GO:0042417

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Name dopamine metabolic process
Categary Process
Go Slim No
Go Link GO:0042417
Unique Molecular Interactions 329
Total Molecular Interactions 452
Total Single Events 4417
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for dopamine metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for dopamine metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
2 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
3 INT111758 Binding of Drd2 and Insrr 1 0.01 0.94 4.33
4 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
5 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
6 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
7 INT111757 Positive_regulation of Binding of Drd2 and Insrr 1 0.02 0.64 2.89
8 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
9 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57
10 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
11 INT33756 Akr1d1 Positive_regulation of Npr1 3 0.01 0 2.05
12 INT21261 Penk Negative_regulation of Npr1 1 0.02 0 2
13 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
14 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
15 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
16 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
17 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66
18 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
19 INT33757 Hmmr Positive_regulation of Npr1 1 0.01 0 1.59
20 INT172203 Binding of Comt and Maoa 1 0.31 0.98 1.43
21 INT111759 Binding of Cpe and Drd2 1 0.01 0.32 1.42
22 INT111762 Positive_regulation of Binding of Cpe and Drd2 1 0.02 0.33 1.42
23 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
24 INT6466 Binding of Npr1 and Oprd1 1 0.01 0 1.37
25 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3
26 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29
27 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
28 INT143620 Ltp Positive_regulation of Npr1 1 0.01 0.16 1.26
29 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
30 INT42554 Oprl1 Regulation of Npr1 2 0.06 0 1.22
31 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
32 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
33 INT261617 SNRNP70 Regulation of Comt 1 0.01 0.4 1.18
34 INT13205 Oprd1 Negative_regulation of Npr1 2 0.01 0 1.16
35 INT209132 Binding of Drd2 and Riok3 1 0.01 1.57 1.16
36 INT13204 Binding of Npr1 and Akr1d1 1 0.00 0 1.14
37 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
38 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
39 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
40 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
41 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
42 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
43 INT33142 Pck1 Positive_regulation of Npr1 4 0.01 0.5 1.02
44 INT13502 Penk Positive_regulation of Npr1 1 0.02 0.19 1.01
45 INT13503 Regulation of Penk Positive_regulation of Npr1 1 0.02 0.19 1.01
46 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
47 INT21332 Binding of Drd2 and Gm5195 1 0.01 0.26 1
48 INT170449 Pax3 Positive_regulation of Spr 1 0.01 0.26 0.99
49 INT42555 Oprl1 Negative_regulation of Npr1 1 0.02 0 0.99
50 INT60827 Ddc Positive_regulation of Localization of Abat 1 0.12 0.34 0.94
51 INT60828 Ddc Positive_regulation of Abat 1 0.13 0.34 0.93
52 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
53 INT108647 Binding of Grin2a and Camk1d 1 0.33 0.78 0.9
54 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86
55 INT311612 Binding of Drd2 and Sert1 1 0.12 0.65 0.86
56 INT111790 Penk Regulation of Gene_expression of Npr1 1 0.22 0.56 0.86
57 INT36008 Negative_regulation of Binding of Drd2 and Prl 1 0.01 2.11 0.85
58 INT41156 Sst Negative_regulation of Npr1 1 0.05 0 0.84
59 INT29781 PDYN Negative_regulation of Npr1 1 0.00 0.22 0.84
60 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 0.32 1.26 0.84
61 INT340115 Comt Regulation of Localization of Dusp1 1 0.12 0.83 0.83
62 INT340114 Comt Regulation of Localization of Pain1 1 0.02 0.83 0.83
63 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
64 INT340113 Comt Regulation of Bdnf 1 0.21 0.74 0.82
65 INT164364 Binding of DRD2 and SUGT1 2 0.06 0.33 0.77
66 INT298457 Binding of Calca and Npr1 1 0.01 0.39 0.77
67 INT334833 Binding of Drd2 and Ncs1 1 0.05 1.11 0.76
68 INT151339 Positive_regulation of Binding of Drd2 and P9Ehs1 1 0.11 0.22 0.76
69 INT21260 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.05 0 0.76
70 INT151340 Binding of Drd2 and P9Ehs1 1 0.09 0.22 0.75
71 INT147619 Npr1 Positive_regulation of Localization of Calca 1 0.03 0 0.75
72 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74
73 INT57658 ASNA1 Positive_regulation of Npr1 1 0.00 0.15 0.74
74 INT327702 Binding of Comt and Drd2 1 0.28 0.27 0.74
75 INT327712 Binding of Comt and Rbm39 1 0.00 0.27 0.74
76 INT287132 Binding of NT5E and Comt 1 0.03 0.11 0.73
77 INT296292 Binding of Car1 and Grin2a 1 0.14 0.32 0.72
78 INT296289 Grin2a Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
79 INT296288 Grin2a Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
80 INT169603 Nppb Regulation of Npr1 1 0.26 0.95 0.69
81 INT99937 Ddc Regulation of Transcription of Qrfp 1 0.02 0 0.69
82 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68
83 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
84 INT50634 Ddc Regulation of Gene_expression of Glul 1 0.02 0 0.65
85 INT6464 Sst Regulation of Negative_regulation of Npr1 1 0.01 0 0.64
86 INT6463 Oprd1 Regulation of Negative_regulation of Npr1 1 0.01 0 0.63
87 INT6465 Trh Regulation of Negative_regulation of Npr1 1 0.01 0 0.63
88 INT127057 Ddc Positive_regulation of Gene_expression of Slc1a2 1 0.01 0.06 0.63
89 INT113146 Ddc Positive_regulation of Gene_expression of Nr4a1 1 0.06 0.1 0.63
90 INT127056 Ddc Positive_regulation of Transcription of Drd3 1 0.10 0.06 0.63
91 INT209131 Binding of Bcl2a1a and Drd2 1 0.22 0.45 0.62
92 INT170446 Pax3 Positive_regulation of Gene_expression of Spr 1 0.01 0 0.58
93 INT112107 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2a 1 0.40 0.49 0.57
94 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
95 INT112106 Negative_regulation of Dlg2 Negative_regulation of Grin2a 1 0.40 0.48 0.56
96 INT45258 SLAMF6 Positive_regulation of Drd2 1 0.00 0 0.55
97 INT311524 Gnrhr Positive_regulation of Transcription of Grin2a 1 0.02 0.54 0.55
98 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55
99 INT271889 Binding of DRD2 and ANKK1 1 0.23 0.36 0.55
100 INT271888 Binding of DRD2 and DNAJC7 1 0.14 0.36 0.55
101 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54
102 INT251151 Binding of Grin2a and Dlg3 1 0.24 0.32 0.54
103 INT303653 Binding of DRD2 and SST 1 0.18 0.45 0.54
104 INT32908 Binding of ADCY1 and Drd2 1 0.00 0 0.54
105 INT56733 Ddc Positive_regulation of Localization of GLUL 1 0.00 0 0.54
106 INT25414 Positive_regulation of Drd2 Positive_regulation of Penk 1 0.38 0 0.53
107 INT165045 Drd2 Regulation of Cpe 1 0.07 0 0.52
108 INT165042 Drd2 Regulation of Tac1 1 0.22 0 0.52
109 INT165043 Drd2 Regulation of Cck 1 0.20 0 0.52
110 INT208121 Binding of Grin2a and Grin2b 3 0.35 0.06 0.51
111 INT20580 Drd2 Regulation of Akr1d1 1 0.02 0.26 0.51
112 INT184874 Drd1a Regulation of Gene_expression of Drd2 1 0.13 0.97 0.51
113 INT43075 Slc6a14 Regulation of Positive_regulation of Npr1 1 0.01 0 0.51
114 INT43076 Slc6a14 Regulation of Npr1 1 0.01 0 0.51
115 INT167455 Binding of MSD and Comt 1 0.15 0.28 0.5
116 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5
117 INT208122 Grin2a Positive_regulation of Positive_regulation of Ltp 1 0.16 0.21 0.49
118 INT250081 Grin2a Positive_regulation of Ltp 1 0.20 0.14 0.48
119 INT208120 Binding of Grin2a and Hpcal1 1 0.10 0.07 0.48
120 INT55265 Ptgdr Negative_regulation of Npr1 1 0.01 0 0.46
121 INT52679 Positive_regulation of Npr1 Positive_regulation of Positive_regulation of VSX1 1 0.00 0 0.45
122 INT127394 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin2a 1 0.01 0.71 0.45
123 INT127396 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin2a 1 0.00 0.71 0.45
124 INT16586 Binding of Drd2 and Nts 1 0.12 0 0.43
125 INT89666 Binding of Adora2a and Drd2 1 0.54 0.4 0.42
126 INT36009 Binding of Drd2 and Prl 1 0.01 1.05 0.42
127 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 0.22 0.09 0.41
128 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4
129 INT55588 Drd2 Regulation of Transcription of Gad1 1 0.15 0.07 0.4
130 INT131353 Binding of Npr1 and Nppb 1 0.27 1.73 0.4
131 INT131356 Binding of Nppa and Npr1 1 0.27 1.73 0.4
132 INT55589 Drd2 Regulation of Gad1 1 0.15 0.07 0.4
133 INT296301 Binding of Grin2a and Kcnip3 1 0.27 0 0.4
134 INT57649 Oprd1 Positive_regulation of Npr1 1 0.01 0.1 0.39
135 INT95999 Binding of Npr1 and Cnr1 1 0.05 0 0.39
136 INT64639 Slc1a1 Positive_regulation of Ddc 1 0.30 0.3 0.38
137 INT50635 Ddc Regulation of Gene_expression of Penk 1 0.03 0 0.38
138 INT334835 Negative_regulation of Binding of Drd2 and Ncs1 1 0.04 0.56 0.38
139 INT169604 Nppb Positive_regulation of Npr1 2 0.52 2.52 0.37
140 INT353391 Binding of DRD4 and GRB2 1 0.37 0.62 0.37
141 INT311616 Binding of MET and Comt 1 0.01 0.2 0.37
142 INT37247 Binding of Drd1a and Drd2 1 0.20 0 0.37
143 INT353392 Binding of DRD4 and NCK1 1 0.37 0.62 0.37
144 INT353390 Binding of DRD4 and SRC 1 0.25 0.62 0.37
145 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37
146 INT281155 Binding of ITIH4 and Ddc 1 0.09 1.27 0.37
147 INT250076 Grin2a Regulation of Positive_regulation of Ltp 1 0.10 0.06 0.35
148 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
149 INT127887 SLC6A3 Regulation of Drd2 1 0.34 0.68 0.34
150 INT51629 Binding of DRD3 and OPRK1 1 0.15 0 0.33
151 INT334836 Ncs1 Regulation of Drd2 1 0.02 0.48 0.33
152 INT51628 Binding of ACHE and DRD3 1 0.15 0 0.33
153 INT51631 Binding of DRD3 and PENK 1 0.08 0 0.33
154 INT109894 Drd2 Positive_regulation of FOS 1 0.01 0 0.33
155 INT251148 Negative_regulation of Binding of Grin2a and Dlg2 1 0.37 0.45 0.32
156 INT126097 Ddc Positive_regulation of Egr1 1 0.08 0 0.32
157 INT213485 Lep Positive_regulation of Localization of Grin2a 1 0.19 0 0.31
158 INT115261 Gene_expression of Nos2 Positive_regulation of Positive_regulation of Npr1 1 0.05 0.67 0.31
159 INT327701 Comt Regulation of Npcd 1 0.01 0 0.29
160 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
161 INT327706 Comt Regulation of Gopc 1 0.10 0 0.29
162 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
163 INT96436 Binding of Npr1 and Oprl1 1 0.05 0 0.29
164 INT212289 Vsnl1 Negative_regulation of Grin2a 1 0.04 0.38 0.28
165 INT273130 Negative_regulation of Binding of Drd2 and Hp 1 0.05 0 0.28
166 INT273129 Binding of Drd2 and Hp 1 0.04 0 0.28
167 INT97594 Penk Regulation of Gene_expression of Drd2 1 0.15 0.1 0.28
168 INT208499 Positive_regulation of Nkx1-1 Positive_regulation of Npr1 1 0.00 0 0.27
169 INT263732 Binding of Grin2a and Neto1 1 0.41 0 0.27
170 INT216040 Binding of Comt and Prodh 1 0.30 1.71 0.26
171 INT149358 Binding of Oprm1 and Positive_regulation of Positive_regulation of Npr1 1 0.00 0.09 0.26
172 INT317510 Binding of Grin2a and Gnptab 1 0.00 0 0.26
173 INT105004 Binding of DRD3 and PDYN 1 0.23 0.49 0.26
174 INT47012 Regulation of Pck1 Positive_regulation of Npr1 1 0.01 0 0.26
175 INT258757 Binding of Drd2 and Rends1 1 0.00 1.26 0.25
176 INT325767 Negative_regulation of Omd Positive_regulation of Ddc 1 0.01 0.38 0.25
177 INT250075 Binding of Hpcal4 and Negative_regulation of Gene_expression of Grin2a 1 0.03 0 0.24
178 INT287131 Negative_regulation of Binding of NT5E and Comt 1 0.03 0.06 0.23
179 INT164 Ddc Negative_regulation of Prl 1 0.06 0 0.23
180 INT164136 Binding of DRD2 and Prl 1 0.09 0 0.22
181 INT131355 Npr1 Regulation of Nppb 1 0.39 0.88 0.22
182 INT131354 Npr1 Regulation of Nppa 1 0.40 0.88 0.22
183 INT164135 Binding of Drd2 and Prl 1 0.04 0 0.22
184 INT311527 Binding of Grin2a and Gria1 1 0.01 0 0.21
185 INT202252 COMT Regulation of DRD2 1 0.31 0 0.21
186 INT302712 Binding of Hprt and Hrh1 1 0.25 1.07 0.2
187 INT69254 Drd2 Regulation of Gene_expression of Pomc 1 0.01 0 0.2
188 INT25089 Glul Positive_regulation of Npr1 1 0.00 0 0.2
189 INT154355 Binding of Nppc and Npr1 1 0.19 0.43 0.18
190 INT342744 Ddc Regulation of Trh 1 0.02 0.37 0.18
191 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
192 INT29959 Ahsp Positive_regulation of Npr1 1 0.00 0.18 0.17
193 INT33141 Pck1 Regulation of Npr1 1 0.00 0.17 0.16
194 INT157097 Ddc Positive_regulation of Drd3 1 0.30 0.88 0.16
195 INT310595 Ros1 Positive_regulation of Npr1 1 0.03 0.84 0.16
196 INT251435 Gnat3 Positive_regulation of NPR1 1 0.22 0.2 0.15
197 INT327700 Binding of Comt and 4930579C15Rik 1 0.08 0 0.15
198 INT311526 Gria1 Regulation of Gene_expression of Grin2a 1 0.01 0.32 0.15
199 INT99084 Ddc Positive_regulation of Pdyn 2 0.15 0.87 0.14
200 INT224129 Binding of DRD2 and Adora2a 1 0.03 0.19 0.14

Single Events

The table below shows the top 100 pain related interactions that have been reported for dopamine metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in dopamine metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78
2 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11
3 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
4 INT16455 Gene_expression of Drd2 116 0.78 22.71 38.47
5 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37
6 INT13501 Binding of Drd2 65 0.48 23.76 35.6
7 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28
8 INT11087 Positive_regulation of Drd2 54 0.69 12.4 31.43
9 INT67 Negative_regulation of Ddc 66 0.59 15.34 28.96
10 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41
11 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13
12 INT12484 Binding of Drd2 45 0.48 15.17 24.72
13 INT7715 Regulation of Drd2 35 0.62 10.79 22.3
14 INT6230 Localization of Ddc 40 0.79 13.11 20.88
15 INT49774 Binding of DRD2 48 0.48 17.42 20.73
16 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39
17 INT7017 Regulation of Npr1 45 0.52 3.38 20.05
18 INT4260 Negative_regulation of Positive_regulation of Npr1 29 0.43 4.39 19.57
19 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
20 INT68347 Negative_regulation of Cyp2d4 34 0.58 7.62 18.35
21 INT6461 Gene_expression of Npr1 35 0.75 10.38 17.58
22 INT9299 Positive_regulation of Positive_regulation of Npr1 32 0.53 6.65 16.72
23 INT26729 Negative_regulation of Drd2 28 0.55 9.32 15.17
24 INT14647 Positive_regulation of Grin2a 26 0.67 4.69 14.8
25 INT8989 Binding of Npr1 25 0.36 5.52 14.58
26 INT5599 Regulation of Drd2 25 0.52 3.07 13.31
27 INT101119 Negative_regulation of Comt 19 0.58 8.77 13.09
28 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
29 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
30 INT520 Binding of Comt 24 0.48 8.98 12.21
31 INT100799 Negative_regulation of Grin2a 27 0.57 7.33 12.2
32 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
33 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8
34 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
35 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
36 INT64193 Regulation of Grin2a 19 0.54 2.98 10.31
37 INT9027 Positive_regulation of Ddc 24 0.66 6.04 10.19
38 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
39 INT13606 Negative_regulation of Negative_regulation of Npr1 13 0.40 1.21 10.01
40 INT53062 Gene_expression of Ddc 31 0.77 11.59 9.63
41 INT57039 Positive_regulation of Gene_expression of Drd2 16 0.50 1.98 9.48
42 INT17764 Negative_regulation of Drd2 17 0.42 4.63 9.46
43 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
44 INT13296 Transcription of Drd2 17 0.66 2.7 9.07
45 INT6682 Regulation of Gene_expression of Drd2 13 0.51 2.17 8.82
46 INT26487 Positive_regulation of Npr1 17 0.70 10.01 8.78
47 INT44537 Positive_regulation of Comt 7 0.69 2.62 7.78
48 INT18190 Regulation of DRD2 11 0.60 9.01 7.63
49 INT47811 Positive_regulation of Localization of Ddc 11 0.69 4 7.6
50 INT75063 Regulation of Gene_expression of Drd2 10 0.62 2.82 7.38
51 INT4284 Regulation of Ddc 17 0.43 8.17 7.31
52 INT101121 Regulation of Comt 19 0.53 10.66 7.22
53 INT73760 Transcription of Drd2 14 0.72 2.11 7.19
54 INT26489 Negative_regulation of Npr1 15 0.59 5.7 6.79
55 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55
56 INT24460 Localization of Drd2 12 0.73 2.96 6.46
57 INT6459 Regulation of Negative_regulation of Npr1 10 0.53 0.16 6.44
58 INT150825 Binding of Comt 13 0.42 6.65 6.42
59 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41
60 INT7021 Positive_regulation of Negative_regulation of Npr1 8 0.22 1.02 6.36
61 INT50712 Gene_expression of Comt 13 0.68 6.33 6.23
62 INT86772 Localization of Drd2 14 0.80 1.93 6.17
63 INT6195 Transcription of Npr1 9 0.69 3 5.94
64 INT103880 Positive_regulation of DRD2 9 0.67 5.57 5.93
65 INT170443 Gene_expression of Spr 1 0.12 0.07 5.88
66 INT6681 Positive_regulation of Gene_expression of Drd2 10 0.65 1.78 5.78
67 INT67693 Binding of Grin2a 9 0.38 1.74 5.68
68 INT7018 Positive_regulation of Gene_expression of Npr1 10 0.59 5.09 5.66
69 INT13706 Localization of Npr1 10 0.59 0.83 5.42
70 INT23952 Gene_expression of Cyp2d4 18 0.78 4.76 5.31
71 INT208108 Localization of Grin2a 19 0.70 1.5 5.22
72 INT32432 Positive_regulation of Binding of Drd2 7 0.67 2.72 5.19
73 INT2162 Regulation of Comt 13 0.60 2.9 5.18
74 INT230829 Localization of Cyp2d4 3 0.63 0.61 5.18
75 INT19549 Binding of Grin2a 12 0.45 1.24 5.09
76 INT135474 Negative_regulation of Gene_expression of Grin2a 7 0.39 6.94 4.89
77 INT111947 Positive_regulation of Gene_expression of Grin2a 7 0.68 1.75 4.84
78 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78
79 INT2871 Positive_regulation of Comt 9 0.50 2.8 4.78
80 INT14125 Positive_regulation of Positive_regulation of Drd2 3 0.35 0.85 4.78
81 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
82 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
83 INT71676 Transcription of DRD2 5 0.69 1.19 4.47
84 INT36007 Negative_regulation of Binding of Drd2 7 0.57 3.22 4.36
85 INT60188 Positive_regulation of Cyp2d4 10 0.70 1.04 4.35
86 INT180338 Binding of Cyp2d4 12 0.47 6.87 4.09
87 INT172197 Positive_regulation of Gene_expression of Comt 12 0.69 7.61 4.06
88 INT103999 Positive_regulation of Phosphorylation of Grin2a 5 0.38 3.12 3.94
89 INT80473 Gene_expression of Spr 5 0.46 2.76 3.86
90 INT121986 Phosphorylation of Grin2a 5 0.76 0.83 3.71
91 INT172198 Protein_catabolism of Comt 7 0.88 2.78 3.6
92 INT206598 Regulation of Gene_expression of Comt 9 0.60 6 3.56
93 INT209221 Regulation of Gene_expression of Grin2a 5 0.24 2.81 3.45
94 INT195964 Transcription of Comt 8 0.71 4.72 3.4
95 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
96 INT102209 Negative_regulation of Gene_expression of Drd2 5 0.59 0.46 3.17
97 INT123595 Regulation of Snca 7 0.62 4.3 3.06
98 INT90611 Positive_regulation of Positive_regulation of Grin2a 4 0.63 1.89 3
99 INT101406 Regulation of Spr 3 0.25 1.32 2.95
100 INT82992 Gene_expression of DRD3 3 0.50 2.12 2.88
101 INT54449 Positive_regulation of Transcription of Npr1 3 0.45 1.73 2.81
102 INT47812 Negative_regulation of Localization of Ddc 5 0.51 1.99 2.8
103 INT99104 Gene_expression of Npr1 5 0.78 3.31 2.8
104 INT147412 Binding of DRD4 11 0.47 7.57 2.77
105 INT170439 Positive_regulation of Spr 1 0.10 0.3 2.67
106 INT189863 Gene_expression of DRD4 11 0.68 7.65 2.66
107 INT16406 Positive_regulation of Negative_regulation of Ddc 6 0.67 0.53 2.6
108 INT128983 Protein_catabolism of Comt 5 0.87 0.22 2.6
109 INT108468 Negative_regulation of Gene_expression of Drd2 3 0.41 0.67 2.58
110 INT105730 Localization of Grin2a 7 0.67 0.64 2.56
111 INT26205 Positive_regulation of Positive_regulation of NPR1 3 0.24 1.57 2.52
112 INT206593 Negative_regulation of Gene_expression of Comt 3 0.56 1.68 2.52
113 INT50723 Positive_regulation of Nr4a2 7 0.53 0.47 2.46
114 INT141075 Transcription of Grin2a 5 0.49 1.89 2.46
115 INT180343 Negative_regulation of Negative_regulation of Cyp2d4 2 0.36 0.49 2.38
116 INT11065 Gene_expression of NPR1 6 0.55 3.41 2.32
117 INT103881 Positive_regulation of Binding of DRD2 4 0.69 2.01 2.18
118 INT19804 Negative_regulation of Hprt 18 0.59 20.6 2.17
119 INT6460 Regulation of Gene_expression of Npr1 4 0.52 2.19 2.13
120 INT52865 Positive_regulation of Spr 2 0.49 0.56 2.06
121 INT105008 Binding of DRD3 5 0.36 3.15 2.05
122 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
123 INT157095 Binding of Ddc 5 0.27 4.6 2
124 INT25411 Positive_regulation of Positive_regulation of Drd2 2 0.48 0.5 1.98
125 INT74595 Regulation of Transcription of Grin2a 2 0.42 0.66 1.92
126 INT103624 Negative_regulation of Gene_expression of Grin2a 5 0.56 1.58 1.9
127 INT127125 Localization of Snca 6 0.81 8.24 1.88
128 INT447 Localization of Comt 4 0.75 0.76 1.8
129 INT151174 Negative_regulation of Transcription of Grin2a 3 0.40 0 1.8
130 INT14413 Regulation of Positive_regulation of Npr1 7 0.62 0.71 1.78
131 INT11098 Regulation of NPR1 5 0.37 1.39 1.74
132 INT81169 Localization of Nr4a2 1 0.68 0 1.71
133 INT267108 Negative_regulation of Gene_expression of DRD3 2 0.26 1.53 1.69
134 INT43045 Negative_regulation of Regulation of Npr1 3 0.12 0.17 1.65
135 INT80469 Negative_regulation of Spr 2 0.30 1.62 1.61
136 INT50724 Positive_regulation of Positive_regulation of Nr4a2 2 0.49 0.17 1.58
137 INT26488 Regulation of Npr1 4 0.39 0.88 1.56
138 INT101405 Binding of Spr 1 0.20 0.43 1.55
139 INT31921 Negative_regulation of Localization of Npr1 2 0.17 0 1.51
140 INT53008 Gene_expression of Nr4a2 25 0.74 4.89 1.5
141 INT6194 Regulation of Transcription of Npr1 2 0.05 0.08 1.46
142 INT201271 Phosphorylation of Snca 3 0.82 4.22 1.45
143 INT82676 Negative_regulation of Gene_expression of Ddc 4 0.55 0.55 1.43
144 INT75062 Regulation of Transcription of Drd2 1 0.51 0 1.41
145 INT67465 Positive_regulation of Regulation of Npr1 1 0.05 0.14 1.4
146 INT124247 Negative_regulation of Gene_expression of Snca 12 0.59 3.87 1.39
147 INT69498 Positive_regulation of DRD4 3 0.50 0.95 1.3
148 INT105729 Negative_regulation of Localization of Grin2a 3 0.38 0.08 1.29
149 INT102200 Gene_expression of Nr4a2 9 0.72 3.69 1.28
150 INT109272 Negative_regulation of Binding of DRD2 2 0.36 0.76 1.26
151 INT82991 Regulation of Gene_expression of DRD3 1 0.23 0.59 1.26
152 INT82988 Regulation of Transcription of DRD3 1 0.38 0.59 1.26
153 INT15663 Regulation of Transcription of Drd2 2 0.26 0.1 1.25
154 INT82987 Transcription of DRD3 1 0.58 0.59 1.25
155 INT78355 Negative_regulation of Gene_expression of Npr1 2 0.06 0.15 1.22
156 INT11099 Localization of NPR1 5 0.67 1.49 1.21
157 INT170440 Positive_regulation of Gene_expression of Spr 1 0.10 0 1.21
158 INT145488 Regulation of Cyp2d4 5 0.45 1.1 1.19
159 INT77216 Localization of DRD2 3 0.75 0 1.19
160 INT89756 Positive_regulation of Positive_regulation of Npr1 2 0.47 0.9 1.19
161 INT40170 Regulation of Localization of Npr1 2 0.05 0.12 1.16
162 INT80471 Negative_regulation of Gene_expression of Spr 1 0.22 1.19 1.16
163 INT81136 Binding of Npr1 6 0.48 1.45 1.15
164 INT65165 Positive_regulation of Negative_regulation of Comt 1 0.03 0 1.15
165 INT151753 Transcription of Snca 6 0.69 1.99 1.11
166 INT139647 Positive_regulation of Positive_regulation of Grin2a 2 0.44 0.38 1.11
167 INT292945 Positive_regulation of Positive_regulation of Snca 4 0.69 2.42 1.05
168 INT19803 Gene_expression of Hprt 15 0.67 4.81 1.03
169 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
170 INT202579 Regulation of Gene_expression of DRD2 4 0.41 1.11 0.99
171 INT82989 Regulation of DRD3 1 0.23 0.45 0.99
172 INT11100 Positive_regulation of Gene_expression of NPR1 2 0.37 1.49 0.98
173 INT19550 Positive_regulation of Binding of Grin2a 1 0.04 0 0.94
174 INT151752 Positive_regulation of Transcription of Snca 2 0.50 0.99 0.92
175 INT141076 Negative_regulation of Transcription of Grin2a 2 0.40 0.82 0.92
176 INT124246 Binding of Snca 10 0.37 6.53 0.9
177 INT195946 Gene_expression of Hprt1 9 0.75 1.03 0.89
178 INT11066 Negative_regulation of NPR1 5 0.27 0.89 0.88
179 INT101402 Positive_regulation of Gene_expression of Spr 1 0.27 0.26 0.88
180 INT101403 Transcription of Spr 1 0.29 0.26 0.88
181 INT101400 Positive_regulation of Transcription of Spr 1 0.25 0.26 0.88
182 INT282479 Regulation of Protein_catabolism of Comt 2 0.45 1.17 0.85
183 INT263688 Negative_regulation of Localization of Grin2a 2 0.31 0.16 0.84
184 INT11086 Regulation of Positive_regulation of Drd2 2 0.45 1.22 0.84
185 INT147867 Localization of Spr 1 0.65 1.16 0.84
186 INT42356 Negative_regulation of Binding of Npr1 1 0.32 0.37 0.82
187 INT32513 Regulation of Localization of NPR1 3 0.36 0.84 0.81
188 INT86036 Negative_regulation of Positive_regulation of Ddc 2 0.35 0.42 0.8
189 INT101404 Regulation of Gene_expression of Spr 1 0.34 0.28 0.8
190 INT13692 Negative_regulation of Positive_regulation of Drd2 1 0.01 0 0.79
191 INT103879 Regulation of Binding of DRD2 1 0.23 0.13 0.79
192 INT16434 Regulation of Positive_regulation of Drd2 1 0.30 0 0.78
193 INT195983 Localization of Comt 2 0.74 0.93 0.76
194 INT344931 Positive_regulation of Protein_catabolism of Comt 1 0.49 0 0.76
195 INT54452 Regulation of Regulation of Npr1 1 0.03 0 0.72
196 INT87728 Regulation of Gene_expression of Ddc 4 0.25 1.1 0.71
197 INT12885 Negative_regulation of Binding of Drd2 2 0.53 0.26 0.71
198 INT90714 Positive_regulation of Nr4a2 1 0.67 0.97 0.71
199 INT5569 Phosphorylation of Npr1 3 0.18 0.61 0.7
200 INT326603 Regulation of Positive_regulation of DRD2 1 0.44 0.8 0.69
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