GO:0042470

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Name melanosome
Categary Component
Go Slim No
Go Link GO:0042470
Unique Molecular Interactions 551
Total Molecular Interactions 766
Total Single Events 4877
Pain Genes Associated 76

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for melanosome. They are ordered first by their pain relevance and then by number of times they were reported for melanosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT269444 Binding of RAB5A and HHIP 1 0.04 0 5.79
2 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
3 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
4 INT103669 Hps4 Positive_regulation of Mors1 1 0.01 0 2.7
5 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
6 INT18197 Ghrh Positive_regulation of Localization of Ggh 4 0.46 0 2.23
7 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
8 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93
9 INT43447 Binding of H3 and Hps4 1 0.07 0 1.82
10 INT30134 Binding of TPP1 and S100A9 1 0.13 0.74 1.69
11 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66
12 INT187175 Binding of BSG and PPIA 1 0.14 2.23 1.64
13 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56
14 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
15 INT104972 MITF Regulation of Transcription of TYR 1 0.20 0.35 1.45
16 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
17 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
18 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
19 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
20 INT172757 Rnpep Positive_regulation of Hps4 1 0.00 0 1.08
21 INT187176 Binding of BSG and MMP1 1 0.09 1.18 1.08
22 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
23 INT69874 POMC Negative_regulation of TYRP1 1 0.13 0 1.07
24 INT69871 ASIP Negative_regulation of TYRP1 1 0.36 0 1.07
25 INT269443 Positive_regulation of Binding of RAB5A and HHIP 1 0.04 0 1.06
26 INT107566 Penk Regulation of Hps4 1 0.00 0.1 1.04
27 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
28 INT107565 Hps4 Regulation of Mtr 1 0.00 0.1 1.04
29 INT137103 Sec22b Regulation of Htr1a 1 0.09 0 1.02
30 INT38579 Binding of POMC and Hps4 1 0.00 0.32 0.99
31 INT25272 Binding of Ggh and Ghrh 1 0.22 0 0.97
32 INT163265 Sst Negative_regulation of Tyr 1 0.00 0.22 0.95
33 INT302309 Hps4 Positive_regulation of Cia1 1 0.01 1.34 0.95
34 INT216736 Binding of ADORA2B and ATP6V0A1 2 0.08 0.06 0.93
35 INT53152 Rac1 Regulation of Scg2 1 0.03 0 0.9
36 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
37 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
38 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
39 INT190168 BSG Regulation of CDCP1 1 0.00 1.18 0.84
40 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82
41 INT269455 Binding of RAB5A and GOPC 1 0.08 0 0.82
42 INT347391 Positive_regulation of RYBP Positive_regulation of Sdcbp 1 0.00 0.22 0.79
43 INT347398 RYBP Positive_regulation of Positive_regulation of Sdcbp 1 0.00 0.22 0.79
44 INT258798 Binding of NR3C1 and HSP90AA1 1 0.01 1.09 0.78
45 INT231031 Egf Positive_regulation of Sec22b 1 0.03 0.05 0.76
46 INT37439 Binding of Shbdp1 and Tyr 1 0.01 0 0.76
47 INT113472 TNF Positive_regulation of Localization of MMP14 1 0.47 0.45 0.75
48 INT129557 Binding of Trpv2 and Trpv1 1 0.41 0.18 0.74
49 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
50 INT148909 Binding of GNA13 and TP53INP2 1 0.06 0.31 0.73
51 INT46917 Binding of Tyr and Positive_regulation of Penk 1 0.02 0 0.73
52 INT46919 Binding of Tyr and Positive_regulation of Vom1r1 1 0.00 0 0.73
53 INT126598 Binding of BSG and OPRK1 1 0.01 0.05 0.72
54 INT101675 Bcl2l11 Regulation of Localization of Ggh 1 0.03 0 0.72
55 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
56 INT117535 SND1 Positive_regulation of Gene_expression of TNF 1 0.06 0.29 0.71
57 INT117534 TNF Positive_regulation of Positive_regulation of SND1 1 0.06 0.29 0.7
58 INT257302 Cnp Regulation of Protein_catabolism of Pde5a 1 0.05 0.49 0.7
59 INT144124 Binding of P2rx6 and Trpv2 1 0.09 0 0.7
60 INT99172 Pomc Positive_regulation of Tyr 1 0.35 0.17 0.69
61 INT102762 Binding of POMC and TYR 1 0.12 0.35 0.69
62 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
63 INT291552 Binding of Dlat and Sec22b 1 0.01 0.95 0.67
64 INT291548 Binding of Gper and Sec22b 1 0.02 0.94 0.67
65 INT137102 Fst Regulation of Sec22b 1 0.07 0 0.67
66 INT344387 Efnb2 Positive_regulation of Phosphorylation of Tyr 1 0.01 1.05 0.66
67 INT27526 Binding of Sdcbp and Eda 1 0.13 0 0.65
68 INT231028 Positive_regulation of Sec22b Positive_regulation of Gene_expression of Paqr8 1 0.02 0 0.64
69 INT137099 Dlst Regulation of Sec22b 1 0.05 0 0.64
70 INT113473 RETNLB Positive_regulation of MMP14 1 0.01 0.37 0.64
71 INT99170 Binding of Mc1r and Tyr 1 0.11 0.2 0.64
72 INT30130 Binding of TYRP1 and Gast 1 0.06 0.09 0.63
73 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
74 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
75 INT13618 Acyp2-ps1 Negative_regulation of Localization of Ggh 1 0.07 0 0.62
76 INT79210 Hps4 Negative_regulation of Mme 1 0.00 0 0.62
77 INT326471 Binding of ATP6V0A1 and IGKV2D-29 1 0.00 0.09 0.62
78 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
79 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
80 INT36320 PDYN Negative_regulation of Ctsb 1 0.00 0 0.61
81 INT165844 Binding of ATF4 and HSP90AB1 1 0.15 0.34 0.61
82 INT70811 Penk Negative_regulation of Binding of Tyr 1 0.01 0 0.6
83 INT250054 Positive_regulation of Binding of Gpr143 and Spdya 1 0.04 0.52 0.59
84 INT250053 Binding of Gpr143 and Spdya 1 0.03 0.51 0.59
85 INT144071 TRPV1 Positive_regulation of Gene_expression of MMP14 1 0.21 0.5 0.58
86 INT339532 FGF2 Positive_regulation of YWHAZ 1 0.00 1.26 0.54
87 INT69178 Binding of SLC3A2 and Adarb1 1 0.00 0.16 0.53
88 INT269449 Positive_regulation of Binding of RAB5A and GOPC 1 0.11 0 0.53
89 INT231034 Sec22b Positive_regulation of Gene_expression of Pgr 1 0.04 0.09 0.53
90 INT160829 Tyr Regulation of RYBP 1 0.04 0.75 0.53
91 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52
92 INT1006 Sst Negative_regulation of Ggh 1 0.24 0 0.52
93 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52
94 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
95 INT23091 Tnf Positive_regulation of Localization of Ggh 1 0.05 0.15 0.5
96 INT23089 Tnf Positive_regulation of Ggh 1 0.04 0.15 0.5
97 INT47226 Asap1 Regulation of Hps4 1 0.10 0.18 0.49
98 INT31531 Mif-ps1 Regulation of TYR 1 0.11 0 0.49
99 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
100 INT345306 Binding of MMP14 and TIMP2 1 0.04 0.21 0.48
101 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 1 0.42 0.21 0.48
102 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 1 0.38 0.21 0.48
103 INT145954 Binding of BSG and MME 1 0.00 0.81 0.47
104 INT101003 GHRH Regulation of Localization of GGH 1 0.29 0 0.47
105 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
106 INT168699 Binding of Nedd4 and Tyr 1 0.02 0.45 0.46
107 INT65909 LAMB1 Positive_regulation of GANAB 1 0.00 0 0.45
108 INT335594 Myo5a Regulation of Hmmr 1 0.00 0.39 0.45
109 INT345305 MMP14 Positive_regulation of MMP13 1 0.00 0.33 0.45
110 INT345304 MMP14 Positive_regulation of MMP2 1 0.08 0.2 0.45
111 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
112 INT353698 NA Positive_regulation of Atp6v0a1 1 0.00 0.67 0.44
113 INT321046 Anpep Regulation of Negative_regulation of Hps4 1 0.02 0.25 0.43
114 INT113471 RETNLB Regulation of Localization of MMP14 1 0.01 0.24 0.43
115 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
116 INT269448 HHIP Positive_regulation of Binding of RAB5A 1 0.04 0 0.42
117 INT131505 Rac1 Regulation of Gene_expression of Trpv1 1 0.55 0.39 0.42
118 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
119 INT13620 Acyp2-ps1 Regulation of Localization of Ggh 1 0.07 0 0.41
120 INT335643 CTSB Positive_regulation of PAR4 1 0.01 1.3 0.41
121 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
122 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
123 INT10825 Binding of PDYN and Tyr 1 0.01 0 0.39
124 INT269456 RAB5A Regulation of Binding of HHIP 1 0.04 0 0.38
125 INT216738 Binding of ATP6V0A1 and TCFL5 1 0.01 0.06 0.38
126 INT342622 Binding of MMP14 and Mmp2 1 0.39 1.15 0.37
127 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37
128 INT35685 TYR Regulation of Oxt 1 0.14 0.32 0.36
129 INT93694 Binding of Hspa8 and Ptgs1 1 0.30 0.79 0.36
130 INT227943 Binding of Vip and Mlph 1 0.01 0.33 0.36
131 INT13616 Acyp2-ps1 Regulation of Ggh 1 0.07 0 0.36
132 INT99171 Negative_regulation of Pomc Positive_regulation of Tyr 1 0.22 0.08 0.35
133 INT190173 BSG Regulation of MMRN1 1 0.00 0.29 0.35
134 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
135 INT193784 ITIH4 Positive_regulation of YWHAZ 1 0.04 1.21 0.34
136 INT113476 IL1A Positive_regulation of Localization of MMP14 1 0.10 0.22 0.34
137 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
138 INT227496 PTPN4 Regulation of PMEL 1 0.00 0.45 0.33
139 INT188521 Binding of Hsp90aa1 and Ptges3 1 0.02 0.61 0.33
140 INT40855 GGH Regulation of PRL 1 0.10 0 0.32
141 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
142 INT295722 PTGER2 Positive_regulation of RAC1 1 0.02 2.14 0.32
143 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
144 INT113475 RETNLB Positive_regulation of Localization of MMP14 1 0.01 0.18 0.32
145 INT318323 Binding of GRB2 and HSPA5 1 0.34 0.28 0.31
146 INT169612 OGFR Regulation of RAN 1 0.23 0.14 0.3
147 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
148 INT50107 Ei24 Positive_regulation of Localization of CTSB 3 0.00 0.6 0.29
149 INT104048 Binding of SLC3A2 and Pomc 1 0.05 0 0.28
150 INT258858 CTSB Positive_regulation of Gene_expression of IL8 1 0.00 0.64 0.28
151 INT172465 Binding of Rab27a and Rab27b 2 0.41 1.71 0.27
152 INT149898 Ihh Regulation of Localization of Mmp14 1 0.03 1.29 0.27
153 INT293900 TYRP1 Regulation of IGKC 1 0.01 0.11 0.27
154 INT71640 Binding of HLA-A and TYR 1 0.16 0.36 0.27
155 INT229785 Binding of RAB7A and SPTLC1 1 0.40 1.5 0.27
156 INT71642 Binding of HLA-A and PMEL 2 0.20 1.05 0.26
157 INT118848 GNA14 Positive_regulation of RAC1 1 0.01 0.14 0.26
158 INT71643 Binding of HLA-A and TYRP1 1 0.24 0.36 0.26
159 INT307009 MT1JP Positive_regulation of Gene_expression of LAMP1 1 0.03 0.58 0.26
160 INT71641 Binding of MLANA and HLA-A 1 0.28 0.36 0.26
161 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26
162 INT71639 Binding of MLANA and PMEL 1 0.27 0.36 0.26
163 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26
164 INT244687 Mmp14 Positive_regulation of Mmp2 1 0.23 0.48 0.25
165 INT111909 Binding of HSPD1 and CCT4 1 0.29 0.48 0.25
166 INT126227 Hsp90aa1 Positive_regulation of Nos1 1 0.03 0.73 0.25
167 INT86634 POMC Positive_regulation of TYR 2 0.42 0 0.24
168 INT333927 GLUL Positive_regulation of HSPA5 1 0.17 0.78 0.24
169 INT292561 MAP3K5 Positive_regulation of Positive_regulation of RAC1 1 0.03 0 0.23
170 INT169611 Binding of RAN and OGFR 1 0.24 0.19 0.23
171 INT298876 RAB7A Positive_regulation of Protein_catabolism of NTRK1 1 0.14 0.44 0.22
172 INT231036 Negative_regulation of Prkaca Negative_regulation of Positive_regulation of Sec22b 1 0.01 0 0.22
173 INT60909 TPP1 Positive_regulation of Gh1 1 0.00 0 0.22
174 INT149900 Gli1 Regulation of Localization of Mmp14 1 0.02 1.17 0.22
175 INT10363 Binding of Tmem33 and RT1-Db1 1 0.00 0.92 0.21
176 INT64382 Positive_regulation of Binding of YY1 and Tyr 1 0.11 0 0.21
177 INT146720 Cck Regulation of Cnp 1 0.12 0.43 0.21
178 INT322011 BSG Regulation of P2RX7 1 0.00 0.48 0.21
179 INT64383 Binding of YY1 and Tyr 1 0.09 0 0.21
180 INT323346 Positive_regulation of Tyrp1 Positive_regulation of Positive_regulation of Gpr35 1 0.11 0.76 0.21
181 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
182 INT151424 Tfrc Negative_regulation of Positive_regulation of Tnni3 1 0.21 0.98 0.2
183 INT143973 Rac1 Positive_regulation of Vti1b 1 0.00 0.16 0.2
184 INT224086 Binding of Agtr1a and Hspa8 1 0.00 0.1 0.19
185 INT13020 Binding of SCN4A and GANAB 1 0.15 0.95 0.19
186 INT148835 asa Negative_regulation of Tyr 1 0.33 0.58 0.18
187 INT308518 HSP90B1 Positive_regulation of Positive_regulation of SOAT1 1 0.00 0.65 0.18
188 INT313799 Binding of HLA-B and TYRP1 1 0.01 0.54 0.18
189 INT245183 Binding of CTSB and TCF7L2 1 0.39 6.39 0.18
190 INT231029 Ppidl1 Positive_regulation of Sec22b 1 0.00 0 0.18
191 INT216842 ATP6V0A1 Negative_regulation of ADCY1 1 0.01 0.35 0.18
192 INT12525 Binding of POMC and GANAB 1 0.04 1.9 0.17
193 INT231033 Igf1 Positive_regulation of Sec22b 1 0.06 0 0.17
194 INT275318 Binding of Gpr143 and Adamts4 1 0.00 0.6 0.17
195 INT93693 Positive_regulation of Binding of Hspa8 and Ptgs1 1 0.31 0.38 0.17
196 INT130690 Gene_expression of HSPA5 Negative_regulation of Positive_regulation of DDIT3 1 0.21 0.58 0.17
197 INT275319 Tg(Ngf)47Kma Positive_regulation of Gpr143 1 0.00 0.59 0.17
198 INT162273 KITLG Negative_regulation of Gene_expression of Tyr 1 0.13 0.3 0.17
199 INT275317 Binding of Gpr143 and Adamts5 1 0.01 0.61 0.17
200 INT168700 Positive_regulation of Binding of Nedd4 and Tyr 1 0.03 0.19 0.17

Single Events

The table below shows the top 100 pain related interactions that have been reported for melanosome. They are ordered first by their pain relevance and then by number of times they were reported in melanosome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT81251 Gene_expression of Trpv2 78 0.78 28.27 41.76
2 INT16290 Gene_expression of BSG 60 0.68 38.73 32.86
3 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
4 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
5 INT35711 Positive_regulation of Sdcbp 110 0.60 50.45 22.11
6 INT32648 Gene_expression of Tyrp1 80 0.66 17.9 16.59
7 INT1000 Localization of Ggh 31 0.75 2.74 16.41
8 INT30440 Gene_expression of Hps4 15 0.29 2.39 15.31
9 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
10 INT18430 Positive_regulation of Hps4 14 0.24 0.81 14.82
11 INT35120 Gene_expression of Sdcbp 68 0.67 21.33 13.96
12 INT27627 Binding of Rac1 41 0.41 22.88 13.68
13 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52
14 INT81249 Positive_regulation of Trpv2 21 0.70 8.13 12.36
15 INT222660 Phosphorylation of Tyr 2 0.06 5.31 12.33
16 INT96406 Regulation of Trpv2 14 0.62 7.45 12.04
17 INT30236 Negative_regulation of Hps4 8 0.15 1.03 11.4
18 INT2260 Gene_expression of Tyr 30 0.49 7.05 11.31
19 INT85631 Positive_regulation of Tyrp1 40 0.64 18.73 10.84
20 INT244490 Gene_expression of HSP90B1 4 0.33 41.16 10.37
21 INT18429 Localization of Hps4 8 0.31 1.23 9.01
22 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
23 INT43811 Positive_regulation of Tyr 14 0.45 2.52 8.86
24 INT13010 Gene_expression of TYR 38 0.65 14.81 8.84
25 INT3622 Regulation of CTSB 34 0.58 16.08 8.76
26 INT15805 Gene_expression of TFRC 35 0.75 17.44 8.52
27 INT18185 Gene_expression of Tyr 32 0.76 12.52 8.17
28 INT5481 Binding of TYR 26 0.47 1.3 7.95
29 INT7168 Positive_regulation of Ctsb 9 0.70 0.3 7.58
30 INT43441 Binding of Hps4 7 0.24 0.46 7.43
31 INT31911 Regulation of Hps4 5 0.19 2.16 6.83
32 INT35712 Regulation of Sdcbp 19 0.23 5.3 6.58
33 INT250050 Gene_expression of Gpr143 1 0.48 5.76 6.53
34 INT234813 Gene_expression of RAB5A 58 0.66 3.67 6.48
35 INT250048 Positive_regulation of Gpr143 12 0.43 5.85 6.1
36 INT49027 Gene_expression of TYRP1 35 0.75 9.81 6.06
37 INT117621 Positive_regulation of HSPA5 17 0.59 13.26 6.06
38 INT37745 Positive_regulation of Gene_expression of Sdcbp 22 0.60 5.15 6.02
39 INT135106 Positive_regulation of Sec22b 15 0.27 1.89 5.99
40 INT1002 Regulation of Localization of Ggh 10 0.58 0.63 5.98
41 INT103918 Phosphorylation of Tyr 12 0.47 10.12 5.96
42 INT8157 Binding of Tyr 14 0.09 0.64 5.89
43 INT49025 Positive_regulation of TYR 14 0.69 7.15 5.84
44 INT93165 Gene_expression of TRPV2 32 0.78 12.49 5.62
45 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54
46 INT114993 Binding of Myo5a 15 0.30 11.46 5.48
47 INT50105 Localization of CTSB 29 0.78 10.98 5.21
48 INT114627 Positive_regulation of Gene_expression of Trpv2 9 0.70 6.41 5.18
49 INT68591 Regulation of TYRP1 14 0.44 3.93 5.05
50 INT7479 Positive_regulation of Ggh 13 0.62 5.71 5.02
51 INT187189 Positive_regulation of Gene_expression of BSG 1 0.61 6.21 5.02
52 INT216754 Binding of ATP6V0A1 5 0.11 0.71 4.98
53 INT255981 Localization of RAB5A 3 0.68 0.88 4.76
54 INT7170 Positive_regulation of Positive_regulation of Ctsb 1 0.40 0 4.76
55 INT269476 Binding of RAB5A 1 0.41 0 4.76
56 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
57 INT124136 Positive_regulation of YWHAZ 7 0.67 1.85 4.51
58 INT107605 Gene_expression of MMP14 26 0.64 25.88 4.49
59 INT35122 Negative_regulation of Sdcbp 43 0.51 22.01 4.34
60 INT32569 Localization of GGH 18 0.80 2.46 4.3
61 INT81250 Transcription of Trpv2 7 0.64 1.54 4.27
62 INT32446 Localization of Tyr 11 0.68 1.31 4.25
63 INT113485 Localization of MMP14 11 0.77 3.44 4.19
64 INT44789 Binding of Sdcbp 10 0.36 1.65 4.01
65 INT4530 Regulation of Ggh 9 0.54 2.5 3.96
66 INT124028 Localization of Trpv2 6 0.80 2.04 3.96
67 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75
68 INT142501 Transcription of Tyrp1 4 0.18 2.09 3.71
69 INT31528 Regulation of TYR 6 0.44 0.83 3.63
70 INT20265 Gene_expression of Ctsb 3 0.47 1.01 3.52
71 INT121967 Regulation of RAC1 9 0.45 6.14 3.41
72 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
73 INT18073 Positive_regulation of TYRP1 11 0.67 1.98 3.36
74 INT59447 Negative_regulation of Tyr 12 0.56 4.57 3.32
75 INT151421 Negative_regulation of Positive_regulation of Sdcbp 11 0.30 6.61 3.32
76 INT15801 Positive_regulation of TFRC 11 0.33 6.35 3.3
77 INT192450 Gene_expression of CLTC 26 0.55 18.82 3.26
78 INT7773 Localization of SERPINF1 18 0.55 8.54 3.25
79 INT58475 Localization of Rac1 12 0.75 5.94 3.2
80 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16
81 INT244512 Positive_regulation of Gene_expression of HSP90B1 2 0.30 12.08 3.12
82 INT76403 Gene_expression of Cnp 16 0.70 8.36 3.07
83 INT37435 Negative_regulation of Tyr 6 0.14 0.96 2.94
84 INT52878 Positive_regulation of ATP6V0A1 9 0.54 1.35 2.92
85 INT130700 Gene_expression of HSPA5 16 0.75 11.55 2.81
86 INT187187 Regulation of Gene_expression of BSG 3 0.40 3.84 2.8
87 INT32787 Positive_regulation of Gene_expression of Tyr 5 0.38 0.37 2.77
88 INT72812 Positive_regulation of BSG 2 0.49 2.2 2.76
89 INT30437 Negative_regulation of Gene_expression of Hps4 1 0.03 0 2.74
90 INT234825 Positive_regulation of Gene_expression of RAB5A 16 0.59 1.15 2.71
91 INT110980 Gene_expression of CTSB 17 0.45 8.02 2.69
92 INT49020 Negative_regulation of TYR 11 0.58 1.97 2.68
93 INT130702 Positive_regulation of Gene_expression of HSPA5 7 0.59 7.53 2.68
94 INT5789 Gene_expression of PMEL 23 0.75 13.18 2.67
95 INT83073 Negative_regulation of Tyrp1 10 0.23 4.4 2.65
96 INT29879 Positive_regulation of GGH 9 0.70 3.13 2.62
97 INT51753 Negative_regulation of Tfrc 7 0.41 3.47 2.62
98 INT30040 Negative_regulation of TYRP1 11 0.51 2.72 2.54
99 INT73028 Positive_regulation of Transcription of Ctsb 1 0.55 1.53 2.54
100 INT59135 Positive_regulation of CTSB 15 0.67 7.53 2.53
101 INT123016 Gene_expression of Sec22b 11 0.41 5.1 2.5
102 INT13608 Negative_regulation of Localization of Ggh 5 0.45 1.97 2.43
103 INT37341 Regulation of Tyrp1 4 0.29 4.53 2.42
104 INT61441 Negative_regulation of Gene_expression of Tyr 3 0.10 0.69 2.4
105 INT21726 Gene_expression of Tfrc 10 0.74 7.38 2.36
106 INT11353 Gene_expression of SLC3A2 13 0.58 7.31 2.33
107 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
108 INT37427 Positive_regulation of Gene_expression of Ctsb 2 0.37 1.02 2.33
109 INT85630 Positive_regulation of Tyr 11 0.56 3.07 2.31
110 INT7173 Regulation of Positive_regulation of Ctsb 1 0.49 0 2.29
111 INT99865 Binding of Trpv2 4 0.48 1.13 2.25
112 INT124138 Gene_expression of YWHAZ 9 0.62 4.04 2.21
113 INT30137 Negative_regulation of TPP1 5 0.37 0.96 2.2
114 INT6635 Negative_regulation of Cnp 9 0.57 5.85 2.15
115 INT92542 Negative_regulation of Trpv2 8 0.59 1.54 2.15
116 INT70987 Binding of RAC1 14 0.37 12.14 2.13
117 INT14010 Gene_expression of SLC2A1 19 0.78 15.22 2.12
118 INT999 Positive_regulation of Localization of Ggh 4 0.65 0 2.12
119 INT11388 Positive_regulation of PMEL 11 0.67 5.9 2.09
120 INT128210 Positive_regulation of Positive_regulation of Sdcbp 6 0.08 3.88 2.08
121 INT14850 Binding of Slc3a2 4 0.15 1.5 2.07
122 INT40647 Gene_expression of Ggh 5 0.59 0.24 2.03
123 INT82543 Negative_regulation of Gene_expression of TFRC 4 0.57 1.27 2.03
124 INT83332 Regulation of Gene_expression of TFRC 5 0.22 3.03 1.99
125 INT6218 Gene_expression of Slc3a2 6 0.48 0.51 1.97
126 INT12849 Negative_regulation of Atp6v0a1 5 0.51 0.64 1.89
127 INT20094 Binding of Pdia3 3 0.31 1.26 1.87
128 INT107607 Negative_regulation of MMP14 10 0.37 6.05 1.83
129 INT35121 Negative_regulation of Gene_expression of Sdcbp 6 0.43 2.4 1.83
130 INT71644 Gene_expression of MLANA 16 0.75 11.55 1.82
131 INT77656 Gene_expression of Hsp90aa1 12 0.78 24.27 1.81
132 INT96746 Gene_expression of Lamp1 2 0.03 1.82 1.81
133 INT57018 Gene_expression of GANAB 9 0.08 3.76 1.79
134 INT231050 Positive_regulation of Positive_regulation of Sec22b 1 0.09 0 1.78
135 INT32568 Positive_regulation of Localization of GGH 4 0.65 0.42 1.72
136 INT43542 Regulation of Localization of GGH 3 0.62 0.17 1.71
137 INT113479 Transcription of MMP14 3 0.51 1.81 1.7
138 INT124137 Positive_regulation of Positive_regulation of YWHAZ 1 0.67 0 1.7
139 INT50106 Positive_regulation of Localization of CTSB 9 0.33 3.15 1.69
140 INT234827 Positive_regulation of RAB5A 3 0.59 0.54 1.69
141 INT30138 Binding of TPP1 1 0.16 0.74 1.69
142 INT73027 Transcription of Ctsb 1 0.56 1.01 1.68
143 INT125245 Positive_regulation of Mmp14 4 0.44 4.38 1.67
144 INT300417 Localization of Tyr 5 0.11 0.26 1.65
145 INT115309 Gene_expression of Slc2a1 6 0.75 2.85 1.64
146 INT71780 Phosphorylation of TYR 12 0.34 17.21 1.62
147 INT30037 Binding of TYRP1 9 0.36 0.45 1.6
148 INT6438 Positive_regulation of RAN 6 0.42 2.09 1.59
149 INT17885 Negative_regulation of YWHAZ 6 0.56 2.74 1.58
150 INT202935 Gene_expression of SERPINF1 12 0.50 7.53 1.54
151 INT99357 Positive_regulation of Localization of PMEL 1 0.67 0.51 1.52
152 INT37104 Binding of GANAB 2 0.27 1.76 1.51
153 INT172752 Protein_catabolism of Hps4 2 0.16 0.22 1.51
154 INT159091 Positive_regulation of Regulation of Sdcbp 1 0.40 0.16 1.5
155 INT205190 Localization of Sec22b 8 0.09 2.36 1.48
156 INT59795 Regulation of Tfrc 5 0.43 4.43 1.48
157 INT125800 Gene_expression of P4HB 5 0.47 5.4 1.47
158 INT30439 Positive_regulation of Gene_expression of Hps4 1 0.02 0 1.47
159 INT197889 Binding of Sec22b 7 0.04 4.38 1.46
160 INT145177 Positive_regulation of Gene_expression of Tyrp1 5 0.30 3.31 1.46
161 INT308527 Regulation of Gene_expression of HSP90B1 2 0.26 5.31 1.46
162 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
163 INT125320 Negative_regulation of HSP90AA1 20 0.45 23.93 1.42
164 INT15798 Positive_regulation of Gene_expression of TFRC 9 0.46 4.99 1.42
165 INT62425 Regulation of Gene_expression of Tyrp1 7 0.29 1.44 1.41
166 INT58930 Negative_regulation of RAC1 14 0.55 7.55 1.4
167 INT323338 Positive_regulation of Positive_regulation of Tyrp1 2 0.13 1.53 1.4
168 INT151095 Gene_expression of ATP6V0A1 13 0.48 4.4 1.37
169 INT42335 Binding of CTSB 11 0.34 5.98 1.37
170 INT311241 Transcription of Myo5a 1 0.50 1.61 1.37
171 INT45233 Positive_regulation of Binding of Sdcbp 1 0.07 0 1.36
172 INT162196 Binding of Tyrp1 2 0.31 0.69 1.35
173 INT154026 Negative_regulation of Regulation of Sdcbp 1 0.37 0 1.35
174 INT88855 Negative_regulation of Hsp90aa1 4 0.54 2.16 1.34
175 INT229794 Positive_regulation of RAB7A 2 0.65 11.68 1.31
176 INT250046 Regulation of Gene_expression of Gpr143 1 0.28 0.87 1.23
177 INT98062 Regulation of Gene_expression of Rac1 4 0.39 1.41 1.21
178 INT229791 Gene_expression of RAB7A 2 0.73 6.48 1.21
179 INT6996 Positive_regulation of Tfrc 6 0.70 2.22 1.2
180 INT229792 Negative_regulation of Positive_regulation of RAB7A 1 0.40 1.49 1.17
181 INT93506 Negative_regulation of Gene_expression of Tyr 2 0.57 1.61 1.15
182 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13
183 INT353696 Regulation of Gene_expression of Cnp 1 0.22 1.49 1.13
184 INT133898 Binding of HSP90AA1 17 0.30 8.83 1.12
185 INT20317 Localization of Ctsb 3 0.81 0.68 1.12
186 INT103919 Negative_regulation of Phosphorylation of Tyr 2 0.32 2.01 1.12
187 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12
188 INT168675 Binding of P4HB 3 0.20 1.98 1.11
189 INT59136 Negative_regulation of Positive_regulation of CTSB 3 0.41 2.02 1.11
190 INT29883 Regulation of GGH 4 0.27 0 1.1
191 INT154437 Positive_regulation of Slc2a1 4 0.26 2.67 1.08
192 INT293195 Positive_regulation of Phosphorylation of Tyr 1 0.01 0.76 1.08
193 INT278100 Regulation of ATP6V0A1 5 0.19 1.5 1.07
194 INT82540 Negative_regulation of TFRC 3 0.41 0.77 1.07
195 INT125248 Negative_regulation of Mmp14 1 0.06 3.06 1.07
196 INT247970 Regulation of CLTC 8 0.28 5.37 1.06
197 INT2293 Localization of TYR 3 0.61 0.16 1.06
198 INT69309 Positive_regulation of Gene_expression of PMEL 3 0.49 0.9 1.05
199 INT124135 Positive_regulation of Gene_expression of YWHAZ 2 0.45 0.21 1.05
200 INT90898 Negative_regulation of Rab27a 5 0.43 1.99 1.04
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