GO:0042110

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Name T cell activation
Categary Process
Go Slim No
Go Link GO:0042110
Unique Molecular Interactions 1739
Total Molecular Interactions 2497
Total Single Events 19629
Pain Genes Associated 57

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for T cell activation. They are ordered first by their pain relevance and then by number of times they were reported for T cell activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73
2 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09
3 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
4 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
5 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
6 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22
7 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
8 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
9 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12
10 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
11 INT42728 Binding of PRLR and Cpe 1 0.00 0 2.91
12 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
13 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
14 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76
15 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
16 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
17 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
18 INT299783 Binding of Cd28 and Cd80 7 0.14 6.49 2.49
19 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
20 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
21 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
22 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
23 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21
24 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
25 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
26 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
27 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
28 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14
29 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13
30 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
31 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
32 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
33 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
34 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
35 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
36 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
37 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
38 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
39 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
40 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
41 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
42 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
43 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
44 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
45 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
46 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
47 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
48 INT201950 IFNA1 Positive_regulation of Binding of DPP4 1 0.12 2.17 1.47
49 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
50 INT201946 IFNA1 Positive_regulation of DPP4 1 0.17 2.16 1.46
51 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
52 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
53 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
54 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
55 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
56 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
57 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
58 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
59 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
60 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31
61 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
62 INT201942 DPP4 Negative_regulation of CXCL10 1 0.33 0.9 1.3
63 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27
64 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
65 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
66 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
67 INT285185 Binding of Ca2 and Cd2 1 0.25 0.24 1.21
68 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
69 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
70 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
71 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
72 INT212815 WAS Positive_regulation of CNR1 1 0.01 0.62 1.16
73 INT212824 WAS Positive_regulation of Cnr1 1 0.21 0.62 1.16
74 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
75 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
76 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
77 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
78 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
79 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
80 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
81 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
82 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
83 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
84 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
85 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
86 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
87 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06
88 INT239038 Negative_regulation of Binding of Cd28 and Cd86 3 0.17 1.5 1.05
89 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
90 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
91 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
92 INT338894 TNFSF14 Negative_regulation of Gsk3a 1 0.00 0.54 1.04
93 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
94 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
95 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
96 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
97 INT338892 TNFSF14 Regulation of Abat 1 0.00 0.61 1.01
98 INT131173 Chrna7 Positive_regulation of Localization of Abat 1 0.10 0 1.01
99 INT338895 TNFSF14 Regulation of Regulation of Abat 1 0.00 0.62 1.01
100 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
101 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
102 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
103 INT103928 Binding of Cd28 and Trav6-3 3 0.03 0.55 0.98
104 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
105 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
106 INT272984 Il6 Positive_regulation of Gene_expression of Itgam 1 0.24 0.78 0.96
107 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
108 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
109 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
110 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
111 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
112 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93
113 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
114 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
115 INT34271 Positive_regulation of WAS Positive_regulation of Oprd1 1 0.01 0 0.91
116 INT34273 WAS Regulation of Oprd1 1 0.00 0 0.91
117 INT34272 WAS Positive_regulation of Oprd1 1 0.01 0 0.91
118 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
119 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
120 INT91270 Oprd1 Regulation of Gene_expression of Il6 1 0.00 0 0.89
121 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
122 INT91273 Mtr Positive_regulation of Localization of Il6 1 0.17 0 0.88
123 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
124 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
125 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
126 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
127 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
128 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
129 INT76652 Cpe Positive_regulation of Il6 1 0.08 0 0.87
130 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86
131 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
132 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
133 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86
134 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85
135 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
136 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84
137 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
138 INT174509 Binding of CD4 and CD28 1 0.26 1.68 0.84
139 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
140 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
141 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
142 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
143 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
144 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
145 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
146 INT188567 IRF6 Positive_regulation of Gene_expression of CD28 1 0.05 1.28 0.82
147 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
148 INT53199 Positive_regulation of Cd4 Positive_regulation of Gene_expression of Il2 1 0.52 0.72 0.8
149 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
150 INT135278 Gt(pU21)50Imeg Negative_regulation of Positive_regulation of Il6 1 0.02 0.26 0.8
151 INT160411 Tat Positive_regulation of Il6 1 0.17 0.89 0.8
152 INT140921 Btnl2 Negative_regulation of Cd4 1 0.01 0.88 0.8
153 INT117971 Cd8a Negative_regulation of Positive_regulation of Ephb1 1 0.02 0.98 0.79
154 INT135277 Gt(pU21)50Imeg Negative_regulation of Il6 1 0.02 0.23 0.78
155 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
156 INT84466 DPP4 Regulation of Localization of Naga 1 0.00 0.87 0.78
157 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
158 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
159 INT23681 Negative_regulation of Binding of Stx3 and Chrna7 1 0.00 0 0.75
160 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
161 INT23680 Binding of Stx3 and Chrna7 1 0.00 0 0.75
162 INT201947 IFNA1 Positive_regulation of Gene_expression of DPP4 1 0.11 1.09 0.74
163 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
164 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
165 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
166 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
167 INT124352 Il6 Positive_regulation of Positive_regulation of Gorasp2 1 0.10 1.19 0.73
168 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73
169 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72
170 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
171 INT237325 Il6 Positive_regulation of Gene_expression of Ik 2 0.00 2.09 0.72
172 INT209057 Il6 Positive_regulation of Csf2 1 0.03 0.38 0.72
173 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72
174 INT209039 Il6 Positive_regulation of Il17a 1 0.05 0.38 0.72
175 INT209056 Il6 Positive_regulation of Elf1 1 0.10 0.38 0.72
176 INT209059 Il6 Positive_regulation of Cxcl1 1 0.06 0.38 0.72
177 INT150996 Sfpq Positive_regulation of Gene_expression of Il6 1 0.04 0.7 0.72
178 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
179 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
180 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72
181 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
182 INT260551 Igh-Dex Negative_regulation of Il6 1 0.09 0.37 0.72
183 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
184 INT139069 Binding of CTLA4 and Cd86 3 0.16 0.65 0.7
185 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
186 INT209956 Binding of CD8A and RDBP 1 0.01 0.3 0.7
187 INT91700 Il6 Negative_regulation of Oprd1 1 0.23 0 0.7
188 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
189 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
190 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
191 INT150998 Sfpq Negative_regulation of Gene_expression of Il6 1 0.05 0.69 0.69
192 INT325270 Il33 Positive_regulation of Gene_expression of Il6 1 0.20 1.59 0.69
193 INT76655 POMC Positive_regulation of Transcription of Il6 1 0.01 0 0.68
194 INT76654 Cpe Positive_regulation of Transcription of Il6 1 0.05 0 0.68
195 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
196 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
197 INT102350 P2rx1 Negative_regulation of Localization of Il6 1 0.32 0 0.67
198 INT164782 Il6 Regulation of Gene_expression of Cx3cr1 1 0.27 0.79 0.67
199 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
200 INT82384 Penk Positive_regulation of Gene_expression of Il6 1 0.15 0 0.66

Single Events

The table below shows the top 100 pain related interactions that have been reported for T cell activation. They are ordered first by their pain relevance and then by number of times they were reported in T cell activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
3 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
4 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
5 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
6 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
7 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
8 INT12082 Localization of IL6 365 0.81 241.78 105.78
9 INT19511 Localization of Il6 212 0.81 118.17 67.67
10 INT11937 Localization of Il6 228 0.81 139.83 64.39
11 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
12 INT10706 Regulation of Il6 150 0.62 93.23 62.34
13 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
14 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
15 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
16 INT9210 Regulation of IL6 166 0.62 125.61 49.95
17 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
18 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
19 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
20 INT23330 Binding of Chrna7 79 0.48 10.06 35.5
21 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05
22 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
23 INT9655 Regulation of Il6 98 0.62 70.92 31.95
24 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
25 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
26 INT86437 Binding of IL6 154 0.48 121.22 29.3
27 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
28 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39
29 INT51474 Binding of Il6 55 0.48 44.99 20.52
30 INT49985 Transcription of Il6 62 0.72 40.13 20.29
31 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44
32 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
33 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
34 INT61626 Transcription of IL6 73 0.72 42.04 17.86
35 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
36 INT84464 Gene_expression of DPP4 101 0.78 56.15 17.53
37 INT96155 Gene_expression of Cd86 134 0.77 50.56 17.13
38 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43
39 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
40 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
41 INT49376 Negative_regulation of Localization of Il6 37 0.59 12.66 14.99
42 INT32802 Negative_regulation of Ada 21 0.57 4.03 14.87
43 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
44 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
45 INT171134 Gene_expression of CD28 67 0.65 32.55 13.61
46 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15
47 INT132178 Binding of CD80 41 0.47 15.55 12.98
48 INT54763 Binding of Il6 82 0.48 63.27 12.89
49 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
50 INT52905 Gene_expression of Cd4 84 0.78 45.68 12.75
51 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
52 INT87698 Gene_expression of WAS 25 0.58 8.75 11.83
53 INT50933 Transcription of Il6 38 0.72 24.31 11.58
54 INT80756 Gene_expression of CD86 77 0.77 46.68 11.36
55 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
56 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
57 INT11794 Gene_expression of Cd2 27 0.76 17.31 10.99
58 INT23675 Negative_regulation of Binding of Chrna7 18 0.37 0.5 10.74
59 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59
60 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38
61 INT10019 Binding of CD8A 57 0.36 31.49 10.08
62 INT73504 Binding of CD28 35 0.45 15.99 10.04
63 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98
64 INT19620 Binding of CD86 30 0.47 12.01 9.89
65 INT12367 Binding of PRLR 17 0.03 2.05 9.69
66 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51
67 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51
68 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
69 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
70 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97
71 INT34268 Binding of WAS 14 0.47 4.41 8.67
72 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51
73 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
74 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25
75 INT87699 Positive_regulation of WAS 16 0.45 5.84 8.03
76 INT4663 Positive_regulation of Ada 17 0.69 9.48 7.93
77 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76
78 INT94125 Gene_expression of Cd28 38 0.67 21.73 7.75
79 INT93914 Gene_expression of CD80 70 0.75 36.35 7.74
80 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53
81 INT81378 Negative_regulation of Dpp4 18 0.59 7.87 7.42
82 INT120401 Positive_regulation of PIK3CD 33 0.45 14.89 7.37
83 INT18909 Positive_regulation of Cd8a 92 0.60 56.55 7.35
84 INT33105 Regulation of WAS 11 0.60 3.61 7.18
85 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
86 INT160562 Localization of Cd4 49 0.71 27.58 6.78
87 INT50255 Regulation of Cd4 39 0.49 29.73 6.77
88 INT13139 Negative_regulation of Cd4 27 0.47 17.49 6.61
89 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42
90 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
91 INT53196 Binding of Cd4 44 0.47 27.28 5.85
92 INT56149 Localization of CD8A 56 0.74 30.41 5.75
93 INT29674 Gene_expression of Ada 16 0.78 4.59 5.69
94 INT30206 Negative_regulation of ADA 17 0.59 10.03 5.63
95 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
96 INT64716 Regulation of Positive_regulation of Il6 7 0.54 2.83 5.34
97 INT16405 Regulation of CD8A 38 0.45 19.04 5.31
98 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25
99 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
100 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
101 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18
102 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
103 INT49375 Regulation of Localization of Il6 16 0.62 4.54 5.08
104 INT95131 Binding of Cd4 27 0.37 21.62 5.07
105 INT36256 Regulation of Ada 9 0.62 4.99 5.07
106 INT9767 Negative_regulation of Ada 5 0.55 0.06 5.06
107 INT15131 Gene_expression of CD2 20 0.75 9.47 5.01
108 INT26583 Positive_regulation of Cd4 40 0.54 21.96 4.83
109 INT13313 Regulation of PRLR 7 0.07 1.65 4.77
110 INT118274 Positive_regulation of Positive_regulation of PIK3CG 8 0.64 4.81 4.62
111 INT135990 Positive_regulation of Gene_expression of Cd86 34 0.69 12.02 4.53
112 INT64653 Binding of CD2 17 0.44 6.74 4.45
113 INT52133 Regulation of Localization of Il6 7 0.61 5.35 4.37
114 INT116902 Positive_regulation of CD28 17 0.47 13.56 4.27
115 INT110343 Negative_regulation of PIK3CD 22 0.40 5.84 4.2
116 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
117 INT110348 Negative_regulation of Dpp4 28 0.46 22.39 4.12
118 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
119 INT86919 Negative_regulation of PIK3CG 40 0.57 21.16 3.97
120 INT134590 Localization of ADA 7 0.65 8.43 3.96
121 INT48456 Localization of WAS 6 0.56 1.63 3.95
122 INT4649 Positive_regulation of Chrna7 17 0.50 5.48 3.92
123 INT73981 Gene_expression of Hspd1 18 0.75 5.69 3.72
124 INT44717 Gene_expression of TNFSF14 12 0.75 13.44 3.72
125 INT140337 Negative_regulation of Cd8a 42 0.50 25.4 3.66
126 INT64030 Gene_expression of Cd8a 15 0.56 4.8 3.63
127 INT13451 Positive_regulation of DPP4 23 0.68 9.33 3.62
128 INT44015 Binding of Cd86 16 0.31 5.92 3.58
129 INT66924 Positive_regulation of Transcription of Il6 18 0.68 11.8 3.53
130 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
131 INT18825 Gene_expression of PRLR 8 0.40 2 3.47
132 INT201959 Positive_regulation of Gene_expression of DPP4 13 0.53 6.24 3.4
133 INT72798 Binding of ADA 12 0.47 7.84 3.39
134 INT188355 Binding of Cd28 25 0.34 8.29 3.38
135 INT81403 Positive_regulation of Regulation of Il6 4 0.44 1.81 3.37
136 INT64715 Phosphorylation of Il6 7 0.81 4.24 3.36
137 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
138 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
139 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
140 INT19392 Gene_expression of Ada 9 0.77 7.4 3.17
141 INT82444 Positive_regulation of Gene_expression of Cd4 10 0.47 4.36 3.12
142 INT34604 Binding of Ada 11 0.31 4.15 3.1
143 INT9766 Positive_regulation of Ada 2 0.47 0.4 3.09
144 INT105297 Negative_regulation of Regulation of WAS 3 0.28 0.98 3.07
145 INT94947 Positive_regulation of Transcription of Il6 9 0.67 6.91 3.04
146 INT20082 Positive_regulation of PRLR 6 0.29 4.27 3.03
147 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
148 INT131494 Regulation of ADA 8 0.52 7.37 2.97
149 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
150 INT201952 Binding of DPP4 11 0.37 8.81 2.91
151 INT155486 Positive_regulation of Gene_expression of CD86 16 0.69 14.6 2.86
152 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
153 INT64714 Positive_regulation of Phosphorylation of Il6 4 0.50 3.22 2.67
154 INT75685 Regulation of CD86 12 0.58 3.55 2.66
155 INT174527 Negative_regulation of CD28 13 0.35 5.06 2.65
156 INT25646 Negative_regulation of PRLR 5 0.08 0.08 2.62
157 INT174687 Regulation of Positive_regulation of Il6 10 0.61 9.07 2.61
158 INT19621 Positive_regulation of CD86 23 0.69 14 2.58
159 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56
160 INT81377 Gene_expression of Dpp4 8 0.71 5.15 2.51
161 INT61805 Positive_regulation of Dpp4 4 0.44 0.41 2.49
162 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
163 INT15127 Regulation of Cd2 4 0.44 1.06 2.38
164 INT96154 Negative_regulation of Gene_expression of Cd86 10 0.48 3.76 2.35
165 INT34266 Negative_regulation of Binding of PRLR 3 0.01 0 2.35
166 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
167 INT84465 Localization of DPP4 8 0.75 7.28 2.29
168 INT144652 Negative_regulation of Binding of CD28 6 0.55 3.09 2.28
169 INT34796 Positive_regulation of TNFSF14 7 0.67 4.16 2.26
170 INT81312 Positive_regulation of Gene_expression of Ada 2 0.50 1.58 2.26
171 INT27880 Positive_regulation of HSPD1 17 0.65 18.16 2.23
172 INT152436 Positive_regulation of Gene_expression of HSPD1 12 0.67 10.06 2.16
173 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
174 INT24196 Positive_regulation of Binding of Chrna7 8 0.45 0.79 2.13
175 INT264967 Positive_regulation of Positive_regulation of PIK3CD 4 0.18 1.97 2.13
176 INT17747 Regulation of Cd4 14 0.41 10.02 2.12
177 INT97134 Negative_regulation of CD80 8 0.57 5.09 2.11
178 INT20373 Localization of Cd8a 28 0.64 8.22 2.07
179 INT52197 Negative_regulation of Transcription of Il6 8 0.43 3.8 2.05
180 INT54234 Binding of Cd2 6 0.35 2.14 1.99
181 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98
182 INT58691 Positive_regulation of Gene_expression of CD8A 26 0.50 15.19 1.97
183 INT167035 Regulation of Cd8a 25 0.41 16.78 1.9
184 INT61806 Regulation of Negative_regulation of Ada 1 0.30 0.63 1.89
185 INT93912 Positive_regulation of CD80 11 0.56 7.01 1.88
186 INT47425 Localization of Chrna7 11 0.81 6.7 1.86
187 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
188 INT36018 Negative_regulation of Gene_expression of CD8A 12 0.42 6.66 1.85
189 INT111675 Regulation of TNFSF14 3 0.26 3.41 1.85
190 INT174511 Positive_regulation of Gene_expression of CD28 7 0.41 4.31 1.83
191 INT8787 Negative_regulation of WAS 4 0.42 2.42 1.81
192 INT228401 Positive_regulation of Cd86 24 0.53 6.46 1.8
193 INT27881 Binding of HSPD1 10 0.31 9.2 1.78
194 INT19617 Negative_regulation of CD86 12 0.42 3.68 1.77
195 INT97621 Negative_regulation of Cd8a 3 0.24 3.08 1.77
196 INT155455 Negative_regulation of Phosphorylation of Il6 1 0.31 2.5 1.76
197 INT147636 Regulation of CD80 3 0.60 1.27 1.73
198 INT181523 Gene_expression of Ifnar1 16 0.67 7.79 1.72
199 INT221426 Positive_regulation of Gene_expression of FOXP3 9 0.48 5.98 1.72
200 INT135275 Regulation of Negative_regulation of Il6 4 0.45 0.89 1.67
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