GO:0036006

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Name cellular response to macrophage colony-stimulating factor stimulus
Categary Process
Go Slim No
Go Link GO:0036006
Unique Molecular Interactions 50
Total Molecular Interactions 71
Total Single Events 286
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular response to macrophage colony-stimulating factor stimulus. They are ordered first by their pain relevance and then by number of times they were reported for cellular response to macrophage colony-stimulating factor stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14197 Pde2a Positive_regulation of Localization of Gh1 2 0.04 0 1.08
2 INT202160 Binding of ARSD and CSF1R 1 0.16 1.69 0.59
3 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
4 INT86972 PDE1B Positive_regulation of Localization of Gh 1 0.00 0 0.42
5 INT275087 Pde2a Negative_regulation of stm 1 0.01 0.51 0.42
6 INT275104 Pde2a Negative_regulation of RTP3 1 0.00 0.51 0.42
7 INT79383 Pde1b Regulation of Oprd1 1 0.02 0 0.34
8 INT177978 Binding of CSF1R and SNRNP70 1 0.02 1.49 0.28
9 INT177977 RUNX1 Regulation of CSF1R 1 0.14 1 0.27
10 INT290376 Binding of CSF1R and MEFV 1 0.29 0.31 0.24
11 INT235125 PDE2A Negative_regulation of Twist1 1 0.00 0.99 0.24
12 INT276065 Camk2a Negative_regulation of Pde1b 1 0.56 0 0.17
13 INT276060 Pde1b Regulation of Car2 1 0.30 0 0.15
14 INT273017 Binding of PDE1B and PDE11A 1 0.08 0.35 0.14
15 INT135941 Positive_regulation of PDE2A Positive_regulation of Gene_expression of PRKG1 1 0.13 0.8 0.13
16 INT276079 Pde1b Negative_regulation of Camk2a 1 0.41 0 0.12
17 INT177980 CSF1R Regulation of PXN 1 0.07 0.48 0.11
18 INT135943 Positive_regulation of PRKG1 Regulation of PDE2A 1 0.08 0.73 0.1
19 INT257217 Binding of Pde2a and Pde5a 1 0.03 0 0.1
20 INT148096 Vasp Regulation of Pde2a 1 0.00 0.23 0.08
21 INT98269 PDE2A Positive_regulation of PRKG1 1 0.07 0.57 0.08
22 INT98270 Positive_regulation of PDE2A Positive_regulation of PRKG1 1 0.07 0.57 0.08
23 INT276067 Binding of Car2 and Pde1b 1 0.32 0 0.06
24 INT276050 Binding of Calm3 and Pde1b 1 0.15 0 0.06
25 INT276049 Pde1b Regulation of Positive_regulation of Rpa1 1 0.04 0 0.06
26 INT276036 Negative_regulation of Pde1b Positive_regulation of Phosphorylation of Prkaca 1 0.27 0 0.03
27 INT325600 Nppa Positive_regulation of Pde2a 1 0.11 0.16 0.03
28 INT276055 Negative_regulation of Pde1b Positive_regulation of Prkaca 1 0.27 0 0.03
29 INT276070 Negative_regulation of Pde1b Positive_regulation of Phosphorylation of Ppp1r1b 1 0.24 0 0.03
30 INT308425 Binding of Pde2a and Aip 1 0.04 1.37 0
31 INT325602 Binding of Ang and Pde2a 1 0.07 0.15 0
32 INT276044 Binding of Pde1b and Ppp1cc 1 0.12 0 0
33 INT276048 Binding of Pde1b and Myoz1 1 0.04 0 0
34 INT186239 Binding of ROS1 and Positive_regulation of PDE2A 1 0.00 0 0
35 INT276078 Binding of Camk2a and Pde1b 1 0.36 0 0
36 INT263182 Ca2 Positive_regulation of Phosphorylation of Pde1b 1 0.01 0 0
37 INT276052 Negative_regulation of Pde1b Negative_regulation of Camk2a 1 0.41 0 0
38 INT186241 Gene_expression of ROS1 Positive_regulation of PDE2A 1 0.00 0 0
39 INT325603 Pde2a Regulation of Rgs2 1 0.03 0 0
40 INT325613 Pls1 Regulation of Pde2a 1 0.00 0 0
41 INT276058 Camk2a Regulation of Pde1b 1 0.26 0 0
42 INT325593 Pde2a Positive_regulation of Negative_regulation of Nppa 1 0.11 0 0
43 INT66168 Pde2a Negative_regulation of Adra2a 1 0.04 0 0
44 INT263183 Binding of Pde1b and Pde5a 1 0.03 0 0
45 INT276042 Negative_regulation of Binding of Calm3 and Pde1b 1 0.17 0 0
46 INT325612 Rgs2 Regulation of Pde2a 1 0.10 0 0
47 INT325609 Pde2a Positive_regulation of Gene_expression of Rgs2 1 0.12 0 0
48 INT276047 Camk2a Regulation of Negative_regulation of Pde1b 1 0.43 0 0
49 INT276051 Pde1b Regulation of Regulation of Car2 1 0.30 0 0
50 INT276071 Pde1b Regulation of Positive_regulation of Camk2a 1 0.43 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular response to macrophage colony-stimulating factor stimulus. They are ordered first by their pain relevance and then by number of times they were reported in cellular response to macrophage colony-stimulating factor stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT152433 Binding of CSF1R 6 0.33 10.97 5.54
2 INT188852 Gene_expression of Pde2a 13 0.19 6.44 5.35
3 INT152254 Gene_expression of CSF1R 16 0.75 12.93 3.81
4 INT75815 Positive_regulation of PDE2A 10 0.40 5.1 3.15
5 INT177993 Localization of CSF1R 4 0.73 7.49 2.94
6 INT19235 Negative_regulation of PDE1B 11 0.14 2.38 2.81
7 INT30172 Positive_regulation of Pde2a 3 0.39 0.55 2.77
8 INT178002 Positive_regulation of CSF1R 2 0.37 6.52 2.74
9 INT64530 Negative_regulation of Positive_regulation of Pde2a 1 0.36 0 1.81
10 INT12781 Regulation of Pde2a 4 0.23 1.14 1.69
11 INT64529 Localization of Pde2a 1 0.59 0 1.63
12 INT1580 Negative_regulation of Pde2a 7 0.52 3.26 1.59
13 INT188855 Positive_regulation of Gene_expression of Pde2a 5 0.12 1.97 1.53
14 INT68451 Localization of Pde1b 4 0.22 0 1.35
15 INT14195 Localization of Pde2a 4 0.16 0.34 1.33
16 INT73011 Gene_expression of Pde1b 3 0.23 0.38 1.27
17 INT202161 Negative_regulation of CSF1R 3 0.31 3.36 1.22
18 INT110400 Negative_regulation of Pde1b 21 0.50 0.58 1.14
19 INT110394 Regulation of CSF1R 3 0.38 2.49 1.12
20 INT7834 Gene_expression of Pde2a 5 0.51 1.9 1.01
21 INT69302 Positive_regulation of Pde1b 3 0.21 0.99 0.97
22 INT188851 Regulation of Gene_expression of Pde2a 1 0.04 0.75 0.94
23 INT89776 Positive_regulation of Pde2a 2 0.47 2.84 0.81
24 INT98275 Negative_regulation of PDE2A 4 0.17 3.96 0.79
25 INT183161 Regulation of Pde2a 2 0.05 0.5 0.67
26 INT202163 Negative_regulation of Localization of CSF1R 1 0.31 1.76 0.63
27 INT86971 Localization of PDE1B 4 0.15 0.08 0.6
28 INT75814 Regulation of Positive_regulation of PDE2A 1 0.23 0.26 0.56
29 INT178000 Positive_regulation of Gene_expression of CSF1R 1 0.46 0.85 0.46
30 INT162903 Localization of PDE2A 2 0.61 0.89 0.45
31 INT216759 Binding of PDE2A 1 0.00 0.08 0.44
32 INT86970 Positive_regulation of Localization of PDE1B 1 0.00 0 0.42
33 INT290389 Positive_regulation of Binding of CSF1R 1 0.25 1.14 0.4
34 INT79379 Regulation of Pde1b 1 0.07 0 0.37
35 INT235122 Negative_regulation of Positive_regulation of PDE2A 1 0.01 0.72 0.35
36 INT235113 Positive_regulation of Negative_regulation of PDE2A 1 0.01 0.72 0.35
37 INT135945 Positive_regulation of Positive_regulation of PDE2A 2 0.12 0.78 0.34
38 INT242948 Gene_expression of PDE1B 1 0.02 0.91 0.34
39 INT177994 Negative_regulation of Phosphorylation of CSF1R 1 0.39 1 0.34
40 INT177999 Phosphorylation of CSF1R 1 0.75 0.99 0.33
41 INT276012 Gene_expression of Pde1b 8 0.66 0.58 0.32
42 INT276027 Positive_regulation of Pde1b 7 0.59 0.71 0.32
43 INT290388 Regulation of Gene_expression of CSF1R 1 0.24 0.84 0.25
44 INT100251 Regulation of PDE1B 4 0.26 1.21 0.22
45 INT98276 Regulation of PDE2A 2 0.07 1.54 0.17
46 INT242946 Positive_regulation of Phosphorylation of PDE1B 1 0.01 0.22 0.17
47 INT275085 Transcription of PDE1B 1 0.04 0.27 0.16
48 INT84749 Gene_expression of PDE2A 3 0.73 0.84 0.12
49 INT135946 Positive_regulation of Gene_expression of PDE2A 1 0.12 0.77 0.12
50 INT179449 Binding of PDE1B 5 0.07 0.3 0.11
51 INT135944 Regulation of Regulation of PDE2A 1 0.07 0.73 0.1
52 INT80630 Protein_catabolism of PDE2A 2 0.19 0.91 0.08
53 INT242947 Phosphorylation of PDE1B 1 0.02 0.11 0.08
54 INT100247 Positive_regulation of PDE1B 2 0.40 0.65 0.07
55 INT111440 Negative_regulation of Gene_expression of Pde2a 1 0.20 1.14 0.07
56 INT276000 Negative_regulation of Positive_regulation of Pde1b 2 0.36 0.54 0.06
57 INT275994 Positive_regulation of Negative_regulation of Pde1b 1 0.43 0 0.06
58 INT183439 Protein_catabolism of Pde2a 1 0.14 0.84 0.05
59 INT183425 Negative_regulation of Protein_catabolism of Pde2a 1 0.09 0.84 0.05
60 INT183433 Regulation of Localization of Pde2a 1 0.09 0.34 0.04
61 INT19234 Positive_regulation of Negative_regulation of PDE1B 1 0.01 0.05 0.04
62 INT275993 Negative_regulation of Gene_expression of Pde1b 2 0.36 0.53 0.03
63 INT276029 Regulation of Negative_regulation of Pde1b 1 0.38 0 0.03
64 INT275998 Positive_regulation of Gene_expression of Pde1b 1 0.43 0 0.03
65 INT100252 Regulation of Regulation of PDE1B 1 0.26 0.55 0
66 INT162918 Transcription of PDE2A 1 0.65 0 0
67 INT276008 Negative_regulation of Localization of Pde1b 1 0.36 0 0
68 INT276007 Negative_regulation of Phosphorylation of Pde1b 1 0.36 0 0
69 INT276001 Positive_regulation of Phosphorylation of Pde1b 1 0.40 0 0
70 INT162902 Positive_regulation of Protein_catabolism of PDE1B 1 0.11 0 0
71 INT162914 Regulation of Localization of PDE2A 1 0.37 0 0
72 INT276006 Phosphorylation of Pde1b 1 0.70 0 0
73 INT275991 Regulation of Phosphorylation of Pde1b 1 0.38 0 0
74 INT162908 Protein_catabolism of PDE1B 1 0.19 0 0
75 INT276011 Localization of Pde1b 1 0.64 0 0
76 INT162916 Negative_regulation of Transcription of PDE2A 1 0.40 0 0
77 INT276023 Positive_regulation of Positive_regulation of Pde1b 1 0.43 0 0
78 INT183430 Binding of Pde2a 1 0.07 0 0
79 INT275999 Binding of Pde1b 1 0.32 0 0
80 INT325558 Negative_regulation of Gene_expression of Pde2a 1 0.11 0.38 0
81 INT263186 Phosphorylation of Pde1b 1 0.24 0 0
82 INT80629 Negative_regulation of Protein_catabolism of PDE2A 1 0.12 0.18 0
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