GO:0042301

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Name phosphate ion binding
Categary Function
Go Slim No
Go Link GO:0042301
Unique Molecular Interactions 81
Total Molecular Interactions 104
Total Single Events 1091
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phosphate ion binding. They are ordered first by their pain relevance and then by number of times they were reported for phosphate ion binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
2 INT253863 Binding of LBP and PNP 1 0.13 1.5 1.5
3 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
4 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
5 INT256357 Phosphorylation of Rela Positive_regulation of Localization of Ik 1 0.00 0.05 0.96
6 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72
7 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
8 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
9 INT321285 Ins1 Negative_regulation of G6pc 1 0.07 0.52 0.59
10 INT28925 Cpe Regulation of Sh2b3 1 0.04 0.14 0.55
11 INT177782 PDCD2 Positive_regulation of MTHFD2 1 0.06 0.76 0.46
12 INT177787 BUB1B Positive_regulation of MTHFD2 1 0.15 0.76 0.46
13 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
14 INT256356 Binding of Nfkb1 and Rela 1 0.21 0 0.44
15 INT107704 IL1B Positive_regulation of Localization of RELA 1 0.02 0.13 0.41
16 INT321301 Fig4 Negative_regulation of G6pc 1 0.07 0.33 0.39
17 INT319729 Binding of Rela and Crebbp 1 0.02 0.88 0.37
18 INT129291 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of RELA 1 0.06 0.27 0.28
19 INT143950 Negative_regulation of NFKB1 Positive_regulation of Gene_expression of RELA 1 0.45 0.46 0.23
20 INT321286 Ins1 Negative_regulation of Transcription of G6pc 1 0.05 0.19 0.2
21 INT340447 Negative_regulation of IRF6 Positive_regulation of RELA 1 0.00 0.87 0.18
22 INT340448 IRF6 Positive_regulation of RELA 1 0.00 0.86 0.17
23 INT302930 Binding of Pnp and Chrm2 1 0.00 0.64 0.15
24 INT139821 ZNF833P Negative_regulation of Localization of RELA 1 0.00 0.11 0.15
25 INT153154 OPN1MW Regulation of PTPRF 1 0.03 0.51 0.14
26 INT280809 Binding of gr and Rela 1 0.00 0 0.13
27 INT319726 Crebbp Positive_regulation of Binding of Rela 1 0.02 0.37 0.12
28 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12
29 INT55163 Binding of RELA and WRAP53 1 0.01 0.05 0.1
30 INT321296 Rxfp2 Regulation of G6pc 1 0.07 0.07 0.09
31 INT243685 NDUFA2 Negative_regulation of Localization of RELA 1 0.07 0 0.09
32 INT301628 Irs2 Negative_regulation of Transcription of G6pc 1 0.04 0.65 0.08
33 INT163619 Ikbkb Regulation of Rela 1 0.18 0.23 0.08
34 INT163618 Chuk Regulation of Rela 1 0.16 0.23 0.08
35 INT301649 Irs1 Negative_regulation of Transcription of G6pc 1 0.05 0.65 0.08
36 INT195549 Lct Positive_regulation of Rela 1 0.01 0 0.07
37 INT208219 RELA Regulation of IRF6 1 0.00 0.07 0.07
38 INT340271 Fig4 Positive_regulation of Localization of RELA 1 0.01 0.68 0.04
39 INT240946 G6pc Positive_regulation of Regulation of Hgd 1 0.22 0.21 0.03
40 INT240943 G6pc Regulation of Regulation of Hgd 1 0.12 0.21 0.03
41 INT315269 Rela Regulation of Gene_expression of Nfe2l2 1 0.10 0.25 0.03
42 INT340276 Tnfsf11 Positive_regulation of Localization of RELA 1 0.02 0.58 0.03
43 INT315263 Eri1 Regulation of Rela 1 0.00 0.49 0
44 INT315052 Binding of IL8 and RELA 1 0.07 0.34 0
45 INT95305 RELA Positive_regulation of Nfkb1 1 0.00 0.08 0
46 INT322357 ma Regulation of Localization of Rela 1 0.05 0.36 0
47 INT320351 Pnp Regulation of Ighg2b 1 0.02 0.31 0
48 INT278014 Ptprf Regulation of Localization of Gh 1 0.61 0.31 0
49 INT315053 Negative_regulation of AKT1 Positive_regulation of Binding of RELA 1 0.10 0.12 0
50 INT332825 GCSH Negative_regulation of G6PC 1 0.48 0.25 0
51 INT86001 Binding of Pnp and Alms1 1 0.03 0 0
52 INT95308 Binding of RELA and Nfkb1 1 0.00 0.08 0
53 INT170586 CD40 Negative_regulation of Positive_regulation of RELA 1 0.12 0.24 0
54 INT320352 Pnp Positive_regulation of Ighg2b 1 0.03 0.08 0
55 INT95306 Negative_regulation of RELA Positive_regulation of Nfkb1 1 0.00 0.08 0
56 INT315266 Rela Positive_regulation of Negative_regulation of Nfe2l2 1 0.11 0.63 0
57 INT315261 Gopc Regulation of Gene_expression of Rela 1 0.03 0.6 0
58 INT302926 Binding of Pnp and Pbrm1 1 0.01 0.96 0
59 INT315270 Rela Positive_regulation of Negative_regulation of Keap1 1 0.10 0.63 0
60 INT315064 Binding of RELA and PAR4 1 0.08 0.45 0
61 INT215246 Binding of Rab27a and Rph3a 1 0.07 0.26 0
62 INT55165 Binding of REL and RELA 1 0.16 0.18 0
63 INT170590 RELA Negative_regulation of Gene_expression of ICAM1 1 0.42 0.49 0
64 INT228589 G6pc Regulation of Positive_regulation of Gck 1 0.03 0.05 0
65 INT215241 Binding of Rab3a and Rph3a 1 0.00 0.26 0
66 INT146469 Otc Regulation of Cp 1 0.10 0.23 0
67 INT232056 Binding of DDR1 and PNP 1 0.01 0.55 0
68 INT292159 Binding of NFKB2 and RELA 1 0.02 0.4 0
69 INT170588 RELA Regulation of Gene_expression of ICAM1 1 0.26 0 0
70 INT55166 Binding of PROC and RELA 1 0.01 0.09 0
71 INT189110 Binding of Pnp and Asprv1 1 0.00 0 0
72 INT95307 Negative_regulation of Binding of RELA and Nfkb1 1 0.00 0.08 0
73 INT95304 Positive_regulation of Binding of RELA and Nfkb1 1 0.00 0.08 0
74 INT302929 Binding of Pnp and Spna1 1 0.00 0.35 0
75 INT315062 Positive_regulation of Binding of RELA and PAR4 1 0.11 0.12 0
76 INT278017 Ptprf Regulation of Igf1 1 0.48 0.31 0
77 INT315051 AKT1 Regulation of Localization of RELA 1 0.09 0.07 0
78 INT197814 Binding of MEN1 and RELA 1 0.42 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phosphate ion binding. They are ordered first by their pain relevance and then by number of times they were reported in phosphate ion binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
2 INT93482 Localization of Rela 56 0.78 24.52 14.82
3 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
4 INT66213 Localization of RELA 63 0.78 14.71 8.77
5 INT253864 Negative_regulation of PNP 13 0.26 6.84 6.67
6 INT256345 Phosphorylation of Rela 21 0.75 9.51 6.56
7 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
8 INT28030 Binding of Otc 5 0.37 2.72 4.3
9 INT93483 Negative_regulation of Localization of Rela 11 0.57 5.1 4.19
10 INT158377 Positive_regulation of Positive_regulation of Rela 6 0.49 3.08 4.11
11 INT133550 Negative_regulation of Gene_expression of Rela 14 0.40 4.64 3.73
12 INT21869 Negative_regulation of Otc 16 0.58 8.43 3.67
13 INT195527 Binding of Rela 17 0.25 4.42 3.56
14 INT73557 Positive_regulation of RELA 57 0.46 8.7 3.43
15 INT45324 Positive_regulation of Otc 8 0.59 3.94 3.36
16 INT133557 Transcription of Rela 6 0.52 3.86 3.2
17 INT174232 Gene_expression of PNP 36 0.30 8.74 3.17
18 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09
19 INT153221 Positive_regulation of Rela 5 0.16 2.16 2.72
20 INT120515 Gene_expression of Otc 13 0.66 4.33 2.6
21 INT141195 Negative_regulation of Rela 14 0.29 8.61 2.44
22 INT162518 Positive_regulation of Localization of Rela 12 0.47 1.96 2.41
23 INT44979 Positive_regulation of Pnp 11 0.59 5.61 2.41
24 INT123530 Phosphorylation of RELA 9 0.80 3.46 1.99
25 INT144649 Negative_regulation of Positive_regulation of Rela 11 0.26 8.27 1.87
26 INT40322 Binding of Pnp 12 0.38 11.13 1.78
27 INT55169 Binding of RELA 40 0.36 4.91 1.74
28 INT108875 Positive_regulation of Localization of RELA 9 0.49 1.43 1.72
29 INT256341 Positive_regulation of Phosphorylation of Rela 5 0.46 2.12 1.62
30 INT133552 Negative_regulation of Transcription of Rela 2 0.23 2.43 1.34
31 INT110252 Positive_regulation of Gene_expression of RELA 29 0.49 6.36 1.31
32 INT153220 Negative_regulation of Positive_regulation of Rela 1 0.09 0.31 1.31
33 INT32796 Negative_regulation of G6pc 7 0.36 2.44 1.27
34 INT76925 Negative_regulation of G6pc 6 0.57 2.9 1.25
35 INT32797 Regulation of G6pc 2 0.28 1.63 1.23
36 INT202476 Positive_regulation of Gene_expression of Rela 10 0.34 3.65 1.22
37 INT321337 Transcription of G6pc 1 0.32 1.21 1.09
38 INT120514 Negative_regulation of Gene_expression of Otc 4 0.41 1.19 1.08
39 INT62237 Gene_expression of Ptprf 2 0.65 1.63 1.08
40 INT69442 Regulation of Otc 3 0.24 0.98 1.04
41 INT1267 Regulation of G6PC 3 0.44 1.39 0.98
42 INT158375 Positive_regulation of Transcription of Rela 2 0.45 0.8 0.94
43 INT321336 Negative_regulation of Transcription of G6pc 1 0.20 1.04 0.91
44 INT248678 Gene_expression of Rela 4 0.16 2.35 0.9
45 INT28924 Regulation of Sh2b3 1 0.43 0.32 0.8
46 INT28922 Binding of Sh2b3 1 0.34 0.31 0.79
47 INT32798 Positive_regulation of G6pc 5 0.49 1.25 0.78
48 INT256349 Regulation of Phosphorylation of Rela 3 0.31 0.26 0.77
49 INT50440 Negative_regulation of Pnp 5 0.36 2.14 0.66
50 INT108874 Regulation of Localization of RELA 5 0.44 1.09 0.61
51 INT194899 Positive_regulation of Negative_regulation of Rela 1 0.26 2.07 0.61
52 INT178715 Localization of Rela 1 0.11 0.86 0.59
53 INT184028 Protein_catabolism of Rela 4 0.40 2.12 0.57
54 INT185700 Gene_expression of G6pc 2 0.36 0.88 0.49
55 INT73559 Negative_regulation of Positive_regulation of RELA 2 0.36 1.37 0.49
56 INT177878 Positive_regulation of Gene_expression of MTHFD2 1 0.26 1.16 0.46
57 INT177882 Gene_expression of MTHFD2 1 0.40 1.16 0.46
58 INT168101 Positive_regulation of PTPRF 2 0.45 1.04 0.37
59 INT321335 Regulation of Regulation of G6pc 1 0.21 0.35 0.36
60 INT129934 Gene_expression of G6PC 3 0.57 5.3 0.35
61 INT349651 Positive_regulation of Gene_expression of Rela 1 0.03 1.46 0.33
62 INT73555 Negative_regulation of RELA 5 0.41 0.57 0.32
63 INT240822 Negative_regulation of Gene_expression of G6pc 5 0.35 2.17 0.31
64 INT95622 Regulation of Negative_regulation of G6pc 1 0.21 0 0.31
65 INT129297 Positive_regulation of Phosphorylation of RELA 1 0.24 0.33 0.29
66 INT273623 Regulation of Rela 7 0.14 4 0.28
67 INT212615 Localization of PTPRF 2 0.68 0.34 0.28
68 INT319704 Negative_regulation of Binding of Rela 1 0.05 0.51 0.26
69 INT170600 Negative_regulation of Gene_expression of RELA 16 0.39 1.29 0.25
70 INT170596 Regulation of RELA 4 0.41 0.39 0.25
71 INT162519 Regulation of Localization of Rela 3 0.20 1.78 0.25
72 INT37570 Localization of Otc 2 0.61 0.97 0.25
73 INT240840 Gene_expression of G6pc 6 0.63 2.55 0.23
74 INT170594 Regulation of Gene_expression of RELA 6 0.41 0.15 0.22
75 INT28031 Negative_regulation of Binding of Otc 1 0.43 0.36 0.22
76 INT184037 Positive_regulation of Protein_catabolism of Rela 1 0.20 0.34 0.22
77 INT169061 Gene_expression of Pnp 19 0.66 9.39 0.21
78 INT169062 Positive_regulation of Gene_expression of Pnp 6 0.49 3.6 0.21
79 INT170607 Positive_regulation of Positive_regulation of RELA 4 0.46 1.49 0.21
80 INT321308 Regulation of Gene_expression of G6pc 1 0.21 0.31 0.21
81 INT218583 Regulation of Positive_regulation of Rela 1 0.05 1.51 0.21
82 INT301526 Transcription of G6pc 1 0.23 1.97 0.21
83 INT170602 Positive_regulation of Binding of RELA 5 0.46 0.32 0.2
84 INT342400 Positive_regulation of Binding of Rela 1 0.30 0.5 0.19
85 INT153462 Regulation of Rela 1 0.44 0.98 0.15
86 INT96224 Positive_regulation of Ptprf 1 0.11 0.36 0.14
87 INT273621 Negative_regulation of Regulation of Rela 1 0.18 1.12 0.12
88 INT187313 Regulation of PTPRF 1 0.01 0 0.11
89 INT170597 Negative_regulation of Regulation of RELA 1 0.39 0 0.11
90 INT187312 Regulation of Positive_regulation of PTPRF 1 0.03 0 0.11
91 INT321302 Transcription of G6PC 1 0.69 0.07 0.1
92 INT169060 Negative_regulation of Gene_expression of Pnp 3 0.42 0.95 0.08
93 INT170593 Transcription of RELA 3 0.63 0.92 0.08
94 INT129935 Binding of G6PC 1 0.22 1.11 0.08
95 INT280709 Positive_regulation of Positive_regulation of Otc 1 0.37 0 0.08
96 INT294736 Positive_regulation of Positive_regulation of Rela 1 0.03 1.04 0.08
97 INT211097 Negative_regulation of Binding of Pnp 1 0.08 1.27 0.08
98 INT301551 Positive_regulation of Transcription of G6pc 1 0.22 0.64 0.08
99 INT248672 Binding of Rela 1 0.05 0.38 0.06
100 INT200100 Negative_regulation of Gene_expression of G6PC 1 0.05 0.54 0.06
101 INT218757 Regulation of Pnp 4 0.15 5.51 0.04
102 INT322348 Negative_regulation of Phosphorylation of Rela 2 0.19 1.41 0.03
103 INT240843 Regulation of G6pc 3 0.50 1.01 0
104 INT232066 Binding of PNP 3 0.13 0.28 0
105 INT232073 Regulation of PNP 2 0.12 0.33 0
106 INT186335 Protein_catabolism of RELA 2 0.86 0.71 0
107 INT174238 Positive_regulation of Gene_expression of PNP 2 0.16 0.69 0
108 INT280520 Regulation of Gene_expression of Pnp 1 0.15 0.55 0
109 INT312059 Negative_regulation of Binding of RELA 1 0.43 0 0
110 INT240921 Positive_regulation of Negative_regulation of G6pc 1 0.42 0.12 0
111 INT240820 Positive_regulation of G6pc 1 0.38 0.58 0
112 INT285458 Negative_regulation of Gene_expression of PNP 1 0.11 0 0
113 INT315236 Regulation of Negative_regulation of Rela 1 0.10 0.49 0
114 INT315226 Regulation of Gene_expression of Rela 1 0.10 1.03 0
115 INT285456 Positive_regulation of PNP 1 0.13 0.08 0
116 INT186330 Positive_regulation of Protein_catabolism of RELA 1 0.49 0.55 0
117 INT285457 Localization of PNP 1 0.21 0 0
118 INT278004 Localization of Ptprf 1 0.68 0.31 0
119 INT177852 Negative_regulation of Gene_expression of MTHFD2 1 0.22 0.4 0
120 INT320332 Transcription of Pnp 1 0.05 0.05 0
121 INT195532 Regulation of Binding of Rela 1 0.11 0 0
122 INT315223 Negative_regulation of Negative_regulation of Rela 1 0.10 0.48 0
123 INT302919 Negative_regulation of Regulation of Pnp 1 0.04 1.71 0
124 INT240824 Regulation of Gene_expression of G6pc 1 0.36 0.58 0
125 INT288036 Negative_regulation of Phosphorylation of RELA 1 0.07 0.13 0
126 INT315229 Regulation of Regulation of Rela 1 0.14 0.61 0
127 INT288035 Regulation of Binding of RELA 1 0.04 0 0
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