GO:0036004

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Name GAF domain binding
Categary Function
Go Slim No
Go Link GO:0036004
Unique Molecular Interactions 26
Total Molecular Interactions 32
Total Single Events 221
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for GAF domain binding. They are ordered first by their pain relevance and then by number of times they were reported for GAF domain binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08
2 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
3 INT275087 Pde2a Negative_regulation of stm 1 0.01 0.51 0.42
4 INT275104 Pde2a Negative_regulation of RTP3 1 0.00 0.51 0.42
5 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24
6 INT167040 Binding of Aip and Drb1 1 0.10 0.54 0.1
7 INT167041 Binding of HLA-A and Aip 1 0.02 0.54 0.1
8 INT257217 Binding of Pde2a and Pde5a 1 0.03 0 0.1
9 INT145987 Binding of CTLA4 and Aip 1 0.08 0.61 0.09
10 INT148096 Vasp Regulation of Pde2a 1 0.00 0.23 0.08
11 INT308432 Binding of PDE4A and Aip 1 0.05 3.1 0.05
12 INT325600 Nppa Positive_regulation of Pde2a 1 0.11 0.16 0.03
13 INT308425 Binding of Pde2a and Aip 1 0.04 1.37 0
14 INT325602 Binding of Ang and Pde2a 1 0.07 0.15 0
15 INT161823 Positive_regulation of Binding of Igha and Aip 1 0.01 0.16 0
16 INT325603 Pde2a Regulation of Rgs2 1 0.03 0 0
17 INT161822 Binding of Igha and Aip 1 0.00 0.16 0
18 INT325613 Pls1 Regulation of Pde2a 1 0.00 0 0
19 INT325593 Pde2a Positive_regulation of Negative_regulation of Nppa 1 0.11 0 0
20 INT66168 Pde2a Negative_regulation of Adra2a 1 0.04 0 0
21 INT325612 Rgs2 Regulation of Pde2a 1 0.10 0 0
22 INT325609 Pde2a Positive_regulation of Gene_expression of Rgs2 1 0.12 0 0
23 INT161825 Binding of IgG and Aip 1 0.01 0.32 0
24 INT308426 Binding of Pde4a and Aip 1 0.02 0.89 0
25 INT161824 Positive_regulation of Binding of and Aip 1 0.01 0.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for GAF domain binding. They are ordered first by their pain relevance and then by number of times they were reported in GAF domain binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT188852 Gene_expression of Pde2a 13 0.19 6.44 5.35
2 INT121801 Binding of Aip 18 0.36 24.1 5.26
3 INT112989 Gene_expression of AIP 3 0.56 25.4 4.23
4 INT148671 Gene_expression of Aip 26 0.63 24.32 3.91
5 INT120062 Binding of AIP 4 0.42 28.86 3.91
6 INT3564 Positive_regulation of Aip 11 0.58 15.38 3.62
7 INT30172 Positive_regulation of Pde2a 3 0.39 0.55 2.77
8 INT64530 Negative_regulation of Positive_regulation of Pde2a 1 0.36 0 1.81
9 INT12781 Regulation of Pde2a 4 0.23 1.14 1.69
10 INT64529 Localization of Pde2a 1 0.59 0 1.63
11 INT1580 Negative_regulation of Pde2a 7 0.52 3.26 1.59
12 INT188855 Positive_regulation of Gene_expression of Pde2a 5 0.12 1.97 1.53
13 INT14195 Localization of Pde2a 4 0.16 0.34 1.33
14 INT287798 Localization of AIP 1 0.63 5.96 1.31
15 INT114091 Negative_regulation of Aip 6 0.48 4.16 1.3
16 INT287799 Positive_regulation of Gene_expression of AIP 1 0.42 7.39 1.19
17 INT7834 Gene_expression of Pde2a 5 0.51 1.9 1.01
18 INT274238 Positive_regulation of AIP 2 0.42 8.14 0.97
19 INT188851 Regulation of Gene_expression of Pde2a 1 0.04 0.75 0.94
20 INT89776 Positive_regulation of Pde2a 2 0.47 2.84 0.81
21 INT183161 Regulation of Pde2a 2 0.05 0.5 0.67
22 INT154613 Regulation of Aip 5 0.21 3.86 0.55
23 INT154449 Positive_regulation of Gene_expression of Aip 2 0.43 2.88 0.52
24 INT144179 Localization of Aip 4 0.61 2.59 0.33
25 INT287800 Positive_regulation of Positive_regulation of AIP 1 0.42 2.15 0.3
26 INT356135 Positive_regulation of Binding of Aip 1 0.09 0.81 0.24
27 INT356136 Negative_regulation of Localization of Aip 1 0.08 0.88 0.23
28 INT167038 Binding of Aip 2 0.21 2.13 0.19
29 INT287797 Phosphorylation of AIP 1 0.78 2.04 0.16
30 INT112990 Negative_regulation of AIP 1 0.10 0.59 0.09
31 INT167037 Regulation of Aip 1 0.25 0.71 0.09
32 INT111440 Negative_regulation of Gene_expression of Pde2a 1 0.20 1.14 0.07
33 INT183439 Protein_catabolism of Pde2a 1 0.14 0.84 0.05
34 INT183425 Negative_regulation of Protein_catabolism of Pde2a 1 0.09 0.84 0.05
35 INT183433 Regulation of Localization of Pde2a 1 0.09 0.34 0.04
36 INT308415 Negative_regulation of Transcription of Aip 1 0.48 0.82 0.03
37 INT308414 Negative_regulation of Gene_expression of Aip 1 0.48 0.82 0.03
38 INT308416 Regulation of Gene_expression of Aip 1 0.37 0.77 0
39 INT183430 Binding of Pde2a 1 0.07 0 0
40 INT325558 Negative_regulation of Gene_expression of Pde2a 1 0.11 0.38 0
41 INT308417 Transcription of Aip 1 0.59 0.82 0
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