GO:0042416

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Name dopamine biosynthetic process
Categary Process
Go Slim No
Go Link GO:0042416
Unique Molecular Interactions 268
Total Molecular Interactions 461
Total Single Events 4779
Pain Genes Associated 21

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for dopamine biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for dopamine biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6
2 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19
3 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
4 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
5 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64
6 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
7 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76
8 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67
9 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65
10 INT172206 Binding of Slc6a3 and ADHD1 2 0.03 2.76 1.61
11 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61
12 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54
13 INT40887 Penk Regulation of Th 1 0.04 0 1.53
14 INT100908 Slc6a3 Regulation of Positive_regulation of Etf1 1 0.05 0 1.41
15 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 0.13 0.15 1.36
16 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
17 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
18 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
19 INT119713 Negative_regulation of Slc6a3 Positive_regulation of Cpu3 1 0.39 0.71 1.26
20 INT184919 Binding of da and Slc6a3 1 0.12 0.33 1.23
21 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
22 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
23 INT90644 Slc6a3 Positive_regulation of Th 1 0.51 0 1.2
24 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
25 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
26 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
27 INT76256 Binding of Slc6a3 and Sigmar1 1 0.20 0 1.16
28 INT336559 SLC6A3 Positive_regulation of GOPC 1 0.08 1 1.15
29 INT106069 TH Positive_regulation of Th 1 0.07 0.16 1.14
30 INT321476 Binding of Slc6a3 and Slc6a2 1 0.01 0.41 1.14
31 INT321473 Binding of Slc6a3 and Ubqln1 1 0.00 0.41 1.13
32 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1
33 INT44838 Pitpnm1 Negative_regulation of Th 1 0.02 0 1.09
34 INT31547 Binding of Th and Vip 1 0.31 0 1.08
35 INT221 Chd7 Negative_regulation of Th 1 0.02 0 1.04
36 INT41175 Adra2a Regulation of Th 1 0.59 0 1.04
37 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
38 INT131173 Chrna7 Positive_regulation of Localization of Abat 1 0.10 0 1.01
39 INT31548 Binding of Th and Dbh 1 0.35 0 0.98
40 INT60827 Ddc Positive_regulation of Localization of Abat 1 0.12 0.34 0.94
41 INT60828 Ddc Positive_regulation of Abat 1 0.13 0.34 0.93
42 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
43 INT184916 Binding of da and Th 1 0.09 1.22 0.87
44 INT272039 Ddc Positive_regulation of Gene_expression of Aanat 1 0.00 0.26 0.87
45 INT122687 Binding of Galr2 and Th 1 0.13 0.07 0.83
46 INT122688 Binding of Galr1 and Th 1 0.14 0.07 0.83
47 INT122686 Binding of Galr3 and Th 1 0.14 0.07 0.83
48 INT214370 Slc6a3 Regulation of Amph 1 0.14 0.44 0.82
49 INT63940 Negative_regulation of Vta1 Positive_regulation of Th 1 0.13 0 0.81
50 INT184918 da Positive_regulation of Negative_regulation of Th 1 0.14 0.14 0.77
51 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
52 INT23681 Negative_regulation of Binding of Stx3 and Chrna7 1 0.00 0 0.75
53 INT23680 Binding of Stx3 and Chrna7 1 0.00 0 0.75
54 INT147278 Negative_regulation of Calca Positive_regulation of Th 1 0.41 0.76 0.74
55 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
56 INT147277 Calca Positive_regulation of Th 1 0.48 0.76 0.74
57 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
58 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72
59 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
60 INT210144 Binding of Slc6a3 and Slc37a4 1 0.11 0.23 0.72
61 INT144367 Gdnf Negative_regulation of Positive_regulation of Th 1 0.11 0.77 0.7
62 INT99937 Ddc Regulation of Transcription of Qrfp 1 0.02 0 0.69
63 INT326586 SLC18A2 Negative_regulation of DDC 1 0.28 0.91 0.66
64 INT50634 Ddc Regulation of Gene_expression of Glul 1 0.02 0 0.65
65 INT313435 Syp Regulation of Th 1 0.43 1.6 0.64
66 INT7958 LOC686180 Positive_regulation of Gene_expression of Th 1 0.02 0 0.64
67 INT127057 Ddc Positive_regulation of Gene_expression of Slc1a2 1 0.01 0.06 0.63
68 INT113146 Ddc Positive_regulation of Gene_expression of Nr4a1 1 0.06 0.1 0.63
69 INT127056 Ddc Positive_regulation of Transcription of Drd3 1 0.10 0.06 0.63
70 INT148257 NR4A2 Regulation of Gene_expression of SLC6A3 1 0.60 0.4 0.59
71 INT336557 SLC6A3 Positive_regulation of Binding of GOPC 1 0.08 0.5 0.58
72 INT270935 Cpe Regulation of Phosphorylation of Slc6a3 1 0.31 0 0.57
73 INT23679 Chrna7 Regulation of Binding of Stx3 1 0.00 0 0.56
74 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54
75 INT56733 Ddc Positive_regulation of Localization of GLUL 1 0.00 0 0.54
76 INT228852 Th Positive_regulation of Vta1 1 0.04 0 0.53
77 INT270984 Slc6a3 Regulation of IGKC 1 0.02 0 0.53
78 INT228851 Th Positive_regulation of Mtf2 1 0.02 0 0.52
79 INT184922 Negative_regulation of Th Negative_regulation of da 1 0.12 0.18 0.52
80 INT270937 Cpe Regulation of Slc6a3 1 0.36 0 0.5
81 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5
82 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48
83 INT7957 Calca Positive_regulation of Gene_expression of Th 1 0.39 0 0.47
84 INT72089 TGFB2 Positive_regulation of POMC 1 0.11 0 0.46
85 INT184877 Negative_regulation of Binding of Slc6a3 and ADHD1 1 0.01 0.69 0.45
86 INT83111 LIAS Negative_regulation of Binding of Chrna7 1 0.02 0 0.45
87 INT90642 Cpe Negative_regulation of Negative_regulation of Slc6a3 1 0.04 0 0.44
88 INT249021 Gabrg1 Negative_regulation of Th 1 0.08 0.06 0.44
89 INT157451 Binding of Slc6a3 and Dbh 1 0.04 0.48 0.44
90 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
91 INT121837 Sct Positive_regulation of Th 1 0.23 0.06 0.43
92 INT344104 Binding of Slc6a3 and Obfc1 1 0.00 0 0.43
93 INT139487 Oprm1 Positive_regulation of Th 1 0.26 0.1 0.42
94 INT147280 Binding of Pecam1 and Th 1 0.29 0.41 0.41
95 INT302871 Negative_regulation of Adora2a Positive_regulation of Phosphorylation of Th 1 0.26 0.12 0.4
96 INT7625 Man2a2 Regulation of Th 1 0.01 0.07 0.4
97 INT31794 Hps6 Positive_regulation of Th 1 0.03 0 0.38
98 INT64639 Slc1a1 Positive_regulation of Ddc 1 0.30 0.3 0.38
99 INT50635 Ddc Regulation of Gene_expression of Penk 1 0.03 0 0.38
100 INT281155 Binding of ITIH4 and Ddc 1 0.09 1.27 0.37
101 INT190003 Binding of MVD and Slc6a3 1 0.13 0.19 0.37
102 INT270939 Gene_expression of Cpe Positive_regulation of Slc6a3 1 0.20 0 0.36
103 INT214374 Pik3cb Regulation of Gene_expression of Slc6a3 1 0.37 0.3 0.35
104 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
105 INT102341 Binding of Slc6a3 and Flvcr2 2 0.06 0 0.34
106 INT127887 SLC6A3 Regulation of Drd2 1 0.34 0.68 0.34
107 INT173476 Th Regulation of Gene_expression of Bcar1 1 0.10 0 0.34
108 INT34855 Negative_regulation of Maoa Negative_regulation of Th 1 0.17 0 0.34
109 INT102340 Binding of Slc6a3 and Sert1 1 0.18 0 0.34
110 INT173478 Th Regulation of Localization of Ins1 1 0.13 0 0.34
111 INT46788 Chrna7 Positive_regulation of G6pd 1 0.50 0 0.33
112 INT326587 GYPA Regulation of DDC 1 0.08 0.83 0.33
113 INT153019 nct Positive_regulation of Transcription of Th 1 0.19 0.61 0.32
114 INT153020 nct Positive_regulation of Gene_expression of Th 1 0.19 0.61 0.32
115 INT126097 Ddc Positive_regulation of Egr1 1 0.08 0 0.32
116 INT290614 Binding of Th and RLS 1 0.21 3.26 0.31
117 INT1757 DDC Regulation of Localization of GH1 1 0.01 0 0.31
118 INT90643 Negative_regulation of Slc6a3 Positive_regulation of Th 1 0.47 0 0.3
119 INT55404 Binding of ENG and Th 1 0.02 0 0.3
120 INT99599 ZNF398 Negative_regulation of NR4A2 1 0.05 0.41 0.3
121 INT99600 ZNF398 Negative_regulation of Transcription of NR4A2 1 0.10 0.41 0.3
122 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
123 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
124 INT314484 TH Positive_regulation of RLS 1 0.01 1.66 0.29
125 INT59682 Hps6 Positive_regulation of Binding of Chrna7 1 0.02 0 0.29
126 INT270954 Gene_expression of Cpe Positive_regulation of Gene_expression of Slc6a3 1 0.23 0 0.28
127 INT78484 Binding of DBH and TH 1 0.09 0 0.28
128 INT353979 Ddc Positive_regulation of Pet1 1 0.49 0 0.26
129 INT59683 Binding of Chrna7 and Evi2a 1 0.03 0 0.25
130 INT270955 Cpe Regulation of Gene_expression of Slc6a3 1 0.14 0 0.25
131 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
132 INT270951 Regulation of Binding of Slc6a3 and Cpe 1 0.23 0 0.25
133 INT325767 Negative_regulation of Omd Positive_regulation of Ddc 1 0.01 0.38 0.25
134 INT214366 Ins1 Regulation of Slc6a3 1 0.11 0.09 0.25
135 INT143972 Chrna7 Negative_regulation of Gene_expression of Trpv1 1 0.01 0.18 0.24
136 INT138088 Ddc Regulation of Transcription of Nr4a1 1 0.02 0.16 0.24
137 INT336561 Binding of DDC and DIO2 1 0.04 0.27 0.24
138 INT329432 Binding of CCR6 and TH 1 0.00 0.47 0.23
139 INT329431 Binding of CCL20 and TH 1 0.00 0.47 0.23
140 INT164 Ddc Negative_regulation of Prl 1 0.06 0 0.23
141 INT270940 Negative_regulation of Binding of Slc6a3 and Cpe 1 0.25 0 0.23
142 INT149973 MC1R Positive_regulation of Gene_expression of NR4A2 1 0.44 0.32 0.23
143 INT270948 Cpe Regulation of Regulation of Slc6a3 1 0.14 0.28 0.23
144 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21
145 INT143974 Chrna7 Positive_regulation of Vti1b 1 0.17 0.16 0.2
146 INT201440 Negative_regulation of Ngf Positive_regulation of Slc6a3 1 0.10 0 0.2
147 INT270947 Cpe Negative_regulation of Phosphorylation of Slc6a3 1 0.25 0 0.2
148 INT61987 Th Regulation of Penk 1 0.46 0 0.2
149 INT300562 Binding of Slc6a3 and Datd 1 0.02 1.12 0.2
150 INT201443 Ngf Positive_regulation of Slc6a3 1 0.11 0 0.19
151 INT184868 Binding of Slc6a3 and Lmo1 1 0.02 0.72 0.19
152 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19
153 INT349504 Ptpn2 Negative_regulation of Th 1 0.23 2 0.19
154 INT47426 Chrna7 Positive_regulation of Localization of Ldha 1 0.05 0 0.18
155 INT342744 Ddc Regulation of Trh 1 0.02 0.37 0.18
156 INT47427 Chrna7 Positive_regulation of Ldha 1 0.05 0 0.18
157 INT313453 Siglec1 Regulation of Th 1 0.02 0.61 0.17
158 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
159 INT88450 Uncx Regulation of Gene_expression of Th 1 0.06 0 0.17
160 INT101725 Binding of ITGA4 and Chrna7 1 0.00 0 0.16
161 INT349505 Ptpn2 Negative_regulation of Slc6a3 1 0.19 0.7 0.16
162 INT157097 Ddc Positive_regulation of Drd3 1 0.30 0.88 0.16
163 INT349503 Ptpn2 Negative_regulation of Gene_expression of Th 1 0.23 0.7 0.16
164 INT340111 Chrna7 Regulation of CYSLTR1 1 0.00 0.25 0.15
165 INT99084 Ddc Positive_regulation of Pdyn 2 0.15 0.87 0.14
166 INT261456 Sftpd Positive_regulation of Gene_expression of Th 1 0.10 0.77 0.13
167 INT313441 Th Regulation of Siglec1 1 0.02 0.22 0.13
168 INT313439 Syp Negative_regulation of Th 1 0.30 0.14 0.13
169 INT197317 Nr4a2 Regulation of Gene_expression of Th 1 0.03 0.07 0.12
170 INT258761 Binding of Slc6a3 and ADHD1 1 0.03 0.51 0.12
171 INT99085 Ddc Positive_regulation of Transcription of Pdyn 1 0.15 0.31 0.11
172 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
173 INT313454 Negative_regulation of Syp Negative_regulation of Th 1 0.30 0.14 0.1
174 INT328413 Binding of Snca and Nlrp1a 1 0.06 0.75 0.1
175 INT149178 IL4 Negative_regulation of Positive_regulation of TGFB2 1 0.15 0.29 0.1
176 INT184920 Binding of Agtrap and Slc6a3 1 0.02 0.09 0.09
177 INT341776 ESR1 Positive_regulation of Gene_expression of SLC6A3 1 0.06 0.08 0.09
178 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
179 INT313442 Th Regulation of Phosphorylation of Syp 1 0.32 0 0.08
180 INT201446 GOPC Positive_regulation of Slc6a3 1 0.03 0.07 0.08
181 INT313459 Gene_expression of Syp Negative_regulation of Th 1 0.30 0.49 0.08
182 INT313437 Th Regulation of Phosphorylation of Siglec1 1 0.04 0 0.08
183 INT171709 Rac1 Negative_regulation of Localization of Chrna7 1 0.04 0.75 0.08
184 INT125208 Pou4f1 Negative_regulation of Gene_expression of Th 1 0.28 0.67 0.07
185 INT125209 Pou4f1 Positive_regulation of Gene_expression of Th 1 0.33 0.67 0.07
186 INT184917 Slc6a3 Positive_regulation of Agtrap 1 0.03 0.08 0.06
187 INT313450 Th Regulation of Syp 1 0.32 0.6 0.06
188 INT201439 Dlat Regulation of Localization of Slc6a3 1 0.04 0 0.06
189 INT242618 Binding of Slc18a3 and Th 1 0.13 0.26 0.05
190 INT321651 Binding of Slc6a3 and Uts2r 1 0.04 0.06 0.05
191 INT321652 Binding of Slc6a3 and Slc6a4 1 0.26 0.07 0.05
192 INT180373 CYP2A6 Regulation of Cyp2d4 1 0.05 2.01 0.05
193 INT201445 ESR1 Regulation of Slc6a3 1 0.02 0.05 0.04
194 INT352062 Binding of SV2A and Chrna7 1 0.00 0.7 0.04
195 INT325766 Binding of Ddc and Omd 1 0.01 0.59 0.04
196 INT105726 Ddc Positive_regulation of Gene_expression of Pdyn 1 0.04 0.62 0.04
197 INT201442 Dlat Regulation of Slc6a3 1 0.04 0.18 0.04
198 INT270950 Binding of Slc6a3 and Tgfb1i1 1 0.02 0.23 0.04
199 INT313433 53T Regulation of Th 1 0.00 0 0.03
200 INT281125 Binding of Ddc and Cd4 1 0.09 0.37 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for dopamine biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in dopamine biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
2 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
3 INT7327 Regulation of Th 164 0.62 29.67 110.14
4 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
5 INT350 Localization of Th 79 0.80 10.26 41.17
6 INT30817 Gene_expression of Th 142 0.76 33.56 38.12
7 INT81037 Negative_regulation of Slc6a3 70 0.59 15.31 37.01
8 INT23330 Binding of Chrna7 79 0.48 10.06 35.5
9 INT7326 Transcription of Th 83 0.72 13.5 35.33
10 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
11 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
12 INT67 Negative_regulation of Ddc 66 0.59 15.34 28.96
13 INT93360 Gene_expression of Slc6a3 63 0.78 19.54 26.55
14 INT80791 Gene_expression of Slc6a3 113 0.78 11.89 25.76
15 INT4781 Gene_expression of TH 68 0.73 26.92 24.01
16 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78
17 INT61825 Negative_regulation of Slc6a3 47 0.59 6.52 21.27
18 INT13643 Phosphorylation of Th 20 0.82 1.9 20.97
19 INT6230 Localization of Ddc 40 0.79 13.11 20.88
20 INT24240 Positive_regulation of Th 60 0.70 9.92 20.18
21 INT68347 Negative_regulation of Cyp2d4 34 0.58 7.62 18.35
22 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53
23 INT219 Negative_regulation of Th 55 0.59 20.88 17.09
24 INT65214 Binding of Slc6a3 54 0.48 4.77 16.79
25 INT24241 Phosphorylation of Th 35 0.81 8.69 16.06
26 INT13716 Positive_regulation of TH 33 0.68 19.11 16
27 INT54356 Regulation of Slc6a3 48 0.58 5.86 15.24
28 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23
29 INT109264 Positive_regulation of Transcription of Th 17 0.50 4.73 14.33
30 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
31 INT31368 Positive_regulation of Positive_regulation of Th 19 0.51 2.2 12.68
32 INT28458 Localization of Slc6a3 31 0.76 2.33 12.49
33 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41
34 INT141 Binding of Th 21 0.48 3.53 11.04
35 INT78567 Positive_regulation of Gene_expression of Th 25 0.68 5.32 10.75
36 INT93967 Binding of Slc6a3 22 0.48 6.81 10.74
37 INT23675 Negative_regulation of Binding of Chrna7 18 0.37 0.5 10.74
38 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69
39 INT90639 Positive_regulation of Slc6a3 25 0.61 10.95 10.41
40 INT9027 Positive_regulation of Ddc 24 0.66 6.04 10.19
41 INT139443 Positive_regulation of GCH1 9 0.69 8.2 10.14
42 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
43 INT48496 Regulation of Transcription of Th 16 0.54 2.29 10.02
44 INT53062 Gene_expression of Ddc 31 0.77 11.59 9.63
45 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51
46 INT220 Negative_regulation of Ddc 16 0.59 2.94 8.66
47 INT146343 Regulation of Slc6a3 17 0.60 7.33 8.27
48 INT28461 Positive_regulation of Localization of Slc6a3 8 0.41 0 8.24
49 INT109265 Transcription of Th 18 0.68 4.5 8.21
50 INT184845 Negative_regulation of Gene_expression of Slc6a3 13 0.59 3.25 7.79
51 INT28457 Positive_regulation of Slc6a3 26 0.50 3.64 7.76
52 INT26643 Negative_regulation of Positive_regulation of Th 12 0.59 1.26 7.74
53 INT47811 Positive_regulation of Localization of Ddc 11 0.69 4 7.6
54 INT152347 Binding of GCH1 8 0.37 6.13 7.36
55 INT4284 Regulation of Ddc 17 0.43 8.17 7.31
56 INT7624 Positive_regulation of Regulation of Th 7 0.50 2.41 7
57 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88
58 INT109266 Negative_regulation of Transcription of Th 9 0.42 2.5 6.85
59 INT66987 Regulation of Th 23 0.61 7.86 6.8
60 INT3506 Localization of TH 12 0.81 0.78 6.66
61 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42
62 INT7569 Positive_regulation of Transcription of Th 19 0.70 2.6 6.17
63 INT163776 Regulation of GCH1 7 0.27 4.58 6.16
64 INT30317 Regulation of TH 14 0.43 7.27 5.38
65 INT23952 Gene_expression of Cyp2d4 18 0.78 4.76 5.31
66 INT144735 Gene_expression of DDC 8 0.75 3.21 5.31
67 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25
68 INT230829 Localization of Cyp2d4 3 0.63 0.61 5.18
69 INT7623 Regulation of Regulation of Th 11 0.44 1.31 5.16
70 INT25831 Gene_expression of NR4A2 20 0.74 2.73 4.92
71 INT24236 Positive_regulation of Phosphorylation of Th 12 0.61 3.68 4.87
72 INT37151 Localization of Th 13 0.57 3.11 4.82
73 INT40620 Regulation of Positive_regulation of Th 9 0.45 2.45 4.69
74 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
75 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
76 INT60188 Positive_regulation of Cyp2d4 10 0.70 1.04 4.35
77 INT30165 Positive_regulation of Phosphorylation of Th 8 0.56 0.75 4.22
78 INT201438 Phosphorylation of Slc6a3 3 0.68 0.79 4.19
79 INT183479 Positive_regulation of Gene_expression of Slc6a3 16 0.57 0.91 4.13
80 INT180338 Binding of Cyp2d4 12 0.47 6.87 4.09
81 INT119053 Positive_regulation of SLC6A3 15 0.65 2.51 4
82 INT4649 Positive_regulation of Chrna7 17 0.50 5.48 3.92
83 INT77823 Negative_regulation of Negative_regulation of Th 9 0.59 1.56 3.79
84 INT214362 Negative_regulation of Gene_expression of Slc6a3 7 0.41 1.58 3.67
85 INT146342 Negative_regulation of Negative_regulation of Slc6a3 5 0.44 3.34 3.4
86 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
87 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
88 INT30166 Regulation of Phosphorylation of Th 4 0.50 0.52 3.33
89 INT135815 Transcription of Gch1 1 0.60 0 3.32
90 INT102901 Regulation of Gene_expression of Th 12 0.60 2.42 3.22
91 INT122577 Regulation of SLC6A3 9 0.53 1.47 3.09
92 INT149795 Gene_expression of Ddc 8 0.73 1.5 3.06
93 INT123595 Regulation of Snca 7 0.62 4.3 3.06
94 INT167547 Positive_regulation of Gene_expression of Slc6a3 8 0.46 3.33 3.03
95 INT54355 Transcription of Slc6a3 6 0.61 0.28 3.02
96 INT4782 Positive_regulation of Gene_expression of TH 12 0.47 7.36 2.95
97 INT28460 Negative_regulation of Localization of Slc6a3 5 0.36 0.24 2.9
98 INT47812 Negative_regulation of Localization of Ddc 5 0.51 1.99 2.8
99 INT150933 Negative_regulation of Positive_regulation of GCH1 3 0.58 1.8 2.77
100 INT16406 Positive_regulation of Negative_regulation of Ddc 6 0.67 0.53 2.6
101 INT106066 Negative_regulation of Positive_regulation of TH 1 0.18 0.22 2.6
102 INT106068 Positive_regulation of Positive_regulation of TH 1 0.21 0.22 2.59
103 INT150932 Positive_regulation of Gene_expression of GCH1 3 0.70 2.07 2.57
104 INT4704 Positive_regulation of Negative_regulation of Th 4 0.50 0.06 2.56
105 INT13644 Negative_regulation of Phosphorylation of Th 2 0.43 0.06 2.51
106 INT229111 Localization of SLC6A3 5 0.68 1.12 2.48
107 INT184914 Negative_regulation of Gene_expression of Th 15 0.43 9.17 2.46
108 INT50723 Positive_regulation of Nr4a2 7 0.53 0.47 2.46
109 INT99607 Transcription of NR4A2 2 0.68 1.61 2.41
110 INT180343 Negative_regulation of Negative_regulation of Cyp2d4 2 0.36 0.49 2.38
111 INT15210 Negative_regulation of Transcription of Th 9 0.59 0.47 2.37
112 INT283973 Transcription of GCH1 1 0.61 1.99 2.33
113 INT111584 Positive_regulation of Negative_regulation of Slc6a3 4 0.47 0.68 2.31
114 INT283975 Negative_regulation of Localization of GCH1 1 0.38 1.99 2.27
115 INT135827 Positive_regulation of Transcription of Gch1 1 0.58 0 2.2
116 INT15209 Negative_regulation of Regulation of Th 6 0.51 1.64 2.16
117 INT24196 Positive_regulation of Binding of Chrna7 8 0.45 0.79 2.13
118 INT93965 Negative_regulation of Binding of Slc6a3 5 0.42 1.39 2.07
119 INT169552 Positive_regulation of Negative_regulation of Slc6a3 3 0.50 0.51 2.05
120 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
121 INT14360 Positive_regulation of DDC 7 0.70 2.97 2.02
122 INT258637 Regulation of Gene_expression of GCH1 1 0.62 1.77 2.02
123 INT157095 Binding of Ddc 5 0.27 4.6 2
124 INT243846 Localization of DDC 3 0.63 0.66 1.99
125 INT95461 Positive_regulation of Regulation of Slc6a3 3 0.47 0 1.95
126 INT1834 Positive_regulation of Binding of Th 1 0.46 0 1.91
127 INT127125 Localization of Snca 6 0.81 8.24 1.88
128 INT135820 Regulation of Gch1 1 0.59 0 1.88
129 INT47425 Localization of Chrna7 11 0.81 6.7 1.86
130 INT314510 Protein_catabolism of TH 1 0.10 3.28 1.86
131 INT77990 Protein_catabolism of Slc6a3 6 0.72 0.99 1.84
132 INT210140 Regulation of Gene_expression of Slc6a3 1 0.62 0.83 1.82
133 INT3505 Binding of TH 5 0.39 2.6 1.8
134 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
135 INT81169 Localization of Nr4a2 1 0.68 0 1.71
136 INT145545 Transcription of TH 3 0.67 1.48 1.64
137 INT169387 Regulation of Gene_expression of Chrna7 4 0.36 2.19 1.63
138 INT198952 Localization of Slc6a3 3 0.75 0.68 1.62
139 INT50724 Positive_regulation of Positive_regulation of Nr4a2 2 0.49 0.17 1.58
140 INT167847 Positive_regulation of Gene_expression of Chrna7 7 0.49 3.02 1.57
141 INT53008 Gene_expression of Nr4a2 25 0.74 4.89 1.5
142 INT114808 Positive_regulation of Binding of SLC6A3 4 0.50 0.63 1.45
143 INT201271 Phosphorylation of Snca 3 0.82 4.22 1.45
144 INT82676 Negative_regulation of Gene_expression of Ddc 4 0.55 0.55 1.43
145 INT124247 Negative_regulation of Gene_expression of Snca 12 0.59 3.87 1.39
146 INT28456 Negative_regulation of Positive_regulation of Slc6a3 2 0.32 0 1.38
147 INT135822 Gene_expression of Gch1 2 0.50 0.77 1.35
148 INT333291 Positive_regulation of Gene_expression of DDC 1 0.49 0.13 1.35
149 INT99930 Positive_regulation of Gene_expression of SLC6A3 4 0.43 0.08 1.34
150 INT121136 Negative_regulation of DDC 4 0.57 2.98 1.32
151 INT229116 Negative_regulation of Localization of SLC6A3 1 0.22 0.17 1.31
152 INT4480 Positive_regulation of Ddc 3 0.39 0.53 1.3
153 INT148262 Negative_regulation of Gene_expression of SLC6A3 2 0.38 1.66 1.29
154 INT102200 Gene_expression of Nr4a2 9 0.72 3.69 1.28
155 INT138347 Phosphorylation of Slc6a3 2 0.71 1.01 1.26
156 INT97869 Negative_regulation of Positive_regulation of Th 3 0.25 0.79 1.23
157 INT156390 Regulation of Gene_expression of Slc6a3 2 0.37 0.28 1.22
158 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19
159 INT145488 Regulation of Cyp2d4 5 0.45 1.1 1.19
160 INT28459 Regulation of Positive_regulation of Slc6a3 1 0.34 0 1.17
161 INT122891 Negative_regulation of Gch1 4 0.16 1.83 1.15
162 INT26760 Negative_regulation of Localization of Th 2 0.40 0.09 1.14
163 INT24197 Regulation of Binding of Chrna7 2 0.11 0 1.14
164 INT283974 Negative_regulation of Transcription of GCH1 1 0.38 0.99 1.13
165 INT283972 Localization of GCH1 1 0.67 0.99 1.13
166 INT283976 Positive_regulation of Binding of GCH1 1 0.45 1.27 1.13
167 INT50267 Negative_regulation of Negative_regulation of Th 3 0.42 1.57 1.12
168 INT89670 Negative_regulation of Binding of Th 2 0.43 0.28 1.12
169 INT151753 Transcription of Snca 6 0.69 1.99 1.11
170 INT150931 Negative_regulation of GCH1 6 0.59 1.23 1.05
171 INT292945 Positive_regulation of Positive_regulation of Snca 4 0.69 2.42 1.05
172 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
173 INT152000 Regulation of Regulation of Slc6a3 1 0.44 0.68 0.99
174 INT81878 Gene_expression of TGFB2 3 0.42 2.02 0.97
175 INT133215 Transcription of Slc6a3 4 0.67 1.59 0.95
176 INT208792 Negative_regulation of Gene_expression of TH 6 0.35 1.11 0.94
177 INT93969 Positive_regulation of Binding of Slc6a3 1 0.41 0.62 0.94
178 INT198953 Regulation of Regulation of Th 1 0.01 0.1 0.93
179 INT138346 Positive_regulation of Phosphorylation of Slc6a3 1 0.17 1.24 0.93
180 INT151752 Positive_regulation of Transcription of Snca 2 0.50 0.99 0.92
181 INT148259 Negative_regulation of Gene_expression of NR4A2 2 0.55 0.71 0.91
182 INT124246 Binding of Snca 10 0.37 6.53 0.9
183 INT24242 Negative_regulation of Phosphorylation of Th 3 0.38 1.44 0.9
184 INT208789 Negative_regulation of Localization of TH 2 0.25 0 0.89
185 INT50266 Regulation of Negative_regulation of Th 1 0.42 0.94 0.88
186 INT53309 Regulation of Localization of Th 1 0.39 0 0.84
187 INT148263 Transcription of SLC6A3 1 0.62 0.49 0.81
188 INT86036 Negative_regulation of Positive_regulation of Ddc 2 0.35 0.42 0.8
189 INT210141 Positive_regulation of Localization of Slc6a3 1 0.50 0.35 0.8
190 INT270962 Negative_regulation of Phosphorylation of Slc6a3 1 0.42 0 0.8
191 INT93737 Gene_expression of Tgfb2 2 0.03 1.16 0.77
192 INT93736 Positive_regulation of Gene_expression of Tgfb2 2 0.02 1.16 0.77
193 INT122578 Regulation of Gene_expression of SLC6A3 3 0.34 0.2 0.75
194 INT54354 Regulation of Transcription of Slc6a3 1 0.21 0.08 0.74
195 INT148261 Negative_regulation of Transcription of NR4A2 1 0.41 0.31 0.72
196 INT87728 Regulation of Gene_expression of Ddc 4 0.25 1.1 0.71
197 INT201436 Positive_regulation of Phosphorylation of Slc6a3 2 0.50 0.27 0.71
198 INT90714 Positive_regulation of Nr4a2 1 0.67 0.97 0.71
199 INT146344 Negative_regulation of Regulation of Slc6a3 2 0.32 1.17 0.7
200 INT258710 Regulation of Negative_regulation of Ddc 2 0.25 1.28 0.66
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