GO:0042326

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Name negative regulation of phosphorylation
Categary Process
Go Slim No
Go Link GO:0042326
Unique Molecular Interactions 500
Total Molecular Interactions 645
Total Single Events 6983
Pain Genes Associated 43

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
2 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
3 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
4 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
5 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
6 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
7 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
8 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
9 INT169346 Nxn Negative_regulation of Dynll1 1 0.06 1.22 1.87
10 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
11 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
12 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
13 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
14 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
15 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
16 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
17 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
18 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
19 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
20 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
21 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
22 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
23 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
24 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
25 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
26 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
27 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
28 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
29 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
30 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
31 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
32 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
33 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
34 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
35 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
36 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
37 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
38 INT48341 Negative_regulation of Pde8a Regulation of Ahsg 1 0.22 0 0.9
39 INT48342 Pde8a Regulation of Ahsg 1 0.24 0 0.9
40 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
41 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
42 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
43 INT307045 Tmie Negative_regulation of Positive_regulation of Casp3 1 0.01 0.29 0.85
44 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
45 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
46 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
47 INT307044 Tmie Regulation of Casp3 1 0.01 0 0.75
48 INT114860 Negative_regulation of Insrr Positive_regulation of Casp3 1 0.02 0.71 0.73
49 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
50 INT151559 Atp2a1 Negative_regulation of Positive_regulation of CASP3 1 0.06 0.68 0.66
51 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
52 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
53 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
54 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
55 INT11558 POMC Positive_regulation of CASP3 1 0.05 0 0.62
56 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
57 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
58 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
59 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61
60 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
61 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61
62 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
63 INT114505 Negative_regulation of Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
64 INT114506 Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
65 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
66 INT163376 RYBP Positive_regulation of Gene_expression of Casp3 2 0.01 0.57 0.59
67 INT112399 Olr897-ps Regulation of Gene_expression of Casp3 1 0.03 0 0.54
68 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
69 INT74517 Binding of Casp3 and Cnrip1 1 0.31 0 0.51
70 INT234609 Binding of CASP3 and IMMT 1 0.00 0.5 0.5
71 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
72 INT307048 Cnr1 Positive_regulation of Casp3 1 0.08 0 0.47
73 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
74 INT20761 INHBA Regulation of Localization of GNRH1 1 0.02 0 0.46
75 INT319554 Sgk1 Regulation of Cdkn1a 1 0.26 0.09 0.45
76 INT349853 Binding of Hspb1 and Jun 1 0.14 2.3 0.45
77 INT57236 Casp3 Positive_regulation of Prl 1 0.09 0 0.41
78 INT158032 Binding of CDKN2A and KRT20 1 0.28 0.59 0.4
79 INT57235 Casp3 Positive_regulation of Localization of Prl 1 0.15 0 0.4
80 INT52960 Casp3 Negative_regulation of Positive_regulation of Ltp 1 0.02 0 0.37
81 INT145908 Pdyn Regulation of Positive_regulation of Casp3 1 0.14 0.94 0.37
82 INT285570 Binding of IL8 and Cdkn1c 1 0.11 0.76 0.34
83 INT204071 HP Positive_regulation of Gene_expression of CDKN2A 1 0.00 3.48 0.34
84 INT130803 MC1R Regulation of Positive_regulation of Cdkn2a 1 0.17 0.82 0.34
85 INT119262 PPM1E Negative_regulation of Positive_regulation of CDKN1A 1 0.01 0.96 0.33
86 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
87 INT166391 IFI27 Regulation of Gene_expression of CDKN1B 1 0.33 0.41 0.31
88 INT286708 Negative_regulation of Mapk1 Negative_regulation of Casp3 1 0.12 0 0.31
89 INT220521 Ugt1a6b Positive_regulation of Cdkn1b 1 0.01 2.38 0.31
90 INT166397 CDKN1B Regulation of Gene_expression of IFI27 1 0.33 0.41 0.31
91 INT166162 Ccr9 Negative_regulation of Positive_regulation of Casp3 1 0.18 1.49 0.28
92 INT172977 Cdkn1a Negative_regulation of Positive_regulation of Inca1 1 0.00 1.39 0.27
93 INT237380 Binding of Cdkn2d and Il12b 1 0.01 0.45 0.26
94 INT148629 Binding of Cat and Casp3 1 0.08 0.09 0.26
95 INT147593 Binding of CDK4 and CDKN2A 1 0.42 0.23 0.26
96 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
97 INT147592 Positive_regulation of Binding of CDK4 and CDKN2A 1 0.44 0.23 0.26
98 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
99 INT121249 Binding of ANXA5 and CASP3 1 0.36 0.67 0.25
100 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
101 INT149713 Binding of Casp3 and Fas 1 0.40 1.09 0.25
102 INT171049 Binding of FAS and Positive_regulation of Gene_expression of CASP3 1 0.04 1.41 0.24
103 INT210785 Cdkn1c Positive_regulation of Itgbl1 1 0.38 0 0.23
104 INT245555 Runx1 Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
105 INT245565 Runx1 Negative_regulation of Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
106 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22
107 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22
108 INT349344 Bdnf Negative_regulation of Casp3 1 0.13 0.96 0.22
109 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22
110 INT181675 Positive_regulation of Casp9 Positive_regulation of Casp3 1 0.06 0.51 0.2
111 INT315384 Adcyap1 Negative_regulation of Positive_regulation of Casp3 1 0.02 0.53 0.2
112 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
113 INT322543 Binding of FOXO3 and Cdkn1b 1 0.08 0.84 0.19
114 INT181677 Casp9 Positive_regulation of Casp3 1 0.06 0.5 0.19
115 INT261387 Nsdhl Negative_regulation of Casp3 1 0.03 1.08 0.19
116 INT212084 NOXO1 Positive_regulation of CDKN1A 1 0.06 0.53 0.19
117 INT349855 Atf3 Regulation of Hspb1 1 0.37 0.77 0.19
118 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
119 INT351442 Gria2 Regulation of Gene_expression of Casp3 1 0.01 0 0.18
120 INT275400 Casp3 Positive_regulation of NDRG1 1 0.00 1.36 0.18
121 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
122 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
123 INT275461 Binding of Atxn1 and Atxn2 1 0.39 1.1 0.17
124 INT96416 CYC1 Positive_regulation of Casp3 1 0.02 0.96 0.17
125 INT119263 Binding of CDKN1A and PPM1E 1 0.01 0.46 0.17
126 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
127 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
128 INT136855 Arf5 Positive_regulation of Cdkn2a 1 0.07 1.8 0.15
129 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15
130 INT128705 Binding of Adrb2 and Ahsg 1 0.00 0.23 0.15
131 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14
132 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
133 INT123192 Bmp6 Positive_regulation of CDKN1A 1 0.18 0.61 0.14
134 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14
135 INT213551 Proc Regulation of Bmp7 1 0.00 0.15 0.14
136 INT226205 Negative_regulation of Akt1 Positive_regulation of Casp3 1 0.04 0.71 0.14
137 INT88410 BMP7 Negative_regulation of CDK2 1 0.35 0 0.14
138 INT314867 Binding of Cdc7 and Cdkn2b 1 0.25 1.16 0.14
139 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
140 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14
141 INT193789 SDF2L1 Positive_regulation of CDKN1A 1 0.00 0.68 0.13
142 INT275397 Binding of ITIH4 and Casp3 1 0.02 0.64 0.13
143 INT193785 SDF2L1 Positive_regulation of Gene_expression of CDKN1A 1 0.00 0.68 0.13
144 INT86429 Binding of Hspb1 and Esr1 1 0.19 0.26 0.13
145 INT252631 Binding of Casp3 and Tnfrsf1a 1 0.10 0.69 0.13
146 INT275389 Binding of Casp3 and Htatsf1 1 0.00 0.64 0.13
147 INT252632 Binding of Casp3 and Tradd 1 0.11 0.68 0.12
148 INT349345 Bdnf Negative_regulation of Positive_regulation of Casp3 1 0.13 1.02 0.12
149 INT201754 CASP8 Positive_regulation of Casp3 1 0.00 0.47 0.12
150 INT315391 IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
151 INT315390 Positive_regulation of IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
152 INT142961 Binding of Nfkb1 and Casp3 1 0.00 1.02 0.11
153 INT234062 Nes Positive_regulation of Casp3 1 0.18 0.08 0.11
154 INT15902 PKIA Negative_regulation of Positive_regulation of Prkaca 1 0.10 0 0.1
155 INT285023 Casp3 Negative_regulation of Casp7 1 0.07 0.44 0.1
156 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
157 INT233858 CHKA Positive_regulation of Gene_expression of CDKN1B 1 0.10 0.17 0.09
158 INT289539 Negative_regulation of Sirt1 Negative_regulation of Gene_expression of Agrp 1 0.29 0.47 0.09
159 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
160 INT129624 Bmp7 Positive_regulation of Gene_expression of Id2 1 0.26 0.31 0.08
161 INT129623 Bmp7 Positive_regulation of Gene_expression of Id3 1 0.37 0.31 0.08
162 INT237922 TNFSF10 Positive_regulation of CDKN1A 1 0.09 3.28 0.08
163 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08
164 INT129625 Id2 Positive_regulation of Gene_expression of Bmp7 1 0.24 0.31 0.08
165 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
166 INT129622 Id3 Positive_regulation of Gene_expression of Bmp7 1 0.25 0.31 0.08
167 INT210790 Ihh Negative_regulation of Cdkn1c 1 0.30 0 0.08
168 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08
169 INT136856 Cdkn2a Positive_regulation of Arf5 1 0.01 0.9 0.08
170 INT289603 Sirt1 Negative_regulation of Localization of PPARG 1 0.02 0.43 0.08
171 INT208555 YWHAQ Positive_regulation of Atxn1 1 0.77 1.02 0.08
172 INT110855 Pkia Negative_regulation of Egf 1 0.15 1.2 0.08
173 INT302139 LAMTOR1 Regulation of CDKN2A 1 0.08 0.26 0.08
174 INT302157 MRPL28 Regulation of CDKN2A 1 0.09 0.26 0.08
175 INT245118 RBM45 Negative_regulation of CDKN2B 1 0.01 1.41 0.08
176 INT220514 Ppara Positive_regulation of Gene_expression of Cdkn1b 1 0.08 1 0.08
177 INT302148 IFI27 Regulation of CDKN2A 1 0.11 0.26 0.08
178 INT245119 Negative_regulation of RBM45 Negative_regulation of CDKN2B 1 0.01 1.43 0.08
179 INT289540 Sirt1 Negative_regulation of Localization of Ins1 1 0.03 0.43 0.08
180 INT129627 Bmp7 Positive_regulation of Id2 1 0.24 0.25 0.07
181 INT289533 Sirt1 Negative_regulation of Pparg 1 0.18 0.42 0.07
182 INT256160 Positive_regulation of Binding of Pgc and Sirt1 1 0.55 0.21 0.07
183 INT289602 Sirt1 Negative_regulation of PPARG 1 0.02 0.37 0.07
184 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07
185 INT256161 Binding of Pgc and Sirt1 1 0.38 0.21 0.07
186 INT128706 Binding of MET and Ahsg 1 0.28 0.34 0.07
187 INT129626 Bmp7 Positive_regulation of Id3 1 0.25 0.25 0.07
188 INT193783 ITIH4 Regulation of Gene_expression of CDKN1A 1 0.03 0.55 0.07
189 INT119268 CDKN1A Regulation of CREBBP 1 0.21 0.44 0.07
190 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
191 INT203849 Ass1 Positive_regulation of Casp3 1 0.00 0.71 0.07
192 INT302160 LAMTOR1 Regulation of CDKN1A 1 0.08 0.26 0.06
193 INT302150 MRPL28 Regulation of CDKN1B 1 0.09 0.26 0.06
194 INT175966 Kctd1 Negative_regulation of Positive_regulation of CASP3 1 0.09 0.82 0.06
195 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
196 INT201973 Bmp7 Positive_regulation of ap 1 0.00 0.18 0.06
197 INT302129 BAX Regulation of Positive_regulation of CASP3 1 0.02 0.69 0.06
198 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
199 INT302136 LAMTOR1 Regulation of CDKN1B 1 0.08 0.26 0.06
200 INT302127 MRPL28 Regulation of CDKN1A 1 0.09 0.26 0.06

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of phosphorylation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of phosphorylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
2 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
3 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
4 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
5 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
6 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
7 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
8 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38
9 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
10 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
11 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
12 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
13 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
14 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
15 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
16 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
17 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2
18 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
19 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
20 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99
21 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61
22 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
23 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
24 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
25 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
26 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
27 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
28 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
29 INT98178 Localization of Casp3 32 0.65 21.01 7.77
30 INT57176 Positive_regulation of Dynll1 9 0.49 4.76 7.71
31 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47
32 INT73181 Gene_expression of Hspb1 24 0.78 15.84 7.31
33 INT74099 Negative_regulation of Dynll1 8 0.56 3.43 7.25
34 INT102814 Negative_regulation of CASP3 46 0.43 28.54 6.94
35 INT102749 Positive_regulation of Positive_regulation of CASP3 32 0.67 26.07 6.93
36 INT71496 Positive_regulation of Hspb1 15 0.69 14.7 6.86
37 INT108585 Positive_regulation of Gene_expression of CASP3 35 0.70 28.37 6.45
38 INT57232 Binding of Casp3 22 0.36 9.42 6.2
39 INT134544 Negative_regulation of Positive_regulation of CASP3 23 0.57 18.48 5.95
40 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
41 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69
42 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56
43 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
44 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
45 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38
46 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
47 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
48 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
49 INT74393 Gene_expression of Dynll1 8 0.65 2.64 4.39
50 INT88805 Protein_catabolism of CASP3 24 0.86 18.38 3.7
51 INT97126 Regulation of CASP3 9 0.40 8.15 3.6
52 INT169344 Positive_regulation of Gene_expression of Dynll1 3 0.49 2.34 3.48
53 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44
54 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
55 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
56 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28
57 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26
58 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
59 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
60 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
61 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
62 INT27260 Gene_expression of DYNLL1 8 0.75 7.72 2.78
63 INT24068 Localization of Hspb1 6 0.78 6.11 2.75
64 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74
65 INT22739 Positive_regulation of DYNLL1 5 0.67 1.69 2.67
66 INT99548 Positive_regulation of Gene_expression of CDKN1B 12 0.67 6.79 2.5
67 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48
68 INT131112 Phosphorylation of Casp3 7 0.63 4.1 2.46
69 INT338170 Regulation of Regulation of CDKN2A 1 0.44 0.96 2.46
70 INT31118 Localization of Casp3 17 0.73 11.55 2.3
71 INT86426 Gene_expression of Hspb1 16 0.78 10.86 2.26
72 INT111038 Gene_expression of Cdkn1b 23 0.75 25.35 2.22
73 INT86999 Regulation of DYNLL1 5 0.44 2.85 2.18
74 INT108589 Negative_regulation of Gene_expression of CASP3 13 0.57 10.52 2.14
75 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12
76 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
77 INT22738 Negative_regulation of DYNLL1 17 0.57 6.68 2.06
78 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04
79 INT26415 Regulation of Phosphorylation of PKIA 1 0.01 0.06 2.04
80 INT26417 Phosphorylation of PKIA 1 0.02 0.06 2.04
81 INT79198 Positive_regulation of Positive_regulation of Dynll1 2 0.42 0.99 1.99
82 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96
83 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9
84 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
85 INT102532 Protein_catabolism of Casp3 24 0.64 16.78 1.64
86 INT104331 Negative_regulation of Gene_expression of CDKN1A 24 0.57 13.68 1.63
87 INT167288 Regulation of Dynll1 3 0.45 1.22 1.56
88 INT137505 Positive_regulation of Cdkn1b 18 0.67 10.55 1.54
89 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
90 INT106749 Negative_regulation of Negative_regulation of Casp3 6 0.34 5.12 1.48
91 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
92 INT54996 Regulation of KAT2B 1 0.19 0.38 1.45
93 INT140843 Regulation of Phosphorylation of Casp3 1 0.25 0.37 1.44
94 INT181809 Gene_expression of Atxn1 81 0.77 28.66 1.42
95 INT159186 Positive_regulation of Gene_expression of DYNLL1 1 0.49 1.25 1.4
96 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
97 INT78470 Negative_regulation of Gene_expression of CDKN2A 14 0.59 14.44 1.38
98 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38
99 INT171690 Transcription of Casp3 8 0.55 2.62 1.36
100 INT97943 Positive_regulation of Protein_catabolism of Casp3 7 0.28 7.4 1.35
101 INT24069 Negative_regulation of Localization of Hspb1 3 0.14 3.93 1.3
102 INT160009 Transcription of CDKN1B 2 0.67 1.43 1.29
103 INT114220 Negative_regulation of Gene_expression of Cdkn1b 4 0.33 4.11 1.23
104 INT20764 Localization of INHBA 3 0.71 0.94 1.22
105 INT93625 Gene_expression of Cdkn1c 2 0.75 0.42 1.2
106 INT76303 Negative_regulation of Positive_regulation of Hspb1 1 0.42 0.49 1.17
107 INT48338 Gene_expression of Ahsg 2 0.52 0.25 1.16
108 INT20762 Negative_regulation of Localization of INHBA 1 0.03 0 1.15
109 INT160008 Positive_regulation of Transcription of CDKN1B 1 0.49 0.98 1.1
110 INT111036 Positive_regulation of Cdkn1b 16 0.45 9 1.06
111 INT102845 Localization of CASP3 7 0.81 2.81 1.06
112 INT111037 Positive_regulation of Gene_expression of Cdkn1b 5 0.39 11.17 1.06
113 INT42104 Regulation of Cdkn2a 4 0.44 5.67 1.06
114 INT71498 Binding of Hspb1 7 0.42 7.38 1.05
115 INT71499 Localization of Hspb1 4 0.72 1.38 1.05
116 INT123962 Phosphorylation of Hspb1 8 0.82 2.08 1.04
117 INT160012 Regulation of Gene_expression of CDKN1B 2 0.44 1.17 1.04
118 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
119 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
120 INT75251 Negative_regulation of Positive_regulation of DYNLL1 1 0.41 0.18 0.99
121 INT125892 Regulation of Hspb1 2 0.48 4.28 0.98
122 INT20763 Positive_regulation of Localization of INHBA 1 0.03 0 0.96
123 INT24067 Negative_regulation of Hspb1 1 0.11 0.67 0.95
124 INT338168 Positive_regulation of Binding of CDKN2A 1 0.49 0.52 0.94
125 INT31117 Binding of Casp3 14 0.23 5.27 0.93
126 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
127 INT33495 Regulation of Ahsg 1 0.23 0 0.86
128 INT48339 Regulation of Localization of Ahsg 1 0.21 0 0.86
129 INT48337 Localization of Ahsg 1 0.54 0 0.85
130 INT131105 Positive_regulation of Negative_regulation of Casp3 3 0.29 3.15 0.84
131 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
132 INT220498 Negative_regulation of Gene_expression of Cdkn1b 9 0.21 7.48 0.8
133 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
134 INT146521 Negative_regulation of Positive_regulation of CDKN1A 6 0.42 3.29 0.79
135 INT144429 Positive_regulation of Cdkn2a 7 0.58 4.05 0.78
136 INT20765 Negative_regulation of INHBA 6 0.34 1.91 0.77
137 INT181667 Regulation of Regulation of Casp3 1 0.22 1.7 0.77
138 INT93621 Positive_regulation of Gene_expression of Cdkn1c 1 0.67 0.42 0.77
139 INT129115 Negative_regulation of Cdkn2a 16 0.50 17.03 0.76
140 INT141150 Localization of BMP7 4 0.56 2.84 0.76
141 INT109983 Positive_regulation of Hspb1 7 0.66 6.66 0.72
142 INT129490 Negative_regulation of Protein_catabolism of Casp3 4 0.22 3.91 0.71
143 INT125890 Negative_regulation of Regulation of Hspb1 2 0.42 1.39 0.69
144 INT224579 Gene_expression of Cdkn2d 6 0.41 4.23 0.68
145 INT351454 Regulation of Transcription of Casp3 1 0.02 0.51 0.67
146 INT234928 Phosphorylation of Hspb1 3 0.72 17.04 0.65
147 INT70216 Gene_expression of HSPB1 8 0.78 4.81 0.64
148 INT131976 Positive_regulation of Protein_catabolism of CASP3 4 0.49 3.76 0.64
149 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
150 INT126732 Regulation of Cdkn1a 6 0.39 2.13 0.63
151 INT89363 Positive_regulation of Ahsg 2 0.11 1.11 0.63
152 INT251026 Negative_regulation of Phosphorylation of CDKN2A 5 0.42 5.02 0.62
153 INT177886 Positive_regulation of Gene_expression of Cdkn2a 3 0.67 3.42 0.62
154 INT241621 Regulation of Cdkn1b 2 0.06 0.36 0.62
155 INT100294 Positive_regulation of Gene_expression of Bmp7 8 0.46 5.41 0.61
156 INT113850 Negative_regulation of Cdkn1b 4 0.42 3.45 0.6
157 INT147598 Negative_regulation of Positive_regulation of CDKN2A 3 0.41 1.47 0.59
158 INT89126 Regulation of BMP7 7 0.45 2.5 0.58
159 INT242061 Positive_regulation of Negative_regulation of Casp3 3 0.09 1.7 0.58
160 INT98786 Positive_regulation of Gene_expression of Cdkn1b 21 0.67 8.7 0.56
161 INT181673 Negative_regulation of Transcription of Casp3 3 0.34 0.61 0.55
162 INT120358 Positive_regulation of Positive_regulation of CDKN1B 2 0.49 1.26 0.55
163 INT242011 Localization of Cdkn2a 4 0.73 2.49 0.54
164 INT144701 Gene_expression of Cdkn2a 15 0.75 8.42 0.53
165 INT165537 Negative_regulation of Bmp7 2 0.43 0.55 0.52
166 INT123963 Positive_regulation of Gene_expression of Hspb1 7 0.70 3.39 0.51
167 INT159214 Positive_regulation of Gene_expression of BMP7 6 0.46 2.16 0.51
168 INT100191 Gene_expression of Cdkn2b 1 0.65 0.06 0.51
169 INT144431 Positive_regulation of Transcription of Cdkn2a 1 0.41 1.11 0.51
170 INT144426 Transcription of Cdkn2a 1 0.42 1.11 0.51
171 INT289580 Negative_regulation of Sirt1 23 0.58 9.03 0.48
172 INT163828 Localization of Cdkn1b 4 0.66 5.2 0.48
173 INT20766 Positive_regulation of INHBA 4 0.66 5.66 0.48
174 INT129620 Regulation of Gene_expression of Bmp7 3 0.42 3.2 0.47
175 INT137504 Positive_regulation of Positive_regulation of Cdkn1b 2 0.45 1.71 0.45
176 INT163829 Positive_regulation of Localization of Cdkn1b 2 0.17 0.96 0.45
177 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
178 INT300291 Phosphorylation of Sirt1 1 0.77 6.07 0.45
179 INT220088 Positive_regulation of Positive_regulation of CDKN2A 4 0.49 4.04 0.44
180 INT129144 Regulation of Localization of Casp3 1 0.26 0.84 0.44
181 INT153436 Positive_regulation of Localization of Casp3 3 0.49 2.12 0.43
182 INT97606 Negative_regulation of Cdkn1a 7 0.43 4.24 0.42
183 INT132496 Regulation of Gene_expression of CASP3 6 0.20 4.59 0.42
184 INT240935 Transcription of Sirt1 2 0.68 0.42 0.42
185 INT252657 Positive_regulation of Phosphorylation of CDKN2A 2 0.45 3.09 0.42
186 INT123960 Negative_regulation of Phosphorylation of Hspb1 2 0.43 0.48 0.42
187 INT42105 Regulation of Positive_regulation of Cdkn2a 1 0.44 0.33 0.42
188 INT340290 Regulation of Transcription of Sirt1 1 0.43 0.13 0.42
189 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
190 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
191 INT125592 Negative_regulation of Negative_regulation of CDKN1A 2 0.42 2.07 0.41
192 INT109486 Positive_regulation of Negative_regulation of Dynll1 1 0.48 0 0.41
193 INT118460 Binding of Bmp7 3 0.46 1.3 0.4
194 INT117440 Positive_regulation of Cdkn1a 3 0.67 2.95 0.4
195 INT155293 Positive_regulation of Protein_catabolism of Casp3 3 0.45 1.7 0.4
196 INT131018 Phosphorylation of Cdkn1a 3 0.61 2.06 0.4
197 INT123964 Transcription of Hspb1 2 0.53 0.67 0.37
198 INT225223 Localization of Cdkn2b 2 0.62 1.29 0.37
199 INT239084 Localization of KAT2B 4 0.73 3.08 0.36
200 INT89367 Negative_regulation of Ahsg 2 0.14 0.85 0.36
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