GO:0042393

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Name histone binding
Categary Function
Go Slim Yes
Go Link GO:0042393
Unique Molecular Interactions 212
Total Molecular Interactions 262
Total Single Events 2103
Pain Genes Associated 36

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for histone binding. They are ordered first by their pain relevance and then by number of times they were reported for histone binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
2 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
3 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
4 INT168865 Cd38 Regulation of Wdtc1 1 0.03 0.12 1.35
5 INT90385 EXTL3 Regulation of Ctsl 1 0.00 1.1 0.98
6 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
7 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
8 INT141605 Gene_expression of Ctsl Positive_regulation of Positive_regulation of MET 1 0.34 0 0.8
9 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
10 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
11 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
12 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
13 INT40134 Binding of Pomc and Noc2l 1 0.01 0.08 0.7
14 INT184405 CRP Positive_regulation of Gene_expression of ASF1A 1 0.03 1.17 0.49
15 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
16 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
17 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
18 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
19 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
20 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
21 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
22 INT135426 Binding of APBB1 and Dlg4 1 0.00 0.17 0.42
23 INT40208 Binding of Eef1a1 and Hils1 1 0.01 0.22 0.42
24 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
25 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
26 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
27 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
28 INT303994 Il6 Positive_regulation of JAK2 1 0.03 0.41 0.37
29 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
30 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
31 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
32 INT28688 Binding of Kng1 and Ctsl1 1 0.15 0 0.31
33 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
34 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
35 INT198926 Binding of Apbb1 and Lrp1 5 0.12 2.18 0.24
36 INT139050 Negative_regulation of AR Negative_regulation of Phosphorylation of PRKCB 1 0.02 0.34 0.23
37 INT223570 Binding of Mri1 and Uhrf2 1 0.02 0.56 0.22
38 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21
39 INT45934 PKN1 Regulation of NOTCH2NL 1 0.01 0 0.2
40 INT45933 PKN1 Regulation of PKN3 1 0.05 0 0.2
41 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
42 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
43 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
44 INT119561 TLE4 Negative_regulation of Positive_regulation of CD1D 1 0.00 0.68 0.16
45 INT119557 CD1D Positive_regulation of IL4 1 0.00 0.67 0.16
46 INT119558 CD1D Positive_regulation of TNF 1 0.00 0.67 0.15
47 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
48 INT182480 Binding of Cd1d1 and Cxcr6 1 0.27 0.25 0.15
49 INT119563 CD1D Positive_regulation of IL5 1 0.01 0.67 0.15
50 INT339116 CNA1 Regulation of RSF1 1 0.00 0.3 0.13
51 INT220639 Binding of Apbb1 and Ighd 1 0.12 0.31 0.12
52 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
53 INT188358 Binding of Csf2 and Positive_regulation of Jak2 1 0.34 0.19 0.11
54 INT169340 Binding of UGT8 and Jak2 1 0.36 0.15 0.11
55 INT328413 Binding of Snca and Nlrp1a 1 0.06 0.75 0.1
56 INT213421 Binding of CXCL2 and SET 1 0.11 0.17 0.1
57 INT213417 Binding of CCL7 and SET 1 0.11 0.17 0.1
58 INT213414 Binding of CXCL1 and SET 1 0.10 0.17 0.1
59 INT213415 Binding of CCL8 and SET 1 0.11 0.17 0.1
60 INT213420 Binding of IL6 and SET 1 0.10 0.17 0.1
61 INT213416 Binding of CCL2 and SET 1 0.11 0.17 0.1
62 INT243652 Gk Negative_regulation of Gene_expression of Il12a 1 0.01 0 0.09
63 INT289539 Negative_regulation of Sirt1 Negative_regulation of Gene_expression of Agrp 1 0.29 0.47 0.09
64 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
65 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
66 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
67 INT289603 Sirt1 Negative_regulation of Localization of PPARG 1 0.02 0.43 0.08
68 INT310113 Binding of SET and TP53INP2 1 0.15 0.05 0.08
69 INT289540 Sirt1 Negative_regulation of Localization of Ins1 1 0.03 0.43 0.08
70 INT273374 Binding of JAK2 and STAT3 1 0.24 0 0.07
71 INT273368 Negative_regulation of Binding of JAK2 and STAT3 1 0.28 0 0.07
72 INT289533 Sirt1 Negative_regulation of Pparg 1 0.18 0.42 0.07
73 INT256160 Positive_regulation of Binding of Pgc and Sirt1 1 0.55 0.21 0.07
74 INT289602 Sirt1 Negative_regulation of PPARG 1 0.02 0.37 0.07
75 INT256161 Binding of Pgc and Sirt1 1 0.38 0.21 0.07
76 INT242480 Ciapin1 Positive_regulation of Gene_expression of Jak2 1 0.27 1.05 0.07
77 INT273371 JAK2 Regulation of Protein_catabolism of SOCS1 1 0.01 0 0.06
78 INT200807 Jak2 Positive_regulation of Mvd 1 0.18 3.46 0.06
79 INT325769 Binding of EPOR and Positive_regulation of Phosphorylation of JAK2 1 0.66 0 0.06
80 INT273365 JAK2 Regulation of SOCS1 1 0.01 0 0.06
81 INT310110 SET Positive_regulation of Localization of POMT1 1 0.08 0 0.05
82 INT238117 Positive_regulation of STAT3 Positive_regulation of Gene_expression of JAK2 1 0.11 0 0.05
83 INT238116 STAT3 Positive_regulation of Gene_expression of JAK2 1 0.16 0 0.05
84 INT340293 Binding of Ins1 and Sirt1 1 0.25 1.25 0.05
85 INT180348 CYP2A6 Regulation of AIRE 1 0.01 2.01 0.05
86 INT354715 Binding of PKN1 and Pick1 1 0.01 0.19 0.04
87 INT354682 Binding of ASIC1 and PKN1 1 0.01 0.19 0.04
88 INT210466 Negative_regulation of Binding of Gopc and Uhrf2 1 0.10 0.07 0.04
89 INT210465 Binding of Gopc and Uhrf2 1 0.09 0.07 0.04
90 INT289541 Sirt1 Regulation of Gene_expression of Agrp 1 0.41 0.52 0.04
91 INT274715 TBL1XR1 Positive_regulation of TIMP1 1 0.00 0.26 0.04
92 INT200821 Binding of Jak2 and Mvd 1 0.14 0.68 0.04
93 INT289538 Sirt1 Positive_regulation of Stat3 1 0.34 0.37 0.04
94 INT200813 Jak2 Positive_regulation of Akt1 1 0.26 1.46 0.03
95 INT253578 Csnk2a2 Negative_regulation of Jak2 1 0.09 0 0.03
96 INT253573 Binding of Jak2 and Pik3r1 1 0.06 0 0.03
97 INT200816 Jak2 Positive_regulation of Binding of Mvd 1 0.19 1.51 0.03
98 INT289101 Binding of KCNA1 and LEF1 1 0.00 2.58 0.03
99 INT175946 RSF1 Positive_regulation of Positive_regulation of CASP3 1 0.01 0.41 0.03
100 INT200810 Jak2 Positive_regulation of Src 1 0.29 1.46 0.03
101 INT289542 Sirt1 Negative_regulation of Stat3 1 0.32 0.31 0.03
102 INT249597 Jak2 Positive_regulation of Phosphorylation of Stat1 1 0.20 0.13 0.03
103 INT253575 Binding of Jak2 and Pik3r2 1 0.00 0 0.03
104 INT289526 Binding of Arc and Sirt1 1 0.08 0.55 0.03
105 INT200815 Binding of Epo and Jak2 1 0.36 0.98 0.03
106 INT289599 Sirt1 Positive_regulation of Ppargc1a 1 0.51 0.36 0.03
107 INT200822 Akt1 Regulation of Jak2 1 0.25 1.48 0.03
108 INT260342 Binding of Esr1 and Rcc1 1 0.05 0.99 0
109 INT180040 Binding of D7Cwr3P and Sirt1 1 0.00 0 0
110 INT300696 Sirt1 Regulation of Cyb5r3 1 0.03 0 0
111 INT356117 Binding of SORL1 and Apbb1 1 0.14 0.43 0
112 INT340502 Agtr1a Negative_regulation of Phosphorylation of Jak2 1 0.12 2.32 0
113 INT253366 Il6 Positive_regulation of Phosphorylation of Jak2 1 0.31 0.2 0
114 INT299444 Foxl2 Positive_regulation of Sirt1 1 0.24 0.31 0
115 INT289600 Negative_regulation of Binding of Sirt1 and Sirt1 1 0.47 1.17 0
116 INT299458 Gene_expression of Sirt1 Negative_regulation of Foxl2 1 0.25 0.32 0
117 INT222868 Binding of Chuk and Pkn1 1 0.00 0 0
118 INT337402 LEF1 Positive_regulation of E2F1 1 0.11 0 0
119 INT317313 Atp13a2 Negative_regulation of Snca 1 0.13 0.59 0
120 INT204325 Binding of PPARGC1A and SIRT1 1 0.39 0.19 0
121 INT166237 NLRP1 Positive_regulation of Localization of CD1D 1 0.48 0 0
122 INT339096 Ezh2 Regulation of Rcc1 1 0.02 1.1 0
123 INT201541 Binding of NPC1 and BRD7 1 0.35 1.59 0
124 INT183648 Binding of Lef1 and Ctnnd2 1 0.07 1.05 0
125 INT337415 Negative_regulation of MIR203 Positive_regulation of Positive_regulation of LEF1 1 0.03 0.25 0
126 INT289534 Sirt1 Regulation of Regulation of Pomc 1 0.04 0.15 0
127 INT200819 Epo Positive_regulation of Gene_expression of Jak2 1 0.49 0.91 0
128 INT215243 Binding of Rab3a and Noc2l 1 0.00 0.26 0
129 INT337405 MIR203 Regulation of LEF1 1 0.02 0.31 0
130 INT256165 Binding of Sirt6 and Sirt1 1 0.13 0.58 0
131 INT332136 POGLUT1 Negative_regulation of HJURP 1 0.00 0.06 0
132 INT337411 Negative_regulation of MIR203 Positive_regulation of Gene_expression of LEF1 1 0.04 0.25 0
133 INT318218 SIRT1 Positive_regulation of Binding of FOXO3 1 0.44 0.51 0
134 INT356100 Binding of Apbb1 and App 1 0.14 0.43 0
135 INT289518 Arc Regulation of Sirt1 1 0.10 0.56 0
136 INT274716 TBL1XR1 Positive_regulation of Gene_expression of MMP1 1 0.02 0.45 0
137 INT300081 Binding of JAK2 and TYK2 1 0.09 1.13 0
138 INT289537 Lep Negative_regulation of Sirt1 1 0.20 0.05 0
139 INT318219 SIRT1 Regulation of TBK1 1 0.03 0.43 0
140 INT185453 Binding of PRKCB and Lhx1 1 0.35 1.99 0
141 INT310115 Binding of NOVA2 and SET 1 0.12 0 0
142 INT289102 KCNA1 Negative_regulation of Gene_expression of LEF1 1 0.00 0.44 0
143 INT289098 KCNA1 Regulation of LEF1 1 0.00 0.67 0
144 INT289517 Sirt1 Regulation of Prkag1 1 0.02 0.08 0
145 INT253630 Binding of HNRNPA1 and Npm1 1 0.00 0.19 0
146 INT204326 SIRT1 Positive_regulation of PPARGC1A 1 0.51 0.19 0
147 INT318221 SIRT1 Positive_regulation of FOXO3 1 0.41 0.63 0
148 INT350503 Binding of HSP90AA1 and JAK2 1 0.06 1.39 0
149 INT317315 Gene_expression of Snca Negative_regulation of Psmb10 1 0.00 0.52 0
150 INT317320 Binding of Snca and Atp13a2 1 0.08 0.58 0
151 INT337637 SIRT1 Negative_regulation of TP53 1 0.23 1.49 0
152 INT289598 Binding of Sirt1 and Sirt1 1 0.41 1.15 0
153 INT337417 MIR203 Negative_regulation of LEF1 1 0.04 0.57 0
154 INT312304 Binding of JAK2 and VEGFA 1 0.30 0.82 0
155 INT220822 Binding of Myc and LEF1 1 0.26 0.08 0
156 INT300303 Binding of Gk and Foxo3 1 0.09 1.53 0
157 INT327872 Binding of Postn and Pkn1 1 0.03 0.21 0
158 INT298105 Ca2 Negative_regulation of Cd1d1 1 0.12 0.09 0
159 INT300307 Binding of Tp53 and Sirt1 1 0.24 0.98 0
160 INT289519 Sirt1 Regulation of Rps6kb1 1 0.25 0.13 0
161 INT220766 Binding of MAX and LEF1 1 0.40 0.08 0
162 INT289530 Sirt1 Regulation of Foxo1 1 0.25 0.42 0
163 INT289523 Binding of Foxo1 and Positive_regulation of Sirt1 1 0.36 0.13 0
164 INT204321 NOS3 Regulation of SIRT1 1 0.23 0.1 0
165 INT314132 Sirt1 Positive_regulation of Ppargc1a 1 0.50 2.3 0
166 INT299451 Foxl2 Negative_regulation of Gene_expression of Sirt1 1 0.25 0.32 0
167 INT289531 Acsm3 Positive_regulation of Sirt1 1 0.01 0.27 0
168 INT241535 Abl1 Regulation of Positive_regulation of Jak2 1 0.10 0.53 0
169 INT215242 Binding of Rab27a and Noc2l 1 0.07 0.26 0
170 INT318683 ARPP21 Negative_regulation of SET 1 0.00 0.1 0
171 INT318216 SIRT1 Positive_regulation of Gene_expression of FOXO3 1 0.36 0.52 0
172 INT318217 SIRT1 Regulation of TP53 1 0.07 0.43 0
173 INT198026 JAK2 Positive_regulation of HCC 1 0.19 1.35 0
174 INT350505 Negative_regulation of Binding of HSP90AA1 and JAK2 1 0.07 1.5 0
175 INT331090 Binding of Ctsl and Itga2 1 0.10 0.2 0
176 INT289100 KCNA1 Regulation of Gene_expression of LEF1 1 0.00 0.68 0
177 INT198928 Binding of Apbb1 and Lrp8 1 0.07 0.17 0
178 INT204319 SIRT1 Regulation of Gene_expression of PPARGC1A 1 0.50 0.12 0
179 INT289535 Negative_regulation of Sirt1 Negative_regulation of Binding of Foxo1 1 0.29 0.14 0
180 INT350504 ABL1 Negative_regulation of JAK2 1 0.20 2.18 0
181 INT289529 Lep Regulation of Sirt1 1 0.28 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for histone binding. They are ordered first by their pain relevance and then by number of times they were reported in histone binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
2 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
3 INT47301 Gene_expression of Ctsl 27 0.76 7.72 9.32
4 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
5 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
6 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
7 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
8 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
9 INT47298 Localization of Ctsl 13 0.79 3.77 4.08
10 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
11 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
12 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
13 INT174117 Gene_expression of Cd1d1 26 0.75 12.07 3.07
14 INT123595 Regulation of Snca 7 0.62 4.3 3.06
15 INT40128 Binding of Noc2l 7 0.27 0.67 3.03
16 INT82719 Positive_regulation of ASF1A 2 0.08 9.55 3
17 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
18 INT113339 Binding of JAK2 6 0.40 5.31 2.4
19 INT26696 Gene_expression of Hils1 4 0.21 1.18 2.38
20 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
21 INT156694 Binding of SET 10 0.36 3.77 2.21
22 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
23 INT13368 Binding of Hils1 5 0.23 0.46 2.14
24 INT94628 Gene_expression of CD1D 12 0.75 5.58 2.13
25 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
26 INT156720 Localization of CD1D 7 0.68 1.1 2.09
27 INT47303 Regulation of Ctsl 10 0.56 2.64 2.04
28 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
29 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
30 INT184410 Gene_expression of ASF1A 6 0.11 5.51 1.94
31 INT48850 Gene_expression of PKN1 16 0.52 1.93 1.92
32 INT58208 Negative_regulation of Ctsl 8 0.53 3.49 1.91
33 INT127125 Localization of Snca 6 0.81 8.24 1.88
34 INT106153 Gene_expression of HJURP 5 0.04 2.33 1.85
35 INT47302 Regulation of Gene_expression of Ctsl 2 0.53 0.54 1.77
36 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
37 INT127145 Gene_expression of SET 46 0.65 10.39 1.7
38 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
39 INT210455 Gene_expression of Noc2l 3 0.33 1.01 1.58
40 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
41 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
42 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
43 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
44 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
45 INT201271 Phosphorylation of Snca 3 0.82 4.22 1.45
46 INT168863 Regulation of Wdtc1 3 0.08 1.88 1.45
47 INT124247 Negative_regulation of Gene_expression of Snca 12 0.59 3.87 1.39
48 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
49 INT100275 Gene_expression of TBL1XR1 19 0.25 6.99 1.33
50 INT58761 Regulation of CD1D 3 0.26 1.54 1.33
51 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
52 INT41698 Localization of Hils1 3 0.16 0.54 1.29
53 INT56385 Positive_regulation of Gk 11 0.22 15.07 1.28
54 INT18947 Negative_regulation of Hils1 3 0.04 1.11 1.27
55 INT314186 Gene_expression of Npm1 1 0.01 1.78 1.22
56 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19
57 INT23415 Regulation of Hils1 2 0.27 0.29 1.18
58 INT47305 Positive_regulation of Gene_expression of Ctsl 5 0.59 2.06 1.12
59 INT151753 Transcription of Snca 6 0.69 1.99 1.11
60 INT292945 Positive_regulation of Positive_regulation of Snca 4 0.69 2.42 1.05
61 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04
62 INT223563 Gene_expression of Uhrf2 4 0.48 1.15 1.04
63 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
64 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
65 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
66 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96
67 INT137807 Binding of Cd1d1 4 0.31 1.26 0.94
68 INT6534 Negative_regulation of Ctsl1 3 0.54 0.11 0.94
69 INT169336 Binding of Jak2 2 0.42 1.31 0.93
70 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
71 INT151752 Positive_regulation of Transcription of Snca 2 0.50 0.99 0.92
72 INT351587 Positive_regulation of Gene_expression of Uhrf2 1 0.29 0.81 0.92
73 INT124246 Binding of Snca 10 0.37 6.53 0.9
74 INT36494 Positive_regulation of Hils1 2 0.15 0.88 0.88
75 INT184027 Phosphorylation of Jak2 6 0.82 2.58 0.87
76 INT51790 Negative_regulation of ASF1A 2 0.17 2.73 0.86
77 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
78 INT24860 Positive_regulation of CD1D 6 0.49 2.13 0.83
79 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
80 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81
81 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
82 INT120046 Negative_regulation of Localization of Ctsl 2 0.40 0.31 0.8
83 INT237408 Positive_regulation of Positive_regulation of Jak2 1 0.28 1.56 0.79
84 INT48851 Positive_regulation of Gene_expression of PKN1 2 0.27 0.67 0.78
85 INT113342 Positive_regulation of Phosphorylation of JAK2 2 0.66 2.58 0.72
86 INT179481 Positive_regulation of Wdtc1 8 0.67 7.11 0.71
87 INT40069 Negative_regulation of Binding of Hils1 1 0.03 0.09 0.67
88 INT26695 Positive_regulation of Binding of Hils1 2 0.11 0.2 0.66
89 INT274725 Regulation of TBL1XR1 5 0.11 2.08 0.64
90 INT139186 Positive_regulation of APBB1 1 0.00 0.31 0.62
91 INT114405 Regulation of Pkn1 1 0.44 1.58 0.61
92 INT28687 Gene_expression of Ctsl1 4 0.61 0.48 0.57
93 INT132104 Positive_regulation of Gene_expression of CD1D 2 0.03 0.55 0.57
94 INT51843 Localization of Ctsl1 3 0.62 0.54 0.54
95 INT184417 Positive_regulation of Positive_regulation of ASF1A 1 0.08 1.25 0.54
96 INT160148 Positive_regulation of Ctsl 2 0.43 0.74 0.52
97 INT172310 Positive_regulation of PKN1 6 0.12 2 0.51
98 INT184411 Negative_regulation of Positive_regulation of ASF1A 1 0.05 1.46 0.51
99 INT315427 Positive_regulation of Uhrf2 2 0.38 0.33 0.5
100 INT289580 Negative_regulation of Sirt1 23 0.58 9.03 0.48
101 INT182468 Positive_regulation of Cd1d1 5 0.61 4.08 0.48
102 INT175960 Positive_regulation of RSF1 4 0.50 3.88 0.48
103 INT184414 Localization of ASF1A 1 0.08 1.01 0.48
104 INT184062 Binding of Jak2 5 0.37 3.13 0.47
105 INT216519 Gene_expression of Wdtc1 4 0.65 4.02 0.47
106 INT24859 Negative_regulation of CD1D 2 0.58 0.41 0.47
107 INT274724 Positive_regulation of TBL1XR1 5 0.12 2.74 0.45
108 INT6533 Binding of Ctsl1 2 0.34 0 0.45
109 INT300291 Phosphorylation of Sirt1 1 0.77 6.07 0.45
110 INT205890 Transcription of Jak2 1 0.41 0.22 0.43
111 INT47895 Localization of Gk 3 0.22 2.35 0.42
112 INT240935 Transcription of Sirt1 2 0.68 0.42 0.42
113 INT343940 Binding of Uhrf2 2 0.30 0.06 0.42
114 INT148264 Transcription of SNCA 1 0.40 0.25 0.42
115 INT340290 Regulation of Transcription of Sirt1 1 0.43 0.13 0.42
116 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41
117 INT216873 Binding of TBL1XR1 3 0.36 4.44 0.4
118 INT107462 Localization of Jak2 2 0.60 0.78 0.4
119 INT174118 Regulation of Gene_expression of Cd1d1 1 0.44 1.42 0.4
120 INT348083 Positive_regulation of Ctsl1 1 0.08 0.21 0.4
121 INT229697 Negative_regulation of Phosphorylation of Jak2 1 0.15 0.54 0.39
122 INT314185 Localization of Npm1 1 0.02 0.44 0.39
123 INT343972 Negative_regulation of Binding of SNCA 1 0.36 0.2 0.39
124 INT255571 Gene_expression of Gk 15 0.26 15.42 0.38
125 INT224637 Protein_catabolism of Ctsl 1 0.12 0.76 0.37
126 INT169628 Binding of SNCA 4 0.47 3.53 0.36
127 INT200786 Positive_regulation of Gene_expression of Jak2 9 0.69 6.03 0.35
128 INT205910 Negative_regulation of Positive_regulation of Jak2 1 0.33 0.26 0.35
129 INT240914 Negative_regulation of Sirt1 9 0.46 3.16 0.34
130 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
131 INT19783 Localization of Wdtc1 2 0.13 1.89 0.33
132 INT314188 Regulation of Npm1 1 0.01 0.33 0.33
133 INT222639 Gene_expression of Cd1d1 2 0.65 0.65 0.32
134 INT289546 Negative_regulation of Gene_expression of Sirt1 5 0.42 3.1 0.31
135 INT204368 Gene_expression of SIRT1 17 0.76 4.48 0.3
136 INT66060 Regulation of Gene_expression of PKN1 1 0.23 0 0.3
137 INT343973 Localization of SNCA 1 0.63 0.07 0.3
138 INT92859 Positive_regulation of Positive_regulation of Hils1 1 0.03 0 0.3
139 INT6536 Negative_regulation of Binding of Ctsl1 1 0.39 0 0.3
140 INT182465 Negative_regulation of Cd1d1 4 0.28 1.72 0.29
141 INT315428 Transcription of Uhrf2 1 0.38 0 0.28
142 INT156707 Positive_regulation of SET 6 0.49 1.14 0.26
143 INT274742 Localization of TBL1XR1 2 0.24 1.4 0.26
144 INT287251 Negative_regulation of PKN1 6 0.01 1.86 0.25
145 INT100277 Positive_regulation of Gene_expression of TBL1XR1 5 0.19 1.9 0.25
146 INT303972 Positive_regulation of Gene_expression of JAK2 2 0.63 1.3 0.24
147 INT220582 Binding of Apbb1 2 0.14 0.69 0.24
148 INT66230 Negative_regulation of Rcc1 1 0.28 0.75 0.24
149 INT174116 Negative_regulation of Gene_expression of Cd1d1 1 0.31 0.51 0.24
150 INT139053 Phosphorylation of PRKCB 1 0.04 0.32 0.23
151 INT139051 Positive_regulation of Phosphorylation of PRKCB 1 0.02 0.33 0.23
152 INT184412 Positive_regulation of Gene_expression of ASF1A 1 0.06 1.01 0.23
153 INT139054 Negative_regulation of Phosphorylation of PRKCB 1 0.02 0.33 0.23
154 INT142052 Binding of Snca 4 0.47 1.02 0.22
155 INT36060 Protein_catabolism of Ctsl1 2 0.83 0.15 0.22
156 INT124178 Regulation of Ctsl1 1 0.23 0.19 0.22
157 INT182453 Positive_regulation of Gene_expression of Cd1d1 6 0.67 1.64 0.21
158 INT260340 Gene_expression of Rcc1 4 0.58 5.36 0.21
159 INT220862 Negative_regulation of Transcription of Ctsl 1 0.05 0.41 0.21
160 INT292944 Regulation of Positive_regulation of Snca 1 0.45 0.36 0.21
161 INT220859 Transcription of Ctsl 1 0.09 0.41 0.21
162 INT289551 Regulation of Sirt1 8 0.61 4.46 0.2
163 INT41699 Positive_regulation of Localization of Hils1 1 0.11 0 0.2
164 INT132107 Positive_regulation of Positive_regulation of CD1D 1 0.04 0.16 0.2
165 INT170886 Gene_expression of AIRE 2 0.49 4.63 0.19
166 INT144005 Negative_regulation of PRKCB 2 0.28 0.2 0.19
167 INT257418 Negative_regulation of Transcription of Snca 1 0.43 0.93 0.19
168 INT233130 Regulation of PKN1 2 0.02 0.69 0.18
169 INT248768 Localization of SET 3 0.44 2.38 0.17
170 INT246620 Negative_regulation of Positive_regulation of Sirt1 2 0.39 1.9 0.17
171 INT328811 Negative_regulation of Localization of Jak2 1 0.34 0.13 0.17
172 INT166361 Phosphorylation of SNCA 1 0.70 0.72 0.17
173 INT200802 Regulation of Jak2 5 0.61 2.86 0.16
174 INT315429 Regulation of Uhrf2 1 0.32 0 0.16
175 INT157084 Localization of Snca 1 0.51 0.17 0.16
176 INT343974 Negative_regulation of Gene_expression of SNCA 1 0.31 0.09 0.16
177 INT300298 Phosphorylation of Gk 1 0.24 5.15 0.15
178 INT260339 Positive_regulation of Gene_expression of Rcc1 1 0.11 2.28 0.15
179 INT319289 Protein_catabolism of Snca 1 0.35 0.93 0.15
180 INT47304 Regulation of Localization of Ctsl 1 0.23 0.14 0.15
181 INT286343 Negative_regulation of Gene_expression of Snca 1 0.26 0.65 0.15
182 INT287249 Localization of PKN1 3 0.03 0.78 0.14
183 INT256111 Regulation of Gene_expression of Sirt1 1 0.32 0.73 0.14
184 INT348081 Positive_regulation of Gene_expression of Ctsl1 1 0.06 0.24 0.14
185 INT47300 Negative_regulation of Gene_expression of Ctsl 1 0.57 0.14 0.14
186 INT204365 Positive_regulation of Gene_expression of SIRT1 8 0.68 2.9 0.13
187 INT255570 Binding of Gk 4 0.11 4.73 0.13
188 INT175956 Gene_expression of RSF1 3 0.49 0.94 0.13
189 INT155154 Binding of CD1D 2 0.36 1.7 0.12
190 INT47299 Positive_regulation of Localization of Ctsl 1 0.40 0.15 0.12
191 INT255568 Positive_regulation of Gene_expression of Gk 4 0.17 8.23 0.11
192 INT289543 Regulation of Gene_expression of Sirt1 3 0.45 1.81 0.11
193 INT289547 Positive_regulation of Positive_regulation of Sirt1 2 0.69 0.76 0.11
194 INT278143 Positive_regulation of Negative_regulation of Jak2 1 0.16 0.54 0.11
195 INT332681 Regulation of Positive_regulation of Sirt1 1 0.16 0.69 0.11
196 INT36061 Negative_regulation of Protein_catabolism of Ctsl1 1 0.12 0.08 0.1
197 INT312354 Regulation of Gene_expression of JAK2 1 0.25 1.17 0.1
198 INT144004 Positive_regulation of PRKCB 1 0.45 0 0.1
199 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09
200 INT133407 Binding of APBB1 2 0.35 1.63 0.09
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