GO:0042474

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Name middle ear morphogenesis
Categary Process
Go Slim No
Go Link GO:0042474
Unique Molecular Interactions 304
Total Molecular Interactions 407
Total Single Events 2967
Pain Genes Associated 21

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for middle ear morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for middle ear morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
2 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
3 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
4 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
5 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
6 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
7 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
8 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
9 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
10 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
11 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
12 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
13 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
14 INT116269 Binding of Myc and Mycbp2 1 0.19 0.5 0.87
15 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
16 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82
17 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
18 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
19 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
20 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
21 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
22 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
23 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
24 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
25 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
26 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
27 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
28 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
29 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
30 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
31 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
32 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
33 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
34 INT131642 Edn1 Positive_regulation of Positive_regulation of Insrr 1 0.01 0.44 0.6
35 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
36 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
37 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
38 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
39 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
40 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
41 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
42 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
43 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
44 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
45 INT50497 Edn1 Positive_regulation of Pla2g1b 1 0.01 0.23 0.45
46 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
47 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
48 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
49 INT153766 Edn1 Positive_regulation of Gtf3a 1 0.04 1.25 0.41
50 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
51 INT99399 Penk Positive_regulation of Edn1 1 0.00 0 0.38
52 INT99400 Gast Positive_regulation of Edn1 1 0.00 0 0.38
53 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37
54 INT313701 Calca Negative_regulation of Binding of Edn1 1 0.30 0.14 0.37
55 INT152314 Il18 Regulation of Edn1 1 0.02 0.22 0.36
56 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
57 INT152316 Ifng Regulation of Edn1 1 0.01 0.22 0.35
58 INT168202 Msx1 Negative_regulation of Gene_expression of Mc1r 1 0.21 0.49 0.35
59 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
60 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
61 INT207576 RETN Positive_regulation of Gene_expression of EDN1 1 0.05 0.78 0.33
62 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
63 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32
64 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
65 INT182262 EDN1 Positive_regulation of Gene_expression of NOS2 1 0.28 0.79 0.31
66 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31
67 INT75056 Binding of MC1R and Msx1 1 0.00 0.17 0.29
68 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
69 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26
70 INT327300 Binding of Hnrnpd and Myc 1 0.12 1.02 0.25
71 INT168203 Binding of Mc1r and Msx1 1 0.19 0.64 0.25
72 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
73 INT178095 EDN1 Positive_regulation of MMP3 1 0.04 0.88 0.24
74 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24
75 INT178085 EDN1 Positive_regulation of MMP7 1 0.06 0.89 0.24
76 INT178141 EDN1 Positive_regulation of Timp1 1 0.30 0.89 0.24
77 INT178075 EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
78 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 0.05 0.83 0.24
79 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
80 INT178142 EDN1 Positive_regulation of Localization of Timp1 1 0.28 0.89 0.24
81 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24
82 INT182272 EDN1 Regulation of Gene_expression of MMP13 1 0.26 0.87 0.22
83 INT9717 Binding of Egf and Fgfr1 1 0.15 0 0.22
84 INT91686 Mb Positive_regulation of Edn1 1 0.03 0.29 0.22
85 INT182265 EDN1 Positive_regulation of NOS2 1 0.24 0.56 0.22
86 INT115148 PPARG Negative_regulation of Gene_expression of INSIG2 1 0.01 0.34 0.21
87 INT182263 EDN1 Positive_regulation of MMP1 1 0.15 0.43 0.21
88 INT75057 Binding of POMC and Msx1 2 0.39 0.6 0.2
89 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2
90 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
91 INT182258 EDN1 Positive_regulation of Positive_regulation of MMP1 1 0.15 0.47 0.19
92 INT182271 EDN1 Positive_regulation of Localization of MMP13 1 0.27 0.47 0.19
93 INT219915 Edn1 Regulation of Positive_regulation of Trpv1 1 0.33 0 0.18
94 INT140096 Gtf3a Positive_regulation of Gene_expression of Edn1 1 0.02 0.44 0.18
95 INT171386 Edn1 Positive_regulation of Mapk1 1 0.05 0.13 0.18
96 INT60778 Edn1 Positive_regulation of EDNRA 1 0.00 0 0.18
97 INT284450 Edn1 Positive_regulation of Gene_expression of MMP9 1 0.01 0.3 0.18
98 INT140094 Ifng Regulation of Gene_expression of Edn1 1 0.18 0.44 0.18
99 INT306425 Positive_regulation of Binding of TBX1 and VCF 1 0.02 1.15 0.18
100 INT306426 Binding of TBX1 and VCF 1 0.01 1.09 0.17
101 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
102 INT203759 Binding of EDN1 and TNF 1 0.16 0.71 0.16
103 INT324899 Edn1 Positive_regulation of Positive_regulation of Mmp9 1 0.10 0.66 0.16
104 INT94022 Positive_regulation of Binding of EDN1 and INSRR 1 0.06 0 0.16
105 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.91 0.16
106 INT94021 Binding of EDN1 and EDN2 1 0.26 0 0.16
107 INT94014 Positive_regulation of Binding of EDN1 and EDN3 1 0.36 0 0.16
108 INT116268 Binding of Myc and Acsl1 1 0.08 0.19 0.16
109 INT324894 Edn1 Positive_regulation of Gene_expression of Mmp3 1 0.07 0.66 0.16
110 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15
111 INT21509 Agt Regulation of Edn1 1 0.53 0 0.15
112 INT182261 EDN1 Regulation of Gene_expression of MMP1 1 0.17 0.7 0.15
113 INT97547 KITLG Negative_regulation of Msx1 1 0.00 0.08 0.15
114 INT97542 Pomc Negative_regulation of Msx1 1 0.13 0.07 0.15
115 INT97545 Gtf3a Negative_regulation of Msx1 1 0.02 0.08 0.15
116 INT50500 Edn1 Positive_regulation of PTGS1 1 0.00 0.07 0.14
117 INT324898 Ece1 Regulation of Gene_expression of Edn1 1 0.17 0.8 0.14
118 INT161799 Positive_regulation of Binding of ECE1 and EDN1 1 0.07 0.68 0.14
119 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14
120 INT184704 Binding of Prrx2 and Sr1 1 0.21 1.65 0.13
121 INT201722 Myc Regulation of Gene_expression of Ccnd1 1 0.03 0.79 0.13
122 INT320261 Binding of Myc and Ntrk2 1 0.01 0.36 0.13
123 INT323430 Binding of Vhl and Osr1 1 0.02 0.78 0.13
124 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
125 INT161798 Positive_regulation of Binding of EDN1 and ING1 1 0.06 0.66 0.13
126 INT161800 Binding of EDN1 and ING1 1 0.05 0.65 0.13
127 INT178083 EDN1 Positive_regulation of Gene_expression of VEGFA 1 0.09 1.8 0.13
128 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13
129 INT323435 Binding of Osr1 and Gtf3a 1 0.00 0.78 0.13
130 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13
131 INT262197 Nr1i2 Positive_regulation of Insig1 2 0.23 0 0.12
132 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12
133 INT173200 PPA1 Positive_regulation of Myc 1 0.08 0.5 0.12
134 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
135 INT77863 EDN1 Positive_regulation of POMC 1 0.50 0.34 0.12
136 INT261690 Binding of GSC and TCF23 1 0.10 0 0.12
137 INT214150 Binding of Mc3r and Msx1 1 0.03 0.5 0.12
138 INT182273 EDN1 Regulation of Gene_expression of BAD 1 0.11 0.73 0.12
139 INT281192 Casr Positive_regulation of Insig1 1 0.23 0 0.12
140 INT180445 Edn1 Positive_regulation of Rhoa 1 0.08 0.57 0.11
141 INT214152 Binding of Mc4r and Msx1 1 0.03 0.24 0.11
142 INT182270 EDN1 Positive_regulation of Gene_expression of MMP1 1 0.18 0.55 0.1
143 INT181569 Binding of Edn1 and Mapk8 1 0.09 2.7 0.1
144 INT181570 Binding of Edn1 and Mapk1 1 0.13 2.72 0.1
145 INT6674 Edn1 Positive_regulation of Gene_expression of FOS 1 0.08 0.19 0.1
146 INT139476 Edn1 Positive_regulation of Ednra 1 0.00 1.07 0.1
147 INT10904 Edn1 Regulation of Localization of Nppb 1 0.22 0.54 0.1
148 INT92956 Edn1 Regulation of Positive_regulation of Nos2 1 0.18 0.17 0.09
149 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 0.10 0.57 0.09
150 INT230750 Crp Positive_regulation of Edn1 1 0.10 0.27 0.09
151 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09
152 INT214168 Msx1 Positive_regulation of Gene_expression of DST 1 0.00 0.13 0.09
153 INT188964 Binding of AMBP and NAGLU 1 0.01 1.27 0.09
154 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09
155 INT92957 Edn1 Regulation of Gene_expression of Nos2 1 0.18 0.17 0.09
156 INT221653 Binding of Myc and Gopc 2 0.12 0.51 0.08
157 INT242257 Binding of EDN1 and ELF3 1 0.17 0.21 0.08
158 INT181584 Binding of EDNRB and Edn1 1 0.46 0.85 0.08
159 INT288374 Binding of MLANA and Msx1 1 0.09 0 0.08
160 INT181583 Binding of Edn1 and Positive_regulation of NOS1 1 0.02 0.86 0.08
161 INT178100 Gene_expression of EDNRB Positive_regulation of EDN1 1 0.17 1.11 0.08
162 INT113369 Edn1 Regulation of Adarb1 1 0.02 0.14 0.08
163 INT178081 Negative_regulation of EDN1 Positive_regulation of HIF1A 1 0.04 1.18 0.08
164 INT178080 EDN1 Positive_regulation of HIF1A 1 0.05 1.05 0.08
165 INT228501 Binding of AAVS1 and Fgfr1 1 0.01 0.57 0.07
166 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07
167 INT182269 EDN1 Positive_regulation of Localization of MMP1 1 0.17 0.31 0.07
168 INT192908 Edn1 Positive_regulation of Ednra 1 0.21 0.35 0.07
169 INT242258 ELF3 Negative_regulation of EDN1 1 0.15 0.09 0.07
170 INT309941 Edn1 Positive_regulation of Tlr2 1 0.02 1.31 0.07
171 INT172382 AGT Positive_regulation of Localization of EDN1 1 0.03 0.34 0.07
172 INT182268 Negative_regulation of MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
173 INT192907 Edn1 Positive_regulation of Ednrb 1 0.10 0.35 0.07
174 INT182274 MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
175 INT191219 Edn1 Positive_regulation of Amigo2 1 0.06 1.26 0.07
176 INT324896 Ece1 Positive_regulation of Negative_regulation of Edn1 1 0.19 0.42 0.07
177 INT335129 PPARA Positive_regulation of Gene_expression of Insig1 1 0.20 0.15 0.07
178 INT172381 AVP Positive_regulation of Localization of EDN1 1 0.01 0.34 0.07
179 INT178096 EDN1 Positive_regulation of Gene_expression of EDNRB 1 0.17 1.01 0.07
180 INT181645 Edn1 Positive_regulation of NOS3 1 0.02 0.21 0.07
181 INT345297 Binding of NAGLU and Lcn2 1 0.01 1.24 0.07
182 INT178090 EDN1 Positive_regulation of Phosphorylation of GJA1 1 0.09 0.88 0.06
183 INT191216 Binding of Edn1 and Cotl1 1 0.14 0.63 0.05
184 INT182259 EDN1 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.27 0.05
185 INT287223 Pdx1 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
186 INT180668 Edn1 Positive_regulation of Gene_expression of Col1a1 1 0.02 0 0.05
187 INT287222 Cytip Regulation of Transcription of Insig1 1 0.02 0.56 0.05
188 INT182264 EDN1 Positive_regulation of Positive_regulation of MAPK14 1 0.26 0.1 0.05
189 INT214146 Msx1 Positive_regulation of Gene_expression of Nucb2 1 0.05 0.19 0.05
190 INT195221 Binding of CSRP1 and NAGLU 1 0.17 0.25 0.05
191 INT287221 Tcf3 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
192 INT180667 Edn1 Regulation of Ecm1 1 0.04 0 0.05
193 INT213263 INS Positive_regulation of EDN1 1 0.12 0.54 0.04
194 INT178091 EDN1 Positive_regulation of Gene_expression of PTGER2 1 0.01 0.74 0.04
195 INT253023 Binding of PTTG1 and Myc 1 0.16 0.22 0.04
196 INT353314 Edn1 Positive_regulation of Kalrn 1 0.03 0.21 0.04
197 INT229371 Positive_regulation of Pparg Negative_regulation of Gene_expression of Edn1 1 0.01 0.92 0.04
198 INT178098 EDN1 Positive_regulation of Transcription of VEGFA 1 0.08 0.76 0.04
199 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04
200 INT335017 Fgf23 Positive_regulation of Fgfr1 1 0.23 0.59 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported for middle ear morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in middle ear morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
2 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
3 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
4 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
5 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
6 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
7 INT5048 Binding of Edn1 55 0.47 18.86 19.16
8 INT9191 Localization of EDN1 94 0.81 57.01 14.78
9 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
10 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
11 INT6365 Localization of Edn1 56 0.81 18.84 13.83
12 INT10585 Localization of NAGLU 53 0.80 23.32 12.75
13 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
14 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
15 INT6361 Localization of Edn1 30 0.81 19.09 9.7
16 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
17 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
18 INT10237 Binding of EDN1 40 0.48 16 8.48
19 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
20 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
21 INT1973 Positive_regulation of NAGLU 36 0.65 14.78 7
22 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82
23 INT3163 Gene_expression of NAGLU 28 0.75 15.23 4.98
24 INT17803 Regulation of Edn1 14 0.54 4.75 4.71
25 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
26 INT14619 Positive_regulation of Localization of NAGLU 18 0.62 7.73 3.94
27 INT109391 Gene_expression of Fgfr1 7 0.56 1.78 3.67
28 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
29 INT119218 Positive_regulation of Fgfr1 4 0.58 1.11 3.05
30 INT53374 Binding of Edn1 17 0.43 11.66 2.98
31 INT36886 Transcription of Myc 6 0.69 3.16 2.86
32 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
33 INT73460 Positive_regulation of Gene_expression of Myc 26 0.67 20.44 2.61
34 INT32920 Gene_expression of Msx1 19 0.71 4.24 2.42
35 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
36 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
37 INT184676 Transcription of Prrx2 1 0.37 3.64 2.02
38 INT38008 Positive_regulation of Gene_expression of NAGLU 6 0.44 6.64 2
39 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
40 INT76834 Negative_regulation of Gene_expression of Edn1 4 0.43 1.76 1.88
41 INT194074 Regulation of NAGLU 5 0.38 2.93 1.87
42 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
43 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76
44 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
45 INT14842 Negative_regulation of Binding of EDN1 4 0.57 0.67 1.66
46 INT58931 Binding of NAGLU 11 0.34 4.47 1.63
47 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
48 INT184683 Gene_expression of Prrx2 1 0.37 7.9 1.5
49 INT15407 Positive_regulation of Positive_regulation of Edn1 5 0.62 3.69 1.49
50 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
51 INT65640 Positive_regulation of Localization of Edn1 2 0.42 2.16 1.48
52 INT270631 Gene_expression of Insig1 15 0.32 5.19 1.43
53 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36
54 INT116265 Binding of Myc 9 0.36 4.28 1.36
55 INT138726 Positive_regulation of Gene_expression of Msx1 5 0.53 1.73 1.2
56 INT17802 Transcription of Edn1 6 0.24 6.31 1.18
57 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12
58 INT71848 Positive_regulation of Transcription of Myc 1 0.67 0.16 1.11
59 INT184698 Positive_regulation of Prrx2 1 0.38 3.21 1.01
60 INT69803 Regulation of Localization of Edn1 3 0.62 0.79 0.98
61 INT102070 Regulation of Gene_expression of Myc 4 0.60 2.68 0.96
62 INT49255 Protein_catabolism of EDN1 5 0.99 2.66 0.95
63 INT69422 Positive_regulation of Negative_regulation of EDN1 2 0.43 0.96 0.95
64 INT49254 Transcription of EDN1 5 0.69 2.42 0.94
65 INT17894 Regulation of Myc 10 0.60 5.65 0.93
66 INT152081 Phosphorylation of Edn1 1 0.53 0.39 0.9
67 INT61591 Negative_regulation of Localization of EDN1 11 0.59 2.09 0.85
68 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82
69 INT57433 Positive_regulation of Binding of EDN1 3 0.49 0.62 0.82
70 INT61121 Regulation of Regulation of Edn1 1 0.43 0.2 0.75
71 INT95617 Regulation of Msx1 2 0.56 1.05 0.73
72 INT217098 Gene_expression of Hoxa2 1 0.77 2.23 0.72
73 INT59970 Positive_regulation of Binding of Edn1 2 0.40 1.11 0.71
74 INT166537 Localization of Fgfr1 5 0.40 2.69 0.69
75 INT21957 Negative_regulation of Negative_regulation of Edn1 5 0.43 1.34 0.69
76 INT49252 Positive_regulation of Localization of EDN1 17 0.69 6.55 0.66
77 INT100396 Transcription of Edn1 7 0.69 2.48 0.66
78 INT173508 Negative_regulation of Fgfr1 4 0.55 5.08 0.66
79 INT75043 Binding of Msx1 6 0.35 2.36 0.65
80 INT49256 Regulation of Positive_regulation of EDN1 2 0.45 2.5 0.65
81 INT146775 Phosphorylation of Fgfr1 1 0.53 0.8 0.62
82 INT150949 Gene_expression of Fgfr1 6 0.63 5.71 0.57
83 INT32921 Positive_regulation of Msx1 4 0.47 0.99 0.57
84 INT7153 Positive_regulation of Regulation of Edn1 2 0.35 1.97 0.57
85 INT135715 Negative_regulation of Localization of Edn1 5 0.42 1.7 0.56
86 INT63910 Regulation of Positive_regulation of Edn1 2 0.43 0.64 0.54
87 INT131641 Negative_regulation of Negative_regulation of Edn1 1 0.37 0.31 0.52
88 INT156254 Gene_expression of Six1 7 0.67 1.52 0.51
89 INT181581 Regulation of Positive_regulation of Edn1 4 0.23 3.76 0.51
90 INT62104 Localization of INSIG2 1 0.01 0 0.5
91 INT146776 Transcription of Fgfr1 1 0.45 0.67 0.49
92 INT146777 Regulation of Transcription of Fgfr1 1 0.23 0.67 0.49
93 INT55372 Regulation of Localization of Edn1 2 0.38 0.64 0.46
94 INT57434 Regulation of Regulation of EDN1 1 0.40 0.47 0.44
95 INT159221 Negative_regulation of TBX1 4 0.41 4.22 0.43
96 INT188371 Regulation of Localization of Fgfr1 1 0.10 1.02 0.43
97 INT247307 Negative_regulation of Msx1 3 0.22 0.11 0.42
98 INT47915 Negative_regulation of NAGLU 2 0.22 0.66 0.42
99 INT65606 Binding of TBX1 2 0.30 3.13 0.41
100 INT90354 Negative_regulation of Myc 6 0.57 4.24 0.4
101 INT81433 Negative_regulation of Positive_regulation of Edn1 4 0.39 0.81 0.38
102 INT113368 Regulation of Negative_regulation of Edn1 1 0.45 0.71 0.35
103 INT141013 Regulation of Gene_expression of Edn1 2 0.24 0.55 0.34
104 INT281177 Regulation of Insig1 2 0.25 0.93 0.33
105 INT150948 Positive_regulation of Gene_expression of Fgfr1 3 0.15 3.19 0.32
106 INT16368 Protein_catabolism of Edn1 2 0.72 0.18 0.31
107 INT297865 Positive_regulation of Gene_expression of Insig1 2 0.21 0.4 0.28
108 INT269082 Gene_expression of TBX1 1 0.14 0.36 0.28
109 INT180696 Positive_regulation of Gene_expression of Fgfr1 1 0.32 0.08 0.28
110 INT214128 Negative_regulation of Gene_expression of Msx1 3 0.53 1.25 0.26
111 INT84038 Protein_catabolism of Edn1 2 0.86 0.69 0.26
112 INT187547 Localization of Myc 1 0.68 0.92 0.26
113 INT187548 Regulation of Transcription of Myc 1 0.44 0.68 0.26
114 INT172445 Positive_regulation of Gene_expression of Myc 58 0.70 39.62 0.25
115 INT285474 Negative_regulation of Gene_expression of Fgfr1 2 0.40 2.15 0.24
116 INT184670 Localization of Prrx2 1 0.35 0.23 0.24
117 INT26879 Positive_regulation of Positive_regulation of NAGLU 1 0.54 0.15 0.24
118 INT184671 Positive_regulation of Localization of Prrx2 1 0.24 0.23 0.24
119 INT306427 Localization of TBX1 1 0.20 1.08 0.23
120 INT306428 Positive_regulation of Localization of TBX1 1 0.14 1.08 0.23
121 INT102071 Negative_regulation of Gene_expression of Myc 8 0.57 3.5 0.22
122 INT262077 Positive_regulation of Insig1 3 0.29 0.34 0.21
123 INT270625 Regulation of Gene_expression of Insig1 2 0.19 1.4 0.21
124 INT188373 Positive_regulation of Localization of Fgfr1 1 0.19 1.09 0.21
125 INT297868 Regulation of Regulation of Insig1 1 0.11 0.82 0.21
126 INT67265 Positive_regulation of Negative_regulation of Edn1 1 0.61 0.05 0.21
127 INT115158 Gene_expression of INSIG2 1 0.01 0.33 0.21
128 INT173515 Negative_regulation of Transcription of Fgfr1 1 0.06 0.92 0.21
129 INT303539 Binding of Fgfr1 3 0.45 0.96 0.2
130 INT173503 Transcription of Fgfr1 1 0.08 0.92 0.2
131 INT156920 Phosphorylation of EDN1 4 0.61 0.66 0.19
132 INT53372 Positive_regulation of Regulation of Edn1 1 0.50 0 0.19
133 INT100397 Regulation of Transcription of Edn1 1 0.00 0.1 0.19
134 INT184674 Negative_regulation of Prrx2 1 0.23 3.14 0.14
135 INT214127 Localization of Msx1 1 0.06 0.21 0.13
136 INT323417 Protein_catabolism of Osr1 1 0.07 0.84 0.13
137 INT284152 Regulation of Transcription of EDN1 1 0.32 0.44 0.13
138 INT6362 Negative_regulation of Localization of Edn1 3 0.16 1.92 0.12
139 INT162568 Regulation of TBX1 3 0.35 1.54 0.11
140 INT258933 Protein_catabolism of TBX1 1 0.43 0.75 0.11
141 INT261711 Binding of GSC 1 0.32 0 0.11
142 INT179083 Positive_regulation of Myc 65 0.70 38.78 0.1
143 INT15391 Negative_regulation of Positive_regulation of Edn1 2 0.07 0.1 0.1
144 INT170744 Positive_regulation of Transcription of Edn1 2 0.20 1.3 0.1
145 INT217092 Positive_regulation of Hoxa2 1 0.69 0.13 0.1
146 INT184669 Positive_regulation of Transcription of Prrx2 1 0.27 2.71 0.1
147 INT188374 Negative_regulation of Fgfr1 1 0.22 0.68 0.1
148 INT172453 Binding of Myc 6 0.48 2.36 0.08
149 INT49257 Positive_regulation of Transcription of EDN1 2 0.46 1.1 0.08
150 INT126441 Negative_regulation of Transcription of Edn1 1 0.40 0.17 0.08
151 INT250851 Binding of Fgfr1 1 0.10 0.19 0.08
152 INT184689 Regulation of Prrx2 1 0.13 0.77 0.08
153 INT179085 Regulation of Myc 6 0.28 2.83 0.06
154 INT17893 Positive_regulation of Myc 4 0.67 3.28 0.06
155 INT188372 Negative_regulation of Localization of Fgfr1 1 0.22 0.66 0.06
156 INT287201 Transcription of Insig1 2 0.29 2.87 0.05
157 INT201778 Positive_regulation of Phosphorylation of Myc 1 0.49 1.02 0.05
158 INT208924 Gene_expression of Eya1 1 0.34 0.33 0.05
159 INT201776 Phosphorylation of Myc 1 0.80 1.01 0.05
160 INT178299 Transcription of Myc 4 0.63 0.82 0.04
161 INT178287 Positive_regulation of Transcription of Myc 2 0.47 0.49 0.04
162 INT178288 Regulation of Transcription of Myc 1 0.19 0.14 0.04
163 INT184682 Negative_regulation of Gene_expression of Prrx2 1 0.23 1.5 0.04
164 INT217087 Binding of Hoxa2 1 0.48 0.25 0.04
165 INT332334 Regulation of Binding of Myc 1 0.44 0 0.04
166 INT303538 Positive_regulation of Fgfr1 3 0.65 0.92 0.03
167 INT179080 Positive_regulation of Positive_regulation of Myc 1 0.70 5.2 0.03
168 INT303544 Positive_regulation of Negative_regulation of Fgfr1 1 0.47 1.07 0.03
169 INT217105 Negative_regulation of Hoxa2 1 0.58 0.21 0.03
170 INT261706 Regulation of Binding of GSC 1 0.34 0 0.03
171 INT323421 Gene_expression of Osr1 1 0.05 0.46 0.03
172 INT303536 Localization of Fgfr1 1 0.70 0.28 0.03
173 INT179078 Regulation of Gene_expression of Myc 6 0.62 3.02 0
174 INT179079 Negative_regulation of Myc 3 0.37 1.92 0
175 INT179077 Negative_regulation of Gene_expression of Myc 3 0.59 1.36 0
176 INT261713 Regulation of GSC 2 0.34 0.91 0
177 INT179081 Negative_regulation of Positive_regulation of Myc 2 0.37 1.27 0
178 INT272974 Negative_regulation of Gene_expression of Osr1 1 0.04 1.58 0
179 INT310246 Positive_regulation of Positive_regulation of Fgfr1 1 0.31 0 0
180 INT142711 Negative_regulation of Transcription of Myc 1 0.41 0.45 0
181 INT260509 Localization of Myc 1 0.60 0.35 0
182 INT217084 Regulation of Hoxa2 1 0.45 0.07 0
183 INT179075 Positive_regulation of Binding of Myc 1 0.50 0.14 0
184 INT217089 Regulation of Gene_expression of Hoxa2 1 0.45 0.66 0
185 INT217081 Positive_regulation of Gene_expression of Hoxa2 1 0.50 0.19 0
186 INT213510 Localization of Eya1 1 0.65 0 0
187 INT262064 Negative_regulation of Positive_regulation of Insig1 1 0.09 0.05 0
188 INT280682 Positive_regulation of Transcription of Edn1 1 0.34 0 0
189 INT49261 Negative_regulation of Protein_catabolism of EDN1 1 0.58 0 0
190 INT314739 Transcription of TBX1 1 0.32 0.8 0
191 INT217099 Negative_regulation of Gene_expression of Hoxa2 1 0.58 0.06 0
192 INT272976 Regulation of Osr1 1 0.04 1.54 0
193 INT297864 Positive_regulation of Transcription of Insig1 1 0.21 2.31 0
194 INT213525 Regulation of Localization of Eya1 1 0.39 0 0
195 INT272973 Gene_expression of Osr1 1 0.06 5.27 0
196 INT180708 Regulation of Fgfr1 1 0.09 0 0
197 INT172440 Negative_regulation of Binding of Myc 1 0.15 0.55 0
198 INT179087 Regulation of Positive_regulation of Myc 1 0.45 0.8 0
199 INT272975 Negative_regulation of Osr1 1 0.05 1.51 0
200 INT223093 Phosphorylation of NAGLU 1 0.45 0.95 0
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