GO:0042157

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Name lipoprotein metabolic process
Categary Process
Go Slim No
Go Link GO:0042157
Unique Molecular Interactions 851
Total Molecular Interactions 1147
Total Single Events 12497
Pain Genes Associated 47

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for lipoprotein metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for lipoprotein metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
2 INT66157 Binding of ALB and BDP1 1 0.11 0 2.13
3 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53
4 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32
5 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
6 INT19535 Binding of ADRA1D and ALB 3 0.42 0.8 1.15
7 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14
8 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14
9 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
10 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 0.30 0.38 0.99
11 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99
12 INT73680 KNG1 Positive_regulation of ALB 1 0.51 0.38 0.98
13 INT156989 LPA Positive_regulation of Gene_expression of EFNB1 1 0.00 0.91 0.92
14 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
15 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
16 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88
17 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
18 INT218037 Binding of ALB and Penk 1 0.13 0 0.81
19 INT110726 Binding of ALB and LTF 1 0.01 0 0.81
20 INT16507 Binding of LPA and Crp 1 0.00 0.78 0.78
21 INT16494 Binding of LPA and Serpinf2 1 0.00 0.78 0.78
22 INT351364 LPA Positive_regulation of Trpv1 1 0.02 1.15 0.78
23 INT16492 Positive_regulation of Binding of LPA and Serpinf2 1 0.00 0.78 0.78
24 INT16506 Positive_regulation of Binding of LPA and Crp 1 0.00 0.78 0.78
25 INT16498 Binding of ADRA1D and LPA 1 0.10 0.78 0.78
26 INT16497 Positive_regulation of Binding of ADRA1D and LPA 1 0.10 0.78 0.78
27 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
28 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
29 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
30 INT209859 IL4 Positive_regulation of PPARA 1 0.22 1.66 0.69
31 INT351367 LPA Regulation of Trpv1 1 0.01 0.83 0.69
32 INT335054 LPL Positive_regulation of Localization of VLDLR 1 0.04 1.48 0.67
33 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
34 INT92045 Binding of ALB and SERPINA1 1 0.30 1.37 0.64
35 INT167795 Negative_regulation of LPA Negative_regulation of Mag 1 0.01 0.84 0.64
36 INT114950 YY1 Positive_regulation of Positive_regulation of PPARA 1 0.52 0.25 0.64
37 INT167794 LPA Negative_regulation of Mag 1 0.01 0.77 0.63
38 INT114948 NCOA1 Positive_regulation of Positive_regulation of PPARA 1 0.20 0.24 0.62
39 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
40 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
41 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
42 INT50883 Binding of AGTR2 and ALB 1 0.37 0.19 0.56
43 INT139429 LPA Positive_regulation of Negative_regulation of MBP 1 0.00 0.78 0.56
44 INT544 Binding of ALB and GC 1 0.13 0 0.55
45 INT114029 Binding of ALB and Mmp3 1 0.01 0.31 0.55
46 INT351581 Binding of ALB and GOPC 1 0.11 0 0.55
47 INT114028 Negative_regulation of Binding of ALB and Mmp3 1 0.01 0.31 0.55
48 INT351365 LPA Positive_regulation of Localization of Il6 1 0.00 1.79 0.54
49 INT125086 LPA Positive_regulation of Rtn4 1 0.00 0.36 0.54
50 INT211993 Binding of Ppara and Rorb 1 0.00 1.13 0.54
51 INT103092 Binding of PPARA and ISYNA1 1 0.01 0.45 0.54
52 INT223934 HSPG2 Negative_regulation of Gene_expression of Cux1 1 0.03 0 0.53
53 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
54 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
55 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
56 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
57 INT120384 PRKCD Positive_regulation of Localization of HSPG2 1 0.29 0.42 0.51
58 INT167583 ENPP2 Positive_regulation of Gene_expression of LPA 1 0.08 0.93 0.51
59 INT334901 LDLR Positive_regulation of Crp 1 0.00 1.48 0.51
60 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
61 INT27730 Binding of ALB and Shbg 2 0.01 0.44 0.5
62 INT285688 Cpox Positive_regulation of PPARA 1 0.02 1 0.5
63 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
64 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
65 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
66 INT88889 Binding of HSPG2 and CALCRL 1 0.00 0 0.48
67 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48
68 INT137416 Binding of SDC1 and Tnf 1 0.00 1.19 0.47
69 INT240441 Ltb4r1 Positive_regulation of PPARA 1 0.03 1.01 0.47
70 INT173293 LPA Positive_regulation of OR1S1 1 0.03 0.15 0.47
71 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
72 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
73 INT240442 Binding of PPARA and Ltb4r1 1 0.02 0.94 0.46
74 INT223936 HSPG2 Positive_regulation of Gene_expression of Cux1 1 0.03 0 0.46
75 INT136749 COX5A Positive_regulation of Gene_expression of SCARB1 1 0.52 0.36 0.45
76 INT223935 HSPG2 Positive_regulation of Cux1 1 0.03 0 0.45
77 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
78 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
79 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43
80 INT54135 Binding of F13A1 and LPA 2 0.00 0.71 0.42
81 INT54136 Negative_regulation of Binding of F13A1 and LPA 1 0.00 0.42 0.42
82 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
83 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42
84 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
85 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
86 INT248242 Binding of COL7A1 and SDC1 1 0.00 0.76 0.41
87 INT248236 Binding of FN1 and SDC1 1 0.00 0.76 0.41
88 INT46225 Binding of ALB and POMC 1 0.36 0 0.4
89 INT38269 Binding of TCN1 and CUBN 1 0.00 0.28 0.4
90 INT251015 OLR1 Regulation of Protein_catabolism of MMP3 1 0.03 0.91 0.4
91 INT238382 Il13 Positive_regulation of Gene_expression of Ppara 1 0.18 0.79 0.4
92 INT107706 PPARA Positive_regulation of Gene_expression of CPOX 1 0.18 0.14 0.4
93 INT236110 Binding of Ppara and Olfm4 1 0.00 1.22 0.4
94 INT236111 Binding of Pdpk1 and Ppara 1 0.26 1.21 0.39
95 INT297423 Gene_expression of Il4 Regulation of Ppara 1 0.07 1.19 0.38
96 INT297424 Gene_expression of Stat6 Regulation of Ppara 1 0.17 1.19 0.38
97 INT297425 Il4 Regulation of Ppara 1 0.07 1.17 0.38
98 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
99 INT297426 Stat6 Regulation of Ppara 1 0.17 1.19 0.38
100 INT43956 GCG Regulation of ALB 1 0.16 0.15 0.38
101 INT235432 Ppara Negative_regulation of Gene_expression of Cpox 1 0.01 1 0.37
102 INT221814 Mastl Positive_regulation of Ppara 1 0.04 0.68 0.37
103 INT316672 Binding of LRP1 and SFTPD 1 0.35 0.96 0.37
104 INT297352 KLF2 Regulation of PPARA 1 0.12 1.31 0.35
105 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34
106 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
107 INT297351 EWSR1 Positive_regulation of PPARA 1 0.41 1.81 0.33
108 INT240434 PPARA Negative_regulation of Gene_expression of CPOX 1 0.03 0.64 0.33
109 INT235430 Il13 Positive_regulation of Gene_expression of Olr1 1 0.00 2.12 0.33
110 INT298472 LPA Positive_regulation of Gene_expression of CXCL16 1 0.05 0.41 0.32
111 INT350214 Binding of GPER and HSPG2 1 0.00 0.12 0.32
112 INT215395 Csf2 Positive_regulation of Ppara 1 0.12 1.33 0.32
113 INT122049 Binding of HSD11B1 and Lcat 1 0.21 0.83 0.31
114 INT148556 PPARG Regulation of Gene_expression of PPARA 1 0.30 1.2 0.31
115 INT332972 Fas Positive_regulation of Ppara 1 0.17 0.52 0.31
116 INT187603 Binding of Ptgis and Ppara 1 0.00 0.26 0.31
117 INT207434 LPA Regulation of Gene_expression of PLA2G7 1 0.11 0.73 0.31
118 INT333453 Binding of PPARA and RXRA 1 0.02 0 0.31
119 INT209931 IL1B Positive_regulation of PPARA 1 0.32 0.62 0.31
120 INT307215 Negative_regulation of Prkca Negative_regulation of Ppara 1 0.09 0.21 0.3
121 INT35963 Binding of ALB and MPG 1 0.40 0 0.3
122 INT209933 PPARA Regulation of Positive_regulation of IL1B 1 0.21 0.58 0.29
123 INT297335 Binding of Apoc3 and Hdl1 1 0.00 0.92 0.29
124 INT299956 Binding of PPARA and EPC1 1 0.09 0.34 0.29
125 INT126006 Binding of ALB and IL8 1 0.41 0.28 0.28
126 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28
127 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
128 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
129 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28
130 INT159201 Binding of Ppard and Ppara 1 0.01 0.68 0.28
131 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28
132 INT101510 PPARA Regulation of IL6 1 0.31 0.53 0.27
133 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
134 INT101508 PPARA Regulation of IL8 1 0.31 0.53 0.27
135 INT101509 PPARA Regulation of Gene_expression of IL8 1 0.31 0.53 0.27
136 INT101511 PPARA Regulation of Gene_expression of IL6 1 0.31 0.53 0.27
137 INT335130 PPARA Positive_regulation of Cyp8b1 1 0.37 0 0.27
138 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26
139 INT203733 Thbs1 Positive_regulation of Negative_regulation of Ppara 1 0.36 1.55 0.26
140 INT335049 PPARA Negative_regulation of Gene_expression of CYP7B1 1 0.27 0 0.26
141 INT167582 ENPP2 Regulation of Gene_expression of LPA 1 0.05 0.61 0.26
142 INT207441 Binding of LPA and PLA2G7 1 0.10 0.56 0.26
143 INT239335 Eef1a2 Positive_regulation of Ppara 1 0.27 0.57 0.26
144 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26
145 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25
146 INT242215 Binding of ANG and OLR1 1 0.02 1.63 0.25
147 INT207438 Binding of OLR1 and ERAL1 1 0.08 0.5 0.25
148 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
149 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
150 INT78296 Negative_regulation of Binding of Ptpra and Ldlr 1 0.22 0.25 0.24
151 INT186191 Binding of SCARB1 and TBP 1 0.03 2.57 0.24
152 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
153 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
154 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
155 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
156 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
157 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
158 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
159 INT78291 Binding of Ptpra and Ldlr 1 0.20 0.25 0.24
160 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23
161 INT298785 PPARA Positive_regulation of ACOX1 3 0.29 1.58 0.23
162 INT354926 IL6 Regulation of Gene_expression of ALB 1 0.14 1.3 0.23
163 INT238383 Tlr4 Positive_regulation of Ppara 1 0.17 0.41 0.23
164 INT305798 Binding of APOA1 and OxP-11D 1 0.02 0.45 0.23
165 INT215396 Il4 Positive_regulation of Gene_expression of Ppara 1 0.03 0.23 0.23
166 INT354924 IL6 Positive_regulation of Gene_expression of ALB 1 0.26 1.3 0.23
167 INT308084 Binding of HSPG2 and OXT 1 0.04 0.25 0.23
168 INT173294 LPA Positive_regulation of EGF 1 0.01 0.07 0.23
169 INT62090 CXCR1 Positive_regulation of HSPG2 1 0.54 0.18 0.23
170 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
171 INT229702 Binding of Ppara and Ros1 1 0.01 1.05 0.23
172 INT283857 APOA5 Positive_regulation of Positive_regulation of MAPK1 1 0.00 0.6 0.22
173 INT233929 PPARA Negative_regulation of ras 1 0.02 2.39 0.22
174 INT141623 OLR1 Positive_regulation of Gene_expression of TF 1 0.01 1.39 0.21
175 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
176 INT283860 APOA5 Negative_regulation of MAPK1 1 0.00 0.59 0.21
177 INT263339 Ptger2 Regulation of Ppara 1 0.09 0.44 0.21
178 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2
179 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
180 INT109409 PPARA Positive_regulation of Gene_expression of SAT1 1 0.54 0.75 0.2
181 INT209850 IL4 Positive_regulation of Gene_expression of PPARA 1 0.18 0.23 0.19
182 INT298787 Binding of PPARA and TUSC5 1 0.32 1.38 0.19
183 INT298784 PPARA Positive_regulation of CPT1B 1 0.28 1.61 0.19
184 INT335053 PPARA Positive_regulation of Gene_expression of LPL 1 0.21 0.34 0.19
185 INT220513 Ugt1a6b Positive_regulation of Ppara 1 0.01 0.98 0.18
186 INT57612 Binding of ALB and HGF 1 0.20 0.52 0.18
187 INT126007 Negative_regulation of Binding of ALB and IL8 1 0.37 0.18 0.18
188 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18
189 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
190 INT242993 Positive_regulation of Ppara Positive_regulation of Gene_expression of Spp1 1 0.24 0.66 0.18
191 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
192 INT47344 CPZ Negative_regulation of LCAT 1 0.29 0 0.18
193 INT312519 DAK Positive_regulation of PPARA 1 0.00 1.46 0.18
194 INT220524 Ppara Negative_regulation of Positive_regulation of Gdf15 1 0.01 0.56 0.17
195 INT161148 ALB Regulation of Gene_expression of COMMD3 1 0.08 0 0.17
196 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
197 INT220516 Ppara Negative_regulation of Positive_regulation of Atf3 1 0.10 0.56 0.17
198 INT302295 PPARA Regulation of OAS2 1 0.01 0.72 0.17
199 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
200 INT335131 PPARA Negative_regulation of Gene_expression of Fgg 1 0.01 0.59 0.17

Single Events

The table below shows the top 100 pain related interactions that have been reported for lipoprotein metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in lipoprotein metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
2 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
3 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
4 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
5 INT546 Binding of ALB 311 0.48 85.98 60.14
6 INT122041 Binding of Ppara 308 0.48 189.17 51.48
7 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75
8 INT103094 Binding of PPARA 308 0.47 177.26 34.75
9 INT9650 Gene_expression of LPA 141 0.75 104.57 29
10 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
11 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
12 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
13 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7
14 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6
15 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
16 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35
17 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65
18 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98
19 INT103096 Regulation of PPARA 113 0.60 62.47 14.57
20 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53
21 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89
22 INT18773 Localization of ALB 117 0.80 69.18 13.8
23 INT122037 Regulation of Ppara 93 0.62 56.28 12.89
24 INT194462 Localization of Ppara 94 0.78 68.33 12.09
25 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03
26 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
27 INT173159 Localization of PPARA 96 0.74 64.55 10.26
28 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76
29 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
30 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06
31 INT860 Regulation of ALB 48 0.60 25.11 8.95
32 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87
33 INT39406 Positive_regulation of OLR1 45 0.70 37.8 7.72
34 INT153814 Localization of LPA 19 0.65 18.25 7.68
35 INT181817 Negative_regulation of Gene_expression of Ppara 58 0.58 43.24 7.67
36 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21
37 INT197493 Localization of Apoe 61 0.79 27.48 7.06
38 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05
39 INT75382 Negative_regulation of HSPG2 20 0.57 15.18 7.03
40 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
41 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89
42 INT3757 Positive_regulation of Gene_expression of ALB 45 0.69 23.73 6.85
43 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84
44 INT19146 Negative_regulation of Apoa2 19 0.36 5.34 6.73
45 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
46 INT170922 Binding of Ppara 59 0.45 28.45 6.7
47 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6
48 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
49 INT181194 Regulation of Gene_expression of PPARA 31 0.44 21.27 5.96
50 INT63042 Binding of Apoe 59 0.48 31.23 5.88
51 INT87470 Gene_expression of SDC1 27 0.78 24.86 5.81
52 INT86025 Positive_regulation of Positive_regulation of PPARA 34 0.52 22.89 5.74
53 INT86023 Transcription of PPARA 60 0.66 25.8 5.7
54 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56
55 INT122038 Transcription of Ppara 35 0.71 20.5 5.12
56 INT170927 Negative_regulation of Ppara 27 0.54 13.58 5.12
57 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04
58 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04
59 INT17312 Binding of HSPG2 30 0.41 33.01 4.88
60 INT180379 Gene_expression of Olr1 31 0.36 36.46 4.84
61 INT136754 Gene_expression of SCARB1 64 0.77 43.28 4.82
62 INT11030 Binding of LPA 70 0.48 40.35 4.81
63 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
64 INT22557 Gene_expression of BMP1 3 0.59 20.18 4.73
65 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
66 INT197171 Negative_regulation of Binding of Ppara 15 0.43 11.51 4.41
67 INT107771 Localization of HSPG2 10 0.78 8.47 4.3
68 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08
69 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
70 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
71 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
72 INT114957 Positive_regulation of Transcription of PPARA 18 0.62 10.36 3.65
73 INT47678 Positive_regulation of Positive_regulation of HSPG2 7 0.49 3.94 3.56
74 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
75 INT57728 Regulation of LDLR 25 0.41 13.18 3.46
76 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
77 INT207449 Negative_regulation of OLR1 23 0.42 17.17 3.37
78 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32
79 INT5166 Binding of Ldlr 14 0.48 11.95 3.32
80 INT43985 Regulation of LPA 29 0.62 20.79 3.29
81 INT72141 Binding of Apoe 11 0.37 10.91 3.27
82 INT307634 Binding of BMP1 1 0.36 3.12 3.26
83 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
84 INT97710 Localization of Apoe 1 0.79 7.18 3.2
85 INT147522 Positive_regulation of Gene_expression of Ppara 28 0.47 15.82 3.18
86 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13
87 INT187618 Localization of Ppara 13 0.70 6.91 3.09
88 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05
89 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04
90 INT10830 Regulation of Apoa1 11 0.44 15.1 3.04
91 INT82913 Regulation of Ppara 15 0.61 10.66 3.03
92 INT83190 Gene_expression of Olr1 26 0.59 12.47 2.91
93 INT94437 Positive_regulation of Gene_expression of OLR1 17 0.70 16.04 2.8
94 INT10556 Regulation of Apoa2 5 0.44 0.51 2.8
95 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73
96 INT222961 Negative_regulation of Binding of PPARA 22 0.41 10.76 2.72
97 INT49759 Negative_regulation of CETP 43 0.58 52 2.68
98 INT100144 Negative_regulation of Positive_regulation of PPARA 17 0.49 12.71 2.68
99 INT50080 Binding of APOE 38 0.45 29.61 2.67
100 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64
101 INT112962 Regulation of Positive_regulation of Ppara 17 0.45 10.63 2.58
102 INT147517 Negative_regulation of Gene_expression of Ppara 12 0.37 3.46 2.55
103 INT101363 Regulation of OLR1 16 0.39 9.27 2.54
104 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
105 INT39407 Binding of OLR1 18 0.48 14.79 2.51
106 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
107 INT83193 Binding of Olr1 6 0.42 10 2.43
108 INT31134 Regulation of Binding of ALB 13 0.62 2.51 2.37
109 INT215379 Positive_regulation of Binding of Ppara 15 0.66 8.04 2.36
110 INT75756 Phosphorylation of LPA 5 0.68 0.67 2.35
111 INT2452 Localization of Apoa2 9 0.55 0 2.3
112 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
113 INT207852 Positive_regulation of Olr1 9 0.12 9.76 2.26
114 INT19537 Negative_regulation of Binding of ALB 6 0.43 3.32 2.26
115 INT142626 Negative_regulation of Localization of ALB 9 0.55 6.63 2.24
116 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
117 INT215378 Protein_catabolism of Ppara 12 0.86 5.12 2.14
118 INT58108 Positive_regulation of Positive_regulation of ALB 4 0.70 1.02 2.11
119 INT36616 Positive_regulation of Binding of ALB 8 0.67 3 2.07
120 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
121 INT45176 Negative_regulation of LPL 34 0.59 22.22 2.01
122 INT49313 Positive_regulation of Gene_expression of Apoa1 3 0.68 9.55 2.01
123 INT45838 Positive_regulation of LPL 15 0.69 11.33 2
124 INT282596 Localization of BMP1 2 0.61 4.04 1.97
125 INT190883 Gene_expression of Apoc3 16 0.38 14.18 1.93
126 INT120407 Positive_regulation of Localization of HSPG2 2 0.49 2.11 1.92
127 INT173180 Positive_regulation of Binding of PPARA 14 0.49 3.66 1.88
128 INT211984 Regulation of Binding of Ppara 11 0.45 9.55 1.87
129 INT168269 Negative_regulation of Positive_regulation of Ppara 3 0.38 0.57 1.87
130 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
131 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86
132 INT114708 Regulation of Olr1 5 0.40 1.55 1.86
133 INT125508 Negative_regulation of Olr1 6 0.39 1.83 1.84
134 INT21813 Gene_expression of Apoa2 10 0.61 3.68 1.81
135 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
136 INT136752 Positive_regulation of Gene_expression of SCARB1 5 0.69 10.63 1.76
137 INT173177 Positive_regulation of Localization of PPARA 21 0.49 12.61 1.74
138 INT9648 Positive_regulation of Gene_expression of LPA 15 0.59 11.31 1.72
139 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67
140 INT248253 Positive_regulation of Gene_expression of HSPG2 3 0.44 4.61 1.65
141 INT156484 Binding of Apoa1 4 0.47 6.78 1.63
142 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
143 INT9466 Binding of APOB 27 0.41 19.36 1.56
144 INT173198 Regulation of Binding of PPARA 17 0.43 9.58 1.47
145 INT125800 Gene_expression of P4HB 5 0.47 5.4 1.47
146 INT112963 Regulation of Positive_regulation of PPARA 8 0.44 5.29 1.43
147 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
148 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
149 INT173162 Phosphorylation of PPARA 22 0.80 11.09 1.38
150 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36
151 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
152 INT10829 Regulation of Ldlr 12 0.34 8.12 1.35
153 INT122040 Positive_regulation of Transcription of Ppara 9 0.50 3.97 1.33
154 INT116721 Positive_regulation of Olr1 11 0.49 5.43 1.31
155 INT214574 Positive_regulation of SDC1 4 0.32 3.24 1.28
156 INT20238 Regulation of APOB 9 0.61 11.52 1.26
157 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
158 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
159 INT207849 Negative_regulation of Olr1 8 0.09 15.71 1.22
160 INT257952 Positive_regulation of CUBN 1 0.07 0.61 1.22
161 INT197167 Positive_regulation of Localization of Ppara 18 0.67 9.51 1.21
162 INT183635 Negative_regulation of Positive_regulation of Ppara 11 0.42 10 1.2
163 INT212988 Positive_regulation of Gene_expression of Olr1 8 0.24 6.64 1.2
164 INT227548 Negative_regulation of Localization of Ppara 7 0.38 4.1 1.17
165 INT23199 Binding of LDLR 22 0.47 17.08 1.16
166 INT82703 Transcription of LDLR 6 0.64 0.4 1.13
167 INT168675 Binding of P4HB 3 0.20 1.98 1.11
168 INT38265 Gene_expression of LPL 22 0.78 10.59 1.09
169 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
170 INT9075 Regulation of Positive_regulation of ALB 3 0.45 0.76 1.06
171 INT79928 Positive_regulation of Localization of ALB 10 0.60 8.96 1.05
172 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
173 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
174 INT206140 Negative_regulation of Gene_expression of LPA 5 0.43 3.71 1.03
175 INT120395 Regulation of HSPG2 4 0.26 5.96 1.03
176 INT188513 Negative_regulation of Binding of Ppara 2 0.35 2.02 1.01
177 INT44874 Regulation of LCAT 1 0.62 0.15 1
178 INT52113 Gene_expression of CETP 25 0.69 25.71 0.99
179 INT82707 Positive_regulation of Transcription of LDLR 1 0.62 0.34 0.98
180 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97
181 INT147518 Regulation of Gene_expression of Ppara 7 0.42 4.59 0.97
182 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
183 INT82702 Positive_regulation of Positive_regulation of LDLR 4 0.45 1.08 0.95
184 INT227552 Regulation of Phosphorylation of Ppara 7 0.44 3.13 0.92
185 INT57596 Regulation of Gene_expression of ALB 9 0.44 5.44 0.91
186 INT236104 Positive_regulation of Negative_regulation of Ppara 6 0.59 6.91 0.91
187 INT150117 Localization of P4HB 3 0.78 3.81 0.91
188 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9
189 INT180451 Positive_regulation of Apoa2 15 0.67 12.65 0.89
190 INT72672 Positive_regulation of Gene_expression of APOA1 4 0.67 3.81 0.89
191 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88
192 INT190361 Protein_catabolism of PPARA 12 0.97 3.01 0.87
193 INT190363 Positive_regulation of Negative_regulation of PPARA 10 0.44 4.8 0.87
194 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85
195 INT161754 Transcription of Ppara 10 0.52 4.06 0.84
196 INT10828 Regulation of Apob 7 0.39 7.55 0.83
197 INT190089 Binding of Abca1 5 0.36 2.21 0.83
198 INT90363 Regulation of SDC1 3 0.45 3.68 0.83
199 INT90364 Positive_regulation of Gene_expression of SDC1 3 0.70 2.59 0.83
200 INT191528 Positive_regulation of Localization of LPA 1 0.05 3.59 0.83
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