GO:0042060

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Name wound healing
Categary Process
Go Slim No
Go Link GO:0042060
Unique Molecular Interactions 2280
Total Molecular Interactions 3052
Total Single Events 34544
Pain Genes Associated 120

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for wound healing. They are ordered first by their pain relevance and then by number of times they were reported for wound healing. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
4 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
5 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
6 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
7 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
8 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
9 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
10 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
11 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
12 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
13 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
14 INT70946 Penk Positive_regulation of Hpse 1 0.34 0 2.65
15 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
16 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
17 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
18 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
19 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
20 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
21 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
22 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
23 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
24 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
25 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
26 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
27 INT351380 Ngf Regulation of TPM1 1 0.44 2.17 2.11
28 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
29 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
30 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
31 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
32 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
33 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
34 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
35 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
36 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
37 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
38 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
39 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
40 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
41 INT108129 GDNF Regulation of Gene_expression of GRHL3 1 0.21 0.39 1.71
42 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69
43 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
44 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
45 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
46 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
47 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
48 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
49 INT24689 Binding of PLAT and Serpine1 1 0.00 3.77 1.64
50 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
51 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
52 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
53 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
54 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
55 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
56 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
57 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
58 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
59 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
60 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
61 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
62 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
63 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
64 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
65 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
66 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
67 INT75370 Positive_regulation of Binding of Hrh1 and RGD735065 1 0.00 0.56 1.41
68 INT75371 Binding of Hrh1 and RGD735065 1 0.00 0.55 1.4
69 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
70 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
71 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
72 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35
73 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
74 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
75 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
76 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
77 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29
78 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
79 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
80 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
81 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
82 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
83 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
84 INT8409 IL1A Positive_regulation of Positive_regulation of Vip 1 0.01 0.63 1.27
85 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
86 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
87 INT126801 Regulation of Binding of Oprm1 and Penk 1 0.34 0.4 1.25
88 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
89 INT136257 Tff3 Regulation of SGCG 1 0.00 0.18 1.24
90 INT202036 CAMK2N2 Negative_regulation of MMP3 1 0.00 0.73 1.24
91 INT136255 Tff3 Regulation of GRIA1 1 0.00 0.18 1.24
92 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
93 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
94 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
95 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
96 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
97 INT76165 IGKV2-30 Positive_regulation of Phosphorylation of Oprm1 1 0.00 0.08 1.22
98 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
99 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
100 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
101 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
102 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
103 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
104 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
105 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
106 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
107 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
108 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
109 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
110 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
111 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
112 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
113 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14
114 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
115 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
116 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
117 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
118 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
119 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
120 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
121 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
122 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
123 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
124 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
125 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
126 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07
127 INT87222 Nrg1 Regulation of Oprd1 1 0.00 0 1.07
128 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06
129 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06
130 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
131 INT116777 Psma5 Positive_regulation of Binding of Fn1 1 0.01 1.24 1.06
132 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
133 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05
134 INT8410 IL1A Positive_regulation of Vip 1 0.02 0.68 1.05
135 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
136 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
137 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
138 INT134213 CRH Positive_regulation of Gene_expression of ENG 1 0.13 0.61 1.03
139 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02
140 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
141 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 0.21 0.27 1.02
142 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
143 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
144 INT88884 IRF6 Regulation of Nos2 1 0.12 0.26 1
145 INT70105 SCD Positive_regulation of Oprm1 1 0.01 0 1
146 INT88886 IRF6 Positive_regulation of Nos2 1 0.22 0.26 1
147 INT88888 Regulation of IRF6 Positive_regulation of Nos2 1 0.20 0.26 1
148 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99
149 INT314037 THL Negative_regulation of Localization of Plau 1 0.17 1.64 0.99
150 INT95791 Binding of SSTR1 and GRHL3 1 0.38 0.57 0.99
151 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
152 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 0.05 0 0.99
153 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99
154 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
155 INT140168 Binding of Cx3cl1 and Cx3cr1 2 0.31 1.55 0.98
156 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
157 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
158 INT57555 Binding of Oprm1 and Oprl1 2 0.06 0.05 0.97
159 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
160 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97
161 INT40424 CCK Regulation of Localization of INS 1 0.02 0 0.97
162 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
163 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
164 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
165 INT240123 MIR885 Negative_regulation of IL1B 1 0.01 1.57 0.96
166 INT70947 Penk Regulation of Hpse 1 0.20 0 0.96
167 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96
168 INT130722 Binding of IL1B and Nfkb1 1 0.28 1.23 0.95
169 INT351311 Has1 Regulation of Gene_expression of MMP3 1 0.11 1.15 0.95
170 INT1654 Pomc Regulation of DSP 1 0.03 0 0.94
171 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
172 INT81919 Binding of HSF1 and IL1B 1 0.42 0.77 0.93
173 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
174 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
175 INT79123 Binding of Pnoc and Oprm1 3 0.14 0 0.91
176 INT32187 Binding of ENG and Negative_regulation of Localization of LH 1 0.01 0 0.91
177 INT250976 Binding of FMOD and IL8 1 0.08 1.26 0.91
178 INT66536 Il1a Regulation of Gene_expression of Fos 1 0.59 0 0.91
179 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91
180 INT13282 Fgf2 Regulation of Ngf 1 0.66 0.21 0.91
181 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
182 INT66334 Fgf2 Regulation of Fgf1 1 0.37 0.17 0.9
183 INT13280 Ngf Regulation of Fgf2 1 0.48 0.2 0.9
184 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
185 INT121704 HRAS Negative_regulation of MMP3 1 0.06 0.19 0.89
186 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
187 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89
188 INT83417 Binding of OPRL1 and Oprm1 1 0.01 0 0.89
189 INT97184 Oprm1 Regulation of Gene_expression of Pomc 1 0.31 0 0.89
190 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89
191 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
192 INT21944 Il1a Negative_regulation of Gnrh1 1 0.34 0 0.89
193 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
194 INT61048 Oprm1 Positive_regulation of Localization of Prl 1 0.16 0 0.88
195 INT108687 Nfkb1 Regulation of Positive_regulation of Nos2 1 0.50 1.28 0.88
196 INT136349 Il1b Positive_regulation of Positive_regulation of Oprl1 1 0.22 0.27 0.88
197 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
198 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
199 INT61045 Oprm1 Positive_regulation of Prl 1 0.16 0 0.88
200 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88

Single Events

The table below shows the top 100 pain related interactions that have been reported for wound healing. They are ordered first by their pain relevance and then by number of times they were reported in wound healing. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
2 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
3 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
4 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
5 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
6 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
7 INT812 Localization of INS 1026 0.81 515.6 145.31
8 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
9 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
10 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
11 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
12 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
13 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
14 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
15 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
16 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
17 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
18 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
19 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
20 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
21 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
22 INT6849 Localization of IL1B 229 0.81 112.56 69.63
23 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
24 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29
25 INT251 Regulation of INS 398 0.62 232.47 55.04
26 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
27 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
28 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
29 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
30 INT122041 Binding of Ppara 308 0.48 189.17 51.48
31 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
32 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
33 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
34 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
35 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
36 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
37 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78
38 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
39 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
40 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
41 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54
42 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
43 INT6484 Binding of IL1B 122 0.47 75.84 35.07
44 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
45 INT103094 Binding of PPARA 308 0.47 177.26 34.75
46 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6
47 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69
48 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
49 INT9347 Localization of Il1b 58 0.81 26.13 31.53
50 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
51 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
52 INT116737 Localization of Mif 63 0.81 52.97 28.11
53 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
54 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
55 INT10799 Localization of ENG 63 0.78 18.67 27.28
56 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9
57 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
58 INT5966 Localization of Il1a 50 0.78 22.91 26.54
59 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
60 INT13415 Positive_regulation of Hpse 58 0.70 24.9 25.53
61 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
62 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
63 INT93717 Gene_expression of Mmp3 85 0.78 33.95 24.89
64 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
65 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01
66 INT37889 Gene_expression of P2ry2 75 0.65 26.01 23.8
67 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
68 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54
69 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
70 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79
71 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6
72 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
73 INT614 Gene_expression of Cxcl2 29 0.76 25.53 20.8
74 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48
75 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
76 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
77 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86
78 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29
79 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19
80 INT12575 Regulation of Hpse 33 0.59 17.7 18.45
81 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24
82 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66
83 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
84 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
85 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78
86 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
87 INT61949 Regulation of Nos2 74 0.58 34.08 16.7
88 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17
89 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
90 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98
91 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
92 INT85964 Gene_expression of Pecam1 109 0.78 69.73 15.21
93 INT81486 Localization of MMP3 31 0.81 12.94 15.21
94 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12
95 INT12891 Negative_regulation of MMP3 41 0.58 17.99 15.06
96 INT170 Negative_regulation of Adrb1 52 0.55 13.46 14.78
97 INT61635 Positive_regulation of P2ry2 35 0.56 12.08 14.68
98 INT121162 Gene_expression of Cx3cl1 22 0.78 11.56 14.59
99 INT103096 Regulation of PPARA 113 0.60 62.47 14.57
100 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53
101 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
102 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49
103 INT7674 Regulation of ENG 42 0.30 11.41 14.44
104 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41
105 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
106 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98
107 INT55740 Gene_expression of Timp1 53 0.75 28.63 13.85
108 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
109 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67
110 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
111 INT69166 Positive_regulation of P2ry1 35 0.67 8.41 13.63
112 INT68814 Positive_regulation of Transcription of Oprm1 16 0.60 2.72 13.57
113 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4
114 INT14572 Binding of INS 205 0.48 175.43 13.38
115 INT95427 Positive_regulation of Mmp3 39 0.70 15.28 13.36
116 INT122037 Regulation of Ppara 93 0.62 56.28 12.89
117 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
118 INT3040 Gene_expression of MIA3 81 0.24 53.61 12.62
119 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61
120 INT60461 Positive_regulation of Gene_expression of Il1a 40 0.61 17.23 12.35
121 INT55687 Localization of TIMP1 47 0.74 30.24 12.31
122 INT32054 Gene_expression of Tnc 14 0.59 9.36 12.22
123 INT90673 Gene_expression of LOX 66 0.65 69.71 12.18
124 INT194462 Localization of Ppara 94 0.78 68.33 12.09
125 INT72949 Binding of Mif 31 0.46 23.12 11.65
126 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64
127 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58
128 INT82684 Positive_regulation of Pecam1 27 0.49 25.67 11.47
129 INT93122 Gene_expression of P2ry1 32 0.75 11.82 11.42
130 INT176607 Gene_expression of Cx3cl1 27 0.75 19.51 11.32
131 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15
132 INT6044 Regulation of Binding of Oprm1 16 0.61 3.01 11.11
133 INT59766 Positive_regulation of Negative_regulation of Oprm1 9 0.50 1.31 11.08
134 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
135 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
136 INT121161 Localization of Cx3cl1 14 0.75 10.07 10.61
137 INT94004 Negative_regulation of Lox 31 0.59 13.76 10.45
138 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
139 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
140 INT71592 Negative_regulation of Gene_expression of Oprm1 11 0.58 4.03 10.37
141 INT173159 Localization of PPARA 96 0.74 64.55 10.26
142 INT49474 Gene_expression of Hpse 24 0.55 20.11 10.03
143 INT61171 Gene_expression of S100A8 92 0.76 57.74 9.98
144 INT95794 Gene_expression of GRHL3 9 0.68 5.57 9.9
145 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
146 INT59 Regulation of Adrb1 25 0.42 8.32 9.78
147 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76
148 INT70850 Positive_regulation of Transcription of Nos2 30 0.70 18.95 9.68
149 INT105816 Gene_expression of P2RY2 53 0.78 16.47 9.67
150 INT102987 Regulation of MMP3 23 0.60 9.35 9.54
151 INT49483 Regulation of Positive_regulation of Oprm1 8 0.61 2.34 9.4
152 INT68133 Localization of Fgf2 36 0.81 15.37 9.14
153 INT82685 Gene_expression of Pecam1 36 0.76 27.95 9.01
154 INT30247 Regulation of Adrb1 18 0.44 4.45 8.93
155 INT29411 Positive_regulation of ADRB2 13 0.65 5.42 8.78
156 INT250978 Binding of FMOD 4 0.16 12.32 8.75
157 INT76162 Positive_regulation of Phosphorylation of Oprm1 11 0.69 0.64 8.72
158 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
159 INT7673 Negative_regulation of ENG 31 0.42 7.9 8.61
160 INT90674 Negative_regulation of LOX 56 0.57 38.01 8.58
161 INT97331 Positive_regulation of Timp1 20 0.45 13.32 8.57
162 INT96 Binding of Adrb1 18 0.48 2.8 8.52
163 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51
164 INT18021 Positive_regulation of Binding of Oprm1 16 0.70 2.53 8.38
165 INT127961 Transcription of GRHL3 1 0.45 4.34 8.17
166 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11
167 INT15725 Positive_regulation of Fn1 17 0.67 14.93 8.03
168 INT2271 Gene_expression of F2 51 0.76 30.21 7.97
169 INT113671 Negative_regulation of Mmp3 26 0.49 6.33 7.88
170 INT36678 Binding of TIMP1 33 0.36 14.99 7.87
171 INT26115 Gene_expression of Adrb1 14 0.64 5.13 7.78
172 INT98178 Localization of Casp3 32 0.65 21.01 7.77
173 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72
174 INT181817 Negative_regulation of Gene_expression of Ppara 58 0.58 43.24 7.67
175 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
176 INT23992 Positive_regulation of Adrb1 25 0.56 4.01 7.62
177 INT102351 Regulation of Pecam1 7 0.61 22.45 7.58
178 INT19475 Positive_regulation of IL1A 20 0.67 17.99 7.57
179 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53
180 INT85968 Positive_regulation of Pecam1 19 0.69 29.04 7.5
181 INT7883 Binding of ADRB2 18 0.47 5.49 7.37
182 INT76253 Positive_regulation of P2RY2 29 0.70 13.99 7.33
183 INT5308 Regulation of Il1a 17 0.44 10.8 7.31
184 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
185 INT43727 Negative_regulation of Gene_expression of MMP3 16 0.40 4.81 7.18
186 INT717 Regulation of F2 29 0.61 17.46 6.99
187 INT21579 Negative_regulation of Gene_expression of TIMP1 25 0.57 12.41 6.94
188 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
189 INT16628 Negative_regulation of Positive_regulation of Oprm1 9 0.43 0.89 6.92
190 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
191 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89
192 INT95466 Regulation of P2ry2 23 0.56 3.66 6.86
193 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84
194 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75
195 INT72532 Regulation of Gene_expression of Il1a 13 0.54 4.91 6.71
196 INT170922 Binding of Ppara 59 0.45 28.45 6.7
197 INT61114 Gene_expression of Ppard 23 0.75 14.98 6.62
198 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6
199 INT517 Regulation of Mif 16 0.62 5.43 6.55
200 INT3041 Positive_regulation of MIA3 34 0.56 21.11 6.49
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