GO:0042162

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Name telomeric DNA binding
Categary Function
Go Slim No
Go Link GO:0042162
Unique Molecular Interactions 56
Total Molecular Interactions 81
Total Single Events 508
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for telomeric DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for telomeric DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT31950 PIF1 Positive_regulation of Localization of Prl 1 0.06 0 0.87
2 INT136199 Hnrpd Regulation of Gene_expression of Penk 1 0.46 0 0.74
3 INT31951 Negative_regulation of PIF1 Positive_regulation of Prl 1 0.07 0 0.68
4 INT249717 Binding of NCL and MCF2L 1 0.23 0 0.54
5 INT189688 PRKCA Regulation of Transcription of TERT 1 0.13 0.2 0.5
6 INT31952 Localization of PIF1 Regulation of Localization of Prl 1 0.04 0 0.46
7 INT31953 PIF1 Regulation of Localization of Prl 1 0.06 0 0.46
8 INT189687 INSRR Negative_regulation of Transcription of TERT 1 0.00 0.24 0.35
9 INT327328 Binding of Hnrnpd and Elavl1 1 0.06 0.74 0.3
10 INT327340 Binding of TNF and Hnrnpd 1 0.03 1.02 0.25
11 INT327300 Binding of Hnrnpd and Myc 1 0.12 1.02 0.25
12 INT202808 Binding of Pin1 and Hnrpd 1 0.08 0.84 0.22
13 INT327325 Binding of Hnrnpd and Ccnd1 1 0.03 0.38 0.16
14 INT285948 IL17A Regulation of Gene_expression of TERT 1 0.00 0.58 0.11
15 INT189702 CHKB Regulation of Gene_expression of TERT 1 0.06 0.55 0.1
16 INT10745 Fn1 Regulation of PIF1 1 0.02 0.38 0.1
17 INT188007 NLRP3 Regulation of Binding of TP53BP1 1 0.28 0.62 0.08
18 INT309511 Binding of Xrcc6 and Xrcc5 1 0.18 1.18 0.08
19 INT202807 Pin1 Regulation of Binding of Hnrpd 1 0.06 0.14 0.08
20 INT174561 Binding of Cd28 and Ncl 1 0.00 0.62 0.07
21 INT189677 CHKB Regulation of Transcription of TERT 1 0.10 1 0.05
22 INT189679 INSRR Regulation of Transcription of TERT 1 0.00 1 0.05
23 INT310727 Binding of DKC1 and TERT 1 0.23 0.91 0.05
24 INT188006 NLRP3 Regulation of Gene_expression of TP53BP1 1 0.28 0.36 0.04
25 INT188005 NLRP3 Regulation of TP53BP1 1 0.34 0.3 0.04
26 INT285944 IL6 Positive_regulation of Gene_expression of TERT 1 0.01 0.36 0.04
27 INT313307 TERT Positive_regulation of NFE2L2 1 0.01 0 0
28 INT189703 MZF1 Regulation of TERT 1 0.03 0.46 0
29 INT285941 IL6 Regulation of Gene_expression of TERT 1 0.01 0.12 0
30 INT189705 INSRR Negative_regulation of Gene_expression of TERT 1 0.00 0.46 0
31 INT189697 INSRR Regulation of Gene_expression of TERT 1 0.00 0.46 0
32 INT270759 Binding of HSD11B1 and TERT 1 0.07 1.67 0
33 INT225642 Binding of XRCC5 and Acsl1 1 0.01 0 0
34 INT269846 Binding of F3 and Ncl 1 0.21 3.19 0
35 INT189690 USF1 Regulation of TERT 1 0.05 0.46 0
36 INT189669 INSRR Regulation of TERT 1 0.00 0 0
37 INT189685 USF1 Positive_regulation of Transcription of TERT 1 0.05 0.27 0
38 INT309519 Xrcc5 Regulation of Gene_expression of Htt 1 0.18 0.08 0
39 INT189698 CHKB Regulation of TERT 1 0.06 0 0
40 INT253014 Binding of XRCC5 and Zic2 1 0.00 0.14 0
41 INT189673 BCL2 Positive_regulation of Transcription of TERT 1 0.09 0 0
42 INT189676 CCND3 Regulation of Transcription of TERT 1 0.02 0.06 0
43 INT225614 Binding of XRCC5 and Parp1 1 0.09 0 0
44 INT347292 AREG Negative_regulation of Gene_expression of TERT 1 0.02 0.78 0
45 INT189672 Positive_regulation of INSRR Regulation of Transcription of TERT 1 0.00 0.23 0
46 INT189682 CHKB Negative_regulation of Gene_expression of TERT 1 0.10 0.46 0
47 INT252904 Binding of PRKDC and XRCC5 1 0.00 0.14 0
48 INT204488 Binding of Fmr1 and Ncl 1 0.12 0.61 0
49 INT189684 RNF2 Regulation of TERT 1 0.02 0.46 0
50 INT313302 Regulation of TERT Positive_regulation of SQSTM1 1 0.01 0 0
51 INT285937 IL6 Regulation of TERT 1 0.01 0.12 0
52 INT313291 TERT Positive_regulation of SQSTM1 1 0.02 0 0
53 INT204483 Binding of Ncl and Hnrnpa2b1 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for telomeric DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in telomeric DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42
2 INT121494 Transcription of TERT 64 0.69 10.03 5.55
3 INT10744 Positive_regulation of PIF1 11 0.66 3.95 3.69
4 INT4313 Localization of PIF1 8 0.39 0.38 2.83
5 INT133194 Negative_regulation of TERT 23 0.48 4.01 2.45
6 INT189770 Positive_regulation of Transcription of TERT 1 0.28 1.36 2.14
7 INT136198 Gene_expression of Hnrpd 1 0.61 0 2.04
8 INT189766 Regulation of Transcription of TERT 1 0.25 3.48 1.99
9 INT136197 Binding of Hnrpd 3 0.38 0.56 1.76
10 INT147403 Regulation of Gene_expression of TERT 11 0.27 3.45 1.54
11 INT129712 Positive_regulation of Gene_expression of TERT 12 0.70 7.3 1.44
12 INT149649 Binding of Hnrnpd 2 0.14 3.59 1.44
13 INT133193 Positive_regulation of TERT 16 0.50 6.43 1.38
14 INT31949 Negative_regulation of PIF1 5 0.05 4 1.38
15 INT147607 Binding of TERT 16 0.48 12.36 1.31
16 INT189736 Regulation of TERT 22 0.40 3.58 1.29
17 INT133195 Negative_regulation of Transcription of TERT 4 0.42 2.9 1.08
18 INT4315 Negative_regulation of Localization of PIF1 2 0.16 0.08 1.01
19 INT189734 Negative_regulation of Gene_expression of TERT 8 0.24 1.84 0.85
20 INT72707 Binding of PIF1 2 0.35 0.42 0.6
21 INT72706 Positive_regulation of Binding of PIF1 1 0.47 0.42 0.56
22 INT182441 Positive_regulation of NCL 2 0.41 0 0.52
23 INT189756 Positive_regulation of Phosphorylation of TERT 1 0.28 0.2 0.5
24 INT189728 Phosphorylation of TERT 1 0.34 0.2 0.5
25 INT249719 Gene_expression of NCL 1 0.59 0.2 0.49
26 INT249720 Regulation of NCL 1 0.62 0 0.47
27 INT188016 Gene_expression of TP53BP1 6 0.64 5.54 0.35
28 INT4314 Positive_regulation of Localization of PIF1 2 0.13 0.08 0.34
29 INT189760 Negative_regulation of Negative_regulation of TERT 1 0.24 0.11 0.34
30 INT189739 Negative_regulation of Regulation of TERT 1 0.18 0.17 0.32
31 INT327237 Negative_regulation of Binding of Hnrnpd 1 0.13 0.94 0.29
32 INT188021 Positive_regulation of TP53BP1 3 0.48 1.33 0.25
33 INT54563 Negative_regulation of Positive_regulation of PIF1 1 0.42 0.86 0.23
34 INT149647 Positive_regulation of Gene_expression of Hnrnpd 3 0.20 1.14 0.22
35 INT149648 Gene_expression of Hnrnpd 2 0.23 1.14 0.22
36 INT188019 Negative_regulation of TP53BP1 1 0.48 1.42 0.18
37 INT202771 Regulation of Hnrpd 1 0.05 0.69 0.15
38 INT189761 Positive_regulation of Regulation of TERT 1 0.19 0.14 0.14
39 INT204447 Binding of Ncl 3 0.18 1.99 0.11
40 INT180135 Gene_expression of PIF1 1 0.04 0.22 0.11
41 INT202769 Transcription of Hnrpd 1 0.12 0.15 0.11
42 INT202768 Negative_regulation of Binding of Hnrpd 1 0.08 0.15 0.11
43 INT202772 Localization of Hnrpd 1 0.07 0.14 0.1
44 INT188013 Phosphorylation of TP53BP1 1 0.78 1.81 0.09
45 INT188017 Binding of TP53BP1 1 0.46 1.28 0.08
46 INT309460 Binding of Xrcc5 1 0.16 0.09 0.08
47 INT188010 Positive_regulation of Gene_expression of TP53BP1 1 0.48 0.43 0.07
48 INT61978 Regulation of PIF1 2 0.22 0.15 0.06
49 INT188020 Localization of TP53BP1 1 0.71 0.36 0.06
50 INT188008 Regulation of TP53BP1 4 0.37 1.1 0.04
51 INT327248 Regulation of Binding of Hnrnpd 1 0.13 0.05 0.04
52 INT327259 Regulation of Hnrnpd 1 0.13 0.05 0.04
53 INT274377 Localization of TERT 3 0.70 0.78 0
54 INT204459 Gene_expression of Ncl 2 0.35 2.08 0
55 INT223278 Positive_regulation of Binding of TERT 2 0.44 1.35 0
56 INT188014 Negative_regulation of Phosphorylation of TP53BP1 1 0.40 0.68 0
57 INT347316 Negative_regulation of Binding of TERT 1 0.18 0.26 0
58 INT188009 Regulation of Regulation of TP53BP1 1 0.37 0.07 0
59 INT189751 Regulation of Regulation of TERT 1 0.11 0.08 0
60 INT269841 Localization of Ncl 1 0.41 1.51 0
61 INT348467 Positive_regulation of XRCC5 1 0.25 0.43 0
62 INT182424 Localization of NCL 1 0.07 0 0
63 INT269840 Regulation of Ncl 1 0.14 1.59 0
64 INT260376 Protein_catabolism of TERT 1 0.02 0.36 0
65 INT180147 Negative_regulation of Gene_expression of PIF1 1 0.02 0 0
66 INT309467 Gene_expression of Xrcc5 1 0.26 0.1 0
67 INT309483 Positive_regulation of Xrcc5 1 0.20 0.1 0
68 INT188012 Regulation of Binding of TP53BP1 1 0.58 0.14 0
69 INT225463 Binding of XRCC5 1 0.36 0 0
70 INT188015 Negative_regulation of Localization of TP53BP1 1 0.35 0.16 0
71 INT188011 Negative_regulation of Gene_expression of TP53BP1 1 0.40 0.78 0
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