GO:0042220

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Name response to cocaine
Categary Process
Go Slim No
Go Link GO:0042220
Unique Molecular Interactions 1154
Total Molecular Interactions 1705
Total Single Events 18949
Pain Genes Associated 48

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to cocaine. They are ordered first by their pain relevance and then by number of times they were reported for response to cocaine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
2 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
3 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
4 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
5 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
6 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
7 INT143270 Binding of Cnr1 and Gprasp1 4 0.54 0.64 4.18
8 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
9 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97
10 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
11 INT69938 Cck Positive_regulation of Localization of Abat 2 0.29 0 3.78
12 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
13 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
14 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
15 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19
16 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
17 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
18 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
19 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
20 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89
21 INT69937 Cck Positive_regulation of Abat 2 0.31 0 2.88
22 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
23 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64
24 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
25 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
26 INT104219 SCD Positive_regulation of Cnr1 1 0.00 2.67 2.54
27 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 0.78 0.16 2.53
28 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
29 INT314141 Binding of Tacr3 and SFTPA1 1 0.00 3.02 2.48
30 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
31 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
32 INT143272 Binding of CNR1 and Gprasp1 1 0.01 0.17 2.42
33 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
34 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
35 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
36 INT198958 Cnr1 Positive_regulation of Kcnj9 1 0.00 0.15 2.24
37 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
38 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
39 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
40 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
41 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
42 INT245348 Binding of Abat and Vta1 1 0.03 0.53 2.01
43 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
44 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
45 INT34662 Abat Positive_regulation of Localization of Gnrh1 1 0.26 0 1.98
46 INT58678 Binding of Penk and Abat 2 0.40 1.39 1.97
47 INT13430 Abat Positive_regulation of Localization of Sst 2 0.33 0 1.94
48 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
49 INT264928 Binding of Cnr1 and Hrh1 1 0.01 1.61 1.92
50 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
51 INT40238 Penk Regulation of Oxt 1 0.04 0 1.83
52 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
53 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
54 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78
55 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76
56 INT253895 Binding of Htr1b and Htr1d 1 0.40 0.52 1.74
57 INT264922 Binding of Cnr1 and Mors1 1 0.14 0.1 1.71
58 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
59 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71
60 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
61 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
62 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 0.14 0 1.7
63 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66
64 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
65 INT90658 Abat Regulation of Localization of Cck 2 0.24 0 1.64
66 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
67 INT172206 Binding of Slc6a3 and ADHD1 2 0.03 2.76 1.61
68 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
69 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59
70 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
71 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
72 INT192081 Igkv11-125 Positive_regulation of Cnr1 1 0.10 0.23 1.51
73 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
74 INT64628 Binding of Oxt and Gal 2 0.29 0.29 1.49
75 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
76 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
77 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
78 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
79 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
80 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
81 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
82 INT30872 Abat Positive_regulation of Localization of Gast 1 0.26 0 1.43
83 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
84 INT150069 Cnr1 Regulation of Cnr2 2 0.50 0.83 1.42
85 INT10548 Nts Regulation of Localization of Abat 2 0.14 0 1.42
86 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
87 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
88 INT100908 Slc6a3 Regulation of Positive_regulation of Etf1 1 0.05 0 1.41
89 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
90 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
91 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
92 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
93 INT26812 SST Regulation of Localization of OXT 1 0.40 0.57 1.37
94 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36
95 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35
96 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
97 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
98 INT198957 Binding of Cnr1 and Mastl 1 0.00 0 1.31
99 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
100 INT124925 Negative_regulation of Slc6a1 Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
101 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3
102 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
103 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
104 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29
105 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
106 INT7284 Abat Regulation of Sst 1 0.18 0 1.28
107 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
108 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
109 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
110 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
111 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
112 INT119713 Negative_regulation of Slc6a3 Positive_regulation of Cpu3 1 0.39 0.71 1.26
113 INT86090 SCN5A Negative_regulation of Positive_regulation of Abat 1 0.00 0 1.25
114 INT126801 Regulation of Binding of Oprm1 and Penk 1 0.34 0.4 1.25
115 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
116 INT7887 Oprl1 Regulation of Localization of Oxt 2 0.16 0 1.23
117 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
118 INT184919 Binding of da and Slc6a3 1 0.12 0.33 1.23
119 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
120 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
121 INT76165 IGKV2-30 Positive_regulation of Phosphorylation of Oprm1 1 0.00 0.08 1.22
122 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
123 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2
124 INT90644 Slc6a3 Positive_regulation of Th 1 0.51 0 1.2
125 INT63384 Binding of Cnr1 and Insrr 1 0.03 0.24 1.2
126 INT81097 Akr1d1 Regulation of Localization of Abat 1 0.00 0 1.2
127 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
128 INT29714 Crh Regulation of Localization of LH 2 0.26 0 1.19
129 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
130 INT34661 Abat Positive_regulation of Localization of Pomc 1 0.04 0 1.18
131 INT30871 Abat Regulation of Localization of Sst 1 0.13 0 1.17
132 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
133 INT209132 Binding of Drd2 and Riok3 1 0.01 1.57 1.16
134 INT76256 Binding of Slc6a3 and Sigmar1 1 0.20 0 1.16
135 INT212815 WAS Positive_regulation of CNR1 1 0.01 0.62 1.16
136 INT212824 WAS Positive_regulation of Cnr1 1 0.21 0.62 1.16
137 INT336559 SLC6A3 Positive_regulation of GOPC 1 0.08 1 1.15
138 INT262336 Binding of Abat and Tmem132a 1 0.00 1.39 1.14
139 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
140 INT264930 Gnaz Positive_regulation of Negative_regulation of Cnr1 1 0.20 0 1.14
141 INT225104 CNR1 Positive_regulation of Gene_expression of RETNLB 1 0.01 1.41 1.14
142 INT321476 Binding of Slc6a3 and Slc6a2 1 0.01 0.41 1.14
143 INT321473 Binding of Slc6a3 and Ubqln1 1 0.00 0.41 1.13
144 INT30359 Pomc Regulation of Localization of Oxt 1 0.03 0 1.13
145 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
146 INT110671 Binding of Cnr1 and Alox5 1 0.07 0.2 1.13
147 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
148 INT86263 Binding of Tacr3 and Tac2 1 0.16 0.52 1.13
149 INT102570 Abat Regulation of Gene_expression of Penk 3 0.13 0 1.12
150 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
151 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12
152 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
153 INT29713 Crh Negative_regulation of Localization of Gnrhr 1 0.39 0 1.12
154 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12
155 INT73679 Nkx1-1 Positive_regulation of Tacr3 1 0.22 0.26 1.12
156 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
157 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
158 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
159 INT29874 OXTR Negative_regulation of POMC 1 0.22 0 1.1
160 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
161 INT74185 Cck Negative_regulation of Drd1a 1 0.30 0.1 1.1
162 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
163 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
164 INT53176 Spink4 Regulation of Localization of Abat 1 0.19 0 1.09
165 INT60584 Positive_regulation of Htr3a Positive_regulation of Localization of Cck 1 0.52 0.43 1.09
166 INT79323 Abat Regulation of Vmn2r1 1 0.00 0 1.08
167 INT53842 Abat Regulation of Gabrd 1 0.04 1 1.08
168 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07
169 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06
170 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
171 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
172 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
173 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
174 INT87855 Flvcr2 Positive_regulation of Localization of Abat 1 0.02 0 1.05
175 INT38936 Binding of Avp and Crh 7 0.40 0.82 1.04
176 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
177 INT153963 Gatsl2 Regulation of Abat 1 0.02 0.97 1.03
178 INT104089 Vta1 Negative_regulation of Abat 1 0.14 0 1.03
179 INT75247 Abat Regulation of Gene_expression of Tacr1 1 0.23 0.41 1.03
180 INT63103 AVP Regulation of OXT 1 0.28 0.68 1.02
181 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
182 INT338892 TNFSF14 Regulation of Abat 1 0.00 0.61 1.01
183 INT131173 Chrna7 Positive_regulation of Localization of Abat 1 0.10 0 1.01
184 INT338895 TNFSF14 Regulation of Regulation of Abat 1 0.00 0.62 1.01
185 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
186 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
187 INT21332 Binding of Drd2 and Gm5195 1 0.01 0.26 1
188 INT245349 Binding of Abat and Gpr156 1 0.02 0.26 1
189 INT70105 SCD Positive_regulation of Oprm1 1 0.01 0 1
190 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1
191 INT5612 Cck Positive_regulation of Localization of Crh 1 0.65 0.16 1
192 INT351443 Cnr1 Regulation of Positive_regulation of Vta1 1 0.12 0.93 0.99
193 INT175805 Crh Positive_regulation of Gene_expression of POMC 1 0.12 1.07 0.99
194 INT209151 OXT Positive_regulation of PNLIP 1 0.08 0.73 0.99
195 INT147506 Binding of Ncam1 and Gtf3a 1 0.03 0.88 0.99
196 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
197 INT147504 Binding of Ncam1 and Gdnf 1 0.31 0.87 0.98
198 INT34660 Abat Regulation of Localization of Gnrh1 1 0.17 0 0.98
199 INT31494 Pomc Regulation of Crh 2 0.12 0.13 0.97
200 INT57555 Binding of Oprm1 and Oprl1 2 0.06 0.05 0.97

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to cocaine. They are ordered first by their pain relevance and then by number of times they were reported in response to cocaine. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3439 Localization of Abat 1017 0.78 112.39 727.06
2 INT3579 Localization of Oxt 555 0.81 43.35 292.44
3 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43
4 INT1562 Localization of Crh 499 0.81 126.74 236.68
5 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34
6 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
7 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98
8 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36
9 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
10 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
11 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
12 INT2910 Regulation of Abat 169 0.62 36.95 153.53
13 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48
14 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
15 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
16 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34
17 INT1898 Regulation of Crh 220 0.62 61.33 102.64
18 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
19 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
20 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49
21 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7
22 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7
23 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59
24 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43
25 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
26 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
27 INT451 Regulation of Oxt 142 0.62 22.07 69.42
28 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
29 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33
30 INT7468 Negative_regulation of Localization of Oxt 109 0.59 9.46 66.79
31 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47
32 INT2212 Binding of Abat 89 0.48 18.36 63.99
33 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84
34 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71
35 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
36 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57
37 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
38 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
39 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
40 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75
41 INT5858 Positive_regulation of Drd1a 66 0.69 4.51 51.73
42 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51
43 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
44 INT63383 Binding of Cnr1 77 0.48 22.28 44.61
45 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
46 INT12228 Positive_regulation of Gene_expression of Abat 44 0.65 17.51 40.55
47 INT16194 Binding of CNR1 82 0.48 20.75 39.59
48 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
49 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
50 INT81037 Negative_regulation of Slc6a3 70 0.59 15.31 37.01
51 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
52 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
53 INT12608 Regulation of CNR1 62 0.60 24.36 36.02
54 INT13501 Binding of Drd2 65 0.48 23.76 35.6
55 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52
56 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
57 INT50308 Binding of Cnr1 61 0.48 14.41 33.52
58 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
59 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
60 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
61 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
62 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
63 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
64 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
65 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
66 INT16879 Binding of Crh 72 0.48 21.65 28.43
67 INT21379 Transcription of Crh 65 0.72 15.64 27.92
68 INT2912 Positive_regulation of Positive_regulation of Abat 29 0.66 6.48 27.54
69 INT111359 Localization of Cnr1 55 0.81 11.25 27.41
70 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
71 INT75418 Negative_regulation of Cnr1 41 0.59 14.65 27.28
72 INT93360 Gene_expression of Slc6a3 63 0.78 19.54 26.55
73 INT63444 Regulation of Gene_expression of Abat 26 0.51 14.65 26.29
74 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
75 INT80791 Gene_expression of Slc6a3 113 0.78 11.89 25.76
76 INT74377 Regulation of Cnr1 38 0.59 16.93 24.77
77 INT12484 Binding of Drd2 45 0.48 15.17 24.72
78 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
79 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43
80 INT13838 Positive_regulation of Drd1a 48 0.70 9.83 23.42
81 INT9282 Gene_expression of HTR1B 48 0.75 12.15 22.94
82 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79
83 INT11077 Positive_regulation of Htr3a 63 0.67 15.61 22.7
84 INT7715 Regulation of Drd2 35 0.62 10.79 22.3
85 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
86 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34
87 INT61825 Negative_regulation of Slc6a3 47 0.59 6.52 21.27
88 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
89 INT49774 Binding of DRD2 48 0.48 17.42 20.73
90 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73
91 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31
92 INT10442 Negative_regulation of CNR1 47 0.59 20.88 20.2
93 INT9782 Binding of HTR1B 43 0.47 12.08 19.83
94 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29
95 INT79955 Localization of Cnr1 26 0.81 8.44 19.06
96 INT7680 Regulation of Drd1a 27 0.45 4.52 18.86
97 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
98 INT9230 Gene_expression of Htr3a 43 0.78 10.54 18.81
99 INT18672 Gene_expression of Ncam1 54 0.78 36.64 18.79
100 INT5533 Binding of Oxt 43 0.48 8.69 18.35
101 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
102 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66
103 INT51779 Gene_expression of Drd1a 46 0.66 11.18 17.51
104 INT9358 Positive_regulation of HTR1B 26 0.67 11 17.51
105 INT7020 Negative_regulation of Drd1a 25 0.57 1.84 17.1
106 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
107 INT65214 Binding of Slc6a3 54 0.48 4.77 16.79
108 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78
109 INT9069 Regulation of Htr3a 29 0.60 6.18 16.55
110 INT87932 Positive_regulation of Gene_expression of Cnr1 28 0.69 8.86 16.38
111 INT62629 Localization of CNR1 35 0.76 11.86 16.3
112 INT5859 Positive_regulation of Positive_regulation of Drd1a 20 0.55 2.05 15.61
113 INT129 Localization of OXTR 51 0.80 11.08 15.36
114 INT54356 Regulation of Slc6a3 48 0.58 5.86 15.24
115 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23
116 INT26729 Negative_regulation of Drd2 28 0.55 9.32 15.17
117 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
118 INT7469 Positive_regulation of Gene_expression of Oxt 18 0.59 4.7 14.36
119 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
120 INT74375 Positive_regulation of Gene_expression of Cnr1 24 0.70 14.25 13.66
121 INT68814 Positive_regulation of Transcription of Oprm1 16 0.60 2.72 13.57
122 INT24956 Gene_expression of Tacr3 22 0.74 7.21 13.37
123 INT49538 Binding of Gria1 22 0.47 2.66 13.35
124 INT5599 Regulation of Drd2 25 0.52 3.07 13.31
125 INT9231 Binding of Htr3a 27 0.47 7.29 13.04
126 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
127 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
128 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
129 INT12369 Negative_regulation of Htr3a 28 0.59 8.78 12.62
130 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
131 INT28458 Localization of Slc6a3 31 0.76 2.33 12.49
132 INT69763 Positive_regulation of Positive_regulation of Cnr1 12 0.50 9.05 12.46
133 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41
134 INT114674 Gene_expression of Mdm2 15 0.78 3.51 11.85
135 INT7682 Binding of Drd1a 22 0.48 1.8 11.83
136 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
137 INT6044 Regulation of Binding of Oprm1 16 0.61 3.01 11.11
138 INT59766 Positive_regulation of Negative_regulation of Oprm1 9 0.50 1.31 11.08
139 INT19575 Negative_regulation of Positive_regulation of Abat 14 0.43 2.07 11.05
140 INT39016 Transcription of Abat 19 0.53 3.92 10.82
141 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8
142 INT93967 Binding of Slc6a3 22 0.48 6.81 10.74
143 INT1708 Gene_expression of OXTR 56 0.78 6.92 10.69
144 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69
145 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
146 INT90639 Positive_regulation of Slc6a3 25 0.61 10.95 10.41
147 INT71592 Negative_regulation of Gene_expression of Oprm1 11 0.58 4.03 10.37
148 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
149 INT75955 Gene_expression of Drd3 19 0.77 4.39 10.07
150 INT8072 Localization of Gria1 17 0.75 2.62 10.04
151 INT106565 Negative_regulation of Gene_expression of Cnr1 19 0.59 6.98 9.93
152 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
153 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
154 INT57039 Positive_regulation of Gene_expression of Drd2 16 0.50 1.98 9.48
155 INT17764 Negative_regulation of Drd2 17 0.42 4.63 9.46
156 INT49483 Regulation of Positive_regulation of Oprm1 8 0.61 2.34 9.4
157 INT78038 Gene_expression of Oxtr 43 0.78 18.72 9.38
158 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
159 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
160 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
161 INT5939 Regulation of Gene_expression of Oxt 27 0.51 2.84 9.1
162 INT13296 Transcription of Drd2 17 0.66 2.7 9.07
163 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
164 INT6682 Regulation of Gene_expression of Drd2 13 0.51 2.17 8.82
165 INT76162 Positive_regulation of Phosphorylation of Oprm1 11 0.69 0.64 8.72
166 INT108643 Gene_expression of Dlg4 61 0.76 8.63 8.58
167 INT5359 Protein_catabolism of Abat 12 0.62 5.11 8.54
168 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
169 INT16735 Localization of Drd1a 11 0.61 0.35 8.42
170 INT18021 Positive_regulation of Binding of Oprm1 16 0.70 2.53 8.38
171 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
172 INT26815 Regulation of OXT 15 0.46 5.38 8.31
173 INT146343 Regulation of Slc6a3 17 0.60 7.33 8.27
174 INT28461 Positive_regulation of Localization of Slc6a3 8 0.41 0 8.24
175 INT5498 Positive_regulation of Positive_regulation of Crh 19 0.70 9.82 7.97
176 INT56580 Positive_regulation of Htr1b 16 0.67 2.95 7.97
177 INT13041 Binding of Htr1b 14 0.47 4.92 7.95
178 INT95317 Positive_regulation of Slc6a1 6 0.69 5.91 7.94
179 INT9966 Localization of Htr3a 14 0.80 2.28 7.92
180 INT114675 Positive_regulation of Gene_expression of Mdm2 1 0.70 1.98 7.9
181 INT10444 Positive_regulation of Gene_expression of CNR1 18 0.69 8.69 7.84
182 INT6957 Positive_regulation of OXTR 38 0.70 6.55 7.81
183 INT184845 Negative_regulation of Gene_expression of Slc6a3 13 0.59 3.25 7.79
184 INT28457 Positive_regulation of Slc6a3 26 0.50 3.64 7.76
185 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
186 INT18190 Regulation of DRD2 11 0.60 9.01 7.63
187 INT87976 Regulation of Gene_expression of Cnr1 9 0.58 6.87 7.51
188 INT75063 Regulation of Gene_expression of Drd2 10 0.62 2.82 7.38
189 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
190 INT105528 Negative_regulation of Slc6a1 7 0.57 2.79 7.32
191 INT86898 Negative_regulation of Gene_expression of Cnr1 13 0.55 3.33 7.25
192 INT6892 Regulation of Htr1b 9 0.60 1.32 7.24
193 INT73760 Transcription of Drd2 14 0.72 2.11 7.19
194 INT96969 Positive_regulation of Positive_regulation of CNR1 9 0.48 1.27 7.19
195 INT57023 Negative_regulation of Gene_expression of Gria1 20 0.58 6.92 7.17
196 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
197 INT25772 Regulation of HTR1B 15 0.60 3.8 7.17
198 INT15553 Negative_regulation of Htr1b 13 0.41 2.61 7.16
199 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
200 INT52132 Positive_regulation of Negative_regulation of Abat 9 0.50 0.53 7.03
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