GO:0042383

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Name sarcolemma
Categary Component
Go Slim No
Go Link GO:0042383
Unique Molecular Interactions 1229
Total Molecular Interactions 1664
Total Single Events 19151
Pain Genes Associated 113

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sarcolemma. They are ordered first by their pain relevance and then by number of times they were reported for sarcolemma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22
3 INT40114 Binding of OPRD1 and Oprm1 2 0.00 0 4.29
4 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
5 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
6 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
7 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
8 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
9 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
10 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
11 INT108472 Binding of NOS1 and PNOC 1 0.32 0.64 3.27
12 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
13 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
14 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
15 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
16 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03
17 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
18 INT130085 Crp Positive_regulation of Gene_expression of Vcam1 1 0.23 4.34 2.84
19 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
20 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
21 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68
22 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
23 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
24 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54
25 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 0.07 1.72 2.46
26 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
27 INT154226 Positive_regulation of Oprk1 Negative_regulation of Negative_regulation of Oprm1 1 0.28 0.07 2.32
28 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
29 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
30 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
31 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
32 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
33 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
34 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
35 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95
36 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
37 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93
38 INT169498 Binding of Oprm1 and Mirlet7a-1 1 0.32 0 1.9
39 INT153582 Binding of Oprm1 and Hint1 1 0.01 0 1.87
40 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 0.09 0 1.86
41 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
42 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84
43 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84
44 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
45 INT169502 Mirlet7a-1 Regulation of Oprm1 1 0.53 0 1.81
46 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
47 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
48 INT168925 Binding of Oprm1 and Imraq2 1 0.04 0.13 1.78
49 INT168924 Positive_regulation of Binding of Oprm1 and Imraq2 1 0.06 0.13 1.78
50 INT211746 Binding of Oprm1 and Mors1 1 0.08 0 1.78
51 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
52 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72
53 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
54 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
55 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66
56 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
57 INT315180 Gene_expression of Mors1 Positive_regulation of Gene_expression of Oprm1 1 0.03 0.48 1.64
58 INT187175 Binding of BSG and PPIA 1 0.14 2.23 1.64
59 INT315181 Gene_expression of Mors1 Positive_regulation of Oprm1 1 0.03 0.48 1.64
60 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 0.16 0.92 1.63
61 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63
62 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
63 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
64 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
65 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
66 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59
67 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
68 INT12327 Igh-Dex Positive_regulation of Plec 1 0.03 0.73 1.57
69 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
70 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56
71 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
72 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
73 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55
74 INT111828 UPB1 Positive_regulation of Oprm1 1 0.00 0.85 1.53
75 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
76 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
77 INT8735 Oprm1 Positive_regulation of Scn4a 1 0.00 0 1.49
78 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46
79 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
80 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
81 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
82 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
83 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
84 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
85 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43
86 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43
87 INT43814 Binding of Cpe and Oprm1 1 0.08 0 1.41
88 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
89 INT142852 Oprm1 Positive_regulation of Oprd1 1 0.41 0.06 1.41
90 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
91 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
92 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
93 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
94 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35
95 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
96 INT38624 Binding of Oprm1 and Insrr 2 0.01 0.24 1.31
97 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
98 INT130786 Positive_regulation of Oprm1 Positive_regulation of Arc 1 0.27 0.9 1.31
99 INT168229 Oprm1 Regulation of Cea 1 0.10 0.26 1.3
100 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29
101 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
102 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
103 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
104 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
105 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
106 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
107 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
108 INT207548 U Negative_regulation of Gene_expression of Oprm1 1 0.01 0.46 1.26
109 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26
110 INT87375 Binding of Gabrg1 and Oprm1 1 0.00 0.83 1.25
111 INT162165 WDTC1 Positive_regulation of PLD2 1 0.50 0 1.25
112 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
113 INT86090 SCN5A Negative_regulation of Positive_regulation of Abat 1 0.00 0 1.25
114 INT126801 Regulation of Binding of Oprm1 and Penk 1 0.34 0.4 1.25
115 INT132465 Ltf Positive_regulation of Nos1 1 0.35 0.05 1.24
116 INT151444 Binding of Oprm1 and Pag1 1 0.00 1.5 1.24
117 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24
118 INT136257 Tff3 Regulation of SGCG 1 0.00 0.18 1.24
119 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
120 INT125857 Insrr Negative_regulation of Oprm1 1 0.01 0.27 1.24
121 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
122 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
123 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
124 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
125 INT58140 Binding of AP2M1 and Oprm1 1 0.01 0.4 1.23
126 INT76165 IGKV2-30 Positive_regulation of Phosphorylation of Oprm1 1 0.00 0.08 1.22
127 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
128 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
129 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
130 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
131 INT124157 Oprm1 Negative_regulation of Gnb5 1 0.25 0.4 1.19
132 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
133 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
134 INT49956 OPRM1 Positive_regulation of SGCG 1 0.53 0.3 1.18
135 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
136 INT153588 Binding of HINT1 and Oprm1 1 0.06 0 1.17
137 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
138 INT88778 Binding of Oprm1 and Pomc 3 0.21 0.56 1.14
139 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14
140 INT35399 Binding of Alox5 and Mthfs 1 0.01 0 1.14
141 INT68160 Alox5 Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.13
142 INT110671 Binding of Cnr1 and Alox5 1 0.07 0.2 1.13
143 INT68164 Mthfs Positive_regulation of Positive_regulation of Alox5 1 0.00 0.64 1.13
144 INT68167 Alox5 Positive_regulation of Positive_regulation of Mthfs 1 0.00 0.64 1.13
145 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
146 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
147 INT110669 Binding of Alox5 and Trpv1 1 0.07 0.2 1.13
148 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13
149 INT68156 Pla2g1b Positive_regulation of Positive_regulation of Alox5 1 0.03 0.64 1.13
150 INT110522 Oprm1 Positive_regulation of Oprk1 1 0.11 0 1.12
151 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12
152 INT142572 D5Pas1 Negative_regulation of Nos1 2 0.02 0.14 1.11
153 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
154 INT69338 Binding of Oprd1 and Oprm1 1 0.24 0.26 1.11
155 INT317527 Binding of Hint1 and Nos1 1 0.27 0.1 1.11
156 INT133497 Binding of Oprm1 and Cckbr 1 0.03 0 1.1
157 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
158 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09
159 INT114007 Binding of Crygs and Oprm1 1 0.03 0 1.09
160 INT187176 Binding of BSG and MMP1 1 0.09 1.18 1.08
161 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
162 INT81582 Plec Positive_regulation of st 1 0.02 0 1.07
163 INT81581 Plec Positive_regulation of Nudt14 1 0.01 0 1.07
164 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06
165 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
166 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
167 INT312097 ELANE Regulation of ALOX5 1 0.08 1.75 1.05
168 INT145906 Elane Regulation of Transcription of Oprm1 1 0.10 0.14 1.04
169 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
170 INT132464 Ltf Negative_regulation of Positive_regulation of Nos1 1 0.33 0 1.03
171 INT150621 Binding of Oprm1 and Oprd1 1 0.00 0.08 1.02
172 INT98555 Oprm1 Positive_regulation of Casp8 1 0.51 0.36 1.02
173 INT106956 Oprm1 Positive_regulation of Positive_regulation of P9Ehs1 1 0.08 0.54 1.02
174 INT116751 Positive_regulation of Oprm1 Positive_regulation of Pik3cd 1 0.28 0.38 1.01
175 INT119914 Olr1714 Negative_regulation of Nos1 1 0.02 0.47 1.01
176 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
177 INT98002 Positive_regulation of Oprm1 Positive_regulation of P9Ehs1 1 0.10 0 1
178 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
179 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
180 INT70105 SCD Positive_regulation of Oprm1 1 0.01 0 1
181 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
182 INT317555 Nos1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
183 INT317544 Camk2a Regulation of Negative_regulation of Oprm1 1 0.20 0.07 1
184 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
185 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1
186 INT169500 Negative_regulation of Mirlet7a-1 Regulation of Oprm1 1 0.37 0 0.99
187 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99
188 INT59518 YY1 Positive_regulation of SGCG 1 0.50 0.32 0.99
189 INT69307 Prkcq Negative_regulation of TH1L 1 0.00 0.98 0.98
190 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
191 INT57555 Binding of Oprm1 and Oprl1 2 0.06 0.05 0.97
192 INT137920 Binding of Kdr and Oprm1 1 0.23 0 0.97
193 INT317543 Pag1 Positive_regulation of Oprm1 1 0.12 0.73 0.97
194 INT137919 Binding of Oprm1 and Stat3 1 0.30 0 0.97
195 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
196 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96
197 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
198 INT166842 Binding of ANXA1 and Nfkb1 1 0.37 1.64 0.95
199 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
200 INT12373 SCN5A Negative_regulation of Cpe 1 0.00 0 0.94

Single Events

The table below shows the top 100 pain related interactions that have been reported for sarcolemma. They are ordered first by their pain relevance and then by number of times they were reported in sarcolemma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29
2 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71
3 INT6406 Binding of Oprm1 280 0.48 40.54 226.26
4 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
5 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85
6 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1
7 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
8 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
9 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
10 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85
11 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71
12 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76
13 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
14 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
15 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32
16 INT8733 Localization of Oprm1 61 0.75 7.55 64.61
17 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61
18 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87
19 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83
20 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65
21 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82
22 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
23 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64
24 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
25 INT62521 Phosphorylation of Oprm1 44 0.82 2.66 47.45
26 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01
27 INT88081 Negative_regulation of Gene_expression of Oprm1 45 0.59 16.56 37.5
28 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
29 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
30 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
31 INT21560 Positive_regulation of Binding of Oprm1 30 0.50 7.16 32.95
32 INT16290 Gene_expression of BSG 60 0.68 38.73 32.86
33 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4
34 INT5418 Negative_regulation of Alox5 108 0.57 42.09 31.17
35 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22
36 INT9053 Negative_regulation of ALOX5 97 0.58 40.34 29.94
37 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72
38 INT16769 Positive_regulation of Positive_regulation of Oprm1 31 0.57 8.29 29.66
39 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63
40 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
41 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75
42 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
43 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96
44 INT48766 Regulation of NOS1 73 0.61 37.01 24.59
45 INT49172 Regulation of Nos1 43 0.52 27.53 23.66
46 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48
47 INT1221 Regulation of SGCG 65 0.60 24.21 22.94
48 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79
49 INT57253 Negative_regulation of Binding of Oprm1 24 0.43 5.27 22.67
50 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73
51 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72
52 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
53 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72
54 INT49835 Negative_regulation of Positive_regulation of Oprm1 21 0.42 4.11 20.11
55 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85
56 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29
57 INT17442 Gene_expression of ALOX5 110 0.75 51.55 18.29
58 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88
59 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66
60 INT3364 Binding of SGCG 87 0.47 31.93 17.24
61 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78
62 INT33915 Regulation of Positive_regulation of Oprm1 22 0.60 2.44 16.43
63 INT114025 Transcription of Nos1 20 0.70 16.48 15.63
64 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25
65 INT68811 Regulation of Transcription of Oprm1 19 0.61 3.67 15.15
66 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06
67 INT12658 Regulation of Binding of Oprm1 9 0.57 2.44 14.95
68 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82
69 INT64112 Regulation of Gene_expression of Nos1 22 0.62 21.45 14.76
70 INT23344 Gene_expression of Alox5 60 0.75 28.2 13.82
71 INT68814 Positive_regulation of Transcription of Oprm1 16 0.60 2.72 13.57
72 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52
73 INT12325 Gene_expression of Plec 47 0.72 11.92 13.35
74 INT62523 Positive_regulation of Phosphorylation of Oprm1 11 0.53 0.75 12.51
75 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47
76 INT73829 Positive_regulation of Gene_expression of VCAM1 41 0.61 35.96 11.92
77 INT80251 Binding of Nos1 21 0.30 8.24 11.31
78 INT25963 Gene_expression of DES 122 0.75 98.81 11.25
79 INT6044 Regulation of Binding of Oprm1 16 0.61 3.01 11.11
80 INT59766 Positive_regulation of Negative_regulation of Oprm1 9 0.50 1.31 11.08
81 INT48912 Localization of NOS1 52 0.77 24.14 10.92
82 INT109651 Negative_regulation of Aqp4 23 0.53 8.5 10.7
83 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52
84 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42
85 INT71592 Negative_regulation of Gene_expression of Oprm1 11 0.58 4.03 10.37
86 INT110017 Phosphorylation of Nos1 12 0.60 1.64 10.3
87 INT48131 Gene_expression of Slc2a4 32 0.78 14.64 10.16
88 INT17421 Negative_regulation of Alox5 41 0.57 15.23 10.05
89 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84
90 INT75919 Gene_expression of Slc8a1 23 0.63 16.44 9.84
91 INT62544 Gene_expression of Anxa1 21 0.47 13.56 9.71
92 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
93 INT62919 Regulation of Gnas 22 0.43 5.61 9.55
94 INT49483 Regulation of Positive_regulation of Oprm1 8 0.61 2.34 9.4
95 INT62829 Positive_regulation of VCAM1 39 0.70 38.42 9.15
96 INT35269 Localization of SGCG 38 0.78 14.68 9.01
97 INT20835 Negative_regulation of Negative_regulation of Oprm1 10 0.43 0.56 8.96
98 INT9889 Gene_expression of Alox5 34 0.63 20.83 8.85
99 INT29411 Positive_regulation of ADRB2 13 0.65 5.42 8.78
100 INT3622 Regulation of CTSB 34 0.58 16.08 8.76
101 INT76162 Positive_regulation of Phosphorylation of Oprm1 11 0.69 0.64 8.72
102 INT98835 Positive_regulation of Transcription of Oprm1 15 0.65 2.47 8.67
103 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58
104 INT168096 Transcription of Cav3 1 0.72 7.23 8.58
105 INT48908 Transcription of NOS1 27 0.55 13.46 8.39
106 INT18021 Positive_regulation of Binding of Oprm1 16 0.70 2.53 8.38
107 INT84672 Negative_regulation of Positive_regulation of Nos1 12 0.48 3.76 8.27
108 INT114023 Positive_regulation of Transcription of Nos1 7 0.60 5.35 8.06
109 INT71381 Localization of Nos1 33 0.79 11.46 8.05
110 INT91238 Regulation of Negative_regulation of Oprm1 6 0.45 1.4 7.85
111 INT99430 Positive_regulation of Gene_expression of Slc2a4 18 0.66 10.45 7.79
112 INT62372 Positive_regulation of Localization of Oprm1 8 0.50 0.46 7.71
113 INT81399 Regulation of Vcam1 24 0.46 23.53 7.68
114 INT49104 Positive_regulation of Gene_expression of Vcam1 30 0.69 36.52 7.64
115 INT7168 Positive_regulation of Ctsb 9 0.70 0.3 7.58
116 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4
117 INT7883 Binding of ADRB2 18 0.47 5.49 7.37
118 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3
119 INT16628 Negative_regulation of Positive_regulation of Oprm1 9 0.43 0.89 6.92
120 INT62524 Negative_regulation of Phosphorylation of Oprm1 7 0.59 0.08 6.92
121 INT75228 Positive_regulation of Negative_regulation of Oprm1 8 0.49 0.95 6.9
122 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
123 INT92741 Positive_regulation of Positive_regulation of Nos1 8 0.47 1.44 6.58
124 INT5932 Regulation of Regulation of Oprm1 7 0.61 0.44 6.47
125 INT107737 Positive_regulation of Pld2 11 0.67 0.33 6.45
126 INT134290 Positive_regulation of PLD2 10 0.68 3.06 6.44
127 INT67890 Positive_regulation of Gene_expression of SGCG 26 0.67 9.91 6.41
128 INT81443 Positive_regulation of Vcam1 29 0.63 28.4 6.35
129 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33
130 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32
131 INT127023 Negative_regulation of Gene_expression of Vcam1 24 0.59 20.39 6.28
132 INT47127 Gene_expression of BGN 11 0.75 17.09 6.25
133 INT69499 Binding of Nos1 15 0.36 2.56 6.23
134 INT93658 Transcription of Nos1 16 0.72 6.85 6.16
135 INT53135 Positive_regulation of Localization of Oprm1 2 0.50 0 6.12
136 INT101008 Gene_expression of Scn5a 5 0.75 26.93 6.06
137 INT64111 Negative_regulation of Gene_expression of Nos1 22 0.57 8.96 6.02
138 INT48911 Binding of NOS1 24 0.40 11.21 5.89
139 INT257199 Positive_regulation of Phosphorylation of Nos1 2 0.45 0.68 5.78
140 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
141 INT1243 Regulation of ADRB2 16 0.54 1.84 5.66
142 INT84673 Localization of Nos1 19 0.80 5.01 5.62
143 INT268043 Gene_expression of Abcc8 30 0.71 3.05 5.61
144 INT112927 Negative_regulation of Localization of Oprm1 4 0.39 0.31 5.59
145 INT155348 Positive_regulation of Aqp4 14 0.63 9.92 5.53
146 INT28164 Regulation of ALOX5 25 0.60 12.76 5.47
147 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45
148 INT28165 Positive_regulation of ALOX5 38 0.47 10.8 5.37
149 INT23598 Binding of SCN5A 32 0.40 16 5.35
150 INT30209 Localization of SCN5A 24 0.72 7.95 5.35
151 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34
152 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
153 INT50105 Localization of CTSB 29 0.78 10.98 5.21
154 INT86717 Negative_regulation of Positive_regulation of NOS1 18 0.30 8.88 5.2
155 INT13885 Positive_regulation of Adrb2 9 0.49 1.11 5.12
156 INT6577 Regulation of Alox5 18 0.47 9.19 5.06
157 INT187189 Positive_regulation of Gene_expression of BSG 1 0.61 6.21 5.02
158 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
159 INT221226 Gene_expression of Kcnj8 23 0.58 1.69 4.84
160 INT7170 Positive_regulation of Positive_regulation of Ctsb 1 0.40 0 4.76
161 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
162 INT83623 Gene_expression of Cd59 7 0.76 7.35 4.7
163 INT30355 Positive_regulation of Gene_expression of Alox5 10 0.67 14.61 4.69
164 INT15995 Positive_regulation of Alox5 18 0.49 3.94 4.63
165 INT75761 Positive_regulation of Phosphorylation of Plcb3 1 0.05 0.22 4.58
166 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
167 INT115805 Gene_expression of PLD2 7 0.76 12.49 4.51
168 INT205272 Positive_regulation of Gene_expression of Plec 11 0.43 1.5 4.49
169 INT24930 Binding of Adrb2 6 0.26 4.18 4.44
170 INT75759 Phosphorylation of Plcb3 1 0.06 0.22 4.42
171 INT62821 Negative_regulation of Gene_expression of VCAM1 21 0.54 12.24 4.41
172 INT76581 Regulation of Negative_regulation of NOS1 14 0.45 7.49 4.4
173 INT98357 Binding of Gnas 11 0.41 1.87 4.35
174 INT130083 Positive_regulation of Positive_regulation of Vcam1 8 0.36 5.81 4.31
175 INT143337 Binding of Aqp4 30 0.40 23.73 4.24
176 INT160023 Regulation of Aqp4 9 0.45 8.41 4.19
177 INT105998 Protein_catabolism of Oprm1 5 0.95 0.88 4.08
178 INT74365 Positive_regulation of Alox5 19 0.47 11.03 4.04
179 INT484 Negative_regulation of ADRB2 13 0.59 2.85 3.94
180 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79
181 INT54848 Protein_catabolism of SGCG 12 0.96 3.8 3.78
182 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77
183 INT225965 Localization of Aqp4 26 0.81 18.85 3.75
184 INT129312 Gene_expression of SGCB 24 0.76 18.25 3.75
185 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
186 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
187 INT85497 Gene_expression of Anxa1 6 0.77 4.7 3.68
188 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
189 INT44254 Regulation of Gene_expression of ALOX5 12 0.43 7.06 3.65
190 INT16165 Regulation of DMD 114 0.60 35.13 3.64
191 INT185148 Negative_regulation of BGN 3 0.20 1.23 3.56
192 INT106264 Negative_regulation of Gene_expression of Vcam1 13 0.53 10.47 3.55
193 INT6882 Binding of Adrb2 5 0.47 1.97 3.55
194 INT130836 Transcription of Aqp4 6 0.72 5.93 3.52
195 INT20265 Gene_expression of Ctsb 3 0.47 1.01 3.52
196 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
197 INT102076 Regulation of DST 15 0.22 10 3.5
198 INT5929 Positive_regulation of Regulation of Oprm1 4 0.50 0.56 3.48
199 INT67468 Regulation of SCN5A 27 0.44 4.4 3.47
200 INT134875 Phosphorylation of Nos1 5 0.70 1.21 3.44
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