GO:0040011

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Name locomotion
Categary Process
Go Slim Yes
Go Link GO:0040011
Unique Molecular Interactions 120
Total Molecular Interactions 175
Total Single Events 1510
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for locomotion. They are ordered first by their pain relevance and then by number of times they were reported for locomotion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
2 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
3 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
4 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
5 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
6 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
7 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
8 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
9 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
10 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
11 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
12 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
13 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
14 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
15 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
16 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
17 INT108647 Binding of Grin2a and Camk1d 1 0.33 0.78 0.9
18 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
19 INT152857 PRS Regulation of Nefl 1 0.00 0.19 0.77
20 INT152833 Nefl Regulation of Prkcg 1 0.12 0.19 0.77
21 INT152834 Nefl Regulation of Nefh 1 0.10 0.19 0.77
22 INT296292 Binding of Car1 and Grin2a 1 0.14 0.32 0.72
23 INT296289 Grin2a Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
24 INT296288 Grin2a Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
25 INT112107 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2a 1 0.40 0.49 0.57
26 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
27 INT112106 Negative_regulation of Dlg2 Negative_regulation of Grin2a 1 0.40 0.48 0.56
28 INT311524 Gnrhr Positive_regulation of Transcription of Grin2a 1 0.02 0.54 0.55
29 INT251151 Binding of Grin2a and Dlg3 1 0.24 0.32 0.54
30 INT208121 Binding of Grin2a and Grin2b 3 0.35 0.06 0.51
31 INT208122 Grin2a Positive_regulation of Positive_regulation of Ltp 1 0.16 0.21 0.49
32 INT250081 Grin2a Positive_regulation of Ltp 1 0.20 0.14 0.48
33 INT208120 Binding of Grin2a and Hpcal1 1 0.10 0.07 0.48
34 INT127394 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin2a 1 0.01 0.71 0.45
35 INT127396 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin2a 1 0.00 0.71 0.45
36 INT229507 Binding of Nefl and Ndel1 1 0.09 2.01 0.43
37 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
38 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 0.22 0.09 0.41
39 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4
40 INT296301 Binding of Grin2a and Kcnip3 1 0.27 0 0.4
41 INT250076 Grin2a Regulation of Positive_regulation of Ltp 1 0.10 0.06 0.35
42 INT251148 Negative_regulation of Binding of Grin2a and Dlg2 1 0.37 0.45 0.32
43 INT213485 Lep Positive_regulation of Localization of Grin2a 1 0.19 0 0.31
44 INT212289 Vsnl1 Negative_regulation of Grin2a 1 0.04 0.38 0.28
45 INT263732 Binding of Grin2a and Neto1 1 0.41 0 0.27
46 INT317510 Binding of Grin2a and Gnptab 1 0.00 0 0.26
47 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
48 INT250075 Binding of Hpcal4 and Negative_regulation of Gene_expression of Grin2a 1 0.03 0 0.24
49 INT311527 Binding of Grin2a and Gria1 1 0.01 0 0.21
50 INT311526 Gria1 Regulation of Gene_expression of Grin2a 1 0.01 0.32 0.15
51 INT94763 PSEN2 Regulation of Positive_regulation of App 1 0.11 0.72 0.14
52 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
53 INT229504 Negative_regulation of Binding of Nefl and Ndel1 1 0.08 0.33 0.09
54 INT229512 Binding of Nefl and Gopc 1 0.01 0.35 0.09
55 INT229495 Negative_regulation of Binding of Nefl and Gopc 1 0.02 0.35 0.09
56 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
57 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
58 INT229501 Binding of Nefl and Vim 1 0.05 0.32 0.08
59 INT263782 Grin2a Regulation of Localization of Grin1 1 0.29 0.17 0.07
60 INT263764 Dlg4 Regulation of Localization of Grin2a 1 0.16 0.17 0.07
61 INT263777 Grin2a Regulation of Localization of Vamp2 1 0.26 0.17 0.07
62 INT263759 Grin1 Regulation of Localization of Grin2a 1 0.29 0.17 0.07
63 INT263772 Grin2a Regulation of Localization of Gria2 1 0.19 0.17 0.07
64 INT263771 Grin2a Regulation of Localization of Dlg4 1 0.19 0.17 0.07
65 INT263762 Grin2a Regulation of Localization of Grin2b 1 0.26 0.17 0.07
66 INT243256 Binding of Nefl and Cfp 1 0.24 0.6 0.07
67 INT243258 Binding of Calb2 and Nefl 1 0.17 0.61 0.07
68 INT263768 Grin2b Regulation of Localization of Grin2a 1 0.26 0.17 0.07
69 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
70 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
71 INT250073 Grin2a Regulation of Grin2b 1 0.39 0.9 0.05
72 INT263730 Binding of Grin2a and Rasgrf1 1 0.23 0 0.05
73 INT263780 Localization of Neto1 Regulation of Localization of Grin2a 1 0.38 0.18 0.05
74 INT193967 Binding of PSEN1 and Psen1 1 0.41 1.2 0.05
75 INT193970 Binding of PSEN1 and Psen2 1 0.36 2.06 0.05
76 INT356101 App Regulation of Negative_regulation of Psen1 1 0.23 0.31 0.04
77 INT331477 PSEN2 Regulation of Gene_expression of Psen1 1 0.00 0.15 0.03
78 INT354896 Binding of Psen2 and Fancd2 1 0.04 0.75 0.03
79 INT331478 Psen1 Regulation of Gene_expression of PSEN2 1 0.00 0.15 0.03
80 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
81 INT326979 HLN2 Negative_regulation of JPH3 1 0.02 2.05 0
82 INT193962 Binding of Psen1 and Ncstn 1 0.13 0.08 0
83 INT229511 Ndel1 Regulation of Binding of Nefl 1 0.09 0.31 0
84 INT334644 Binding of PSEN1 and TTN 1 0.01 0 0
85 INT225969 Binding of Aqp4 and Nefl 1 0.07 0.3 0
86 INT350098 Gene_expression of PSEN2 Positive_regulation of Gene_expression of Hmox1 1 0.39 0 0
87 INT273289 Binding of Psen2 and Ryr2 1 0.27 4.53 0
88 INT217398 Binding of Psen2 and Bace1 1 0.12 1.44 0
89 INT240723 Atp2b2 Positive_regulation of Localization of Ca2 1 0.11 0.43 0
90 INT263766 Grin2a Positive_regulation of Negative_regulation of Neto1 1 0.42 0 0
91 INT193955 Binding of Psen1 and Psen2 1 0.37 1.64 0
92 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
93 INT286331 Binding of Psen1 and Ror1 1 0.27 0 0
94 INT326980 HSD11B1 Negative_regulation of JPH3 1 0.03 2.05 0
95 INT193968 Binding of PSEN1 and Ps 1 0.07 0.66 0
96 INT262712 Psen1 Regulation of Gene_expression of Bace1 1 0.22 0.07 0
97 INT240724 Atp2b2 Positive_regulation of Ca2 1 0.11 0.54 0
98 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0
99 INT286337 PSENEN Regulation of Psen1 1 0.07 0.37 0
100 INT193958 Binding of Pld1 and Psen1 1 0.17 0 0
101 INT193953 Binding of Bcl2l1 and Psen1 1 0.07 0.66 0
102 INT193956 Binding of Psen1 and Rab6a 1 0.15 0 0
103 INT294428 PSEN2 Regulation of Gene_expression of Tp53 1 0.49 0.86 0
104 INT294429 PSEN2 Negative_regulation of Tp53 1 0.46 1.03 0
105 INT193957 Binding of Bcl2l1 and Psen2 1 0.07 0.66 0
106 INT331479 Binding of PSEN2 and Psen1 1 0.00 0.07 0
107 INT234221 Negative_regulation of PSEN1 Negative_regulation of Gene_expression of APP 1 0.33 0.32 0
108 INT334645 Binding of PSEN1 and HM13 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for locomotion. They are ordered first by their pain relevance and then by number of times they were reported in locomotion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
2 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37
3 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
4 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
5 INT14647 Positive_regulation of Grin2a 26 0.67 4.69 14.8
6 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
7 INT100799 Negative_regulation of Grin2a 27 0.57 7.33 12.2
8 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
9 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
10 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
11 INT64193 Regulation of Grin2a 19 0.54 2.98 10.31
12 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
13 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
14 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41
15 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
16 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
17 INT67693 Binding of Grin2a 9 0.38 1.74 5.68
18 INT208108 Localization of Grin2a 19 0.70 1.5 5.22
19 INT19549 Binding of Grin2a 12 0.45 1.24 5.09
20 INT135474 Negative_regulation of Gene_expression of Grin2a 7 0.39 6.94 4.89
21 INT111947 Positive_regulation of Gene_expression of Grin2a 7 0.68 1.75 4.84
22 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
23 INT61118 Gene_expression of Nefl 11 0.75 4.02 4.02
24 INT103999 Positive_regulation of Phosphorylation of Grin2a 5 0.38 3.12 3.94
25 INT121986 Phosphorylation of Grin2a 5 0.76 0.83 3.71
26 INT209221 Regulation of Gene_expression of Grin2a 5 0.24 2.81 3.45
27 INT69990 Negative_regulation of Nefl 11 0.59 2.82 3.38
28 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
29 INT108728 Regulation of ATP1A2 4 0.45 3.65 3.04
30 INT186507 Localization of ATP1A2 2 0.74 3.35 3.04
31 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
32 INT90611 Positive_regulation of Positive_regulation of Grin2a 4 0.63 1.89 3
33 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
34 INT105730 Localization of Grin2a 7 0.67 0.64 2.56
35 INT89137 Negative_regulation of Nefl 4 0.55 0.71 2.48
36 INT141075 Transcription of Grin2a 5 0.49 1.89 2.46
37 INT163544 Binding of Psen1 40 0.36 15.28 2.42
38 INT114011 Negative_regulation of ATP1A2 5 0.45 6.12 2.41
39 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
40 INT60723 Localization of Psen2 5 0.68 2.11 2.02
41 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
42 INT74595 Regulation of Transcription of Grin2a 2 0.42 0.66 1.92
43 INT103624 Negative_regulation of Gene_expression of Grin2a 5 0.56 1.58 1.9
44 INT151174 Negative_regulation of Transcription of Grin2a 3 0.40 0 1.8
45 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
46 INT103959 Gene_expression of ATP1A2 3 0.67 2.47 1.68
47 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
48 INT114013 Binding of ATP1A2 3 0.47 3.51 1.46
49 INT78646 Regulation of Psen2 4 0.20 1.78 1.42
50 INT118581 Positive_regulation of ATP1A2 3 0.21 1.81 1.4
51 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
52 INT105729 Negative_regulation of Localization of Grin2a 3 0.38 0.08 1.29
53 INT139647 Positive_regulation of Positive_regulation of Grin2a 2 0.44 0.38 1.11
54 INT78645 Negative_regulation of Gene_expression of Psen2 1 0.14 0.13 1.01
55 INT19550 Positive_regulation of Binding of Grin2a 1 0.04 0 0.94
56 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
57 INT152841 Positive_regulation of Nefl 2 0.28 0.38 0.92
58 INT141076 Negative_regulation of Transcription of Grin2a 2 0.40 0.82 0.92
59 INT30885 Positive_regulation of Nefl 6 0.36 6.99 0.9
60 INT263688 Negative_regulation of Localization of Grin2a 2 0.31 0.16 0.84
61 INT78647 Positive_regulation of Localization of Psen2 1 0.16 0.14 0.83
62 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
63 INT94756 Positive_regulation of PSEN2 8 0.49 4.59 0.77
64 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
65 INT193849 Positive_regulation of Gene_expression of Psen2 5 0.44 4.92 0.76
66 INT78649 Binding of Psen2 7 0.36 5.9 0.73
67 INT78648 Regulation of Binding of Psen2 1 0.14 0.2 0.73
68 INT69989 Negative_regulation of Gene_expression of Nefl 2 0.43 0.44 0.67
69 INT139649 Positive_regulation of Negative_regulation of Grin2a 2 0.44 0.63 0.65
70 INT22714 Binding of Nefl 1 0.32 0 0.64
71 INT91765 Positive_regulation of Gene_expression of PSEN2 8 0.49 4.57 0.63
72 INT296254 Regulation of Phosphorylation of Grin2a 1 0.32 0.14 0.58
73 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
74 INT156379 Regulation of Binding of Grin2a 1 0.36 0.17 0.52
75 INT194335 Gene_expression of Nefl 15 0.51 5.64 0.51
76 INT271628 Negative_regulation of Regulation of Grin2a 2 0.28 1.05 0.47
77 INT250060 Positive_regulation of Localization of Grin2a 1 0.42 0 0.47
78 INT53282 Negative_regulation of Atp2b2 4 0.15 2.6 0.45
79 INT316041 Transcription of Psen2 1 0.64 1.1 0.45
80 INT250446 Positive_regulation of Localization of Grin2a 2 0.37 0 0.44
81 INT234249 Regulation of PSEN1 6 0.37 2.21 0.43
82 INT234257 Regulation of Gene_expression of PSEN1 6 0.44 1.98 0.42
83 INT193856 Localization of Psen1 19 0.73 9.79 0.41
84 INT271627 Regulation of Positive_regulation of Grin2a 1 0.30 0.23 0.4
85 INT36396 Positive_regulation of Psen2 6 0.44 4.57 0.39
86 INT177773 Localization of PSEN1 4 0.73 0.89 0.36
87 INT249529 Regulation of Phosphorylation of Grin2a 1 0.21 0.16 0.34
88 INT263687 Regulation of Localization of Grin2a 2 0.29 0 0.33
89 INT261682 Positive_regulation of Positive_regulation of PSEN2 1 0.21 0.55 0.33
90 INT224298 Negative_regulation of PSEN2 6 0.57 2.29 0.28
91 INT86055 Transcription of Nefl 1 0.12 0.09 0.28
92 INT213473 Regulation of Positive_regulation of Grin2a 1 0.16 0.05 0.28
93 INT140122 Transcription of Nefl 3 0.62 0.16 0.27
94 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27
95 INT311509 Regulation of Transcription of Grin2a 1 0.13 0.42 0.27
96 INT261676 Negative_regulation of Positive_regulation of PSEN1 1 0.36 1.59 0.25
97 INT172525 Localization of PSEN2 5 0.73 4.17 0.24
98 INT212295 Regulation of Negative_regulation of Grin2a 1 0.39 0.28 0.24
99 INT108279 Positive_regulation of Binding of Grin2a 1 0.41 0 0.23
100 INT139651 Negative_regulation of Negative_regulation of Grin2a 1 0.38 0.05 0.21
101 INT181508 Regulation of Regulation of Psen1 2 0.33 0.51 0.2
102 INT208113 Regulation of Negative_regulation of Grin2a 1 0.42 0 0.19
103 INT286317 Positive_regulation of Transcription of Psen1 1 0.37 0.32 0.17
104 INT229457 Binding of Nefl 1 0.07 0.98 0.15
105 INT114012 Negative_regulation of Binding of ATP1A2 1 0.45 1.01 0.14
106 INT336359 Positive_regulation of Phosphorylation of Psen1 1 0.33 0.4 0.13
107 INT336361 Phosphorylation of Psen1 1 0.54 0.34 0.13
108 INT176595 Negative_regulation of Gene_expression of PSEN2 1 0.24 1.01 0.11
109 INT193841 Regulation of Gene_expression of Psen2 1 0.40 1.66 0.11
110 INT201694 Negative_regulation of Gene_expression of PSEN1 3 0.41 2.31 0.1
111 INT240716 Negative_regulation of Gene_expression of Atp2b2 1 0.09 0.78 0.1
112 INT273285 Negative_regulation of Localization of Psen1 1 0.36 0.99 0.09
113 INT240713 Gene_expression of Atp2b2 1 0.14 1.16 0.09
114 INT109131 Regulation of PSEN2 3 0.44 0.55 0.08
115 INT63111 Gene_expression of JPH3 3 0.65 3.29 0.08
116 INT193862 Positive_regulation of Positive_regulation of Psen1 3 0.49 0.9 0.08
117 INT193872 Positive_regulation of Localization of Psen1 3 0.49 1.39 0.08
118 INT140120 Positive_regulation of Transcription of Nefl 1 0.43 0.09 0.08
119 INT261678 Positive_regulation of Positive_regulation of PSEN1 1 0.42 0.62 0.08
120 INT240714 Negative_regulation of Localization of Atp2b2 1 0.09 1.3 0.08
121 INT193890 Regulation of Positive_regulation of Psen1 1 0.44 0.66 0.08
122 INT193938 Phosphorylation of PSEN1 5 0.79 1.6 0.07
123 INT229474 Positive_regulation of Gene_expression of Nefl 1 0.09 0.32 0.07
124 INT229477 Negative_regulation of Gene_expression of Nefl 1 0.08 0.32 0.07
125 INT229453 Positive_regulation of Positive_regulation of Nefl 1 0.08 0.22 0.06
126 INT176592 Transcription of PSEN2 5 0.33 0.41 0.05
127 INT193859 Negative_regulation of Binding of Psen1 3 0.42 1.85 0.05
128 INT331406 Negative_regulation of Regulation of Psen1 1 0.04 0.09 0.05
129 INT193865 Protein_catabolism of Psen1 10 0.97 0.37 0.04
130 INT240715 Localization of Atp2b2 1 0.16 1.07 0.04
131 INT288855 Positive_regulation of JPH3 2 0.22 2.92 0.03
132 INT243236 Localization of Nefl 3 0.73 1.57 0
133 INT224302 Negative_regulation of Transcription of PSEN2 3 0.26 0.08 0
134 INT265229 Binding of PSEN2 2 0.16 1.37 0
135 INT326992 Phosphorylation of JPH3 1 0.16 2.15 0
136 INT286327 Regulation of Binding of Psen1 1 0.33 0.16 0
137 INT234250 Positive_regulation of Negative_regulation of PSEN1 1 0.41 0 0
138 INT193886 Regulation of Protein_catabolism of Psen1 1 0.44 0.06 0
139 INT193934 Positive_regulation of Binding of PSEN1 1 0.49 0.92 0
140 INT224297 Regulation of Transcription of PSEN2 1 0.20 0.06 0
141 INT331407 Negative_regulation of Transcription of Psen1 1 0.04 0.08 0
142 INT326074 Positive_regulation of Gene_expression of JPH3 1 0.24 0.5 0
143 INT177774 Transcription of PSEN1 1 0.33 0.09 0
144 INT326990 Binding of JPH3 1 0.07 1.95 0
145 INT326995 Localization of JPH3 1 0.15 1.82 0
146 INT263684 Regulation of Regulation of Grin2a 1 0.29 0 0
147 INT354892 Negative_regulation of Psen2 1 0.37 0.95 0
148 INT193844 Positive_regulation of Protein_catabolism of Psen1 1 0.49 0.05 0
149 INT243249 Regulation of Nefl 1 0.18 3.85 0
150 INT326994 Regulation of JPH3 1 0.05 2.28 0
151 INT331463 Regulation of Gene_expression of PSEN2 1 0.04 0 0
152 INT234258 Negative_regulation of Phosphorylation of PSEN1 1 0.35 0.49 0
153 INT155518 Negative_regulation of Phosphorylation of Grin2a 1 0.31 0.05 0
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