GO:0042447

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Name hormone catabolic process
Categary Process
Go Slim No
Go Link GO:0042447
Unique Molecular Interactions 160
Total Molecular Interactions 203
Total Single Events 3224
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hormone catabolic process. They are ordered first by their pain relevance and then by number of times they were reported for hormone catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
2 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
3 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
4 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
5 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
6 INT24796 ACE Positive_regulation of Localization of HMMR 1 0.00 0.58 1.16
7 INT56500 Ide Regulation of Maoa 1 0.21 0 0.89
8 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75
9 INT77689 Binding of Ace and Tenc1 1 0.28 0.65 0.7
10 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
11 INT21607 ACE Positive_regulation of ANGPT2 1 0.03 0.13 0.61
12 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58
13 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
14 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
15 INT114067 Ace Regulation of Insr 1 0.09 0.31 0.39
16 INT229222 Negative_regulation of ACE Negative_regulation of Protein_catabolism of KNG1 1 0.06 0.53 0.37
17 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
18 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
19 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32
20 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
21 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3
22 INT246690 exf Regulation of Localization of Ide 1 0.00 0.17 0.3
23 INT230745 Negative_regulation of Ace Negative_regulation of Icam1 1 0.05 1.22 0.29
24 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
25 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28
26 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28
27 INT246689 Zglp1 Positive_regulation of Ide 1 0.06 0.28 0.27
28 INT246693 Zglp1 Positive_regulation of Localization of Ide 1 0.08 0.34 0.27
29 INT64726 Ace Negative_regulation of KNG1 1 0.01 0.26 0.25
30 INT64727 Ace Positive_regulation of KNG1 1 0.01 0.26 0.25
31 INT191500 ACE Positive_regulation of Localization of KNG1 1 0.10 0.17 0.24
32 INT239238 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.01 0.46 0.24
33 INT124078 Binding of Ace and Cpox 1 0.09 0.14 0.24
34 INT265828 ACE Regulation of Gene_expression of KNG1 1 0.32 0.83 0.22
35 INT200637 Binding of Abpa and Ace 1 0.01 4.62 0.22
36 INT246686 Ide Regulation of Ros1 1 0.03 0.41 0.22
37 INT265827 ACE Negative_regulation of ANGPT2 1 0.09 0.59 0.17
38 INT8164 Ace Positive_regulation of Gene_expression of Fos 1 0.24 0.32 0.16
39 INT258812 Sugt1 Positive_regulation of Ace 1 0.05 1.26 0.16
40 INT75058 Negative_regulation of ACE Negative_regulation of HHIP 1 0.25 0.43 0.15
41 INT307807 Ace Positive_regulation of ras 1 0.38 3 0.15
42 INT161797 Binding of ECE1 and ING1 1 0.01 0.68 0.14
43 INT324898 Ece1 Regulation of Gene_expression of Edn1 1 0.17 0.8 0.14
44 INT161795 Positive_regulation of Binding of ECE1 and ING1 1 0.02 0.68 0.14
45 INT161799 Positive_regulation of Binding of ECE1 and EDN1 1 0.07 0.68 0.14
46 INT344946 AGT Regulation of Negative_regulation of ACE 1 0.21 0.61 0.14
47 INT102885 Binding of ANG and ACE 2 0.17 0.37 0.13
48 INT256020 Ace Negative_regulation of Gene_expression of Agtr2 1 0.03 0.37 0.13
49 INT256021 Ace Negative_regulation of Gene_expression of Agtrap 1 0.05 0.37 0.13
50 INT354327 Gsk3b Positive_regulation of Gene_expression of Ide 1 0.17 0.33 0.13
51 INT329317 ACE Regulation of Positive_regulation of KNG1 1 0.02 1.05 0.12
52 INT329325 ACE Regulation of Negative_regulation of Agtr2 1 0.01 0.93 0.12
53 INT43095 Binding of Ace and Mme 1 0.26 0 0.12
54 INT229364 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.02 0.86 0.11
55 INT171162 Negative_regulation of Ace Negative_regulation of Gene_expression of Ccl2 1 0.02 1.18 0.1
56 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1
57 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09
58 INT104737 Ace Positive_regulation of Gene_expression of Ren1 1 0.35 0.09 0.09
59 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09
60 INT344945 Negative_regulation of ACE Positive_regulation of REN 1 0.23 0.64 0.09
61 INT312547 Akt1 Positive_regulation of Phosphorylation of Ide 1 0.01 0.6 0.08
62 INT307805 Ace Positive_regulation of Ang 1 0.32 1.52 0.07
63 INT324896 Ece1 Positive_regulation of Negative_regulation of Edn1 1 0.19 0.42 0.07
64 INT307806 Ace Positive_regulation of Agt 1 0.28 1.51 0.07
65 INT200641 Binding of ACE and Agtr1a 1 0.12 0.92 0.06
66 INT200638 Binding of ACE and Agtr2 1 0.10 0.93 0.06
67 INT246691 Ide Positive_regulation of Gene_expression of Nos3 1 0.03 0.26 0.05
68 INT200635 Binding of Ace and Spink1 1 0.37 1.4 0.05
69 INT29521 Ace Positive_regulation of ACE 1 0.19 0 0.04
70 INT283226 Binding of ACE and CC2D1A 1 0.11 2.37 0.04
71 INT191980 Ide Regulation of Sit1 1 0.17 0 0.04
72 INT104736 Ace Positive_regulation of Ren1 1 0.35 0 0.04
73 INT317393 Binding of Car2 and Ide 1 0.03 0.3 0
74 INT109818 Ace Regulation of ras 1 0.04 0.3 0
75 INT322250 Ace Regulation of Gene_expression of Agt 1 0.43 0.63 0
76 INT307804 Ace Positive_regulation of Gene_expression of Scrib 1 0.21 2.43 0
77 INT191982 Sit1 Regulation of Gene_expression of Ide 1 0.25 0.09 0
78 INT322240 Ace Regulation of Gene_expression of Htr2a 1 0.13 0.63 0
79 INT225536 Ncoa6 Positive_regulation of Localization of Ide 1 0.02 0.41 0
80 INT322239 Ace Regulation of Gene_expression of Agtrap 1 0.44 0.63 0
81 INT1181 Negative_regulation of Ace Positive_regulation of Ren 1 0.52 0.23 0
82 INT191981 Ide Positive_regulation of Positive_regulation of Sit1 1 0.28 0.06 0
83 INT191984 Ide Positive_regulation of Nppc 1 0.04 0.13 0
84 INT322253 Agt Regulation of Gene_expression of Ace 1 0.43 0.63 0
85 INT65004 Negative_regulation of Ace Positive_regulation of Agt 1 0.40 0 0
86 INT307808 Ace Positive_regulation of Gene_expression of Ace2 1 0.22 2.43 0
87 INT322238 Slc6a4 Regulation of Gene_expression of Ace 1 0.37 0.63 0
88 INT307210 Ide Positive_regulation of Ppara 1 0.02 0.18 0
89 INT322256 Ace Regulation of Gene_expression of Slc6a4 1 0.37 0.63 0
90 INT225582 Asc2 Positive_regulation of Localization of Ide 1 0.01 0.41 0
91 INT200488 Binding of ACE and SUGT1 1 0.01 0.28 0
92 INT307212 Ide Regulation of Lep 1 0.00 0.51 0
93 INT213584 Binding of AGTR2 and ACE 1 0.17 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hormone catabolic process. They are ordered first by their pain relevance and then by number of times they were reported in hormone catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
2 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46
3 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08
4 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19
5 INT56494 Localization of Ide 73 0.68 22.9 11.26
6 INT20664 Binding of ACE 60 0.48 35.27 9.16
7 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31
8 INT389 Gene_expression of Ace 21 0.67 10.31 8.1
9 INT25958 Regulation of Ace 26 0.59 11.88 7.87
10 INT1771 Positive_regulation of Ace 31 0.68 10.47 7.46
11 INT42038 Localization of ACE 26 0.80 8.88 7.06
12 INT56495 Positive_regulation of Localization of Ide 20 0.53 3.53 4.92
13 INT72703 Gene_expression of Ide 79 0.70 45.04 4.47
14 INT26477 Regulation of ACE 26 0.45 16.31 4.33
15 INT29327 Positive_regulation of Ace 13 0.67 8.79 4.33
16 INT387 Regulation of Ace 18 0.45 5.24 4.24
17 INT56493 Regulation of Localization of Ide 15 0.47 3.53 3.82
18 INT1722 Protein_catabolism of ACE 10 0.88 2.61 3.76
19 INT43085 Negative_regulation of Ide 28 0.39 19.96 3.45
20 INT8652 Protein_catabolism of Ace 10 0.94 4.7 2.74
21 INT191974 Regulation of Ide 16 0.38 9.54 2.52
22 INT74695 Gene_expression of Ace 41 0.73 53.33 2.33
23 INT388 Positive_regulation of Gene_expression of Ace 4 0.42 1.04 2.13
24 INT45646 Protein_catabolism of Ace 5 0.98 3.14 1.95
25 INT43084 Binding of Ace 10 0.46 4.7 1.93
26 INT33096 Negative_regulation of Gene_expression of ACE 9 0.43 2.84 1.93
27 INT55606 Binding of Ace 14 0.37 10.73 1.82
28 INT22335 Regulation of Negative_regulation of ACE 10 0.44 7.01 1.77
29 INT37294 Negative_regulation of Ece1 6 0.54 1.27 1.74
30 INT56497 Negative_regulation of Localization of Ide 12 0.44 5.34 1.42
31 INT191970 Positive_regulation of Ide 29 0.51 12.94 1.4
32 INT61223 Positive_regulation of Negative_regulation of ACE 6 0.49 5.92 1.37
33 INT92955 Gene_expression of Ece1 5 0.74 2.2 1.36
34 INT44145 Negative_regulation of Gene_expression of Ace 5 0.40 4.5 1.33
35 INT92954 Positive_regulation of Gene_expression of Ece1 2 0.48 2.16 1.32
36 INT95270 Regulation of Ece1 1 0.43 2.08 1.3
37 INT87233 Gene_expression of ECE1 12 0.65 3.54 1.12
38 INT88948 Localization of Ace 9 0.69 9.18 1.11
39 INT182516 Negative_regulation of Negative_regulation of ACE 9 0.42 6.84 0.99
40 INT297531 Negative_regulation of Ece1 5 0.32 5.49 0.87
41 INT83995 Positive_regulation of Gene_expression of ACE 8 0.68 8.09 0.82
42 INT230803 Regulation of Negative_regulation of Ace 2 0.39 1.89 0.81
43 INT286615 Phosphorylation of Ide 7 0.31 5.22 0.7
44 INT259902 Regulation of Gene_expression of ACE 3 0.45 1.87 0.7
45 INT268451 Positive_regulation of Gene_expression of ECE1 3 0.49 1.99 0.67
46 INT191978 Positive_regulation of Gene_expression of Ide 16 0.63 6.8 0.65
47 INT72446 Negative_regulation of Binding of ACE 4 0.42 2.48 0.62
48 INT56045 Positive_regulation of Localization of ACE 3 0.69 1.38 0.6
49 INT200636 Regulation of Gene_expression of Ace 1 0.26 1.64 0.6
50 INT210522 Protein_catabolism of Ide 16 0.79 7.73 0.55
51 INT88705 Localization of Ece1 2 0.22 2.07 0.55
52 INT87230 Localization of ECE1 5 0.80 1.51 0.53
53 INT210539 Binding of Ide 11 0.29 6.09 0.52
54 INT22333 Regulation of Negative_regulation of Ace 3 0.45 0.72 0.52
55 INT36764 Localization of Ace 7 0.80 1.53 0.51
56 INT43091 Positive_regulation of Negative_regulation of Ace 3 0.30 1.51 0.48
57 INT329319 Positive_regulation of Transcription of Ece1 1 0.08 2.64 0.48
58 INT191968 Negative_regulation of Gene_expression of Ide 9 0.39 7.14 0.47
59 INT171150 Negative_regulation of Binding of Ace 2 0.17 2.67 0.44
60 INT44032 Regulation of Positive_regulation of Ace 1 0.38 0.1 0.43
61 INT93926 Gene_expression of Ece1 3 0.27 2.31 0.42
62 INT324886 Transcription of Ece1 2 0.37 1.95 0.4
63 INT114063 Negative_regulation of Localization of Ace 1 0.29 0.31 0.39
64 INT60040 Negative_regulation of Negative_regulation of Ace 6 0.43 3.64 0.38
65 INT181635 Positive_regulation of Protein_catabolism of ACE 1 0.15 0.41 0.38
66 INT77686 Transcription of Ace 2 0.65 2.65 0.37
67 INT229626 Negative_regulation of Localization of ACE 3 0.41 2 0.36
68 INT267844 Positive_regulation of Gene_expression of Ace 10 0.57 15.35 0.35
69 INT61124 Localization of Ece1 1 0.58 0.08 0.32
70 INT96863 Transcription of ACE 3 0.69 0.38 0.29
71 INT230864 Regulation of Binding of ACE 1 0.22 0.79 0.29
72 INT288846 Negative_regulation of Transcription of ACE 1 0.43 0 0.29
73 INT191535 Protein_catabolism of ECE1 1 0.07 1.03 0.28
74 INT229358 Negative_regulation of Protein_catabolism of Ace 1 0.40 0.93 0.27
75 INT47070 Positive_regulation of Localization of Ace 2 0.32 0.55 0.26
76 INT229357 Regulation of Binding of Ace 1 0.43 0.86 0.26
77 INT329320 Positive_regulation of Gene_expression of Ece1 1 0.09 1.31 0.24
78 INT65003 Negative_regulation of Negative_regulation of Ace 5 0.37 3.45 0.23
79 INT324884 Positive_regulation of Ece1 2 0.37 0.86 0.22
80 INT210525 Transcription of Ide 3 0.40 1.93 0.21
81 INT307794 Negative_regulation of Gene_expression of Ace 7 0.48 5.95 0.2
82 INT191971 Regulation of Gene_expression of Ide 5 0.45 1.97 0.2
83 INT324882 Regulation of Transcription of Ece1 1 0.24 0.66 0.19
84 INT69192 Positive_regulation of Positive_regulation of Ace 1 0.02 0 0.19
85 INT108414 Negative_regulation of Regulation of ACE 1 0.43 0.67 0.17
86 INT87231 Binding of ECE1 4 0.37 0.47 0.16
87 INT210533 Negative_regulation of Binding of Ide 3 0.25 1.93 0.16
88 INT204171 Negative_regulation of Positive_regulation of Ide 2 0.06 1.73 0.16
89 INT44051 Positive_regulation of Protein_catabolism of Ace 1 0.41 0 0.16
90 INT242135 Regulation of Transcription of Ide 1 0.03 0.62 0.14
91 INT59791 Positive_regulation of Negative_regulation of Ace 3 0.49 0.57 0.13
92 INT242147 Positive_regulation of Transcription of Ide 1 0.03 0.63 0.13
93 INT242133 Negative_regulation of Transcription of Ide 1 0.03 0.62 0.13
94 INT161805 Positive_regulation of ECE1 1 0.12 0.61 0.13
95 INT249970 Transcription of Ace 3 0.36 1.87 0.12
96 INT331058 Regulation of Phosphorylation of Ide 1 0.03 0.36 0.12
97 INT43092 Negative_regulation of Binding of Ace 1 0.31 0 0.12
98 INT204168 Positive_regulation of Negative_regulation of Ide 2 0.29 1.34 0.1
99 INT79993 Positive_regulation of Positive_regulation of ACE 2 0.49 0.78 0.1
100 INT340501 Regulation of Transcription of Ace 1 0.10 0.84 0.1
101 INT87232 Regulation of ECE1 1 0.45 0.16 0.1
102 INT49260 Negative_regulation of ECE1 7 0.57 0.24 0.08
103 INT210532 Positive_regulation of Protein_catabolism of Ide 2 0.40 0.86 0.07
104 INT340500 Negative_regulation of Transcription of Ace 1 0.10 0.78 0.07
105 INT249971 Positive_regulation of Transcription of Ace 1 0.35 0.47 0.06
106 INT128209 Positive_regulation of Regulation of Ace 1 0.42 0.4 0.06
107 INT354322 Negative_regulation of Regulation of Ide 1 0.16 0.69 0.05
108 INT126436 Regulation of Gene_expression of Ece1 1 0.21 0.05 0.05
109 INT42326 Negative_regulation of Regulation of Ace 1 0.15 0 0.05
110 INT230809 Positive_regulation of Localization of Ace 1 0.44 0.38 0.05
111 INT102927 Negative_regulation of Localization of Ace 3 0.58 1 0.03
112 INT255789 Protein_catabolism of Ece1 2 0.35 1.06 0
113 INT270742 Negative_regulation of Phosphorylation of ACE 1 0.40 0.65 0
114 INT270740 Phosphorylation of ACE 1 0.76 0.65 0
115 INT316367 Negative_regulation of Transcription of Ace 1 0.40 0.22 0
116 INT210521 Positive_regulation of Binding of Ide 1 0.29 0.6 0
117 INT226248 Negative_regulation of Negative_regulation of ECE1 1 0.05 0 0
118 INT354324 Positive_regulation of Phosphorylation of Ide 1 0.19 0.77 0
119 INT307796 Positive_regulation of Positive_regulation of Ace 1 0.39 1.33 0
120 INT191967 Positive_regulation of Positive_regulation of Ide 1 0.37 0.08 0
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