GO:0042346

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Name positive regulation of NF-kappaB import into nucleus
Categary Process
Go Slim No
Go Link GO:0042346
Unique Molecular Interactions 2464
Total Molecular Interactions 3525
Total Single Events 28818
Pain Genes Associated 37

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of NF-kappaB import into nucleus. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of NF-kappaB import into nucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
5 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
6 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
7 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
8 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
9 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
10 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
11 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
12 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
13 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
14 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
15 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
16 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
17 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
18 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
19 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
20 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
21 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
22 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
23 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
24 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
25 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
26 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
27 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
28 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
29 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
30 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
31 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
32 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
33 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
34 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
35 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
36 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
37 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
38 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
39 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
40 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
41 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
42 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
43 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
44 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
45 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
46 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
47 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
48 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
49 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
50 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
51 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
52 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
53 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
54 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
55 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
56 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
57 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
58 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
59 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
60 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
61 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
62 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
63 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
64 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
65 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
66 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
67 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
68 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
69 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
70 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
71 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
72 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
73 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
74 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
75 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
76 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
77 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
78 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
79 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
80 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
81 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
82 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
83 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
84 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
85 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
86 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
87 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
88 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
89 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
90 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
91 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
92 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
93 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
94 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
95 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
96 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
97 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
98 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
99 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
100 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
101 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
102 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
103 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
104 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
105 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
106 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
107 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
108 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
109 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
110 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
111 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
112 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
113 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
114 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
115 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
116 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
117 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
118 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
119 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
120 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
121 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
122 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
123 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
124 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
125 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
126 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
127 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11
128 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
129 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
130 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
131 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
132 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
133 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
134 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
135 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
136 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
137 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
138 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
139 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
140 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
141 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
142 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
143 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
144 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
145 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
146 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
147 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
148 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
149 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07
150 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
151 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
152 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
153 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
154 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04
155 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
156 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
157 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
158 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
159 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
160 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
161 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
162 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
163 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
164 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
165 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
166 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
167 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
168 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
169 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
170 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
171 INT69307 Prkcq Negative_regulation of TH1L 1 0.00 0.98 0.98
172 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
173 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
174 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
175 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
176 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
177 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
178 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
179 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
180 INT240123 MIR885 Negative_regulation of IL1B 1 0.01 1.57 0.96
181 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
182 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
183 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
184 INT130722 Binding of IL1B and Nfkb1 1 0.28 1.23 0.95
185 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
186 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
187 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
188 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
189 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
190 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
191 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
192 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
193 INT81919 Binding of HSF1 and IL1B 1 0.42 0.77 0.93
194 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
195 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
196 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
197 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
198 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
199 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
200 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of NF-kappaB import into nucleus. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of NF-kappaB import into nucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
7 INT6481 Binding of TNF 624 0.48 510.2 214.82
8 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
9 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
10 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
11 INT9660 Regulation of TNF 363 0.62 312.94 139.99
12 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
13 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
14 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
15 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
16 INT10166 Localization of Tnf 237 0.81 153.95 88.64
17 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
18 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
19 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
20 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
21 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
22 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
23 INT6849 Localization of IL1B 229 0.81 112.56 69.63
24 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
25 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
26 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
27 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
28 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
29 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
30 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
31 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
32 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
33 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
34 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
35 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
36 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
37 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
38 INT13354 Transcription of TNF 108 0.72 85.81 42.32
39 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
40 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
41 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
42 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17
43 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
44 INT6484 Binding of IL1B 122 0.47 75.84 35.07
45 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
46 INT35406 Localization of Tnf 94 0.81 64.63 31.65
47 INT9347 Localization of Il1b 58 0.81 26.13 31.53
48 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
49 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
50 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
51 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
52 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
53 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
54 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
55 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
56 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
57 INT134651 Binding of TLR4 89 0.48 66.96 23.19
58 INT48081 Localization of Il1b 46 0.80 21.59 22.4
59 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
60 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
61 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
62 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
63 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
64 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
65 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
66 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
67 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
68 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
69 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
70 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67
71 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
72 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
73 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
74 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
75 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
76 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
77 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
78 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
79 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
80 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44
81 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
82 INT10173 Binding of Tnf 45 0.48 35.6 14.32
83 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
84 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
85 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
86 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
87 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
88 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
89 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
90 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
91 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
92 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86
93 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39
94 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
95 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
96 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65
97 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
98 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
99 INT150540 Binding of TLR2 50 0.45 35.86 10.43
100 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
101 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39
102 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
103 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
104 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
105 INT226463 Positive_regulation of IL23A 23 0.45 21.58 9.18
106 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05
107 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
108 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
109 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
110 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
111 INT66926 Transcription of Il1b 15 0.69 13.16 7.81
112 INT48077 Positive_regulation of Localization of Il1b 17 0.69 8.8 7.68
113 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
114 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
115 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
116 INT68299 Binding of Tnf 17 0.39 12.55 7.49
117 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
118 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
119 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
120 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
121 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84
122 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
123 INT4431 Negative_regulation of Eda 10 0.46 3.53 6.81
124 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67
125 INT207892 Binding of Tlr9 35 0.46 26.66 6.61
126 INT48076 Negative_regulation of Localization of Il1b 10 0.59 3.46 6.58
127 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44
128 INT67130 Negative_regulation of Localization of Il1b 7 0.57 1.36 6.42
129 INT137206 Positive_regulation of TLR2 47 0.65 33.36 6.4
130 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
131 INT84716 Negative_regulation of Positive_regulation of Il1b 9 0.57 5.34 6.27
132 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
133 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
134 INT97797 Localization of TLR4 18 0.77 13.78 6
135 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
136 INT80750 Binding of Il1b 11 0.47 7.97 5.95
137 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
138 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86
139 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71
140 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
141 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
142 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55
143 INT10705 Binding of Il1b 9 0.36 2.8 5.53
144 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
145 INT51411 Negative_regulation of EDAR 8 0.41 1.05 5.49
146 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
147 INT142595 Negative_regulation of Tlr2 24 0.52 19.17 5.43
148 INT50197 Positive_regulation of Transcription of Il1b 11 0.50 8.95 5.41
149 INT174688 Binding of Tlr2 45 0.42 36.65 5.25
150 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
151 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18
152 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
153 INT175312 Positive_regulation of Gene_expression of IL23A 17 0.45 14.8 5.05
154 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
155 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
156 INT185398 Negative_regulation of Gene_expression of TLR2 34 0.55 27.21 4.73
157 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
158 INT16047 Negative_regulation of Positive_regulation of Il1b 11 0.57 5.27 4.66
159 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54
160 INT188672 Positive_regulation of Tlr9 15 0.67 13.1 4.48
161 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33
162 INT56404 Gene_expression of EDA 16 0.75 7.09 4.24
163 INT48080 Positive_regulation of Positive_regulation of Il1b 5 0.50 4.3 4.19
164 INT149986 Positive_regulation of Gene_expression of Tlr9 5 0.67 8.18 4.15
165 INT19190 Regulation of Localization of IL1B 14 0.50 8.71 4.12
166 INT181414 Gene_expression of Ccl19 12 0.74 9.8 4.11
167 INT158595 Gene_expression of Tlr3 25 0.69 12.09 4.07
168 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99
169 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
170 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89
171 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
172 INT115773 Negative_regulation of Localization of Ptgs2 6 0.43 2.99 3.81
173 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
174 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77
175 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
176 INT158596 Binding of Tlr3 24 0.47 11.66 3.69
177 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63
178 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
179 INT53200 Binding of Ptgs2 11 0.48 5.08 3.54
180 INT264970 Positive_regulation of Localization of TLR2 1 0.11 4.21 3.37
181 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
182 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
183 INT250884 Binding of IL23A 5 0.19 7.17 3.17
184 INT66922 Positive_regulation of Transcription of Il1b 7 0.49 6.58 3.14
185 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11
186 INT186805 Transcription of TLR2 12 0.63 9.66 3.04
187 INT128179 Gene_expression of RHOA 7 0.64 2.48 3.01
188 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
189 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
190 INT260424 Negative_regulation of Tlr9 8 0.41 8.19 2.92
191 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
192 INT6479 Negative_regulation of Binding of IL1B 10 0.43 5.1 2.78
193 INT112147 Positive_regulation of Negative_regulation of Il1b 3 0.49 3.42 2.77
194 INT204524 Binding of TLR9 17 0.43 11.69 2.76
195 INT5460 Positive_regulation of EDAR 10 0.23 8.18 2.71
196 INT10350 Negative_regulation of Regulation of Il1b 3 0.41 0.58 2.69
197 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
198 INT11379 Positive_regulation of Negative_regulation of IL1B 9 0.49 7.2 2.64
199 INT133029 Regulation of TLR2 18 0.56 11.31 2.62
200 INT138437 Gene_expression of Sphk1 23 0.65 10.01 2.61
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