GO:0042118

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Name endothelial cell activation
Categary Process
Go Slim No
Go Link GO:0042118
Unique Molecular Interactions 13
Total Molecular Interactions 15
Total Single Events 94
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for endothelial cell activation. They are ordered first by their pain relevance and then by number of times they were reported for endothelial cell activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT148452 Inhbe Regulation of Acvrl1 1 0.01 0.69 0.69
2 INT146276 Binding of P2RX4 and P2RX7 1 0.38 0.38 0.43
3 INT158708 Positive_regulation of P2RX4 Positive_regulation of Localization of Bdnf 1 0.09 0.48 0.3
4 INT158707 P2RX4 Positive_regulation of Localization of Bdnf 1 0.40 0.59 0.29
5 INT165171 Tpsab1 Positive_regulation of Gene_expression of P2RX4 1 0.02 0.47 0.28
6 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
7 INT311900 Acvrl1 Negative_regulation of Insrr 1 0.00 0.86 0.25
8 INT311908 Acvrl1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
9 INT311903 Acvrl1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
10 INT311910 Acvrl1 Positive_regulation of Phosphorylation of Smad1 1 0.12 0.24 0.06
11 INT310187 Acvrl1 Regulation of Gene_expression of Bmpr2 1 0.04 0 0
12 INT310189 Binding of Acvrl1 and Gdf2 1 0.01 0 0
13 INT310192 Tgfbr1 Positive_regulation of Regulation of Acvrl1 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for endothelial cell activation. They are ordered first by their pain relevance and then by number of times they were reported in endothelial cell activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98329 Gene_expression of P2RX4 23 0.75 13.13 10.25
2 INT158603 Positive_regulation of Gene_expression of P2RX4 7 0.55 5.85 4.56
3 INT136179 Positive_regulation of P2RX4 9 0.67 7.06 4.27
4 INT158602 Regulation of P2RX4 3 0.48 2.46 1.7
5 INT310167 Gene_expression of Acvrl1 2 0.40 5.47 1.4
6 INT146616 Localization of P2RX4 3 0.68 1.65 0.96
7 INT311884 Negative_regulation of Acvrl1 1 0.30 2.16 0.81
8 INT146277 Binding of P2RX4 5 0.45 1.1 0.79
9 INT265328 Positive_regulation of Acvrl1 5 0.40 3.18 0.78
10 INT216509 Negative_regulation of Positive_regulation of P2RX4 1 0.34 1.12 0.73
11 INT136594 Negative_regulation of P2RX4 1 0.57 1.16 0.7
12 INT278118 Positive_regulation of Positive_regulation of P2RX4 1 0.16 0.59 0.49
13 INT311889 Negative_regulation of Gene_expression of Acvrl1 1 0.22 1.27 0.37
14 INT311895 Regulation of Positive_regulation of Acvrl1 1 0.23 0.97 0.29
15 INT146279 Negative_regulation of Gene_expression of P2RX4 2 0.46 0.33 0.28
16 INT158704 Regulation of Localization of P2RX4 1 0.13 0.42 0.25
17 INT217015 Transcription of P2RX4 1 0.20 0.05 0.15
18 INT210224 Localization of Acvrl1 1 0.03 0.33 0.12
19 INT265340 Binding of Acvrl1 3 0.30 0.46 0
20 INT310166 Regulation of Acvrl1 1 0.07 0 0
21 INT310163 Positive_regulation of Positive_regulation of Acvrl1 1 0.08 0 0
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