GO:0042053

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Name regulation of dopamine metabolic process
Categary Process
Go Slim No
Go Link GO:0042053
Unique Molecular Interactions 240
Total Molecular Interactions 409
Total Single Events 2632
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of dopamine metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for regulation of dopamine metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
2 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
3 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19
4 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64
5 INT314141 Binding of Tacr3 and SFTPA1 1 0.00 3.02 2.48
6 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
7 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
8 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76
9 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 0.14 0 1.7
10 INT172206 Binding of Slc6a3 and ADHD1 2 0.03 2.76 1.61
11 INT100908 Slc6a3 Regulation of Positive_regulation of Etf1 1 0.05 0 1.41
12 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
13 INT119713 Negative_regulation of Slc6a3 Positive_regulation of Cpu3 1 0.39 0.71 1.26
14 INT111211 Binding of Drd4 and Chdh 1 0.01 1.34 1.26
15 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
16 INT184919 Binding of da and Slc6a3 1 0.12 0.33 1.23
17 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
18 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
19 INT90644 Slc6a3 Positive_regulation of Th 1 0.51 0 1.2
20 INT76256 Binding of Slc6a3 and Sigmar1 1 0.20 0 1.16
21 INT336559 SLC6A3 Positive_regulation of GOPC 1 0.08 1 1.15
22 INT321476 Binding of Slc6a3 and Slc6a2 1 0.01 0.41 1.14
23 INT321473 Binding of Slc6a3 and Ubqln1 1 0.00 0.41 1.13
24 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
25 INT86263 Binding of Tacr3 and Tac2 1 0.16 0.52 1.13
26 INT73679 Nkx1-1 Positive_regulation of Tacr3 1 0.22 0.26 1.12
27 INT74185 Cck Negative_regulation of Drd1a 1 0.30 0.1 1.1
28 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
29 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
30 INT87854 Binding of Drd1a and Positive_regulation of Localization of Abat 1 0.08 0 0.96
31 INT74184 Cck Regulation of Localization of Drd1a 1 0.32 0.06 0.95
32 INT314142 Binding of TAC1 and Tacr3 1 0.06 0.73 0.94
33 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
34 INT136172 NPY Negative_regulation of Positive_regulation of Drd1a 1 0.21 0 0.91
35 INT7292 Binding of Drd1a and Penk 1 0.14 0 0.9
36 INT52760 Oprd1 Regulation of Drd1a 1 0.02 0 0.9
37 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
38 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
39 INT29279 Binding of Drd1a and Htr1a 1 0.35 0.2 0.84
40 INT344101 Positive_regulation of Drd1a Positive_regulation of Localization of Abat 1 0.01 0 0.84
41 INT214370 Slc6a3 Regulation of Amph 1 0.14 0.44 0.82
42 INT353721 Negative_regulation of Binding of Drd1a and Ghsr 1 0.16 0 0.76
43 INT353720 Binding of Drd1a and Ghsr 1 0.18 0 0.76
44 INT15344 Oprd1 Regulation of Localization of Tacr3 1 0.00 0 0.76
45 INT21260 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.05 0 0.76
46 INT49044 Tac2 Regulation of Gene_expression of Tacr3 1 0.17 0.32 0.76
47 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74
48 INT210144 Binding of Slc6a3 and Slc37a4 1 0.11 0.23 0.72
49 INT99938 Drd1a Regulation of Transcription of Qrfp 1 0.03 0 0.69
50 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68
51 INT99939 Drd1a Regulation of Qrfp 1 0.03 0 0.68
52 INT148257 NR4A2 Regulation of Gene_expression of SLC6A3 1 0.60 0.4 0.59
53 INT317638 Ins1 Positive_regulation of Gene_expression of Drd1a 1 0.14 0.86 0.59
54 INT317634 Ins1 Positive_regulation of Drd1a 1 0.14 0.86 0.59
55 INT336557 SLC6A3 Positive_regulation of Binding of GOPC 1 0.08 0.5 0.58
56 INT270935 Cpe Regulation of Phosphorylation of Slc6a3 1 0.31 0 0.57
57 INT270984 Slc6a3 Regulation of IGKC 1 0.02 0 0.53
58 INT5111 DIO2 Positive_regulation of Drd1a 1 0.04 0 0.53
59 INT223925 Drd1a Positive_regulation of Gene_expression of Serpina1 1 0.01 0 0.51
60 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51
61 INT270937 Cpe Regulation of Slc6a3 1 0.36 0 0.5
62 INT172207 Binding of Drd4 and ADHD1 2 0.03 1.56 0.48
63 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48
64 INT184877 Negative_regulation of Binding of Slc6a3 and ADHD1 1 0.01 0.69 0.45
65 INT90642 Cpe Negative_regulation of Negative_regulation of Slc6a3 1 0.04 0 0.44
66 INT157451 Binding of Slc6a3 and Dbh 1 0.04 0.48 0.44
67 INT317635 Positive_regulation of Drd1a Positive_regulation of Phosphorylation of Gtf3a 1 0.01 0.53 0.43
68 INT344104 Binding of Slc6a3 and Obfc1 1 0.00 0 0.43
69 INT86972 PDE1B Positive_regulation of Localization of Gh 1 0.00 0 0.42
70 INT51026 Klra3 Positive_regulation of Gene_expression of Tacr3 1 0.05 0 0.42
71 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4
72 INT32244 Slc3a1 Positive_regulation of Localization of Drd1a 1 0.15 0 0.39
73 INT32243 Drd1a Positive_regulation of Localization of Slc3a1 1 0.15 0 0.39
74 INT344103 Positive_regulation of Drd1a Positive_regulation of Obfc1 1 0.00 0 0.38
75 INT353391 Binding of DRD4 and GRB2 1 0.37 0.62 0.37
76 INT37247 Binding of Drd1a and Drd2 1 0.20 0 0.37
77 INT353392 Binding of DRD4 and NCK1 1 0.37 0.62 0.37
78 INT353390 Binding of DRD4 and SRC 1 0.25 0.62 0.37
79 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37
80 INT190003 Binding of MVD and Slc6a3 1 0.13 0.19 0.37
81 INT270939 Gene_expression of Cpe Positive_regulation of Slc6a3 1 0.20 0 0.36
82 INT214374 Pik3cb Regulation of Gene_expression of Slc6a3 1 0.37 0.3 0.35
83 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
84 INT102341 Binding of Slc6a3 and Flvcr2 2 0.06 0 0.34
85 INT127887 SLC6A3 Regulation of Drd2 1 0.34 0.68 0.34
86 INT102340 Binding of Slc6a3 and Sert1 1 0.18 0 0.34
87 INT79383 Pde1b Regulation of Oprd1 1 0.02 0 0.34
88 INT106871 Grip2 Regulation of Tacr3 1 0.00 0 0.32
89 INT258764 Binding of Drd4 and ADHD1 1 0.08 1.11 0.31
90 INT90643 Negative_regulation of Slc6a3 Positive_regulation of Th 1 0.47 0 0.3
91 INT99599 ZNF398 Negative_regulation of NR4A2 1 0.05 0.41 0.3
92 INT99600 ZNF398 Negative_regulation of Transcription of NR4A2 1 0.10 0.41 0.3
93 INT270954 Gene_expression of Cpe Positive_regulation of Gene_expression of Slc6a3 1 0.23 0 0.28
94 INT97595 Penk Regulation of Gene_expression of Drd1a 1 0.25 0.1 0.28
95 INT270955 Cpe Regulation of Gene_expression of Slc6a3 1 0.14 0 0.25
96 INT73385 Cfp Regulation of Drd1a 1 0.10 0 0.25
97 INT294912 Binding of Pax3 and Tacr3 1 0.01 1.54 0.25
98 INT73384 Positive_regulation of Cfp Regulation of Drd1a 1 0.18 0 0.25
99 INT270951 Regulation of Binding of Slc6a3 and Cpe 1 0.23 0 0.25
100 INT214366 Ins1 Regulation of Slc6a3 1 0.11 0.09 0.25
101 INT70659 Binding of Tacr3 and Hrasls 1 0.00 0 0.24
102 INT278578 Tacr3 Positive_regulation of Tacr1 1 0.55 0 0.24
103 INT261465 Binding of Drd1a and Ptgdr 1 0.03 0.1 0.23
104 INT270940 Negative_regulation of Binding of Slc6a3 and Cpe 1 0.25 0 0.23
105 INT149973 MC1R Positive_regulation of Gene_expression of NR4A2 1 0.44 0.32 0.23
106 INT270948 Cpe Regulation of Regulation of Slc6a3 1 0.14 0.28 0.23
107 INT201440 Negative_regulation of Ngf Positive_regulation of Slc6a3 1 0.10 0 0.2
108 INT270947 Cpe Negative_regulation of Phosphorylation of Slc6a3 1 0.25 0 0.2
109 INT300562 Binding of Slc6a3 and Datd 1 0.02 1.12 0.2
110 INT201443 Ngf Positive_regulation of Slc6a3 1 0.11 0 0.19
111 INT184868 Binding of Slc6a3 and Lmo1 1 0.02 0.72 0.19
112 INT276065 Camk2a Negative_regulation of Pde1b 1 0.56 0 0.17
113 INT349505 Ptpn2 Negative_regulation of Slc6a3 1 0.19 0.7 0.16
114 INT278576 Olfr714 Regulation of Gene_expression of Tacr3 1 0.10 0 0.15
115 INT276060 Pde1b Regulation of Car2 1 0.30 0 0.15
116 INT273017 Binding of PDE1B and PDE11A 1 0.08 0.35 0.14
117 INT241070 Klf16 Positive_regulation of Drd1a 1 0.05 0.13 0.12
118 INT197317 Nr4a2 Regulation of Gene_expression of Th 1 0.03 0.07 0.12
119 INT258761 Binding of Slc6a3 and ADHD1 1 0.03 0.51 0.12
120 INT276079 Pde1b Negative_regulation of Camk2a 1 0.41 0 0.12
121 INT278573 Atp6v1e1 Regulation of Gene_expression of Tacr3 1 0.17 0.07 0.09
122 INT184920 Binding of Agtrap and Slc6a3 1 0.02 0.09 0.09
123 INT341776 ESR1 Positive_regulation of Gene_expression of SLC6A3 1 0.06 0.08 0.09
124 INT258758 Binding of Drd4 and Lmo1 1 0.04 0.64 0.08
125 INT201446 GOPC Positive_regulation of Slc6a3 1 0.03 0.07 0.08
126 INT184917 Slc6a3 Positive_regulation of Agtrap 1 0.03 0.08 0.06
127 INT261454 Akr1d1 Regulation of Drd1a 1 0.00 0.71 0.06
128 INT276067 Binding of Car2 and Pde1b 1 0.32 0 0.06
129 INT276050 Binding of Calm3 and Pde1b 1 0.15 0 0.06
130 INT201439 Dlat Regulation of Localization of Slc6a3 1 0.04 0 0.06
131 INT276049 Pde1b Regulation of Positive_regulation of Rpa1 1 0.04 0 0.06
132 INT321651 Binding of Slc6a3 and Uts2r 1 0.04 0.06 0.05
133 INT321652 Binding of Slc6a3 and Slc6a4 1 0.26 0.07 0.05
134 INT201445 ESR1 Regulation of Slc6a3 1 0.02 0.05 0.04
135 INT201442 Dlat Regulation of Slc6a3 1 0.04 0.18 0.04
136 INT270950 Binding of Slc6a3 and Tgfb1i1 1 0.02 0.23 0.04
137 INT278572 Atp6v1e1 Negative_regulation of Gene_expression of Tacr3 1 0.22 0 0.03
138 INT270985 Binding of Slc6a3 and GSTK1 1 0.02 0.05 0.03
139 INT202573 Binding of DIO2 and DRD4 1 0.07 0.09 0.03
140 INT276036 Negative_regulation of Pde1b Positive_regulation of Phosphorylation of Prkaca 1 0.27 0 0.03
141 INT276055 Negative_regulation of Pde1b Positive_regulation of Prkaca 1 0.27 0 0.03
142 INT276070 Negative_regulation of Pde1b Positive_regulation of Phosphorylation of Ppp1r1b 1 0.24 0 0.03
143 INT270956 Slc6a3 Positive_regulation of Cpe 1 0.29 0 0.03
144 INT270941 Slc6a3 Positive_regulation of Binding of Cpe 1 0.29 0 0.03
145 INT276044 Binding of Pde1b and Ppp1cc 1 0.12 0 0
146 INT276048 Binding of Pde1b and Myoz1 1 0.04 0 0
147 INT89016 Oprd1 Negative_regulation of Drd1a 1 0.06 0 0
148 INT90319 Binding of Slc6a3 and Positive_regulation of Regulation of Oprl1 1 0.14 0 0
149 INT202571 Binding of DRD2 and DRD4 1 0.41 0.76 0
150 INT276078 Binding of Camk2a and Pde1b 1 0.36 0 0
151 INT263182 Ca2 Positive_regulation of Phosphorylation of Pde1b 1 0.01 0 0
152 INT276052 Negative_regulation of Pde1b Negative_regulation of Camk2a 1 0.41 0 0
153 INT276058 Camk2a Regulation of Pde1b 1 0.26 0 0
154 INT263183 Binding of Pde1b and Pde5a 1 0.03 0 0
155 INT276042 Negative_regulation of Binding of Calm3 and Pde1b 1 0.17 0 0
156 INT276047 Camk2a Regulation of Negative_regulation of Pde1b 1 0.43 0 0
157 INT276051 Pde1b Regulation of Regulation of Car2 1 0.30 0 0
158 INT276071 Pde1b Regulation of Positive_regulation of Camk2a 1 0.43 0 0
159 INT299445 Lhb Positive_regulation of Gene_expression of Nr4a2 1 0.22 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of dopamine metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in regulation of dopamine metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5858 Positive_regulation of Drd1a 66 0.69 4.51 51.73
2 INT81037 Negative_regulation of Slc6a3 70 0.59 15.31 37.01
3 INT93360 Gene_expression of Slc6a3 63 0.78 19.54 26.55
4 INT80791 Gene_expression of Slc6a3 113 0.78 11.89 25.76
5 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43
6 INT13838 Positive_regulation of Drd1a 48 0.70 9.83 23.42
7 INT61825 Negative_regulation of Slc6a3 47 0.59 6.52 21.27
8 INT7680 Regulation of Drd1a 27 0.45 4.52 18.86
9 INT51779 Gene_expression of Drd1a 46 0.66 11.18 17.51
10 INT7020 Negative_regulation of Drd1a 25 0.57 1.84 17.1
11 INT65214 Binding of Slc6a3 54 0.48 4.77 16.79
12 INT5859 Positive_regulation of Positive_regulation of Drd1a 20 0.55 2.05 15.61
13 INT54356 Regulation of Slc6a3 48 0.58 5.86 15.24
14 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23
15 INT24956 Gene_expression of Tacr3 22 0.74 7.21 13.37
16 INT28458 Localization of Slc6a3 31 0.76 2.33 12.49
17 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41
18 INT7682 Binding of Drd1a 22 0.48 1.8 11.83
19 INT93967 Binding of Slc6a3 22 0.48 6.81 10.74
20 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69
21 INT90639 Positive_regulation of Slc6a3 25 0.61 10.95 10.41
22 INT16735 Localization of Drd1a 11 0.61 0.35 8.42
23 INT146343 Regulation of Slc6a3 17 0.60 7.33 8.27
24 INT28461 Positive_regulation of Localization of Slc6a3 8 0.41 0 8.24
25 INT184845 Negative_regulation of Gene_expression of Slc6a3 13 0.59 3.25 7.79
26 INT28457 Positive_regulation of Slc6a3 26 0.50 3.64 7.76
27 INT22369 Negative_regulation of Drd1a 15 0.47 6.13 6.87
28 INT21552 Regulation of Drd1a 10 0.57 3.7 6.05
29 INT14490 Positive_regulation of Tacr3 14 0.53 1.83 5.77
30 INT18366 Negative_regulation of Positive_regulation of Drd1a 6 0.42 0.49 5.54
31 INT101925 Binding of Drd1a 9 0.43 1.82 4.97
32 INT25831 Gene_expression of NR4A2 20 0.74 2.73 4.92
33 INT48567 Transcription of Drd1a 7 0.51 2.44 4.54
34 INT113078 Phosphorylation of Drd1a 4 0.30 0.77 4.45
35 INT13333 Regulation of Gene_expression of Drd1a 8 0.36 3.37 4.28
36 INT201438 Phosphorylation of Slc6a3 3 0.68 0.79 4.19
37 INT183479 Positive_regulation of Gene_expression of Slc6a3 16 0.57 0.91 4.13
38 INT88274 Positive_regulation of Drd4 7 0.69 3.48 4.1
39 INT8950 Gene_expression of Tacr3 12 0.76 0.97 4.07
40 INT119053 Positive_regulation of SLC6A3 15 0.65 2.51 4
41 INT5299 Regulation of Tacr3 11 0.34 1.51 3.93
42 INT15343 Localization of Tacr3 7 0.76 2.11 3.69
43 INT214362 Negative_regulation of Gene_expression of Slc6a3 7 0.41 1.58 3.67
44 INT8952 Negative_regulation of Tacr3 7 0.42 0.36 3.62
45 INT146342 Negative_regulation of Negative_regulation of Slc6a3 5 0.44 3.34 3.4
46 INT62901 Positive_regulation of Gene_expression of Drd1a 2 0.57 0.66 3.35
47 INT8599 Binding of Tacr3 6 0.21 0.19 3.2
48 INT109095 Binding of Drd4 7 0.40 3.6 3.18
49 INT13335 Negative_regulation of Gene_expression of Drd1a 6 0.34 0.8 3.16
50 INT122577 Regulation of SLC6A3 9 0.53 1.47 3.09
51 INT18365 Positive_regulation of Regulation of Drd1a 4 0.50 1.74 3.04
52 INT167547 Positive_regulation of Gene_expression of Slc6a3 8 0.46 3.33 3.03
53 INT54355 Transcription of Slc6a3 6 0.61 0.28 3.02
54 INT88273 Gene_expression of Drd4 6 0.54 1.84 3.01
55 INT71398 Regulation of Tacr3 5 0.53 1.15 2.91
56 INT28460 Negative_regulation of Localization of Slc6a3 5 0.36 0.24 2.9
57 INT113077 Positive_regulation of Phosphorylation of Drd1a 1 0.11 0.15 2.87
58 INT19235 Negative_regulation of PDE1B 11 0.14 2.38 2.81
59 INT147412 Binding of DRD4 11 0.47 7.57 2.77
60 INT189863 Gene_expression of DRD4 11 0.68 7.65 2.66
61 INT64248 Positive_regulation of Positive_regulation of Drd1a 6 0.45 1.97 2.62
62 INT89992 Positive_regulation of Gene_expression of Drd1a 5 0.39 2.11 2.54
63 INT88272 Gene_expression of Drd4 5 0.66 1.07 2.53
64 INT229111 Localization of SLC6A3 5 0.68 1.12 2.48
65 INT50723 Positive_regulation of Nr4a2 7 0.53 0.47 2.46
66 INT99607 Transcription of NR4A2 2 0.68 1.61 2.41
67 INT86462 Transcription of Drd1a 3 0.44 1.86 2.36
68 INT111584 Positive_regulation of Negative_regulation of Slc6a3 4 0.47 0.68 2.31
69 INT86262 Negative_regulation of Tacr3 3 0.41 0.57 2.2
70 INT24407 Negative_regulation of Binding of Drd1a 3 0.25 0.81 2.18
71 INT93965 Negative_regulation of Binding of Slc6a3 5 0.42 1.39 2.07
72 INT21046 Regulation of Positive_regulation of Drd1a 3 0.44 0.09 2.06
73 INT169552 Positive_regulation of Negative_regulation of Slc6a3 3 0.50 0.51 2.05
74 INT13837 Negative_regulation of Positive_regulation of Drd1a 2 0.43 1.43 2.01
75 INT95461 Positive_regulation of Regulation of Slc6a3 3 0.47 0 1.95
76 INT24230 Localization of Tacr3 3 0.21 0 1.94
77 INT77990 Protein_catabolism of Slc6a3 6 0.72 0.99 1.84
78 INT210140 Regulation of Gene_expression of Slc6a3 1 0.62 0.83 1.82
79 INT81169 Localization of Nr4a2 1 0.68 0 1.71
80 INT198952 Localization of Slc6a3 3 0.75 0.68 1.62
81 INT50724 Positive_regulation of Positive_regulation of Nr4a2 2 0.49 0.17 1.58
82 INT138083 Positive_regulation of Gene_expression of Drd4 2 0.40 1.34 1.55
83 INT58598 Regulation of Gene_expression of Tacr3 1 0.37 0.98 1.54
84 INT53008 Gene_expression of Nr4a2 25 0.74 4.89 1.5
85 INT49042 Positive_regulation of Gene_expression of Tacr3 2 0.42 0.7 1.5
86 INT140305 Negative_regulation of Binding of Drd1a 2 0.21 0.54 1.46
87 INT114808 Positive_regulation of Binding of SLC6A3 4 0.50 0.63 1.45
88 INT113079 Regulation of Phosphorylation of Drd1a 1 0.06 0.07 1.43
89 INT28456 Negative_regulation of Positive_regulation of Slc6a3 2 0.32 0 1.38
90 INT58597 Positive_regulation of Transcription of Tacr3 1 0.28 0.67 1.37
91 INT68451 Localization of Pde1b 4 0.22 0 1.35
92 INT99930 Positive_regulation of Gene_expression of SLC6A3 4 0.43 0.08 1.34
93 INT229116 Negative_regulation of Localization of SLC6A3 1 0.22 0.17 1.31
94 INT69498 Positive_regulation of DRD4 3 0.50 0.95 1.3
95 INT148262 Negative_regulation of Gene_expression of SLC6A3 2 0.38 1.66 1.29
96 INT102200 Gene_expression of Nr4a2 9 0.72 3.69 1.28
97 INT131984 Positive_regulation of Localization of Tacr3 1 0.01 0 1.28
98 INT73011 Gene_expression of Pde1b 3 0.23 0.38 1.27
99 INT138347 Phosphorylation of Slc6a3 2 0.71 1.01 1.26
100 INT156390 Regulation of Gene_expression of Slc6a3 2 0.37 0.28 1.22
101 INT28459 Regulation of Positive_regulation of Slc6a3 1 0.34 0 1.17
102 INT110400 Negative_regulation of Pde1b 21 0.50 0.58 1.14
103 INT58599 Transcription of Tacr3 3 0.43 1.02 1.12
104 INT184839 Localization of Drd1a 4 0.73 0.84 1.03
105 INT8951 Negative_regulation of Gene_expression of Tacr3 2 0.42 0.14 1.01
106 INT8948 Regulation of Negative_regulation of Tacr3 1 0.15 0 1.01
107 INT152000 Regulation of Regulation of Slc6a3 1 0.44 0.68 0.99
108 INT69302 Positive_regulation of Pde1b 3 0.21 0.99 0.97
109 INT133215 Transcription of Slc6a3 4 0.67 1.59 0.95
110 INT64690 Negative_regulation of Localization of Drd1a 2 0.09 0 0.95
111 INT74183 Positive_regulation of Localization of Drd1a 1 0.32 0.06 0.95
112 INT93969 Positive_regulation of Binding of Slc6a3 1 0.41 0.62 0.94
113 INT138346 Positive_regulation of Phosphorylation of Slc6a3 1 0.17 1.24 0.93
114 INT148259 Negative_regulation of Gene_expression of NR4A2 2 0.55 0.71 0.91
115 INT63785 Positive_regulation of Tacr3 2 0.11 0.08 0.88
116 INT99668 Positive_regulation of Binding of Drd1a 2 0.43 0.89 0.87
117 INT24957 Negative_regulation of Gene_expression of Tacr3 1 0.21 0.49 0.87
118 INT88271 Positive_regulation of Drd4 2 0.19 0.5 0.82
119 INT69749 Binding of Tacr3 3 0.06 2.2 0.81
120 INT148263 Transcription of SLC6A3 1 0.62 0.49 0.81
121 INT210141 Positive_regulation of Localization of Slc6a3 1 0.50 0.35 0.8
122 INT270962 Negative_regulation of Phosphorylation of Slc6a3 1 0.42 0 0.8
123 INT86261 Regulation of Localization of Tacr3 1 0.16 0.4 0.77
124 INT122578 Regulation of Gene_expression of SLC6A3 3 0.34 0.2 0.75
125 INT54354 Regulation of Transcription of Slc6a3 1 0.21 0.08 0.74
126 INT148261 Negative_regulation of Transcription of NR4A2 1 0.41 0.31 0.72
127 INT201436 Positive_regulation of Phosphorylation of Slc6a3 2 0.50 0.27 0.71
128 INT90714 Positive_regulation of Nr4a2 1 0.67 0.97 0.71
129 INT146344 Negative_regulation of Regulation of Slc6a3 2 0.32 1.17 0.7
130 INT153157 Regulation of Regulation of Drd1a 2 0.25 0.2 0.66
131 INT184848 Positive_regulation of Transcription of Drd1a 1 0.26 0.93 0.65
132 INT140306 Regulation of Binding of Drd1a 1 0.20 0.36 0.64
133 INT72516 Regulation of Binding of Drd1a 2 0.44 0.4 0.63
134 INT146345 Regulation of Binding of Slc6a3 1 0.34 0.22 0.61
135 INT86971 Localization of PDE1B 4 0.15 0.08 0.6
136 INT90637 Negative_regulation of Positive_regulation of Slc6a3 1 0.41 0 0.6
137 INT184911 Regulation of Negative_regulation of Slc6a3 1 0.36 0.06 0.59
138 INT149974 Positive_regulation of Gene_expression of NR4A2 4 0.41 0.52 0.58
139 INT148260 Negative_regulation of NR4A2 2 0.36 0.68 0.56
140 INT148258 Regulation of Gene_expression of NR4A2 1 0.26 0.39 0.56
141 INT135534 Regulation of Gene_expression of Drd4 1 0.30 0.18 0.56
142 INT148265 Regulation of Transcription of NR4A2 1 0.58 0.39 0.56
143 INT119054 Negative_regulation of Binding of SLC6A3 2 0.43 0 0.54
144 INT156210 Regulation of Positive_regulation of Drd4 1 0.45 0.72 0.49
145 INT89215 Negative_regulation of Binding of Slc6a3 1 0.26 0.06 0.48
146 INT86970 Positive_regulation of Localization of PDE1B 1 0.00 0 0.42
147 INT125938 Negative_regulation of Binding of Tacr3 1 0.24 0.14 0.42
148 INT184866 Positive_regulation of Binding of Drd4 1 0.20 0.87 0.41
149 INT281468 Positive_regulation of Positive_regulation of Slc6a3 1 0.42 0.34 0.4
150 INT106866 Positive_regulation of Binding of Tacr3 1 0.09 0 0.39
151 INT172201 Localization of Drd4 1 0.58 0.18 0.38
152 INT79379 Regulation of Pde1b 1 0.07 0 0.37
153 INT48566 Regulation of Transcription of Drd1a 1 0.32 0 0.37
154 INT88082 Negative_regulation of Drd4 1 0.18 0.65 0.35
155 INT242948 Gene_expression of PDE1B 1 0.02 0.91 0.34
156 INT276012 Gene_expression of Pde1b 8 0.66 0.58 0.32
157 INT276027 Positive_regulation of Pde1b 7 0.59 0.71 0.32
158 INT90716 Regulation of Gene_expression of Nr4a2 2 0.43 0.41 0.32
159 INT99609 Localization of NR4A2 2 0.73 0.6 0.3
160 INT99611 Negative_regulation of Localization of NR4A2 1 0.42 0.41 0.3
161 INT101780 Regulation of Regulation of Slc6a3 1 0.26 0 0.3
162 INT246013 Transcription of Nr4a2 4 0.46 1.29 0.27
163 INT353393 Transcription of DRD4 1 0.63 0.57 0.27
164 INT136052 Negative_regulation of Negative_regulation of Drd1a 1 0.13 0.66 0.27
165 INT148898 Negative_regulation of Gene_expression of Nr4a2 3 0.54 1.13 0.26
166 INT341786 Positive_regulation of Phosphorylation of SLC6A3 1 0.16 0.07 0.26
167 INT341782 Phosphorylation of SLC6A3 1 0.27 0.07 0.26
168 INT276798 Positive_regulation of NR4A2 2 0.16 0.08 0.25
169 INT270965 Positive_regulation of Positive_regulation of Slc6a3 1 0.36 0 0.25
170 INT274009 Positive_regulation of Positive_regulation of SLC6A3 1 0.43 0.09 0.25
171 INT270963 Positive_regulation of Binding of Slc6a3 1 0.36 0 0.25
172 INT91980 Positive_regulation of Positive_regulation of Tacr3 1 0.08 0.18 0.25
173 INT48343 Regulation of Regulation of Tacr3 1 0.04 0 0.25
174 INT326598 Negative_regulation of Negative_regulation of SLC6A3 1 0.28 0.65 0.24
175 INT137662 Negative_regulation of Drd4 2 0.39 0.86 0.23
176 INT100251 Regulation of PDE1B 4 0.26 1.21 0.22
177 INT172200 Transcription of Drd4 1 0.41 0.73 0.21
178 INT172199 Positive_regulation of Transcription of Drd4 1 0.36 0.73 0.21
179 INT300559 Positive_regulation of Gene_expression of Drd4 1 0.43 0.15 0.19
180 INT242946 Positive_regulation of Phosphorylation of PDE1B 1 0.01 0.22 0.17
181 INT275085 Transcription of PDE1B 1 0.04 0.27 0.16
182 INT349491 Negative_regulation of Transcription of Slc6a3 1 0.22 0.7 0.16
183 INT270974 Negative_regulation of Protein_catabolism of Slc6a3 1 0.42 0 0.15
184 INT270976 Positive_regulation of Protein_catabolism of Slc6a3 1 0.34 0 0.15
185 INT270970 Regulation of Binding of Slc6a3 1 0.32 0.44 0.14
186 INT159223 Binding of NR4A2 2 0.47 0.38 0.12
187 INT197289 Transcription of Nr4a2 1 0.06 0.06 0.12
188 INT179449 Binding of PDE1B 5 0.07 0.3 0.11
189 INT270973 Regulation of Protein_catabolism of Slc6a3 1 0.44 0 0.09
190 INT341783 Positive_regulation of Localization of SLC6A3 1 0.14 0.08 0.09
191 INT278552 Transcription of Tacr3 1 0.52 0 0.09
192 INT84940 Binding of Nr4a2 1 0.35 0.09 0.08
193 INT242947 Phosphorylation of PDE1B 1 0.02 0.11 0.08
194 INT100247 Positive_regulation of PDE1B 2 0.40 0.65 0.07
195 INT271054 Regulation of DRD4 1 0.12 0.61 0.07
196 INT276000 Negative_regulation of Positive_regulation of Pde1b 2 0.36 0.54 0.06
197 INT275994 Positive_regulation of Negative_regulation of Pde1b 1 0.43 0 0.06
198 INT246012 Negative_regulation of Gene_expression of Nr4a2 1 0.29 0.06 0.05
199 INT246014 Negative_regulation of Nr4a2 1 0.29 0 0.05
200 INT19234 Positive_regulation of Negative_regulation of PDE1B 1 0.01 0.05 0.04
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