GO:0040016

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Name embryonic cleavage
Categary Process
Go Slim No
Go Link GO:0040016
Unique Molecular Interactions 60
Total Molecular Interactions 73
Total Single Events 291
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for embryonic cleavage. They are ordered first by their pain relevance and then by number of times they were reported for embryonic cleavage. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
2 INT121725 Binding of Trpv1 and Pik3cb 1 0.35 0.62 1.15
3 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14
4 INT121728 Ngf Positive_regulation of Phosphorylation of Pik3cb 1 0.45 0.69 1.11
5 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09
6 INT121727 Pik3cb Positive_regulation of Ephb1 1 0.49 0.6 1.06
7 INT214368 Pik3cb Regulation of Ubqln1 1 0.01 0.36 0.68
8 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
9 INT261482 Pik3cb Positive_regulation of Phosphorylation of Ephb1 1 0.23 0.67 0.58
10 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
11 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
12 INT322394 Hist1h1t Positive_regulation of Pik3cb 1 0.01 0 0.42
13 INT214374 Pik3cb Regulation of Gene_expression of Slc6a3 1 0.37 0.3 0.35
14 INT122755 Helt Positive_regulation of Pik3cb 1 0.00 0.19 0.35
15 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32
16 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26
17 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26
18 INT352945 Fig4 Regulation of Negative_regulation of Pik3cb 1 0.03 0.38 0.19
19 INT226209 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.10 1.16 0.17
20 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
21 INT291550 St8sia2 Positive_regulation of Pik3cb 1 0.05 0.36 0.11
22 INT352943 Pik3cb Positive_regulation of Pdk1 1 0.09 0.21 0.06
23 INT352942 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.33 0.21 0.06
24 INT352941 Pik3cb Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.21 0.06
25 INT238314 Pik3cb Negative_regulation of Localization of Slc2a4 1 0.06 0.25 0.05
26 INT341021 Positive_regulation of Cp Positive_regulation of Positive_regulation of PIK3CB 1 0.00 0.15 0.04
27 INT341016 Reln Positive_regulation of Positive_regulation of PIK3CB 1 0.01 0.15 0.04
28 INT250665 EGFR Positive_regulation of PIK3CB 1 0.21 1.39 0
29 INT226190 Binding of Igf1 and Positive_regulation of Pik3cb 1 0.17 1.04 0
30 INT250659 Negative_regulation of PTEN Positive_regulation of Positive_regulation of PIK3CB 1 0.02 1.18 0
31 INT307457 Negative_regulation of Pik3cb Positive_regulation of Gsk3a 1 0.06 0.08 0
32 INT340504 Agtr1a Negative_regulation of Phosphorylation of Pik3cb 1 0.06 1.16 0
33 INT315057 Binding of TOP1 and PAR4 1 0.16 1.23 0
34 INT340927 Negative_regulation of PIK3CB Negative_regulation of Positive_regulation of AKT1 1 0.00 0 0
35 INT309870 Arl6ip6 Negative_regulation of Pik3cb 1 0.00 0.73 0
36 INT341025 PIK3CB Positive_regulation of Regulation of Vim 1 0.01 0 0
37 INT226207 Binding of Ins1 and Positive_regulation of Pik3cb 1 0.01 2.08 0
38 INT271101 PIK3CB Regulation of Akt1 1 0.01 0.72 0
39 INT340929 VLDLR Positive_regulation of PIK3CB 1 0.01 0.06 0
40 INT250666 ERBB2 Positive_regulation of PIK3CB 1 0.15 0.69 0
41 INT341020 PIK3CB Regulation of Gene_expression of Fabp7 1 0.02 0 0
42 INT226193 Gtf3a Positive_regulation of Pik3cb 1 0.00 1.02 0
43 INT353542 Pik3cb Regulation of Gene_expression of ONECUT1 1 0.00 0.08 0
44 INT250718 PIK3CB Regulation of Gene_expression of Birc5 1 0.23 0.91 0
45 INT340924 PIK3CB Negative_regulation of Positive_regulation of AKT1 1 0.00 0 0
46 INT294828 DPYD Positive_regulation of PIK3CB 1 0.00 0.51 0
47 INT149429 ERCC2 Negative_regulation of Localization of IL8 1 0.05 0.38 0
48 INT341023 PIK3CB Positive_regulation of Nrg1 1 0.03 0.06 0
49 INT283718 Binding of Id2 and Aatf 1 0.03 0.19 0
50 INT347290 Positive_regulation of CCL16 Positive_regulation of PIK3CB 1 0.03 0.57 0
51 INT227840 Binding of ERCC2 and ERCC6 1 0.11 0.66 0
52 INT149431 ERCC2 Negative_regulation of Localization of Il6 1 0.14 0.2 0
53 INT227831 Binding of ERCC2 and PGBD3 1 0.07 0.23 0
54 INT250664 PIK3CB Positive_regulation of AKT1 1 0.09 0.62 0
55 INT250660 PIK3CB Negative_regulation of AKT1 1 0.09 0.83 0
56 INT305543 Binding of Top2a and Trp53 1 0.37 0.91 0
57 INT149432 ERCC2 Regulation of Localization of Il6 1 0.15 1.06 0
58 INT149428 ERCC2 Regulation of Localization of IL8 1 0.05 0.53 0
59 INT341022 PIK3CB Regulation of Gene_expression of Erbb3 1 0.01 0 0
60 INT307452 Negative_regulation of Pik3cb Positive_regulation of Phosphorylation of Gsk3a 1 0.06 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for embryonic cleavage. They are ordered first by their pain relevance and then by number of times they were reported in embryonic cleavage. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT120966 Positive_regulation of Pik3cb 34 0.68 15.15 16.59
2 INT94573 Negative_regulation of Pik3cb 42 0.50 15.83 15.4
3 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
4 INT116643 Phosphorylation of Pik3cb 12 0.80 4.73 3.87
5 INT116645 Regulation of Pik3cb 11 0.41 3.78 3.43
6 INT128745 Positive_regulation of Positive_regulation of Pik3cb 4 0.56 0.95 2.24
7 INT149335 Gene_expression of Pik3cb 10 0.57 2.93 1.82
8 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78
9 INT250707 Gene_expression of PIK3CB 15 0.31 5.4 1.34
10 INT121723 Regulation of Positive_regulation of Pik3cb 1 0.44 0.61 1.29
11 INT142950 Protein_catabolism of ERCC2 2 0.25 1.45 1.14
12 INT250708 Negative_regulation of PIK3CB 17 0.30 3.09 0.94
13 INT194633 Negative_regulation of Gene_expression of Pik3cb 3 0.21 1.83 0.79
14 INT120963 Negative_regulation of Negative_regulation of Pik3cb 2 0.17 1.4 0.64
15 INT120961 Positive_regulation of Phosphorylation of Pik3cb 3 0.26 1.02 0.53
16 INT230238 Binding of Pik3cb 6 0.21 2.27 0.51
17 INT134070 Binding of ERCC2 3 0.27 0.76 0.51
18 INT103901 Regulation of ERCC2 1 0.23 0.51 0.4
19 INT120968 Negative_regulation of Phosphorylation of Pik3cb 1 0.12 0.89 0.39
20 INT194629 Positive_regulation of Gene_expression of Pik3cb 4 0.24 0.67 0.36
21 INT250712 Regulation of PIK3CB 2 0.15 0.88 0.25
22 INT214364 Positive_regulation of Negative_regulation of Pik3cb 1 0.42 0.19 0.25
23 INT120969 Negative_regulation of Positive_regulation of Pik3cb 2 0.19 0.69 0.24
24 INT178118 Positive_regulation of PIK3CB 12 0.32 5.06 0.19
25 INT172100 Binding of TOP1 2 0.14 1.31 0.11
26 INT268846 Negative_regulation of Top2a 6 0.29 3.06 0.07
27 INT200136 Negative_regulation of ERCC2 1 0.37 1.91 0.07
28 INT78478 Negative_regulation of TOP1 3 0.21 1.75 0.06
29 INT230239 Positive_regulation of Localization of Pik3cb 1 0.06 0.56 0.06
30 INT230240 Localization of Pik3cb 1 0.09 0.56 0.06
31 INT250703 Negative_regulation of Negative_regulation of PIK3CB 2 0.20 1.16 0.03
32 INT291906 Positive_regulation of Negative_regulation of ERCC2 1 0.40 0 0.03
33 INT235686 Gene_expression of Top2a 5 0.60 4.34 0
34 INT250702 Positive_regulation of Gene_expression of PIK3CB 3 0.23 1.79 0
35 INT347315 Binding of PIK3CB 2 0.19 1.57 0
36 INT283691 Binding of Aatf 2 0.03 0.19 0
37 INT268847 Binding of Top2a 2 0.24 0.6 0
38 INT340980 Negative_regulation of Positive_regulation of PIK3CB 2 0.12 0.59 0
39 INT322525 Phosphorylation of PIK3CB 2 0.42 1.09 0
40 INT290913 Negative_regulation of Binding of Pik3cb 1 0.21 0 0
41 INT283704 Phosphorylation of Aatf 1 0.05 0.19 0
42 INT256679 Gene_expression of Aatf 1 0.65 0.71 0
43 INT256916 Regulation of Gene_expression of Top2a 1 0.47 1.2 0
44 INT340989 Localization of PIK3CB 1 0.06 0 0
45 INT286557 Regulation of Binding of Aatf 1 0.02 0 0
46 INT149430 Localization of ERCC2 1 0.43 0.76 0
47 INT256921 Regulation of Top2a 1 0.21 1.28 0
48 INT268845 Positive_regulation of Binding of Top2a 1 0.05 0.33 0
49 INT271099 Regulation of Gene_expression of PIK3CB 1 0.08 0.62 0
50 INT273508 Negative_regulation of Gene_expression of Top2a 1 0.21 0.17 0
51 INT322533 Negative_regulation of Gene_expression of PIK3CB 1 0.11 0.57 0
52 INT307484 Regulation of Negative_regulation of Pik3cb 1 0.22 0.14 0
53 INT340998 Positive_regulation of Positive_regulation of PIK3CB 1 0.04 0.14 0
54 INT322530 Negative_regulation of Phosphorylation of PIK3CB 1 0.15 0.24 0
55 INT322527 Regulation of Negative_regulation of PIK3CB 1 0.07 0 0
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