GO:0038001

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Name paracrine signaling
Categary Process
Go Slim No
Go Link GO:0038001
Unique Molecular Interactions 53
Total Molecular Interactions 62
Total Single Events 825
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for paracrine signaling. They are ordered first by their pain relevance and then by number of times they were reported for paracrine signaling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
2 INT225021 PDGFB Positive_regulation of Ccl21 1 0.10 0.07 0.3
3 INT225026 PDGFB Positive_regulation of Gene_expression of Ccl21 1 0.10 0.07 0.3
4 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29
5 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29
6 INT355734 Pdgfb Regulation of Bdnf 1 0.22 1.5 0.27
7 INT355733 Pdgfb Regulation of Transcription of Bdnf 1 0.10 0.86 0.19
8 INT355732 Pdgfb Negative_regulation of Bdnf 1 0.13 0.87 0.17
9 INT202312 PDGFB Positive_regulation of Gene_expression of Col7a1 1 0.01 0.7 0.16
10 INT202311 PDGFB Positive_regulation of Gene_expression of Fn1 1 0.02 0.7 0.16
11 INT139538 Binding of CD34 and KIT 2 0.39 2.73 0.14
12 INT95103 TGFBR2 Positive_regulation of CD34 1 0.11 0.61 0.14
13 INT223084 Binding of Pdgfa and Pdgfb 2 0.17 0.83 0.13
14 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
15 INT225024 PDGFB Positive_regulation of Gene_expression of Cxcl5 1 0.16 0.08 0.13
16 INT277986 Negative_regulation of Epo Positive_regulation of Localization of Cd34 1 0.08 0.77 0.12
17 INT263429 Pdgfb Positive_regulation of Localization of Abl1 1 0.01 0 0.12
18 INT118052 Binding of Pecam1 and Cd34 1 0.22 0.51 0.1
19 INT48194 Pdgfb Positive_regulation of Setd1a 1 0.23 0 0.09
20 INT299953 Binding of CD34 and FTSJ3 1 0.04 1.07 0.09
21 INT223085 Binding of Pdgfb and Insrr 1 0.01 0.91 0.07
22 INT279280 Binding of PDGFA and PDGFB 1 0.06 0.9 0.06
23 INT343477 Epo Positive_regulation of Pdgfb 1 0.11 0.31 0.06
24 INT225023 PDGFB Regulation of Transcription of Ccl21 1 0.11 0 0.06
25 INT94852 PDGFB Regulation of Gene_expression of COL7A1 1 0.09 0.06 0.06
26 INT209615 Binding of KRT20 and Cd34 1 0.00 1.05 0.06
27 INT225022 PDGFB Regulation of Ccl21 1 0.11 0 0.06
28 INT343471 Epo Positive_regulation of Gene_expression of Pdgfb 1 0.11 0.31 0.06
29 INT209611 Binding of Mme and Cd34 1 0.00 1.05 0.06
30 INT118227 Binding of ACTG2 and CD34 1 0.15 1.17 0.06
31 INT209610 Binding of Cd22 and Cd34 1 0.01 1.05 0.06
32 INT202310 Binding of PDGFB and Pdgfrb 1 0.11 0.39 0.04
33 INT263427 Pdgfb Positive_regulation of Phosphorylation of Rock1 1 0.00 0 0.04
34 INT223086 Binding of Pdgfb and Pdgfrb 1 0.33 0.46 0.04
35 INT279288 PDGFB Positive_regulation of NCOR2 1 0.00 0.52 0.03
36 INT279285 PDGFB Positive_regulation of TXK 1 0.05 0.52 0.03
37 INT313618 Binding of Acly and Pdgfb 1 0.00 0.18 0.03
38 INT328408 Nlrp1a Positive_regulation of Pdgfb 1 0.07 0.74 0.03
39 INT279277 PDGFB Positive_regulation of PDGFRB 1 0.14 0.52 0.03
40 INT308314 Binding of CD34 and Pfpl 1 0.03 0.57 0
41 INT249850 Binding of Ptprc and Cd34 1 0.13 0.48 0
42 INT347035 Binding of Kit and Cd34 1 0.02 1.38 0
43 INT328411 Nlrp1a Negative_regulation of Pdgfb 1 0.08 0.39 0
44 INT224993 INCENP Regulation of PDGFB 1 0.00 0 0
45 INT223083 Gene_expression of Pdgfb Positive_regulation of Cm3 1 0.02 1 0
46 INT225020 Binding of PDGFB and Mtpn 1 0.01 0.15 0
47 INT277703 Binding of Pdgfrb and Pdgfb 1 0.02 0.23 0
48 INT213744 Binding of Cd34 and Epc1 1 0.12 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for paracrine signaling. They are ordered first by their pain relevance and then by number of times they were reported in paracrine signaling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39
2 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97
3 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
4 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
5 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14
6 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
7 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
8 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28
9 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19
10 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
11 INT74528 Negative_regulation of PDGFB 11 0.40 10.34 1.48
12 INT21682 Binding of CD34 18 0.47 13.19 1.47
13 INT74530 Transcription of PDGFB 7 0.65 4.56 1.47
14 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36
15 INT192349 Negative_regulation of Gene_expression of PDGFB 5 0.31 2.64 1.25
16 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17
17 INT119168 Negative_regulation of Cd34 8 0.37 4.91 0.96
18 INT126967 Localization of Cd34 9 0.79 3.69 0.87
19 INT96188 Binding of Cd34 11 0.31 10.4 0.82
20 INT202307 Regulation of Gene_expression of PDGFB 2 0.26 1.24 0.71
21 INT74529 Binding of PDGFB 13 0.36 7.41 0.62
22 INT277699 Gene_expression of Pdgfb 5 0.20 4.84 0.59
23 INT94713 Regulation of CD34 11 0.45 8.02 0.58
24 INT128472 Negative_regulation of CD34 7 0.42 3.92 0.58
25 INT202306 Negative_regulation of Localization of PDGFB 2 0.25 0.76 0.55
26 INT196003 Regulation of Cd34 4 0.30 3.38 0.5
27 INT202309 Regulation of Localization of PDGFB 1 0.36 0.92 0.49
28 INT87819 Localization of CD34 21 0.81 7.69 0.47
29 INT223081 Negative_regulation of Gene_expression of Pdgfb 2 0.37 3.07 0.47
30 INT313617 Positive_regulation of Pdgfb 4 0.35 1.53 0.46
31 INT119251 Positive_regulation of Gene_expression of CD34 12 0.49 5.2 0.44
32 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42
33 INT76143 Positive_regulation of Regulation of PDGFB 1 0.01 0.08 0.4
34 INT74532 Positive_regulation of Transcription of PDGFB 1 0.57 0.73 0.4
35 INT317875 Binding of Pdgfb 3 0.10 1.15 0.36
36 INT153261 Positive_regulation of Localization of PDGFB 2 0.37 1.98 0.36
37 INT232153 Regulation of Negative_regulation of Cd34 1 0.05 0.07 0.35
38 INT224441 Negative_regulation of Pdgfb 2 0.33 1.61 0.27
39 INT232504 Negative_regulation of Gene_expression of CD34 4 0.38 1.89 0.23
40 INT349702 Positive_regulation of Transcription of Pdgfb 1 0.35 0 0.23
41 INT277701 Localization of Pdgfb 3 0.23 1.49 0.22
42 INT349701 Transcription of Pdgfb 1 0.40 0 0.22
43 INT135706 Negative_regulation of Binding of CD34 1 0.40 1.19 0.16
44 INT137457 Positive_regulation of Localization of Cd34 1 0.46 0.55 0.16
45 INT232508 Regulation of Gene_expression of CD34 4 0.43 2.73 0.13
46 INT225004 Regulation of Positive_regulation of PDGFB 1 0.26 0.1 0.13
47 INT319408 Negative_regulation of Binding of PDGFB 1 0.15 0.89 0.09
48 INT355724 Negative_regulation of Positive_regulation of Pdgfb 1 0.13 0.6 0.07
49 INT319411 Negative_regulation of Transcription of PDGFB 1 0.15 1.03 0.07
50 INT308300 Positive_regulation of Localization of CD34 3 0.44 1.82 0.05
51 INT277702 Positive_regulation of Gene_expression of Pdgfb 2 0.10 0.55 0.05
52 INT229654 Positive_regulation of Gene_expression of Cd34 2 0.45 1.19 0.05
53 INT221855 Regulation of Positive_regulation of CD34 1 0.31 0.83 0.04
54 INT225003 Positive_regulation of Binding of PDGFB 1 0.29 0 0.03
55 INT202308 Phosphorylation of PDGFB 1 0.34 0.43 0.03
56 INT223077 Regulation of Pdgfb 1 0.23 0.34 0
57 INT343453 Phosphorylation of Pdgfb 1 0.13 0.1 0
58 INT277700 Binding of Pdgfb 1 0.09 0.67 0
59 INT320552 Transcription of CD34 1 0.67 1.23 0
60 INT277696 Regulation of Positive_regulation of Pdgfb 1 0.03 0.52 0
61 INT308295 Positive_regulation of Positive_regulation of CD34 1 0.60 0.44 0
62 INT223079 Regulation of Gene_expression of Pdgfb 1 0.23 1.17 0
63 INT294258 Phosphorylation of CD34 1 0.69 0.06 0
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