB 3 0.40 0.85 0.08
57 INT223082 Regulation of Pdgfrb 3 0.25 2.14 0.08
58 INT192338 Positive_regulation of Phosphorylation of PDGFRB 4 0.45 0.48 0.07
59 INT277162 Positive_regulation of Binding of Pdgfrb 1 0.06 1.1 0.07
60 INT223616 Binding of PDGFRB 3 0.32 2.33 0.05
61 INT208924 Gene_expression of Eya1 1 0.34 0.33 0.05
62 INT192340 Regulation of PDGFRB 4 0.45 3.83 0.03
63 INT202302 Regulation of Gene_expression of Pdgfrb 1 0.22 1.03 0.03
64 INT279297 Positive_regulation of Localization of PDGFRB 1 0.36 0.5 0.03
65 INT198907 Positive_regulation of Gene_expression of Lrp1 7 0.49 3.2 0
66 INT209993 Transcription of LRP1 2 0.33 0.41 0
67 INT336195 Negative_regulation of Negative_regulation of PDGFRB 1 0.03 0.19 0
68 INT268362 Phosphorylation of LRP1 1 0.08 0.35 0
69 INT198865 Positive_regulation of Negative_regulation of Lrp1 1 0.35 0.28 0
70 INT115666 Gene_expression of LRP1 1 0.19 0.29 0
71 INT338265 Positive_regulation of Binding of PDGFRB 1 0.25 1.38 0
72 INT326611 Negative_regulation of Transcription of LRP1 1 0.21 0.41 0
73 INT328279 Positive_regulation of Regulation of PDGFRB 1 0.37 0.74 0
74 INT209991 Negative_regulation of Positive_regulation of LRP1 1 0.12 0 0
75 INT209994 Positive_regulation of Transcription of LRP1 1 0.13 0 0
76 INT209995 Negative_regulation of LRP1 1 0.12 0 0
77 INT200104 Regulation of Gene_expression of PDGFRB 1 0.18 0.29 0
78 INT213510 Localization of Eya1 1 0.65 0 0
79 INT292121 Regulation of Regulation of PDGFRB 1 0.22 0.93 0
80 INT314739 Transcription of TBX1 1 0.32 0.8 0
81 INT292128 Positive_regulation of Negative_regulation of PDGFRB 1 0.25 1.08 0
82 INT250830 Regulation of Protein_catabolism of Fgf8 1 0.45 0.08 0
83 INT311651 Positive_regulation of Fgf8 1 0.46 0.26 0
84 INT277697 Positive_regulation of Positive_regulation of Pdgfrb 1 0.06 0.49 0
85 INT213525 Regulation of Localization of Eya1 1 0.39 0 0
86 INT268391 Positive_regulation of Phosphorylation of LRP1 1 0.06 0.35 0
87 INT250846 Positive_regulation of Protein_catabolism of Fgf8 1 0.50 0.07 0
88 INT277698 Transcription of Pdgfrb 1 0.09 2.67 0
89 INT328277 Negative_regulation of Positive_regulation of PDGFRB 1 0.36 1.64 0
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