GO:0042164

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Name interleukin-12 alpha subunit binding
Categary Function
Go Slim No
Go Link GO:0042164
Unique Molecular Interactions 27
Total Molecular Interactions 29
Total Single Events 588
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interleukin-12 alpha subunit binding. They are ordered first by their pain relevance and then by number of times they were reported for interleukin-12 alpha subunit binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT209029 Il12b Positive_regulation of Elf1 1 0.24 0.37 0.72
2 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
3 INT209030 Il12b Positive_regulation of Cxcl1 1 0.16 0.37 0.72
4 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72
5 INT209032 Il12b Positive_regulation of Csf2 1 0.08 0.37 0.72
6 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57
7 INT237778 Il12b Positive_regulation of Gene_expression of Eae1 1 0.01 1.51 0.39
8 INT217028 Adp Negative_regulation of Il12b 1 0.00 0 0.37
9 INT237380 Binding of Cdkn2d and Il12b 1 0.01 0.45 0.26
10 INT355882 TNF Positive_regulation of Gene_expression of Il12b 1 0.03 0.21 0.18
11 INT233386 Binding of Il12a and Il12b 1 0.01 0.48 0.15
12 INT237774 Il12b Positive_regulation of Eae1 1 0.01 0.58 0.13
13 INT186375 TNF Negative_regulation of Gene_expression of Il12b 1 0.03 0.78 0.06
14 INT233387 Binding of SPINK1 and Il12b 1 0.04 0.33 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for interleukin-12 alpha subunit binding. They are ordered first by their pain relevance and then by number of times they were reported in interleukin-12 alpha subunit binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68
2 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89
3 INT144231 Gene_expression of Il12b 18 0.75 12.93 3.65
4 INT133169 Positive_regulation of Il12b 25 0.49 13 3.64
5 INT133174 Positive_regulation of Gene_expression of Il12b 29 0.15 13.04 2.92
6 INT92648 Positive_regulation of IL12B 7 0.20 4.55 2.19
7 INT74156 Positive_regulation of Il12b 3 0.49 1.54 2.04
8 INT92056 Transcription of Il12b 8 0.69 4.75 1.95
9 INT133170 Negative_regulation of Il12b 12 0.05 5.32 1.86
10 INT174230 Positive_regulation of Gene_expression of IL12B 6 0.49 3.2 1.56
11 INT97142 Localization of IL12B 5 0.73 1.73 1.46
12 INT236329 Regulation of IL12B 3 0.02 0.78 1.2
13 INT92055 Positive_regulation of Transcription of Il12b 4 0.49 2.77 1.16
14 INT233357 Localization of Il12b 7 0.16 3.4 1.12
15 INT144232 Negative_regulation of Gene_expression of Il12b 4 0.41 2.26 1.01
16 INT233349 Regulation of Il12b 5 0.05 3.71 0.98
17 INT133173 Regulation of Negative_regulation of Il12b 2 0.04 0.52 0.97
18 INT92649 Negative_regulation of Gene_expression of IL12B 3 0.03 2.23 0.86
19 INT186283 Negative_regulation of Gene_expression of Il12b 2 0.13 7.92 0.74
20 INT74155 Transcription of Il12b 3 0.60 1.45 0.66
21 INT156544 Regulation of Il12b 2 0.44 1.29 0.66
22 INT186277 Binding of Il12b 4 0.20 2.15 0.55
23 INT330393 Positive_regulation of Gene_expression of Il12b 2 0.49 1.24 0.48
24 INT233355 Positive_regulation of Localization of Il12b 2 0.11 0.99 0.43
25 INT185318 Negative_regulation of Transcription of Il12b 2 0.06 1.03 0.43
26 INT233356 Negative_regulation of Positive_regulation of Il12b 3 0.13 0.85 0.38
27 INT233350 Regulation of Gene_expression of Il12b 1 0.06 3.03 0.37
28 INT92652 Negative_regulation of Positive_regulation of IL12B 1 0.03 0.99 0.36
29 INT348183 Binding of IL12B 1 0.46 0.97 0.33
30 INT329823 Negative_regulation of Il12b 1 0.42 0.57 0.27
31 INT294675 Localization of Il12b 2 0.78 1.15 0.19
32 INT119167 Positive_regulation of Transcription of Il12b 1 0.09 0.77 0.17
33 INT237761 Phosphorylation of Il12b 1 0.09 0.49 0.11
34 INT233354 Positive_regulation of Positive_regulation of Il12b 1 0.06 2.91 0.07
35 INT186310 Positive_regulation of Binding of Il12b 1 0.15 1.07 0.07
36 INT97135 Positive_regulation of Localization of IL12B 2 0.49 0.92 0.05
37 INT305355 Transcription of IL12B 1 0.52 0.46 0.03
38 INT97143 Regulation of Localization of IL12B 1 0.08 0 0
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