GO:0042312

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Name regulation of vasodilation
Categary Process
Go Slim No
Go Link GO:0042312
Unique Molecular Interactions 184
Total Molecular Interactions 273
Total Single Events 3793
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of vasodilation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of vasodilation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT107812 Nppa Positive_regulation of Localization of Sst 1 0.48 0.54 2.51
2 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
3 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
4 INT107815 Gene_expression of Sst Positive_regulation of Localization of Nppa 1 0.52 0.27 1.57
5 INT107813 Sst Negative_regulation of Localization of Nppa 1 0.44 0.2 1.46
6 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
7 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
8 INT31771 Penk Positive_regulation of Nppa 1 0.22 0.13 1.28
9 INT31773 Pdyn Positive_regulation of Nppa 1 0.12 0.13 1.27
10 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
11 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
12 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
13 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
14 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
15 INT215648 Binding of Adora1 and Gabrd 1 0.03 0.06 1.16
16 INT24796 ACE Positive_regulation of Localization of HMMR 1 0.00 0.58 1.16
17 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
18 INT320021 Prkaca Regulation of Positive_regulation of Kcnma1 1 0.00 0.54 1
19 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99
20 INT128602 Binding of Kcnma1 and Gtf2ird2 1 0.00 0 0.97
21 INT258170 Binding of Adora1 and Ppap2a 1 0.05 0.26 0.94
22 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92
23 INT112642 Positive_regulation of Kcnma1 Positive_regulation of Nav1 1 0.02 0 0.89
24 INT215646 Binding of Adora1 and P2rx2 1 0.13 0.51 0.85
25 INT60102 Adora1 Regulation of Localization of Calca 1 0.46 0 0.79
26 INT166902 NPPB Positive_regulation of TRPA1 1 0.78 0.76 0.77
27 INT107810 Sst Positive_regulation of Localization of Nppa 1 0.42 0.14 0.77
28 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75
29 INT216654 Binding of P2ry2 and DRGX 1 0.01 1.59 0.71
30 INT216644 Binding of P2ry1 and P2ry2 1 0.24 0.55 0.64
31 INT16412 Nppa Negative_regulation of Localization of LH 2 0.41 0.29 0.62
32 INT215647 Adora1 Positive_regulation of Kcnj5 1 0.00 0 0.62
33 INT21607 ACE Positive_regulation of ANGPT2 1 0.03 0.13 0.61
34 INT147049 CB Positive_regulation of Nppa 1 0.02 1.01 0.6
35 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58
36 INT101216 Pnoc Positive_regulation of Localization of Nppa 1 0.68 0.09 0.57
37 INT147040 Hmbs Negative_regulation of Nppa 1 0.07 0.95 0.55
38 INT107814 Nppa Positive_regulation of Positive_regulation of Sst 1 0.42 0.16 0.55
39 INT16643 Nppa Regulation of Rabep2 1 0.13 0.07 0.55
40 INT311256 Nt5e Positive_regulation of Positive_regulation of Adora1 1 0.49 0.19 0.54
41 INT308894 Adp Regulation of P2ry1 1 0.05 0.49 0.53
42 INT330796 P2ry1 Positive_regulation of Ca2 1 0.05 0.06 0.5
43 INT308892 Adp Positive_regulation of P2ry1 1 0.11 0.44 0.47
44 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
45 INT16413 Nppa Regulation of Localization of LH 1 0.43 0.76 0.45
46 INT191489 Positive_regulation of P2ry2 Negative_regulation of Positive_regulation of Trpv1 1 0.03 0.08 0.44
47 INT215564 Hmmr Negative_regulation of P2ry2 1 0.00 0 0.44
48 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43
49 INT25430 Gtf3a Regulation of Nppa 1 0.24 0.57 0.43
50 INT215651 Binding of Adora1 and Cpa1 1 0.00 0 0.42
51 INT79486 Nppa Negative_regulation of NA 1 0.03 1.83 0.41
52 INT131356 Binding of Nppa and Npr1 1 0.27 1.73 0.4
53 INT182489 Gene_expression of AGTR2 Positive_regulation of Gene_expression of AGTR1 1 0.26 0.92 0.4
54 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39
55 INT229222 Negative_regulation of ACE Negative_regulation of Protein_catabolism of KNG1 1 0.06 0.53 0.37
56 INT32698 Nppa Regulation of Oxt 1 0.57 0.35 0.35
57 INT32699 Nppa Regulation of Avp 1 0.28 0.35 0.35
58 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
59 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32
60 INT166901 NPPB Positive_regulation of Gene_expression of TRPA1 1 0.68 0.33 0.3
61 INT147041 Hmbs Negative_regulation of Negative_regulation of Nppa 1 0.05 0.51 0.3
62 INT30706 Nppa Positive_regulation of Localization of AVP 1 0.78 0.45 0.3
63 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3
64 INT258857 Binding of P2rx1 and P2ry2 1 0.22 0.81 0.29
65 INT215645 Binding of Adora1 and Kcnj5 1 0.00 0.08 0.29
66 INT215683 P2ry2 Positive_regulation of Gene_expression of Il6 1 0.02 0.76 0.29
67 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28
68 INT215653 Binding of Adora1 and Adora3 1 0.39 0.07 0.27
69 INT136245 Gucy1a2 Positive_regulation of Nppa 1 0.06 0.22 0.27
70 INT258856 P2ry2 Positive_regulation of P9Ehs1 1 0.01 0.76 0.26
71 INT136246 Gucy1a2 Negative_regulation of Nppa 1 0.05 0.22 0.26
72 INT20587 Nppa Positive_regulation of Gfra1 1 0.02 0.32 0.26
73 INT180718 Binding of SARS and ACE2 3 0.12 7.76 0.25
74 INT165478 Prok2 Positive_regulation of Positive_regulation of Kcnma1 1 0.02 0 0.25
75 INT308893 P2ry1 Positive_regulation of Adp 1 0.12 0 0.25
76 INT215652 Binding of Adora1 and Npy1r 1 0.39 0.22 0.24
77 INT191500 ACE Positive_regulation of Localization of KNG1 1 0.10 0.17 0.24
78 INT109845 Binding of P2RX3 and P2RY1 1 0.38 0 0.24
79 INT32636 Slc12a3 Regulation of Localization of Nppa 1 0.00 0.41 0.23
80 INT170158 NPPA Positive_regulation of Gene_expression of NPPB 1 0.13 0.91 0.23
81 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
82 INT265828 ACE Regulation of Gene_expression of KNG1 1 0.32 0.83 0.22
83 INT32565 Nppa Regulation of Localization of CGA 1 0.00 0.07 0.22
84 INT131354 Npr1 Regulation of Nppa 1 0.40 0.88 0.22
85 INT242245 Binding of P2ry1 and Adp 1 0.00 0.31 0.21
86 INT167113 Binding of P2ry1 and Trpv1 1 0.40 0 0.21
87 INT242250 Binding of P2ry1 and P2ry12 1 0.01 0.3 0.21
88 INT216705 Binding of MARS and P2RY1 1 0.06 0 0.2
89 INT21171 Nppa Regulation of Ren 1 0.35 0.35 0.19
90 INT32700 Nppa Negative_regulation of Oxt 1 0.40 0.16 0.19
91 INT32696 Nppa Negative_regulation of Avp 1 0.45 0.16 0.19
92 INT32697 Nppa Negative_regulation of Gene_expression of Oxt 1 0.40 0.16 0.19
93 INT32494 Nppa Negative_regulation of Localization of Avp 1 0.28 1.16 0.18
94 INT323757 Negative_regulation of ACE2 Negative_regulation of ANG 1 0.18 1.73 0.17
95 INT323756 Negative_regulation of ACE2 Positive_regulation of ANG 1 0.19 1.73 0.17
96 INT216487 Ca2 Negative_regulation of Kcnma1 1 0.00 0.1 0.17
97 INT265827 ACE Negative_regulation of ANGPT2 1 0.09 0.59 0.17
98 INT352290 Binding of Agtr1a and P2ry1 1 0.00 0 0.16
99 INT216711 P2RY1 Negative_regulation of P2RY12 1 0.28 0.09 0.16
100 INT30705 Nppa Negative_regulation of Localization of AVP 1 0.48 0.22 0.15
101 INT251435 Gnat3 Positive_regulation of NPR1 1 0.22 0.2 0.15
102 INT75058 Negative_regulation of ACE Negative_regulation of HHIP 1 0.25 0.43 0.15
103 INT277012 Binding of PAPPA and ACE2 1 0.02 1.26 0.15
104 INT249322 Positive_regulation of Adora1 Regulation of Rit2 1 0.10 0 0.14
105 INT56181 sch Regulation of Positive_regulation of Nppa 1 0.07 0.08 0.14
106 INT344946 AGT Regulation of Negative_regulation of ACE 1 0.21 0.61 0.14
107 INT102885 Binding of ANG and ACE 2 0.17 0.37 0.13
108 INT108598 Positive_regulation of Oprl1 Positive_regulation of Phosphorylation of P2ry2 1 0.10 0 0.13
109 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13
110 INT329317 ACE Regulation of Positive_regulation of KNG1 1 0.02 1.05 0.12
111 INT224040 Mtpn Positive_regulation of P2RY1 1 0.00 0.85 0.12
112 INT329325 ACE Regulation of Negative_regulation of Agtr2 1 0.01 0.93 0.12
113 INT249321 Positive_regulation of Adora1 Regulation of Preb 1 0.20 0.09 0.12
114 INT184608 APC Regulation of Gene_expression of Nppa 1 0.06 1.11 0.12
115 INT71755 Nppa Regulation of Localization of Alb 1 0.25 1.29 0.11
116 INT7302 Binding of NPPA and Nppa 1 0.13 1.25 0.11
117 INT208983 Binding of Ca2 and Kcnma1 2 0.01 0.28 0.1
118 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1
119 INT336990 Binding of AGTR1 and BDKRB2 1 0.03 0 0.1
120 INT5627 Tfpi Positive_regulation of Localization of Nppa 1 0.31 0.07 0.1
121 INT5626 Tfpi Positive_regulation of Transcription of Nppa 1 0.31 0.07 0.1
122 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09
123 INT252421 Gja1 Regulation of P2ry1 1 0.00 0.28 0.09
124 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09
125 INT279707 Positive_regulation of AGTR1 Regulation of TYRP1 1 0.00 0 0.09
126 INT279706 Positive_regulation of AGTR1 Regulation of TRPC6 1 0.00 0 0.09
127 INT344945 Negative_regulation of ACE Positive_regulation of REN 1 0.23 0.64 0.09
128 INT9086 Binding of Nppa and Nppb 1 0.35 0.19 0.08
129 INT215767 Binding of P2ry1 and Ca2 1 0.02 0.2 0.08
130 INT26310 IL1B Positive_regulation of ACE2 1 0.18 0.46 0.07
131 INT281900 Positive_regulation of Binding of AGT and AGTR1 1 0.12 0.16 0.07
132 INT51719 Nppa Regulation of Regulation of Pomc 1 0.14 0.1 0.07
133 INT200634 Binding of Agtr2 and Ace2 1 0.00 0.91 0.06
134 INT200641 Binding of ACE and Agtr1a 1 0.12 0.92 0.06
135 INT216570 Gene_expression of cx Positive_regulation of Kcnma1 1 0.00 0.25 0.06
136 INT281909 Binding of AGT and AGTR1 1 0.09 0.16 0.06
137 INT216545 Gene_expression of Cftr Negative_regulation of Kcnma1 1 0.00 0.59 0.06
138 INT200638 Binding of ACE and Agtr2 1 0.10 0.93 0.06
139 INT16414 Nppa Regulation of Nppb 1 0.24 0.26 0.05
140 INT222512 Nppa Positive_regulation of Localization of LH 1 0.02 0 0.05
141 INT323755 IGHG3 Negative_regulation of ACE2 1 0.01 1.09 0.05
142 INT246206 Binding of P2ry2 and P2ry4 1 0.12 0 0.05
143 INT273068 Binding of P2RY2 and TFAP4 1 0.01 0.27 0.05
144 INT336132 Binding of AGTR1 and ANG 1 0.00 0.38 0.05
145 INT29521 Ace Positive_regulation of ACE 1 0.19 0 0.04
146 INT288595 Binding of CYTIP and Kcnma1 1 0.00 0 0.04
147 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04
148 INT323286 CYP4A11 Positive_regulation of Kcnma1 1 0.01 0.45 0.04
149 INT283226 Binding of ACE and CC2D1A 1 0.11 2.37 0.04
150 INT158391 Oxt Positive_regulation of Localization of Nppa 2 0.27 0.64 0.03
151 INT351915 P2ry1 Regulation of Gfm1 1 0.01 0.86 0.03
152 INT351914 P2ry1 Regulation of Gene_expression of Gfm1 1 0.01 0.86 0.03
153 INT215691 Binding of P2ry2 and P2rx3 1 0.08 0.46 0.03
154 INT215765 Binding of P2ry1 and P2ry2 1 0.07 0.46 0.03
155 INT215684 Binding of P2ry2 and P2rx4 1 0.06 0.46 0.03
156 INT177671 Vmn1r51 Positive_regulation of Localization of Nppa 1 0.01 0.24 0.03
157 INT100747 Kcnma1 Positive_regulation of sar 1 0.03 0 0
158 INT288584 Cav1 Regulation of Gene_expression of Kcnma1 1 0.14 0 0
159 INT288594 Regulation of Binding of CAV1 and Kcnma1 1 0.01 0 0
160 INT14790 Nppa Regulation of Edn3 1 0.45 0.7 0
161 INT233504 Tlr4 Regulation of P2ry2 1 0.04 0.07 0
162 INT14792 Edn3 Regulation of Nppa 1 0.17 0.17 0
163 INT288587 Cav1 Regulation of Binding of Kcnma1 1 0.14 0 0
164 INT256210 NPPB Regulation of PVR 1 0.24 1.14 0
165 INT288597 Binding of CAV1 and Kcnma1 1 0.01 0.17 0
166 INT288596 Positive_regulation of Binding of CAV1 and Kcnma1 1 0.01 0.1 0
167 INT233500 Tlr4 Negative_regulation of P2ry1 1 0.06 0.18 0
168 INT288593 Cav1 Positive_regulation of Binding of Kcnma1 1 0.15 0 0
169 INT165146 Kiss1 Regulation of Nppa 1 0.42 0 0
170 INT180749 Binding of Pmel and ACE2 1 0.20 2.14 0
171 INT288591 Cav1 Positive_regulation of Kcnma1 1 0.15 0 0
172 INT11122 Nppa Negative_regulation of Thop1 1 0.20 0.4 0
173 INT333044 Positive_regulation of Binding of AGTR1 and Trpv4 1 0.48 0 0
174 INT333045 Binding of AGTR1 and Gopc 1 0.05 0 0
175 INT288586 Cav1 Positive_regulation of Regulation of Kcnma1 1 0.21 0 0
176 INT288583 Negative_regulation of Binding of Cav1 and Kcnma1 1 0.13 0 0
177 INT200488 Binding of ACE and SUGT1 1 0.01 0.28 0
178 INT288589 Cav1 Regulation of Kcnma1 1 0.19 0.05 0
179 INT256211 NPPB Regulation of PDAP1 1 0.28 1.14 0
180 INT333043 Binding of AGTR1 and Trpv4 1 0.50 0 0
181 INT213584 Binding of AGTR2 and ACE 1 0.17 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of vasodilation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of vasodilation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5617 Localization of Nppa 266 0.81 83.51 83.89
2 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
3 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33
4 INT5620 Positive_regulation of Localization of Nppa 105 0.70 30.23 36.45
5 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03
6 INT6196 Regulation of Nppa 83 0.62 30.31 30.18
7 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56
8 INT8205 Negative_regulation of Nppa 77 0.59 26.43 25.72
9 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31
10 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19
11 INT37889 Gene_expression of P2ry2 75 0.65 26.01 23.8
12 INT5618 Regulation of Localization of Nppa 36 0.62 13.42 17.46
13 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01
14 INT61635 Positive_regulation of P2ry2 35 0.56 12.08 14.68
15 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19
16 INT69166 Positive_regulation of P2ry1 35 0.67 8.41 13.63
17 INT14764 Negative_regulation of Localization of Nppa 28 0.59 11.29 12.82
18 INT93122 Gene_expression of P2ry1 32 0.75 11.82 11.42
19 INT19155 Binding of Adora1 25 0.47 6.41 10.72
20 INT7458 Negative_regulation of Kcnma1 30 0.43 6.61 10.4
21 INT105816 Gene_expression of P2RY2 53 0.78 16.47 9.67
22 INT20664 Binding of ACE 60 0.48 35.27 9.16
23 INT114406 Gene_expression of Adora1 28 0.72 6.83 9.13
24 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81
25 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31
26 INT101699 Regulation of Adora1 14 0.61 3.7 7.59
27 INT111680 Gene_expression of P2ry2 20 0.58 9.23 7.39
28 INT76253 Positive_regulation of P2RY2 29 0.70 13.99 7.33
29 INT83006 Gene_expression of AGTR1 59 0.75 54.46 7.27
30 INT6210 Binding of Nppa 39 0.47 14.35 7.21
31 INT40159 Negative_regulation of Adora1 13 0.51 3.51 7.13
32 INT42038 Localization of ACE 26 0.80 8.88 7.06
33 INT9167 Binding of Adora1 6 0.40 0.53 6.9
34 INT95466 Regulation of P2ry2 23 0.56 3.66 6.86
35 INT6565 Positive_regulation of Positive_regulation of Nppa 14 0.70 4.04 6.76
36 INT62950 Gene_expression of NPPB 73 0.75 65.91 6.54
37 INT95170 Localization of P2ry1 10 0.78 5.08 5.63
38 INT111683 Gene_expression of P2ry1 22 0.74 7.96 5.59
39 INT102891 Positive_regulation of AGTR1 31 0.67 30.57 5.29
40 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15
41 INT139238 Positive_regulation of P2ry1 19 0.60 9.22 5.15
42 INT13051 Regulation of Kcnma1 12 0.12 2.09 5.06
43 INT109848 Gene_expression of P2RY1 26 0.62 6.71 4.98
44 INT65509 Regulation of P2ry1 13 0.60 2.38 4.96
45 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78
46 INT5624 Transcription of Nppa 19 0.69 8.52 4.72
47 INT5619 Positive_regulation of Gene_expression of Nppa 21 0.70 11.95 4.41
48 INT112038 Positive_regulation of P2ry2 8 0.45 2.41 4.4
49 INT26477 Regulation of ACE 26 0.45 16.31 4.33
50 INT1722 Protein_catabolism of ACE 10 0.88 2.61 3.76
51 INT65527 Positive_regulation of Positive_regulation of Adora1 4 0.46 0.67 3.71
52 INT159472 Localization of NPPB 32 0.79 33.67 3.59
53 INT215604 Localization of Adora1 10 0.78 1.47 3.49
54 INT118270 Regulation of P2RY2 16 0.45 7.02 3.45
55 INT126560 Binding of P2RY2 12 0.44 6.43 3.4
56 INT102347 Localization of P2ry2 4 0.56 1.23 3.31
57 INT48902 Gene_expression of ACE2 22 0.78 17.91 3.24
58 INT38030 Positive_regulation of P2RY1 15 0.67 5.54 3.17
59 INT6193 Regulation of Gene_expression of Nppa 6 0.45 2.02 2.93
60 INT54178 Regulation of Adora1 5 0.39 0.29 2.85
61 INT215608 Negative_regulation of Binding of Adora1 5 0.41 1.35 2.73
62 INT215521 Negative_regulation of P2ry1 10 0.56 2.68 2.72
63 INT91284 Negative_regulation of P2ry2 8 0.25 2.66 2.71
64 INT215601 Regulation of Positive_regulation of Adora1 9 0.60 1.74 2.66
65 INT215599 Positive_regulation of Positive_regulation of Adora1 7 0.47 2.29 2.58
66 INT91471 Positive_regulation of Gene_expression of Kcnma1 4 0.22 2.88 2.56
67 INT114020 Gene_expression of Adora1 2 0.33 4.24 2.55
68 INT107846 Transcription of P2ry2 6 0.46 2.06 2.52
69 INT26205 Positive_regulation of Positive_regulation of NPR1 3 0.24 1.57 2.52
70 INT20498 Negative_regulation of Positive_regulation of Nppa 9 0.59 4.5 2.43
71 INT150465 Positive_regulation of Gene_expression of P2ry2 3 0.56 3.48 2.33
72 INT11065 Gene_expression of NPR1 6 0.55 3.41 2.32
73 INT137977 Localization of P2RY2 5 0.80 3.07 2.27
74 INT115401 Negative_regulation of P2ry1 6 0.42 1.27 2.25
75 INT151816 Negative_regulation of P2ry2 3 0.02 3.1 2.23
76 INT120752 Positive_regulation of Gene_expression of NPPB 17 0.67 16.4 2.21
77 INT99844 Localization of P2ry1 7 0.74 4.05 2.19
78 INT215611 Negative_regulation of Positive_regulation of Adora1 6 0.43 1.18 2.16
79 INT39134 Positive_regulation of Ace2 3 0.14 0.57 2.13
80 INT25461 Negative_regulation of Regulation of Nppa 2 0.43 0.22 1.97
81 INT64075 Positive_regulation of Positive_regulation of Kcnma1 2 0.02 0.55 1.96
82 INT84264 Regulation of NPPB 22 0.61 21.18 1.94
83 INT26311 Negative_regulation of ACE2 8 0.59 16.35 1.94
84 INT33096 Negative_regulation of Gene_expression of ACE 9 0.43 2.84 1.93
85 INT103236 Positive_regulation of Positive_regulation of P2ry1 5 0.54 2.39 1.92
86 INT39133 Binding of Ace2 3 0.30 0.8 1.89
87 INT95467 Transcription of P2ry2 7 0.49 1.43 1.87
88 INT102288 Localization of P2ry2 4 0.55 1.02 1.83
89 INT124556 Negative_regulation of Positive_regulation of Adora1 3 0.51 1.2 1.81
90 INT102348 Regulation of P2ry2 6 0.40 2.18 1.79
91 INT182505 Positive_regulation of Gene_expression of AGTR1 12 0.65 13.18 1.77
92 INT22335 Regulation of Negative_regulation of ACE 10 0.44 7.01 1.77
93 INT168519 Positive_regulation of Gene_expression of Adora1 4 0.61 0.75 1.75
94 INT11098 Regulation of NPR1 5 0.37 1.39 1.74
95 INT111682 Transcription of P2ry1 4 0.52 1.26 1.71
96 INT29763 Negative_regulation of Adora1 3 0.42 0 1.64
97 INT105815 Positive_regulation of Gene_expression of P2RY2 9 0.50 3.62 1.52
98 INT182514 Binding of AGTR1 18 0.47 13.35 1.48
99 INT11057 Protein_catabolism of Nppa 11 0.94 3.34 1.47
100 INT150466 Regulation of Positive_regulation of P2ry2 1 0.37 1.26 1.42
101 INT241721 Positive_regulation of Transcription of Adora1 3 0.50 1.39 1.41
102 INT182511 Regulation of AGTR1 7 0.44 8.25 1.4
103 INT61636 Positive_regulation of Positive_regulation of P2ry2 4 0.34 0.13 1.4
104 INT61223 Positive_regulation of Negative_regulation of ACE 6 0.49 5.92 1.37
105 INT169232 Negative_regulation of Gene_expression of P2ry2 3 0.31 2.29 1.32
106 INT241737 Transcription of Adora1 3 0.72 0.89 1.32
107 INT117966 Binding of P2ry2 5 0.36 0.44 1.31
108 INT11099 Localization of NPR1 5 0.67 1.49 1.21
109 INT111681 Regulation of P2ry1 8 0.45 2.64 1.11
110 INT119974 Negative_regulation of P2RY2 3 0.43 1.6 1.04
111 INT281919 Localization of ACE2 4 0.75 2.69 1.02
112 INT129577 Negative_regulation of Positive_regulation of P2ry2 4 0.29 0.45 1
113 INT182516 Negative_regulation of Negative_regulation of ACE 9 0.42 6.84 0.99
114 INT72255 Binding of Kcnma1 4 0.02 0.2 0.99
115 INT107288 Positive_regulation of ACE2 4 0.66 5.48 0.99
116 INT216611 Regulation of Gene_expression of P2ry2 1 0.30 0.29 0.99
117 INT133846 Binding of NPPB 14 0.42 11.52 0.98
118 INT11100 Positive_regulation of Gene_expression of NPR1 2 0.37 1.49 0.98
119 INT182512 Positive_regulation of Positive_regulation of AGTR1 5 0.47 4.88 0.97
120 INT103235 Regulation of Localization of P2ry1 2 0.44 0.09 0.97
121 INT148117 Positive_regulation of Positive_regulation of P2RY2 2 0.24 0.96 0.94
122 INT233482 Positive_regulation of Gene_expression of P2ry2 4 0.43 0.76 0.92
123 INT23921 Negative_regulation of NPPB 13 0.58 16.19 0.9
124 INT29759 Negative_regulation of Negative_regulation of Nppa 3 0.58 1.5 0.9
125 INT11066 Negative_regulation of NPR1 5 0.27 0.89 0.88
126 INT215606 Positive_regulation of Localization of Adora1 3 0.49 0.44 0.87
127 INT95468 Transcription of P2ry1 4 0.60 0 0.86
128 INT7457 Localization of Kcnma1 3 0.60 2.75 0.85
129 INT139928 Negative_regulation of Kcnma1 6 0.37 1.19 0.84
130 INT167317 Negative_regulation of P2RY1 5 0.34 1.35 0.83
131 INT83995 Positive_regulation of Gene_expression of ACE 8 0.68 8.09 0.82
132 INT16587 Regulation of Negative_regulation of Nppa 3 0.53 0.84 0.82
133 INT151817 Positive_regulation of Transcription of P2ry2 2 0.21 1.19 0.82
134 INT32513 Regulation of Localization of NPR1 3 0.36 0.84 0.81
135 INT16537 Regulation of Positive_regulation of Nppa 2 0.45 1.44 0.76
136 INT69771 Positive_regulation of Kcnma1 6 0.52 0.31 0.74
137 INT5621 Positive_regulation of Transcription of Nppa 5 0.50 4.97 0.74
138 INT102894 Localization of AGTR1 5 0.73 1.75 0.74
139 INT342130 Negative_regulation of Localization of ACE2 1 0.01 1.16 0.74
140 INT148302 Regulation of Regulation of P2ry1 1 0.44 0.09 0.74
141 INT259902 Regulation of Gene_expression of ACE 3 0.45 1.87 0.7
142 INT111406 Binding of P2ry1 2 0.36 0.31 0.7
143 INT215809 Gene_expression of Kcnma1 11 0.58 0.53 0.66
144 INT48903 Protein_catabolism of ACE2 1 0.08 1.13 0.66
145 INT70530 Binding of NPR1 3 0.17 0.71 0.65
146 INT54183 Regulation of Positive_regulation of Adora1 1 0.17 0 0.65
147 INT288019 Regulation of Gene_expression of Kcnma1 3 0.00 0.7 0.63
148 INT216662 Regulation of Gene_expression of P2ry1 1 0.24 0.2 0.63
149 INT215607 Positive_regulation of Negative_regulation of Adora1 1 0.45 0 0.63
150 INT72446 Negative_regulation of Binding of ACE 4 0.42 2.48 0.62
151 INT56045 Positive_regulation of Localization of ACE 3 0.69 1.38 0.6
152 INT101705 Negative_regulation of Positive_regulation of Kcnma1 2 0.03 0 0.59
153 INT254132 Positive_regulation of Localization of NPPB 2 0.40 2.9 0.58
154 INT51718 Positive_regulation of Negative_regulation of Nppa 3 0.47 0.79 0.57
155 INT267971 Regulation of Localization of AGTR1 1 0.16 1.46 0.57
156 INT93647 Regulation of P2RY1 7 0.36 2.13 0.55
157 INT7293 Negative_regulation of Binding of Nppa 5 0.43 1.4 0.55
158 INT215572 Negative_regulation of Localization of P2ry1 1 0.15 0.08 0.55
159 INT243133 Positive_regulation of Positive_regulation of P2ry2 2 0.24 0.31 0.54
160 INT259774 Negative_regulation of Positive_regulation of P2ry1 1 0.33 1.11 0.54
161 INT307752 Negative_regulation of Regulation of Kcnma1 1 0.01 0.18 0.52
162 INT279525 Negative_regulation of Transcription of Adora1 1 0.43 0.26 0.51
163 INT233484 Positive_regulation of Gene_expression of P2ry1 4 0.43 0.95 0.5
164 INT249309 Regulation of Gene_expression of Adora1 6 0.39 0.51 0.49
165 INT308880 Positive_regulation of Negative_regulation of P2ry1 1 0.48 0.13 0.49
166 INT70532 Regulation of Regulation of NPR1 1 0.12 0.31 0.49
167 INT320019 Regulation of Positive_regulation of Kcnma1 1 0.01 0.05 0.49
168 INT215600 Regulation of Binding of Adora1 1 0.08 0.09 0.48
169 INT3907 Gene_expression of Ace2 5 0.54 2.35 0.46
170 INT5625 Regulation of Transcription of Nppa 2 0.26 0.29 0.46
171 INT180739 Binding of ACE2 5 0.37 7.88 0.45
172 INT107385 Regulation of Negative_regulation of AGTR1 2 0.15 1.26 0.42
173 INT166903 Negative_regulation of Gene_expression of NPPB 5 0.43 4.18 0.41
174 INT217010 Transcription of P2RY2 3 0.69 1.31 0.41
175 INT6563 Positive_regulation of Regulation of Nppa 1 0.33 0.44 0.41
176 INT182507 Negative_regulation of Gene_expression of AGTR1 1 0.40 1.13 0.4
177 INT330125 Transcription of AGTR1 1 0.52 1.29 0.39
178 INT32533 Negative_regulation of Gene_expression of Nppa 2 0.32 1.93 0.38
179 INT181635 Positive_regulation of Protein_catabolism of ACE 1 0.15 0.41 0.38
180 INT279524 Protein_catabolism of Adora1 1 0.88 0.34 0.38
181 INT279523 Positive_regulation of Protein_catabolism of Adora1 1 0.50 0.34 0.38
182 INT70531 Negative_regulation of Negative_regulation of NPR1 1 0.19 0.24 0.37
183 INT229626 Negative_regulation of Localization of ACE 3 0.41 2 0.36
184 INT185697 Positive_regulation of Positive_regulation of P2RY1 1 0.40 0.36 0.36
185 INT126559 Negative_regulation of Binding of P2RY2 1 0.06 0.21 0.36
186 INT106849 Phosphorylation of P2ry2 2 0.37 0.1 0.35
187 INT217014 Transcription of P2RY1 1 0.23 0.26 0.35
188 INT102889 Positive_regulation of Localization of AGTR1 3 0.38 0.43 0.34
189 INT102287 Binding of P2ry2 2 0.25 0 0.34
190 INT242293 Positive_regulation of Positive_regulation of NPPB 5 0.56 2.92 0.33
191 INT109852 Binding of P2RY1 3 0.35 1.04 0.33
192 INT141814 Regulation of Positive_regulation of P2ry1 1 0.44 0.15 0.33
193 INT32566 Positive_regulation of Localization of NPR1 1 0.58 0.17 0.33
194 INT99793 Regulation of Negative_regulation of Kcnma1 1 0.01 0.1 0.3
195 INT96863 Transcription of ACE 3 0.69 0.38 0.29
196 INT230864 Regulation of Binding of ACE 1 0.22 0.79 0.29
197 INT288846 Negative_regulation of Transcription of ACE 1 0.43 0 0.29
198 INT95464 Regulation of Transcription of P2ry1 1 0.25 0 0.28
199 INT17158 Regulation of Protein_catabolism of Nppa 1 0.24 0.1 0.28
200 INT90784 Positive_regulation of Gene_expression of Ace2 3 0.40 1.34 0.27
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