GO:0042384

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Name cilium assembly
Categary Process
Go Slim No
Go Link GO:0042384
Unique Molecular Interactions 71
Total Molecular Interactions 84
Total Single Events 579
Pain Genes Associated 25

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cilium assembly. They are ordered first by their pain relevance and then by number of times they were reported for cilium assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72
2 INT306823 Binding of E2F4 and GOPC 1 0.06 0.23 0.91
3 INT306831 Positive_regulation of Binding of E2F4 and NOLC1 1 0.10 0.46 0.85
4 INT306826 Binding of E2F4 and NOLC1 1 0.08 0.41 0.84
5 INT139893 Binding of Alb and Alms1 1 0.04 0.48 0.75
6 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7
7 INT52478 Binding of Adarb1 and Ift172 1 0.00 0 0.62
8 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
9 INT145726 Binding of Abcb1a and Alms1 1 0.32 0.48 0.56
10 INT104016 RPGR Positive_regulation of Gene_expression of FOS 1 0.16 0 0.43
11 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
12 INT93989 Rab8a Positive_regulation of Gene_expression of Il12a 1 0.10 0.48 0.3
13 INT93986 Rab8a Positive_regulation of Gene_expression of Il6 1 0.08 0.48 0.3
14 INT93988 Rab8a Regulation of Hand2 1 0.09 0.78 0.3
15 INT93990 Rab8a Positive_regulation of Gene_expression of Il1 1 0.05 0.48 0.3
16 INT93987 Positive_regulation of Rab8a Positive_regulation of Localization of Ifng 1 0.10 0.38 0.29
17 INT298501 Paf Regulation of Negative_regulation of Alms1 1 0.00 0.63 0.29
18 INT145618 Binding of Fez1 and Kif27 1 0.13 0.25 0.27
19 INT268279 Positive_regulation of Binding of Aggf1 and Alms1 1 0.02 0.15 0.18
20 INT268280 Binding of Aggf1 and Alms1 1 0.01 0.15 0.18
21 INT231244 Binding of Fus and Alms1 1 0.20 0.57 0.17
22 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17
23 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17
24 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17
25 INT338449 Nps Regulation of Alms1 1 0.04 0.13 0.14
26 INT308534 Binding of HIVEP1 and Alms1 1 0.00 0.96 0.13
27 INT241910 Binding of Alb and Alms1 1 0.02 0.52 0.13
28 INT100478 Binding of Camk1d and Alms1 1 0.17 0 0.12
29 INT187468 Alms1 Positive_regulation of H2-D1 1 0.02 0.32 0.11
30 INT327792 Binding of IGFALS and Alms1 1 0.00 1.15 0.11
31 INT211921 Gene_expression of Nek1 Positive_regulation of Cat 1 0.01 0.26 0.1
32 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09
33 INT243213 Myst2 Negative_regulation of Alms1 1 0.01 0.91 0.08
34 INT229493 Binding of Ndel1 and Disc1 1 0.13 0.68 0.06
35 INT350010 Binding of IL6 and AHI1 1 0.01 0.29 0.06
36 INT340427 Positive_regulation of P2rx7 Positive_regulation of Regulation of Pkhd1 1 0.01 1 0.05
37 INT169962 Binding of Rb1 and E2f4 1 0.25 0.56 0.04
38 INT169960 Binding of Rbl2 and E2f4 1 0.27 1.06 0.04
39 INT251067 Plvap Regulation of Protein_catabolism of Alms1 1 0.03 0 0.03
40 INT229508 Binding of Fez1 and Disc1 1 0.03 0.34 0.03
41 INT251074 Cldn3 Regulation of Protein_catabolism of Alms1 1 0.09 0 0.03
42 INT299368 Mkks Positive_regulation of Mapk8 1 0.41 0.17 0.03
43 INT283346 Binding of Srr and Kif3a 1 0.17 0 0
44 INT251071 Cldn3 Negative_regulation of Alms1 1 0.09 0.26 0
45 INT200058 Binding of Ndn and Bbs4 1 0.30 0.29 0
46 INT353544 Egf Regulation of Gene_expression of ONECUT1 1 0.00 0.08 0
47 INT269944 Gata6 Regulation of Gene_expression of Foxj1 1 0.19 0 0
48 INT327830 Alms1 Positive_regulation of Aqp4 1 0.03 0.15 0
49 INT273106 Binding of Mtor and Cby1 1 0.01 0 0
50 INT86001 Binding of Pnp and Alms1 1 0.03 0 0
51 INT104029 RPGRIP1L Negative_regulation of Gene_expression of LTB 1 0.16 0.06 0
52 INT284391 Binding of AMT and Alms1 1 0.00 0 0
53 INT305884 Atp6v0a2 Regulation of Alms1 1 0.00 0 0
54 INT200062 Binding of Ngfr and Bbs4 1 0.30 0.3 0
55 INT86004 Binding of PBCA and Alms1 1 0.01 0 0
56 INT269933 Foxa2 Regulation of Gene_expression of Foxj1 1 0.27 0 0
57 INT353542 Pik3cb Regulation of Gene_expression of ONECUT1 1 0.00 0.08 0
58 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0
59 INT186401 Binding of MKKS and MKS1 1 0.09 0.07 0
60 INT235692 Clcn1 Positive_regulation of Binding of Alms1 1 0.05 0.9 0
61 INT286589 Binding of PKHD1 and Pkd2 1 0.09 0.52 0
62 INT186402 Binding of KCNA1 and MKS1 1 0.05 0.07 0
63 INT269939 Foxa1 Regulation of Gene_expression of Foxj1 1 0.26 0 0
64 INT353543 Hgf Regulation of Gene_expression of ONECUT1 1 0.00 0.08 0
65 INT305882 Binding of Pcx and Alms1 1 0.03 0.62 0
66 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cilium assembly. They are ordered first by their pain relevance and then by number of times they were reported in cilium assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93
2 INT36177 Binding of Alms1 70 0.31 35.47 13.81
3 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68
4 INT35801 Regulation of Alms1 34 0.38 20.88 12.38
5 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1
6 INT10478 Protein_catabolism of Alms1 25 0.47 12.95 7.19
7 INT108761 Localization of Alms1 24 0.70 13.92 3.74
8 INT117336 Gene_expression of Nek1 2 0.02 8.56 2.31
9 INT306869 Gene_expression of E2F4 1 0.58 1.1 2.11
10 INT173512 Positive_regulation of Gene_expression of Alms1 12 0.44 8.66 1.95
11 INT306853 Binding of E2F4 1 0.28 1.37 1.63
12 INT93980 Gene_expression of Rab8a 1 0.74 2.72 1.21
13 INT21670 Localization of Lama5 1 0.31 1.11 1.1
14 INT134859 Gene_expression of Lama5 3 0.39 4.47 1.06
15 INT235929 Regulation of Positive_regulation of Alms1 2 0.02 2.84 1.02
16 INT142813 Localization of RPGRIP1L 1 0.59 0.99 1.01
17 INT173514 Negative_regulation of Gene_expression of Alms1 3 0.06 3.49 0.91
18 INT306888 Positive_regulation of Binding of E2F4 1 0.37 0.58 0.87
19 INT229278 Positive_regulation of Cby1 5 0.67 8.07 0.85
20 INT306840 Positive_regulation of Gene_expression of E2F4 1 0.37 0.58 0.82
21 INT230493 Regulation of Binding of Alms1 3 0.12 1.89 0.76
22 INT123290 Phosphorylation of Mks1 1 0.02 0.36 0.72
23 INT168981 Negative_regulation of Disc1 2 0.52 2.93 0.7
24 INT174517 Localization of AHI1 2 0.24 1.62 0.68
25 INT95337 Negative_regulation of AHI1 2 0.02 0.75 0.68
26 INT93981 Positive_regulation of Rab8a 1 0.66 1.41 0.67
27 INT306884 Negative_regulation of E2F4 1 0.44 0.61 0.62
28 INT155210 Positive_regulation of Phosphorylation of MKS1 1 0.00 0.07 0.58
29 INT289903 Regulation of Localization of Alms1 2 0.14 1.48 0.56
30 INT155209 Phosphorylation of MKS1 1 0.00 0.07 0.55
31 INT168982 Negative_regulation of Negative_regulation of Disc1 1 0.42 1.28 0.54
32 INT230495 Regulation of Gene_expression of Alms1 4 0.04 4.53 0.53
33 INT354813 Positive_regulation of Negative_regulation of Alms1 1 0.04 0.82 0.48
34 INT242443 Positive_regulation of Localization of Alms1 2 0.09 0.66 0.46
35 INT93985 Positive_regulation of Gene_expression of Rab8a 1 0.39 1.08 0.45
36 INT93983 Binding of Rab8a 1 0.31 1.05 0.44
37 INT93982 Negative_regulation of Rab8a 1 0.35 1.08 0.44
38 INT93979 Negative_regulation of Gene_expression of Rab8a 1 0.48 1.03 0.42
39 INT306864 Negative_regulation of Gene_expression of E2F4 1 0.32 0.28 0.41
40 INT308524 Regulation of Protein_catabolism of Alms1 1 0.06 1.04 0.4
41 INT306859 Localization of E2F4 1 0.56 0.65 0.4
42 INT7597 Positive_regulation of Lama5 1 0.01 0.34 0.35
43 INT185351 Positive_regulation of Nek1 2 0.04 2.11 0.34
44 INT346261 Gene_expression of MKKS 1 0.40 0.66 0.34
45 INT154243 Positive_regulation of Binding of Alms1 4 0.42 1.86 0.32
46 INT229279 Negative_regulation of Cby1 15 0.42 9.4 0.31
47 INT346249 Phosphorylation of MKKS 1 0.43 0.61 0.31
48 INT93984 Positive_regulation of Positive_regulation of Rab8a 1 0.48 0.34 0.27
49 INT243208 Negative_regulation of Protein_catabolism of Alms1 2 0.06 2.21 0.26
50 INT106807 Binding of Lama5 2 0.08 1.71 0.24
51 INT295891 Positive_regulation of Positive_regulation of Alms1 1 0.02 0.48 0.2
52 INT356020 Binding of MKS1 1 0.02 1.36 0.2
53 INT296875 Positive_regulation of AHI1 2 0.15 3.53 0.16
54 INT251975 Positive_regulation of Pkhd1 5 0.10 8.98 0.15
55 INT134860 Negative_regulation of Gene_expression of Lama5 1 0.15 0.33 0.15
56 INT76794 Gene_expression of AHI1 3 0.04 1.69 0.14
57 INT259191 Positive_regulation of Disc1 1 0.44 1.46 0.14
58 INT163225 Gene_expression of Bbs4 1 0.60 0.09 0.13
59 INT163230 Gene_expression of Mkks 1 0.48 0.09 0.13
60 INT243206 Negative_regulation of Localization of Alms1 1 0.05 0.98 0.12
61 INT106806 Negative_regulation of Binding of Lama5 1 0.09 1.03 0.09
62 INT235892 Gene_expression of Cby1 1 0.65 0 0.08
63 INT251894 Regulation of Regulation of Lama5 1 0.01 1.07 0.08
64 INT251895 Regulation of Lama5 1 0.01 1.06 0.08
65 INT229283 Negative_regulation of Positive_regulation of Cby1 1 0.42 0.18 0.07
66 INT353541 Gene_expression of ONECUT1 1 0.01 0.15 0.07
67 INT76793 Regulation of Gene_expression of AHI1 1 0.00 0.13 0.07
68 INT145889 Positive_regulation of Gene_expression of AHI1 1 0.01 0.47 0.07
69 INT344823 Negative_regulation of Negative_regulation of Alms1 1 0.04 1.04 0.07
70 INT344812 Negative_regulation of Binding of Alms1 1 0.04 1.04 0.07
71 INT183818 Positive_regulation of MKKS 1 0.01 1.82 0.05
72 INT340406 Regulation of Pkhd1 1 0.01 0.99 0.05
73 INT251896 Negative_regulation of Lama5 1 0.01 0.82 0.03
74 INT351638 Gene_expression of Cby1 1 0.00 0.68 0.03
75 INT286581 Gene_expression of PKHD1 1 0.24 0.19 0.03
76 INT283314 Localization of Kif3a 1 0.69 0 0.03
77 INT340405 Gene_expression of Pkhd1 1 0.03 1.14 0.03
78 INT286580 Positive_regulation of Gene_expression of PKHD1 1 0.16 0.1 0.03
79 INT292996 Binding of Pkhd1 3 0.07 3.12 0
80 INT356021 Gene_expression of MKS1 1 0.04 3.38 0
81 INT235893 Negative_regulation of Cby1 1 0.42 0.42 0
82 INT291287 Positive_regulation of Positive_regulation of RPGR 1 0.45 0.13 0
83 INT268410 Positive_regulation of MKS1 1 0.03 0 0
84 INT268404 Regulation of MKS1 1 0.04 1.15 0
85 INT239508 Transcription of Alms1 1 0.20 0 0
86 INT283316 Gene_expression of Kif3a 1 0.55 0 0
87 INT286588 Positive_regulation of Localization of PKHD1 1 0.16 0.79 0
88 INT178413 Binding of Cby1 1 0.01 0.51 0
89 INT269905 Positive_regulation of Foxj1 1 0.32 0.08 0
90 INT169925 Localization of E2f4 1 0.55 0.08 0
91 INT291286 Positive_regulation of RPGR 1 0.45 0.13 0
92 INT169922 Binding of E2f4 1 0.25 0.08 0
93 INT286576 Binding of PKHD1 1 0.12 0.63 0
94 INT304591 Protein_catabolism of MKS1 1 0.86 0.49 0
95 INT283315 Positive_regulation of Kif3a 1 0.46 0 0
96 INT268408 Transcription of MKS1 1 0.04 0.1 0
97 INT169938 Gene_expression of E2f4 1 0.46 0.07 0
98 INT283328 Binding of Kif3a 1 0.34 0 0
99 INT286584 Positive_regulation of PKHD1 1 0.13 1.01 0
100 INT269900 Gene_expression of Foxj1 1 0.49 0.25 0
101 INT248200 Gene_expression of Disc1 1 0.51 0.54 0
102 INT169915 Regulation of Gene_expression of E2f4 1 0.19 0 0
103 INT286579 Localization of PKHD1 1 0.24 0.79 0
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