GO:0042379

From wiki-pain
Jump to: navigation, search
Name chemokine receptor binding
Categary Function
Go Slim No
Go Link GO:0042379
Unique Molecular Interactions 91
Total Molecular Interactions 189
Total Single Events 1113
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chemokine receptor binding. They are ordered first by their pain relevance and then by number of times they were reported for chemokine receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
2 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
3 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
4 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
5 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
6 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
7 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
8 INT247759 Binding of Ccrl2 and Rarres2 1 0.26 1.19 0.9
9 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
10 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
11 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
12 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
13 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
14 INT12052 Xcl1 Negative_regulation of Rnpep 1 0.01 0 0.71
15 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67
16 INT245299 Ccl5 Positive_regulation of Localization of IL8 1 0.11 2.87 0.66
17 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
18 INT254637 Bdkrb2 Regulation of Gene_expression of Ccl5 1 0.17 1.22 0.56
19 INT171278 TNFSF12 Positive_regulation of CCL5 1 0.02 0.93 0.48
20 INT181444 Ccl5 Positive_regulation of Csf2 1 0.07 1.88 0.45
21 INT186758 Il13 Regulation of Ccl5 2 0.17 0.17 0.39
22 INT316830 TNF Regulation of CCL5 1 0.02 1.02 0.39
23 INT189491 Icam1 Positive_regulation of Transcription of Ccl5 1 0.19 0.64 0.36
24 INT181432 Csf2 Positive_regulation of Ccl5 1 0.03 0.81 0.29
25 INT247758 Ccrl2 Positive_regulation of Rarres2 1 0.25 0.87 0.27
26 INT246435 Xcl1 Positive_regulation of Gene_expression of Cd79a 1 0.07 0.83 0.27
27 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 0.32 0.31 0.27
28 INT237088 Binding of Cxcl9 and Ccl5 1 0.29 1.51 0.26
29 INT246438 Ccl5 Positive_regulation of Gene_expression of Cd79a 1 0.13 0.83 0.26
30 INT266802 Dlst Positive_regulation of CCL5 1 0.00 0.95 0.25
31 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25
32 INT80286 IFNG Positive_regulation of Gene_expression of CCL5 1 0.24 0.37 0.23
33 INT80287 IL4 Positive_regulation of Gene_expression of CCL5 1 0.21 0.37 0.23
34 INT318174 Binding of Crp and Xcl1 1 0.03 1.9 0.22
35 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21
36 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 0.01 0.82 0.21
37 INT170995 Binding of IFNA1 and Positive_regulation of Localization of CCL5 1 0.03 0.34 0.19
38 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
39 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
40 INT226344 Gene_expression of IL9 Positive_regulation of CCL5 1 0.07 1.03 0.18
41 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
42 INT246437 Ccl5 Positive_regulation of Regulation of Hand1 1 0.19 0.76 0.17
43 INT247755 Binding of Cmklr1 and Ccrl2 1 0.05 0.53 0.17
44 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17
45 INT246440 Ccl5 Positive_regulation of Positive_regulation of Xcl1 1 0.27 1.28 0.16
46 INT247762 Binding of Ccl2 and Ccrl2 1 0.19 0.29 0.12
47 INT171295 CXCL10 Positive_regulation of CCL5 1 0.04 0.06 0.12
48 INT247778 Ccl2 Regulation of Ccrl2 1 0.09 0 0.09
49 INT186767 Ccl11 Regulation of Ccl5 1 0.01 0 0.07
50 INT171297 TNF Positive_regulation of Localization of CCL5 1 0.17 0.66 0.07
51 INT186766 Il5 Regulation of Ccl5 1 0.01 0 0.07
52 INT247780 Ccrl2 Positive_regulation of Localization of IFN1@ 1 0.40 0.27 0.07
53 INT247776 Ccrl2 Positive_regulation of Localization of Gopc 1 0.14 0.27 0.07
54 INT246441 Ccl5 Positive_regulation of Gene_expression of Aif1 1 0.03 0.71 0.06
55 INT246436 Ccl5 Regulation of Aif1 1 0.01 0.67 0.06
56 INT247772 Rarres2 Regulation of Ccrl2 1 0.09 0 0.06
57 INT247756 Binding of Ccrl2 and Gopc 1 0.10 0 0.05
58 INT122216 IL1B Positive_regulation of CCL5 3 0.67 0.53 0.04
59 INT247771 Binding of Ccl7 and Ccrl2 1 0.17 0.29 0.04
60 INT247764 Ccrl2 Positive_regulation of Gene_expression of Fcer2a 1 0.01 0.29 0.04
61 INT247774 Binding of Ccl5 and Ccrl2 1 0.14 0.29 0.04
62 INT247757 Binding of Ccl8 and Ccrl2 1 0.16 0.29 0.04
63 INT171279 IL6 Positive_regulation of CCL5 1 0.04 0.38 0.04
64 INT171301 TNF Positive_regulation of CCL5 1 0.16 0.38 0.04
65 INT247766 Binding of Ccl2 and Ccl5 1 0.14 0.28 0.04
66 INT122217 IL1B Positive_regulation of Gene_expression of CCL5 2 0.52 0.08 0
67 INT247754 Regulation of Binding of Ccrl2 and Rarres2 1 0.17 0 0
68 INT127690 TNF Positive_regulation of Regulation of CCL5 1 0.33 0.17 0
69 INT171282 TNFSF12 Positive_regulation of Gene_expression of CCL5 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for chemokine receptor binding. They are ordered first by their pain relevance and then by number of times they were reported in chemokine receptor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
2 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
3 INT78901 Localization of CCL5 67 0.78 40.79 20.59
4 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
5 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83
6 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
7 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
8 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
9 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
10 INT181348 Localization of Ccl5 24 0.65 19.55 6.8
11 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
12 INT181363 Regulation of Ccl5 16 0.46 13.65 5.09
13 INT181362 Negative_regulation of Ccl5 21 0.40 15.63 4.96
14 INT82887 Positive_regulation of Ccl5 10 0.40 3.4 4.91
15 INT176614 Positive_regulation of Gene_expression of Ccl5 20 0.59 16.2 4.81
16 INT233493 Gene_expression of Ccrl2 59 0.65 11.61 4.71
17 INT89590 Negative_regulation of Gene_expression of Ccl5 8 0.36 3.97 4.67
18 INT181042 Binding of Ccl5 18 0.41 9.34 4.51
19 INT4239 Negative_regulation of CCL5 15 0.40 10.92 4.26
20 INT103281 Transcription of CCL5 10 0.67 5.95 3.7
21 INT89592 Localization of Ccl5 10 0.61 7.65 3.62
22 INT181378 Negative_regulation of Gene_expression of Ccl5 12 0.46 9.64 3.59
23 INT124123 Positive_regulation of Localization of CCL5 12 0.67 7 3.37
24 INT181418 Regulation of Gene_expression of Ccl5 11 0.52 9.86 3.37
25 INT82879 Regulation of Ccl5 9 0.30 6.19 3.17
26 INT78898 Regulation of Gene_expression of CCL5 9 0.42 5.7 3.11
27 INT115617 Binding of Ccl5 5 0.33 0.58 3.11
28 INT194661 Binding of CCL5 9 0.46 6.07 2.73
29 INT115616 Positive_regulation of Binding of Ccl5 3 0.25 0.59 2.04
30 INT103061 Positive_regulation of Gene_expression of Ccl5 4 0.35 1.67 1.9
31 INT194660 Positive_regulation of Binding of CCL5 1 0.42 2.74 1.72
32 INT78896 Negative_regulation of Localization of CCL5 8 0.57 2.43 1.59
33 INT171015 Positive_regulation of Positive_regulation of CCL5 3 0.42 3.63 1.51
34 INT115895 Phosphorylation of Ccl5 1 0.55 0 1.31
35 INT149554 Transcription of Ccl5 2 0.59 0.55 1.14
36 INT115893 Negative_regulation of Binding of Ccl5 1 0.37 0 1.14
37 INT208244 Regulation of Gene_expression of Ccl5 1 0.26 1.92 1.01
38 INT181351 Transcription of Ccl5 5 0.64 2.19 0.9
39 INT103285 Regulation of Localization of CCL5 3 0.44 1.11 0.89
40 INT149555 Negative_regulation of Positive_regulation of Ccl5 1 0.15 0 0.88
41 INT247731 Binding of Ccrl2 1 0.35 1.38 0.87
42 INT181390 Negative_regulation of Positive_regulation of Ccl5 2 0.31 2.31 0.77
43 INT233497 Positive_regulation of Ccrl2 2 0.58 2.7 0.74
44 INT115897 Positive_regulation of Phosphorylation of Ccl5 1 0.41 0 0.66
45 INT181349 Positive_regulation of Localization of Ccl5 2 0.37 0.89 0.62
46 INT247747 Regulation of Ccrl2 1 0.44 1.36 0.62
47 INT194225 Positive_regulation of Positive_regulation of Ccl5 1 0.07 1.13 0.55
48 INT233489 Regulation of Gene_expression of Ccrl2 4 0.38 0.74 0.49
49 INT312270 Positive_regulation of Xcl1 4 0.31 3.32 0.44
50 INT194658 Positive_regulation of Transcription of CCL5 1 0.45 0.68 0.44
51 INT267606 Protein_catabolism of CCL5 2 0.48 1.39 0.43
52 INT268760 Positive_regulation of Binding of Ccl5 1 0.13 0.91 0.39
53 INT322698 Protein_catabolism of Ccl5 1 0.49 0.33 0.38
54 INT233452 Positive_regulation of Gene_expression of Ccrl2 3 0.42 1.91 0.37
55 INT195733 Phosphorylation of CCL5 2 0.10 1.04 0.33
56 INT103283 Negative_regulation of Transcription of CCL5 1 0.50 0.28 0.27
57 INT322710 Positive_regulation of Transcription of Ccl5 1 0.43 0.56 0.26
58 INT325072 Gene_expression of Xcl1 1 0.33 0.88 0.24
59 INT282377 Regulation of Positive_regulation of CCL5 1 0.05 1.12 0.22
60 INT150203 Positive_regulation of Xcl1 2 0.40 2.47 0.21
61 INT318169 Regulation of Xcl1 1 0.15 1.14 0.19
62 INT15734 Negative_regulation of Xcl1 2 0.18 0 0.16
63 INT15735 Positive_regulation of Negative_regulation of Xcl1 1 0.02 0 0.16
64 INT89593 Negative_regulation of Localization of Ccl5 1 0.03 0.46 0.15
65 INT233838 Regulation of Binding of Ccl5 1 0.21 1 0.15
66 INT195730 Negative_regulation of Binding of CCL5 1 0.05 0.51 0.13
67 INT246434 Negative_regulation of Negative_regulation of Ccl5 1 0.40 1.72 0.09
68 INT247725 Negative_regulation of Gene_expression of Ccrl2 1 0.27 0.47 0.09
69 INT247748 Localization of Ccrl2 1 0.54 0.35 0.07
70 INT325069 Regulation of Gene_expression of Xcl1 1 0.19 0 0.04
71 INT325073 Positive_regulation of Gene_expression of Xcl1 1 0.19 0 0.03
72 INT247713 Transcription of Ccrl2 1 0.34 0.21 0.03
73 INT325070 Negative_regulation of Positive_regulation of Xcl1 1 0.18 0 0
74 INT325068 Negative_regulation of Gene_expression of Xcl1 1 0.16 0.09 0
75 INT247744 Negative_regulation of Binding of Ccrl2 1 0.27 0 0
76 INT247726 Positive_regulation of Localization of Ccrl2 1 0.32 0 0
77 INT189478 Regulation of Transcription of Ccl5 1 0.38 0.63 0
78 INT325071 Binding of Xcl1 1 0.13 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox