GO:0042307

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Name positive regulation of protein import into nucleus
Categary Process
Go Slim No
Go Link GO:0042307
Unique Molecular Interactions 390
Total Molecular Interactions 511
Total Single Events 2922
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein import into nucleus. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of protein import into nucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
2 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
3 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
4 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
5 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
6 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
7 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
8 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
9 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
10 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
11 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
12 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
13 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
14 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
15 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
16 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
17 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
18 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
19 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
20 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
21 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
22 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
23 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
24 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
25 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
26 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
27 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
28 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
29 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
30 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
31 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
32 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
33 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
34 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
35 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
36 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
37 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
38 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
39 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56
40 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
41 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
42 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55
43 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
44 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53
45 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53
46 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
47 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
48 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
49 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
50 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
51 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
52 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
53 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
54 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
55 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
56 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
57 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
58 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
59 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
60 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
61 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
62 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
63 INT213484 Binding of Lep and Pik3c3 1 0.01 0 0.35
64 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
65 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
66 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
67 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
68 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
69 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
70 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
71 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
72 INT303993 Lep Positive_regulation of Gene_expression of IL2 1 0.15 0.24 0.33
73 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
74 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
75 INT213485 Lep Positive_regulation of Localization of Grin2a 1 0.19 0 0.31
76 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
77 INT226989 Lias Regulation of Gene_expression of Lep 1 0.10 0.91 0.3
78 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
79 INT303983 Lep Positive_regulation of CXCL10 1 0.06 0.31 0.29
80 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29
81 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29
82 INT303998 Lep Positive_regulation of Localization of IL1RAPL1 1 0.04 0.31 0.29
83 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29
84 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
85 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
86 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
87 INT300552 Napa Positive_regulation of Gene_expression of TGFB1 1 0.01 0.88 0.29
88 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
89 INT303984 Lep Positive_regulation of Gene_expression of IL8 1 0.06 0.85 0.28
90 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
91 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
92 INT137032 Il6 Positive_regulation of Localization of Tgfb1 1 0.04 0.51 0.27
93 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
94 INT100531 Cck Positive_regulation of Lep 1 0.70 0.15 0.26
95 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
96 INT271450 Thy1 Regulation of TGFB1 1 0.00 0.62 0.25
97 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25
98 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
99 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24
100 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24
101 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
102 INT168710 Ifng Regulation of TGFB1 1 0.00 0.3 0.23
103 INT303988 Lep Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.55 0.23
104 INT102937 Gnrh1 Positive_regulation of Gene_expression of Lep 1 0.50 0 0.22
105 INT112596 Tgfb1 Negative_regulation of Negative_regulation of Mptp1 1 0.26 0.72 0.22
106 INT112595 Tgfb1 Negative_regulation of Gene_expression of Mptp1 1 0.27 0.72 0.22
107 INT110653 Lep Regulation of Localization of Cck 1 0.06 0.22 0.22
108 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21
109 INT207185 Binding of Bmi1 and Lep 1 0.01 1.7 0.21
110 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21
111 INT114905 TGFB1 Positive_regulation of Transcription of COL7A1 1 0.02 0.08 0.21
112 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2
113 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2
114 INT304001 Lep Negative_regulation of ICAM3 1 0.07 0.35 0.2
115 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
116 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2
117 INT92692 Tgfb1 Positive_regulation of Gene_expression of Fn1 1 0.27 0.91 0.2
118 INT303979 Lep Positive_regulation of ITGB2 1 0.11 0.35 0.2
119 INT256576 Lep Regulation of Localization of Ins1 1 0.57 2.08 0.2
120 INT303991 Lep Negative_regulation of SELL 1 0.04 0.35 0.2
121 INT92693 Tgfb1 Positive_regulation of Fgf2 1 0.32 0.9 0.2
122 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
123 INT280260 Tgfb1 Positive_regulation of Cxcr1 1 0.07 1.78 0.19
124 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19
125 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19
126 INT303964 Lep Positive_regulation of Icam1 1 0.24 0.35 0.19
127 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
128 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
129 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
130 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
131 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19
132 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
133 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
134 INT280261 Tgfb1 Positive_regulation of Gene_expression of Cxcr1 1 0.05 1.81 0.19
135 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19
136 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19
137 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18
138 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
139 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18
140 INT303981 Lep Positive_regulation of Localization of CXCL1 1 0.02 0.34 0.18
141 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18
142 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
143 INT226988 Lias Positive_regulation of Localization of Lep 1 0.08 0.3 0.17
144 INT85334 Agtr2 Regulation of Regulation of Tgfb1 1 0.23 0.68 0.17
145 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17
146 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16
147 INT160083 TGFB1 Positive_regulation of Gene_expression of L1CAM 1 0.16 1.53 0.16
148 INT303980 Lep Positive_regulation of Transcription of IL2 1 0.10 0.24 0.16
149 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
150 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14
151 INT299550 TGFB1 Negative_regulation of Glul 1 0.01 0.34 0.14
152 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13
153 INT296031 Negative_regulation of TGFB1 Regulation of IL10 1 0.01 1.01 0.13
154 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
155 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
156 INT296027 TGFB1 Regulation of TH1L 1 0.02 1 0.13
157 INT299547 Negative_regulation of Binding of TGFB1 and Egf 1 0.02 0.1 0.13
158 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
159 INT69687 Tgfb1 Positive_regulation of Gene_expression of Il4 1 0.23 0 0.12
160 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12
161 INT214141 Binding of Lep and Lepr 1 0.32 0.82 0.12
162 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12
163 INT296028 TGFB1 Regulation of IL10 1 0.01 1 0.12
164 INT69688 Tgfb1 Positive_regulation of Rel 1 0.50 0 0.12
165 INT294742 Lep Positive_regulation of Localization of Icam1 1 0.15 0.48 0.11
166 INT163817 Lep Positive_regulation of Phosphorylation of Akt1 1 0.33 0.31 0.11
167 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11
168 INT303989 Lep Positive_regulation of IL12A 1 0.05 0.39 0.11
169 INT296038 TGFB1 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11
170 INT299551 Regulation of Binding of TGFB1 and Egf 1 0.03 0.21 0.11
171 INT300313 TGFB1 Positive_regulation of Mapk14 1 0.01 1.5 0.11
172 INT303966 Lep Regulation of Il1 2 0.09 0.41 0.1
173 INT303990 Binding of Lep and Positive_regulation of Gene_expression of LPL 1 0.03 0.35 0.1
174 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1
175 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
176 INT304000 Lep Negative_regulation of Positive_regulation of CASP8 1 0.04 0.25 0.1
177 INT123864 Lep Positive_regulation of Positive_regulation of Cck 1 0.45 0.1 0.09
178 INT242324 Lep Regulation of Gene_expression of Ucp1 1 0.58 1.47 0.09
179 INT142418 Lep Positive_regulation of Gene_expression of Ghrl 1 0.48 1.66 0.09
180 INT299555 Lifr Positive_regulation of Gene_expression of TGFB1 1 0.03 0.23 0.09
181 INT213482 Lep Positive_regulation of Mapk1 1 0.06 0.08 0.09
182 INT116789 Bsg Positive_regulation of Gene_expression of Tgfb1 1 0.00 0.18 0.09
183 INT127143 Binding of IL6 and TGFB1 2 0.01 0.16 0.08
184 INT296041 Binding of TGFB1 and IL21 1 0.01 0.05 0.08
185 INT134832 TGFB1 Regulation of YAP1 1 0.16 0.68 0.08
186 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
187 INT134837 TGFB1 Regulation of SMAD7 1 0.34 0.68 0.08
188 INT222545 Lep Negative_regulation of Nmb 1 0.04 0.52 0.08
189 INT123866 Lep Negative_regulation of Olfr544 1 0.00 0.09 0.08
190 INT134833 TGFB1 Regulation of Gene_expression of SMAD7 1 0.34 0.69 0.08
191 INT303999 Lep Positive_regulation of Gene_expression of ITGA2 1 0.06 0.29 0.08
192 INT304330 TGFB1 Positive_regulation of ECM1 1 0.00 0.31 0.08
193 INT251232 Slc17a6 Positive_regulation of Tgfb1 1 0.03 0 0.08
194 INT134835 TGFB1 Regulation of Gene_expression of YAP1 1 0.49 0.69 0.08
195 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
196 INT268325 Lep Positive_regulation of Ptgs2 1 0.09 0.39 0.08
197 INT134834 TGFB1 Positive_regulation of YAP1 1 0.55 0.81 0.08
198 INT303970 Lep Positive_regulation of Gene_expression of Itga2 1 0.09 0.29 0.08
199 INT134838 TGFB1 Positive_regulation of SMAD7 1 0.52 0.79 0.08
200 INT294743 Lep Positive_regulation of Transcription of Il6 1 0.18 0.42 0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein import into nucleus. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of protein import into nucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
2 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
3 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
4 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
5 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
6 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
7 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
8 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
9 INT73641 Regulation of Lep 45 0.62 26.2 12.59
10 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
11 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
12 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
13 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
14 INT82082 Localization of Lep 63 0.81 26.41 8.56
15 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
16 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
17 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
18 INT91338 Binding of Lep 31 0.48 26.86 5.39
19 INT102935 Regulation of Lep 31 0.60 18.47 5.24
20 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
21 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
22 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
23 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
24 INT97391 Binding of Lep 18 0.48 8.97 4.47
25 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
26 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
27 INT163581 Localization of Lep 27 0.79 18.99 4.08
28 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
29 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
30 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
31 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
32 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
33 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
34 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
35 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
36 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
37 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
38 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
39 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
40 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
41 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
42 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
43 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
44 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
45 INT83392 Transcription of Lep 6 0.54 5.07 2.04
46 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
47 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
48 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
49 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
50 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
51 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
52 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
53 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
54 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
55 INT140245 Binding of Gli3 3 0.36 2.65 1.46
56 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44
57 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
58 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
59 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
60 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
61 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19
62 INT213465 Transcription of Lep 4 0.68 2.11 1.15
63 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
64 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12
65 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
66 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
67 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
68 INT242171 Protein_catabolism of JUP 4 0.96 0.91 1.01
69 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
70 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
71 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
72 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
73 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
74 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
75 INT333883 Positive_regulation of Positive_regulation of Lep 2 0.46 1.06 0.83
76 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
77 INT270447 Binding of Smo 2 0.07 2.61 0.78
78 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
79 INT291617 Negative_regulation of Transcription of TGFB1 2 0.15 0.61 0.76
80 INT90790 Regulation of Localization of Tgfb1 2 0.29 0.46 0.75
81 INT213471 Positive_regulation of Localization of Lep 4 0.48 2.65 0.74
82 INT337046 Positive_regulation of Binding of Tgfb1 1 0.30 1.1 0.69
83 INT68560 Regulation of Gli3 3 0.18 1.51 0.68
84 INT121302 Positive_regulation of Localization of Tgfb1 5 0.07 1.91 0.67
85 INT114909 Negative_regulation of Localization of TGFB1 5 0.36 1.37 0.66
86 INT111891 Regulation of Transcription of Tgfb1 1 0.04 0.68 0.64
87 INT101484 Regulation of Positive_regulation of Lep 3 0.45 1.68 0.61
88 INT205957 Negative_regulation of Smo 4 0.08 2.57 0.6
89 INT114910 Negative_regulation of Positive_regulation of TGFB1 3 0.34 0.92 0.6
90 INT345957 Positive_regulation of Binding of Lep 2 0.38 2.03 0.6
91 INT83391 Negative_regulation of Transcription of Lep 1 0.43 0.34 0.6
92 INT173891 Positive_regulation of Phosphorylation of TGFB1 4 0.49 2 0.59
93 INT138140 Protein_catabolism of Tgfb1 2 0.09 0.87 0.59
94 INT69683 Positive_regulation of Transcription of Tgfb1 1 0.67 0 0.53
95 INT135062 Transcription of Gli3 1 0.05 0 0.52
96 INT266535 Phosphorylation of JUP 3 0.79 0.63 0.49
97 INT242168 Transcription of JUP 4 0.67 1.17 0.46
98 INT206484 Localization of Shh 2 0.75 1.14 0.46
99 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
100 INT102934 Positive_regulation of Regulation of Lep 2 0.50 0.55 0.42
101 INT323765 Negative_regulation of Binding of Lep 1 0.37 0.91 0.42
102 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
103 INT69680 Positive_regulation of Positive_regulation of Tgfb1 3 0.67 1.04 0.35
104 INT242169 Positive_regulation of Protein_catabolism of JUP 1 0.49 0.23 0.34
105 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32
106 INT303962 Phosphorylation of Lep 2 0.80 5.2 0.31
107 INT213467 Negative_regulation of Localization of Lep 2 0.40 1.11 0.31
108 INT356400 Transcription of Smo 1 0.02 0.05 0.3
109 INT277474 Positive_regulation of Gene_expression of SMO 1 0.11 0 0.29
110 INT216120 Negative_regulation of SMO 2 0.49 3.05 0.27
111 INT221860 Negative_regulation of Jup 9 0.15 6.82 0.26
112 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
113 INT212388 Gene_expression of Zic1 2 0.40 0.3 0.25
114 INT135061 Protein_catabolism of Gli3 1 0.04 0 0.25
115 INT251228 Phosphorylation of Tgfb1 4 0.15 1.18 0.24
116 INT142417 Positive_regulation of Transcription of Lep 2 0.52 2.63 0.22
117 INT299545 Positive_regulation of Binding of TGFB1 2 0.06 1.08 0.22
118 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
119 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
120 INT234903 Gene_expression of Jup 1 0.23 7.1 0.2
121 INT135060 Negative_regulation of Transcription of Gli3 1 0.03 0 0.19
122 INT163816 Phosphorylation of Lep 2 0.63 2.2 0.17
123 INT85330 Positive_regulation of Regulation of Tgfb1 1 0.41 0.67 0.17
124 INT333880 Protein_catabolism of Lep 1 0.65 0.34 0.17
125 INT122201 Binding of Tgfb1 1 0.16 0.17 0.17
126 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
127 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
128 INT333882 Regulation of Binding of Lep 1 0.45 0.07 0.16
129 INT133100 Negative_regulation of Localization of Tgfb1 2 0.28 1.48 0.15
130 INT205083 Positive_regulation of JUP 6 0.49 5.51 0.13
131 INT253190 Localization of Shh 2 0.77 1.06 0.13
132 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
133 INT163815 Negative_regulation of Negative_regulation of Lep 1 0.43 0.32 0.12
134 INT226984 Regulation of Transcription of Lep 1 0.27 0.3 0.11
135 INT270451 Localization of Gli3 1 0.26 0.63 0.11
136 INT14738 Negative_regulation of Regulation of TGFB1 2 0.41 0.81 0.09
137 INT242173 Positive_regulation of Gene_expression of JUP 2 0.49 2.37 0.09
138 INT270442 Transcription of Shh 1 0.53 0.25 0.09
139 INT135063 Regulation of Gene_expression of Gli3 1 0.04 0 0.09
140 INT213515 Binding of Shh 8 0.37 1.92 0.08
141 INT309877 Localization of JUP 2 0.73 1.38 0.08
142 INT331623 Negative_regulation of Binding of TGFB1 1 0.02 1.02 0.08
143 INT339206 Negative_regulation of Localization of JUP 1 0.41 1.1 0.08
144 INT270453 Regulation of Shh 1 0.27 0.83 0.08
145 INT234894 Negative_regulation of Protein_catabolism of Jup 1 0.17 2.87 0.08
146 INT126375 Negative_regulation of Gene_expression of Gli3 1 0.58 0.79 0.08
147 INT205973 Binding of SHH 3 0.35 1.03 0.07
148 INT213475 Negative_regulation of Positive_regulation of Lep 2 0.40 1.79 0.07
149 INT256862 Regulation of Shh 1 0.25 0 0.07
150 INT234866 Regulation of Jup 2 0.08 0.58 0.06
151 INT213466 Negative_regulation of Regulation of Lep 1 0.41 0 0.06
152 INT139093 Regulation of Negative_regulation of Tgfb1 1 0.27 0.44 0.06
153 INT234899 Positive_regulation of Protein_catabolism of Jup 1 0.21 0.88 0.06
154 INT345344 Regulation of SMO 1 0.23 1.07 0.06
155 INT329585 Regulation of Negative_regulation of Jup 1 0.01 0.23 0.06
156 INT234931 Protein_catabolism of Jup 1 0.29 2.23 0.06
157 INT234915 Positive_regulation of Gene_expression of Jup 1 0.15 2.7 0.06
158 INT251230 Positive_regulation of Negative_regulation of Tgfb1 1 0.09 0 0.05
159 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
160 INT136115 Positive_regulation of Regulation of TGFB1 1 0.11 0.16 0.05
161 INT262772 Binding of SMO 1 0.27 0.59 0.05
162 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
163 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
164 INT262777 Localization of SMO 1 0.59 0.6 0.04
165 INT185020 Positive_regulation of Negative_regulation of TGFB1 1 0.43 0.44 0.04
166 INT180881 Regulation of Positive_regulation of TGFB1 2 0.32 1.32 0.03
167 INT234890 Phosphorylation of Jup 1 0.24 1.56 0.03
168 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
169 INT234867 Localization of Jup 1 0.24 2.84 0.03
170 INT253181 Transcription of Shh 1 0.68 0.54 0.03
171 INT266537 Positive_regulation of Phosphorylation of JUP 2 0.49 0.29 0
172 INT253406 Negative_regulation of Positive_regulation of Lep 2 0.41 0.74 0
173 INT266534 Negative_regulation of Phosphorylation of JUP 2 0.41 0.15 0
174 INT242174 Negative_regulation of Gene_expression of JUP 2 0.41 2.58 0
175 INT221864 Binding of JUP 2 0.36 1.05 0
176 INT221859 Binding of Jup 2 0.14 2.21 0
177 INT150408 Regulation of Regulation of Lep 1 0.27 0 0
178 INT309874 Positive_regulation of Binding of JUP 1 0.49 0.32 0
179 INT305226 Negative_regulation of Phosphorylation of Lep 1 0.42 1.89 0
180 INT305239 Positive_regulation of Phosphorylation of Lep 1 0.43 1.09 0
181 INT252242 Gene_expression of Smo 1 0.01 0.23 0
182 INT133097 Positive_regulation of Phosphorylation of Tgfb1 1 0.05 0.07 0
183 INT234877 Positive_regulation of Binding of Jup 1 0.21 0.24 0
184 INT242170 Negative_regulation of JUP 1 0.42 0.85 0
185 INT212407 Binding of Zic1 1 0.26 0.31 0
186 INT254788 Negative_regulation of Regulation of Tgfb1 1 0.06 0.61 0
187 INT332954 Regulation of Transcription of Lep 1 0.11 1.4 0
188 INT254800 Positive_regulation of Phosphorylation of Tgfb1 1 0.04 0.24 0
189 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
190 INT133099 Negative_regulation of Phosphorylation of Tgfb1 1 0.04 0.08 0
191 INT174279 Positive_regulation of Negative_regulation of Lep 1 0.46 0.16 0
192 INT133098 Phosphorylation of Tgfb1 1 0.06 0.07 0
193 INT128712 Positive_regulation of Regulation of Tgfb1 1 0.15 0 0
194 INT309421 Positive_regulation of Regulation of Lep 1 0.41 0.61 0
195 INT309876 Regulation of JUP 1 0.60 0.67 0
196 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
197 INT205956 Localization of Smo 1 0.06 0.71 0
198 INT234918 Positive_regulation of Jup 1 0.15 1.08 0
199 INT288213 Positive_regulation of Negative_regulation of Lep 1 0.47 0.06 0
200 INT290929 Binding of Shh 1 0.31 0.1 0
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