GO:0040036

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Name regulation of fibroblast growth factor receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0040036
Unique Molecular Interactions 43
Total Molecular Interactions 89
Total Single Events 683
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of fibroblast growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for regulation of fibroblast growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT269444 Binding of RAB5A and HHIP 1 0.04 0 5.79
2 INT269443 Positive_regulation of Binding of RAB5A and HHIP 1 0.04 0 1.06
3 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
4 INT269454 Positive_regulation of Binding of GOPC and HHIP 1 0.01 0 0.73
5 INT274871 Positive_regulation of Cbr2 Positive_regulation of Positive_regulation of Dusp6 1 0.02 0.72 0.67
6 INT269442 Binding of GOPC and HHIP 1 0.01 0 0.52
7 INT269448 HHIP Positive_regulation of Binding of RAB5A 1 0.04 0 0.42
8 INT269456 RAB5A Regulation of Binding of HHIP 1 0.04 0 0.38
9 INT324224 Binding of OTX2 and H9 1 0.11 0.17 0.33
10 INT274872 Positive_regulation of Cbr2 Positive_regulation of Dusp6 1 0.02 0.63 0.32
11 INT269459 Binding of ISYNA1 and HHIP 1 0.00 0 0.27
12 INT269490 Binding of Racgap1 and HHIP 1 0.00 0 0.27
13 INT277613 Binding of HDAC9 and Runx2 1 0.02 0.59 0.26
14 INT256656 Binding of EP300 and HHIP 1 0.22 0 0.24
15 INT269446 Binding of EPHA3 and HHIP 1 0.01 0 0.2
16 INT274832 Dusp6 Positive_regulation of Localization of Tlr4 1 0.00 0 0.19
17 INT269451 Negative_regulation of Binding of RAB5A and HHIP 1 0.03 0 0.15
18 INT75058 Negative_regulation of ACE Negative_regulation of HHIP 1 0.25 0.43 0.15
19 INT269452 RAB5A Regulation of Localization of HHIP 1 0.04 0 0.15
20 INT223963 Binding of Bglap and Runx2 1 0.14 1.74 0.13
21 INT269445 Localization of HHIP Regulation of Gene_expression of RAB5A 1 0.03 0 0.13
22 INT269457 RAB5A Regulation of Regulation of HHIP 1 0.02 0 0.13
23 INT311905 Binding of Runx2 and Smad1 1 0.12 0.46 0.13
24 INT269458 HHIP Regulation of Gene_expression of RAB5A 1 0.04 0 0.1
25 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07
26 INT267017 Bdnf Positive_regulation of Dusp6 1 0.13 0.1 0.07
27 INT303560 Binding of Fgfr2 and Fgf22 1 0.41 0.89 0.07
28 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
29 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
30 INT274833 Negative_regulation of Dusp6 Positive_regulation of Mapk1 1 0.01 0 0.04
31 INT274830 Tlr4 Positive_regulation of Gene_expression of Dusp6 1 0.00 0.06 0.03
32 INT269453 HHIP Positive_regulation of RAB5A 1 0.04 0 0.03
33 INT303558 Binding of Fgfr2 and Dysf 1 0.01 0.44 0.03
34 INT274829 Tlr4 Regulation of Gene_expression of Dusp6 1 0.00 0.06 0.03
35 INT183090 Gene_expression of SULF1 Positive_regulation of Phosphorylation of FGF2 1 0.19 0.42 0
36 INT183091 Binding of FGF2 and FGFR2 1 0.03 0.79 0
37 INT342265 Binding of VDR and HHIP 1 0.00 0.93 0
38 INT183093 SULF1 Negative_regulation of Binding of FGF2 1 0.17 0.41 0
39 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
40 INT277610 Binding of Runx2 and Hdac4 1 0.32 0.78 0
41 INT274831 Dusp6 Positive_regulation of Tlr4 1 0.00 0 0
42 INT183089 Positive_regulation of Binding of FGF2 and FGFR2 1 0.04 0.4 0
43 INT183134 Binding of SULF1 and Panc1 1 0.03 0.42 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of fibroblast growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in regulation of fibroblast growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125477 Gene_expression of HHIP 91 0.78 31.18 12.57
2 INT183119 Gene_expression of SULF1 1 0.75 46.71 5.44
3 INT178763 Binding of HHIP 37 0.08 6.3 5.29
4 INT125478 Localization of HHIP 32 0.80 3.43 4.68
5 INT125479 Positive_regulation of HHIP 38 0.44 12.39 3.75
6 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55
7 INT125480 Regulation of HHIP 17 0.38 6.16 2.16
8 INT274884 Positive_regulation of Dusp6 1 0.07 2.08 1.52
9 INT274892 Gene_expression of Dusp6 1 0.08 1.81 1.4
10 INT183127 Localization of SULF1 1 0.77 3.45 1.13
11 INT125476 Regulation of Gene_expression of HHIP 2 0.39 1.1 1.1
12 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08
13 INT269487 Positive_regulation of Binding of HHIP 1 0.06 0 1.08
14 INT43484 Binding of Runx2 7 0.37 3.22 0.95
15 INT274888 Negative_regulation of Dusp6 1 0.06 1.82 0.93
16 INT269485 Positive_regulation of Gene_expression of HHIP 9 0.41 1.08 0.92
17 INT183182 Negative_regulation of FGFR2 2 0.29 1.25 0.84
18 INT142123 Positive_regulation of Gene_expression of Runx2 17 0.64 4.81 0.65
19 INT158136 Binding of FGFR2 9 0.26 4.5 0.63
20 INT274881 Regulation of Dusp6 1 0.04 0.9 0.63
21 INT269461 Positive_regulation of Localization of HHIP 1 0.05 0 0.63
22 INT269465 Positive_regulation of Positive_regulation of HHIP 4 0.11 0.5 0.62
23 INT274885 Negative_regulation of Gene_expression of Dusp6 1 0.04 0.89 0.6
24 INT183133 Negative_regulation of Localization of SULF1 1 0.41 1.34 0.59
25 INT216363 Gene_expression of OTX2 4 0.54 0.32 0.55
26 INT274880 Negative_regulation of Positive_regulation of Dusp6 1 0.04 0.89 0.52
27 INT146778 Negative_regulation of Fgfr2 1 0.32 0.66 0.48
28 INT178766 Negative_regulation of HHIP 19 0.28 11.1 0.43
29 INT202626 Negative_regulation of Fgfr2 2 0.41 2.48 0.42
30 INT183114 Positive_regulation of Gene_expression of SULF1 1 0.48 7.61 0.37
31 INT183116 Positive_regulation of SULF1 1 0.67 3.22 0.34
32 INT274883 Positive_regulation of Gene_expression of Dusp6 1 0.07 0.39 0.27
33 INT274876 Positive_regulation of Positive_regulation of Dusp6 1 0.04 0.49 0.25
34 INT176080 Gene_expression of Fgfr2 4 0.68 2.34 0.24
35 INT142117 Regulation of Runx2 6 0.61 2.75 0.22
36 INT223739 Binding of Fgfr2 3 0.30 0.94 0.22
37 INT269484 Negative_regulation of Localization of HHIP 1 0.04 0 0.22
38 INT269463 Phosphorylation of HHIP 1 0.05 0 0.22
39 INT269489 Positive_regulation of Phosphorylation of HHIP 1 0.04 0 0.22
40 INT171614 Positive_regulation of Runx2 13 0.63 3.04 0.19
41 INT171605 Negative_regulation of Runx2 4 0.46 2.14 0.17
42 INT269464 Negative_regulation of Gene_expression of HHIP 4 0.10 0.74 0.16
43 INT269486 Regulation of Localization of HHIP 1 0.04 0 0.15
44 INT183125 Negative_regulation of SULF1 2 0.42 2.26 0.13
45 INT99718 Positive_regulation of Gene_expression of FGFR2 9 0.49 4.47 0.12
46 INT183124 Regulation of Gene_expression of SULF1 1 0.59 1.92 0.1
47 INT211942 Transcription of Runx2 3 0.69 2.46 0.08
48 INT183129 Negative_regulation of Gene_expression of SULF1 1 0.56 5.19 0.07
49 INT303546 Binding of Fgfr2 1 0.46 0.74 0.06
50 INT183122 Regulation of SULF1 1 0.59 1.53 0.06
51 INT303525 Localization of Fgfr2 1 0.72 0.28 0.03
52 INT303547 Positive_regulation of Negative_regulation of Fgfr2 1 0.48 1.07 0.03
53 INT207729 Regulation of FGFR2 4 0.22 2.35 0
54 INT238985 Positive_regulation of FGFR2 3 0.49 1.19 0
55 INT99716 Transcription of FGFR2 2 0.34 0.22 0
56 INT305351 Positive_regulation of Regulation of FGFR2 2 0.37 0.97 0
57 INT99715 Regulation of Gene_expression of FGFR2 2 0.22 0.19 0
58 INT142118 Regulation of Gene_expression of Runx2 2 0.61 2.92 0
59 INT303555 Negative_regulation of Gene_expression of FGFR2 2 0.41 0.31 0
60 INT342268 Positive_regulation of Negative_regulation of HHIP 1 0.04 0.91 0
61 INT211944 Regulation of Transcription of Runx2 1 0.34 0.32 0
62 INT202623 Negative_regulation of Gene_expression of Fgfr2 1 0.32 0 0
63 INT319036 Gene_expression of Fgfr2 1 0.48 0.08 0
64 INT349060 Regulation of Negative_regulation of HHIP 1 0.10 1.33 0
65 INT233766 Negative_regulation of Regulation of HHIP 1 0.12 0.32 0
66 INT282947 Negative_regulation of OTX2 1 0.35 0 0
67 INT324222 Binding of OTX2 1 0.20 0 0
68 INT99717 Positive_regulation of Transcription of FGFR2 1 0.10 0.08 0
69 INT269469 Regulation of Positive_regulation of HHIP 1 0.04 0 0
70 INT183117 Positive_regulation of Binding of FGFR2 1 0.09 0.81 0
71 INT265814 Localization of Runx2 1 0.75 0.84 0
72 INT277589 Regulation of Negative_regulation of Runx2 1 0.36 0.78 0
73 INT183128 Transcription of SULF1 1 0.66 0.17 0
74 INT265813 Regulation of Binding of Runx2 1 0.27 0.19 0
75 INT303524 Positive_regulation of Fgfr2 1 0.66 0.22 0
76 INT171613 Positive_regulation of Positive_regulation of Runx2 1 0.01 0 0
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