GO:0042093

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Name T-helper cell differentiation
Categary Process
Go Slim No
Go Link GO:0042093
Unique Molecular Interactions 33
Total Molecular Interactions 37
Total Single Events 597
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for T-helper cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for T-helper cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182556 Ptger4 Positive_regulation of Ptgir 1 0.08 1.31 1.02
2 INT182567 Ptger4 Positive_regulation of Ptger1 1 0.15 1.31 1.02
3 INT209029 Il12b Positive_regulation of Elf1 1 0.24 0.37 0.72
4 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
5 INT209030 Il12b Positive_regulation of Cxcl1 1 0.16 0.37 0.72
6 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72
7 INT209032 Il12b Positive_regulation of Csf2 1 0.08 0.37 0.72
8 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57
9 INT342689 Ptger4 Positive_regulation of Prkaca 1 0.03 0.24 0.51
10 INT237778 Il12b Positive_regulation of Gene_expression of Eae1 1 0.01 1.51 0.39
11 INT217028 Adp Negative_regulation of Il12b 1 0.00 0 0.37
12 INT88068 Ptger2 Positive_regulation of Transcription of Ptger4 1 0.15 0 0.36
13 INT304320 Binding of Ptger2 and Ptger4 2 0.26 0.06 0.33
14 INT128934 Il1b Positive_regulation of Transcription of Ptger4 1 0.00 0 0.29
15 INT128933 Il1b Positive_regulation of Gene_expression of Ptger4 1 0.00 0 0.29
16 INT237380 Binding of Cdkn2d and Il12b 1 0.01 0.45 0.26
17 INT304321 Ptger4 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.59 0.23
18 INT304324 VEGFA Positive_regulation of Gene_expression of Ptger4 1 0.27 0.16 0.23
19 INT193214 Binding of PTGER2 and PTGER4 2 0.08 2.51 0.18
20 INT355882 TNF Positive_regulation of Gene_expression of Il12b 1 0.03 0.21 0.18
21 INT233386 Binding of Il12a and Il12b 1 0.01 0.48 0.15
22 INT237774 Il12b Positive_regulation of Eae1 1 0.01 0.58 0.13
23 INT253468 Ptger2 Positive_regulation of Ptger4 1 0.12 1.19 0.13
24 INT186375 TNF Negative_regulation of Gene_expression of Il12b 1 0.03 0.78 0.06
25 INT263337 Ptger4 Regulation of Ppara 1 0.02 0.3 0.04
26 INT331959 Binding of Ptger4 and Ptgfr 1 0.01 0.15 0.03
27 INT331963 Positive_regulation of Binding of Ptger4 and Ptgfr 1 0.01 0.15 0.03
28 INT302171 PTGER4 Positive_regulation of RASGRP1 1 0.01 1.03 0.03
29 INT233387 Binding of SPINK1 and Il12b 1 0.04 0.33 0
30 INT344893 Binding of ADCY1 and Ptger4 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for T-helper cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in T-helper cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68
2 INT68960 Gene_expression of Ptger4 42 0.67 15.75 9.64
3 INT80712 Gene_expression of PTGER4 21 0.65 13.08 5.03
4 INT88062 Gene_expression of Ptger4 13 0.77 2.4 4.94
5 INT88059 Positive_regulation of Ptger4 9 0.69 1.41 4.4
6 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89
7 INT144231 Gene_expression of Il12b 18 0.75 12.93 3.65
8 INT133169 Positive_regulation of Il12b 25 0.49 13 3.64
9 INT119470 Regulation of Ptger4 6 0.43 3.94 3.24
10 INT133174 Positive_regulation of Gene_expression of Il12b 29 0.15 13.04 2.92
11 INT68962 Positive_regulation of Ptger4 20 0.67 7.3 2.79
12 INT92648 Positive_regulation of IL12B 7 0.20 4.55 2.19
13 INT94615 Localization of Ptger4 5 0.28 0.35 2.13
14 INT74156 Positive_regulation of Il12b 3 0.49 1.54 2.04
15 INT92056 Transcription of Il12b 8 0.69 4.75 1.95
16 INT133170 Negative_regulation of Il12b 12 0.05 5.32 1.86
17 INT169786 Localization of Ptger4 7 0.69 1.82 1.65
18 INT174230 Positive_regulation of Gene_expression of IL12B 6 0.49 3.2 1.56
19 INT97142 Localization of IL12B 5 0.73 1.73 1.46
20 INT131188 Negative_regulation of Gene_expression of PTGER4 1 0.41 2.51 1.41
21 INT296755 Positive_regulation of Gene_expression of PTGER4 2 0.33 2.03 1.34
22 INT140877 Regulation of Ptger4 6 0.36 2.2 1.23
23 INT236329 Regulation of IL12B 3 0.02 0.78 1.2
24 INT88063 Binding of Ptger4 2 0.37 0.35 1.2
25 INT92055 Positive_regulation of Transcription of Il12b 4 0.49 2.77 1.16
26 INT233357 Localization of Il12b 7 0.16 3.4 1.12
27 INT144232 Negative_regulation of Gene_expression of Il12b 4 0.41 2.26 1.01
28 INT193256 Positive_regulation of PTGER4 6 0.19 4.38 0.99
29 INT233349 Regulation of Il12b 5 0.05 3.71 0.98
30 INT133173 Regulation of Negative_regulation of Il12b 2 0.04 0.52 0.97
31 INT92649 Negative_regulation of Gene_expression of IL12B 3 0.03 2.23 0.86
32 INT169788 Negative_regulation of Ptger4 5 0.51 2.11 0.82
33 INT169792 Positive_regulation of Gene_expression of Ptger4 5 0.60 2 0.82
34 INT88067 Negative_regulation of Positive_regulation of Ptger4 2 0.58 0.3 0.75
35 INT77591 Binding of Ptger4 3 0.36 1.09 0.74
36 INT186283 Negative_regulation of Gene_expression of Il12b 2 0.13 7.92 0.74
37 INT131186 Negative_regulation of PTGER4 2 0.41 2.97 0.74
38 INT169790 Negative_regulation of Localization of Ptger4 1 0.37 0.77 0.72
39 INT169784 Regulation of Localization of Ptger4 1 0.39 0.77 0.72
40 INT88061 Positive_regulation of Gene_expression of Ptger4 1 0.69 0 0.67
41 INT74155 Transcription of Il12b 3 0.60 1.45 0.66
42 INT156544 Regulation of Il12b 2 0.44 1.29 0.66
43 INT88066 Transcription of Ptger4 2 0.71 0 0.64
44 INT186277 Binding of Il12b 4 0.20 2.15 0.55
45 INT86132 Transcription of Ptger4 4 0.47 0.85 0.49
46 INT330393 Positive_regulation of Gene_expression of Il12b 2 0.49 1.24 0.48
47 INT113653 Regulation of Gene_expression of Ptger4 1 0.30 0.19 0.44
48 INT233355 Positive_regulation of Localization of Il12b 2 0.11 0.99 0.43
49 INT185318 Negative_regulation of Transcription of Il12b 2 0.06 1.03 0.43
50 INT233356 Negative_regulation of Positive_regulation of Il12b 3 0.13 0.85 0.38
51 INT193255 Transcription of PTGER4 2 0.19 1.4 0.38
52 INT68965 Positive_regulation of Positive_regulation of Ptger4 3 0.43 1.43 0.37
53 INT233350 Regulation of Gene_expression of Il12b 1 0.06 3.03 0.37
54 INT92652 Negative_regulation of Positive_regulation of IL12B 1 0.03 0.99 0.36
55 INT128931 Negative_regulation of Gene_expression of Ptger4 1 0.01 0 0.36
56 INT88064 Positive_regulation of Transcription of Ptger4 1 0.50 0 0.36
57 INT348183 Binding of IL12B 1 0.46 0.97 0.33
58 INT146534 Regulation of PTGER4 1 0.02 0.35 0.33
59 INT88060 Positive_regulation of Positive_regulation of Ptger4 1 0.46 0 0.3
60 INT304318 Negative_regulation of Gene_expression of Ptger4 1 0.34 0 0.29
61 INT329823 Negative_regulation of Il12b 1 0.42 0.57 0.27
62 INT294675 Localization of Il12b 2 0.78 1.15 0.19
63 INT119167 Positive_regulation of Transcription of Il12b 1 0.09 0.77 0.17
64 INT237761 Phosphorylation of Il12b 1 0.09 0.49 0.11
65 INT233354 Positive_regulation of Positive_regulation of Il12b 1 0.06 2.91 0.07
66 INT186310 Positive_regulation of Binding of Il12b 1 0.15 1.07 0.07
67 INT97135 Positive_regulation of Localization of IL12B 2 0.49 0.92 0.05
68 INT263333 Regulation of Gene_expression of Ptger4 1 0.15 0.3 0.04
69 INT302250 Localization of PTGER4 1 0.20 0.79 0.03
70 INT305355 Transcription of IL12B 1 0.52 0.46 0.03
71 INT344887 Negative_regulation of Binding of Ptger4 1 0.28 0 0
72 INT302269 Phosphorylation of PTGER4 1 0.17 0.75 0
73 INT97143 Regulation of Localization of IL12B 1 0.08 0 0
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