GO:0042475

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Name odontogenesis of dentin-containing tooth
Categary Process
Go Slim No
Go Link GO:0042475
Unique Molecular Interactions 890
Total Molecular Interactions 1109
Total Single Events 8979
Pain Genes Associated 79

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for odontogenesis of dentin-containing tooth. They are ordered first by their pain relevance and then by number of times they were reported for odontogenesis of dentin-containing tooth. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
2 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13
3 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72
4 INT187175 Binding of BSG and PPIA 1 0.14 2.23 1.64
5 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55
6 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
7 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49
8 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
9 INT136644 T(1;9)27H Negative_regulation of Gene_expression of Hand1 1 0.15 1.14 1.27
10 INT285185 Binding of Ca2 and Cd2 1 0.25 0.24 1.21
11 INT110435 Positive_regulation of Grm8 Positive_regulation of Localization of Ca2 1 0.38 0 1.21
12 INT280949 Binding of Fst and Inhbe 3 0.01 2.51 1.15
13 INT187176 Binding of BSG and MMP1 1 0.09 1.18 1.08
14 INT167819 IFNA1 Positive_regulation of Fst 1 0.39 0 1.07
15 INT146897 Binding of Fst and OR13H1 1 0.01 0 1.05
16 INT293014 IRF6 Positive_regulation of Localization of CA2 1 0.04 0.71 1.02
17 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01
18 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
19 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99
20 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99
21 INT228495 Il13 Negative_regulation of Hand1 1 0.01 1.4 0.98
22 INT69506 CA2 Positive_regulation of PRKCA 1 0.50 0.42 0.98
23 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
24 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
25 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
26 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
27 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
28 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
29 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
30 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
31 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
32 INT197470 Binding of Sostdc1 and Hbtq 1 0.00 0.87 0.87
33 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
34 INT190168 BSG Regulation of CDCP1 1 0.00 1.18 0.84
35 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
36 INT257895 Positive_regulation of Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83
37 INT257896 Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83
38 INT270217 Binding of C2 and Ca2 1 0.03 1.63 0.81
39 INT251172 Trpv1 Regulation of Gene_expression of Ca2 1 0.13 0.7 0.81
40 INT140922 Btnl2 Negative_regulation of EDA 1 0.00 0.88 0.8
41 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
42 INT132894 CHUK Regulation of Gene_expression of Nos2 1 0.00 0.21 0.79
43 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
44 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
45 INT346133 RAMP2 Regulation of ADM 1 0.13 2.06 0.78
46 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
47 INT136795 Spp1 Positive_regulation of Chuk 1 0.11 1.54 0.77
48 INT64067 Tp63 Negative_regulation of Localization of Gh1 1 0.08 0.07 0.76
49 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75
50 INT98770 Binding of Dll1 and Gt(pU21)50Imeg 1 0.05 0 0.74
51 INT75399 Regulation of Binding of Dll1 and Oprd1 1 0.08 0 0.74
52 INT98771 Binding of Dll1 and Oprm1 1 0.29 0 0.74
53 INT75398 Binding of Dll1 and Oprd1 1 0.11 0 0.74
54 INT111080 Binding of CA1 and CA2 2 0.02 1.62 0.73
55 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
56 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72
57 INT126598 Binding of BSG and OPRK1 1 0.01 0.05 0.72
58 INT101675 Bcl2l11 Regulation of Localization of Ggh 1 0.03 0 0.72
59 INT272147 PTAFR Positive_regulation of CA2 1 0.13 0 0.71
60 INT208978 Ca2 Positive_regulation of Trpv1 1 0.22 0.29 0.71
61 INT251169 Clu Regulation of Ca2 1 0.03 0.66 0.7
62 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69
63 INT64070 Tp63 Regulation of Ghrh 1 0.04 0.06 0.69
64 INT64068 Tp63 Regulation of Fdft1 1 0.00 0.06 0.69
65 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
66 INT137102 Fst Regulation of Sec22b 1 0.07 0 0.67
67 INT137101 Fst Regulation of Htr1a 1 0.24 0 0.67
68 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
69 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
70 INT251165 Trpv1 Positive_regulation of Gene_expression of Ca2 1 0.15 0.54 0.65
71 INT27526 Binding of Sdcbp and Eda 1 0.13 0 0.65
72 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
73 INT190211 Adm Regulation of MMP12 1 0.29 0 0.65
74 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
75 INT352462 Gse1 Positive_regulation of Gene_expression of Tnc 1 0.05 0.75 0.64
76 INT235082 CA2 Positive_regulation of NOS1 2 0.11 0.62 0.63
77 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
78 INT50816 Penk Positive_regulation of Localization of Ca2 1 0.32 0 0.62
79 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
80 INT352459 Gse1 Regulation of Gene_expression of Tnc 1 0.05 0 0.6
81 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
82 INT70254 Binding of Htr1a and Ca2 1 0.31 0.5 0.6
83 INT144320 Binding of Fst and Rbm39 1 0.04 0 0.59
84 INT275063 CA2 Positive_regulation of Positive_regulation of CAMK4 1 0.01 0 0.59
85 INT240070 KCNIP3 Regulation of CA2 1 0.02 0.72 0.59
86 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57
87 INT112025 Binding of Hand1 and Il10 2 0.15 0.56 0.55
88 INT355881 Il17a Regulation of Gene_expression of Hand1 1 0.18 1.51 0.54
89 INT208984 Binding of Ca2 and Fig4 1 0.02 0 0.54
90 INT108441 Adm Positive_regulation of Sst 1 0.40 0 0.54
91 INT216918 Binding of Ca2 and Abat 1 0.01 0.45 0.53
92 INT118138 Binding of Ca2 and Mgat4a 1 0.01 0 0.53
93 INT330544 Bcl2l11 Negative_regulation of Prkcg 1 0.03 0.38 0.52
94 INT330553 Bcl2l11 Negative_regulation of Camk2a 1 0.01 0.38 0.52
95 INT330541 Bcl2l11 Negative_regulation of Negative_regulation of Prkcg 1 0.03 0.38 0.52
96 INT330545 Bcl2l11 Negative_regulation of Trib3 1 0.00 0.38 0.52
97 INT297479 Ryr2 Positive_regulation of Ca2 1 0.22 0 0.52
98 INT346146 ADM Positive_regulation of Gene_expression of PERP 1 0.02 1.54 0.51
99 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
100 INT318472 CA2 Regulation of OPRM1 1 0.17 0 0.51
101 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
102 INT330796 P2ry1 Positive_regulation of Ca2 1 0.05 0.06 0.5
103 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
104 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48
105 INT250077 Positive_regulation of Ltp Positive_regulation of Localization of Ca2 1 0.10 0 0.48
106 INT145954 Binding of BSG and MME 1 0.00 0.81 0.47
107 INT141964 Binding of ADM and RAMP1 1 0.30 2.63 0.47
108 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46
109 INT92743 Binding of NF2 and LMOD1 1 0.00 0.08 0.46
110 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
111 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46
112 INT275550 Hand1 Positive_regulation of Localization of Hand2 1 0.00 1.29 0.46
113 INT108440 Adm Regulation of Localization of Sst 1 0.41 0 0.45
114 INT259208 Ca2 Positive_regulation of Phosphorylation of Creb1 1 0.04 0 0.45
115 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
116 INT355540 Gnptg Positive_regulation of AMELX 1 0.00 2.16 0.44
117 INT254460 Binding of Calm2 and Ca2 5 0.03 0.48 0.43
118 INT302369 Binding of Arx and Dlx1 1 0.34 0 0.43
119 INT48038 Adm Regulation of Calca 1 0.31 0.14 0.42
120 INT92744 Binding of ADRB2 and NF2 1 0.00 0.1 0.41
121 INT116938 Positive_regulation of GLI2 Positive_regulation of MAPK8 1 0.10 0.07 0.41
122 INT346151 Binding of ADM and GPER 1 0.01 0.99 0.41
123 INT116936 Positive_regulation of GLI2 Positive_regulation of JUN 1 0.12 0.07 0.41
124 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
125 INT346150 Binding of ADM and FN1 1 0.10 0.93 0.39
126 INT346140 Positive_regulation of Binding of ADM and MMRN1 1 0.04 0.93 0.39
127 INT346139 Binding of ADM and MMRN1 1 0.03 0.93 0.39
128 INT346135 Positive_regulation of Binding of ADM and FN1 1 0.13 0.93 0.39
129 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
130 INT15028 NA Positive_regulation of Localization of Ca2 1 0.04 0 0.39
131 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
132 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
133 INT272148 PTAFR Regulation of Localization of CA2 1 0.14 0 0.38
134 INT339506 Binding of Irak1 and Traf6 1 0.03 0.12 0.37
135 INT235083 CA2 Positive_regulation of Gene_expression of CALM1 1 0.01 0.63 0.37
136 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
137 INT60817 Binding of Sstr1 and Bcl2l11 1 0.06 0 0.37
138 INT33862 Ca2 Positive_regulation of Positive_regulation of Sult1b1 1 0.07 0.07 0.37
139 INT320591 Ca2 Positive_regulation of Nos1 1 0.07 0.09 0.37
140 INT263226 Prkcg Negative_regulation of Positive_regulation of Ca2 1 0.01 0.58 0.36
141 INT305853 Polk Regulation of Gene_expression of Hand2 1 0.12 0.93 0.35
142 INT346145 Binding of ADM and TPX2 1 0.01 1.05 0.35
143 INT302371 Dlx1 Regulation of Gene_expression of Arx 1 0.28 0 0.35
144 INT168202 Msx1 Negative_regulation of Gene_expression of Mc1r 1 0.21 0.49 0.35
145 INT190173 BSG Regulation of MMRN1 1 0.00 0.29 0.35
146 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
147 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
148 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34
149 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
150 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
151 INT324690 Binding of Traf6 and Ticam1 2 0.07 0.23 0.33
152 INT112024 Binding of Hand1 and Ighg1 2 0.30 0.84 0.33
153 INT353689 Binding of Slc8a1 and Ca2 1 0.15 0.58 0.33
154 INT241966 Binding of Ca2 and Acpt 1 0.06 0.06 0.33
155 INT322129 Binding of Prkcg and Ca2 1 0.00 0.57 0.33
156 INT322133 Trpv4 Regulation of Ca2 1 0.04 0.16 0.33
157 INT34449 Binding of Ca2 and Pck1 1 0.17 0.18 0.33
158 INT112018 Binding of Hand1 and IgG2a 2 0.22 0.84 0.32
159 INT266806 Hand2 Regulation of Gene_expression of IL10 1 0.00 1.23 0.32
160 INT241139 Ighg1 Positive_regulation of Hand2 1 0.06 0.65 0.32
161 INT189494 Negative_regulation of Ccr5 Negative_regulation of Gene_expression of Hand1 1 0.16 0.66 0.32
162 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32
163 INT112022 Binding of Hand1 and Ifng 1 0.09 0.3 0.32
164 INT241138 Ighg1 Positive_regulation of Hand1 1 0.06 0.64 0.32
165 INT203089 Binding of Il1a and Traf6 1 0.04 0.66 0.32
166 INT181433 Hand2 Regulation of Gene_expression of Ccl2 1 0.12 0.68 0.32
167 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 0.02 0.21 0.32
168 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
169 INT195146 Cpm Regulation of Localization of CA2 1 0.00 0.22 0.32
170 INT203086 Positive_regulation of Binding of Il1a and Traf6 1 0.06 0.67 0.32
171 INT266804 Hand2 Regulation of Gene_expression of IL13 1 0.00 1.23 0.32
172 INT266805 Hand2 Regulation of Gene_expression of IL4 1 0.00 1.23 0.32
173 INT188707 Binding of IFNA1 and Hand1 1 0.01 0.56 0.32
174 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
175 INT241971 Ca2 Regulation of Localization of Abat 1 0.01 0 0.31
176 INT253073 Il4 Positive_regulation of Hand2 1 0.10 0.59 0.31
177 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3
178 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
179 INT243631 Binding of Hand1 and Nfatc1 1 0.04 0.76 0.3
180 INT156261 Negative_regulation of Binding of Oxt and Ca2 1 0.16 0.12 0.3
181 INT26738 Ca2 Positive_regulation of Localization of Ins1 1 0.12 0.09 0.3
182 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
183 INT93988 Rab8a Regulation of Hand2 1 0.09 0.78 0.3
184 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
185 INT261047 MZB1 Positive_regulation of Positive_regulation of CA2 1 0.02 0.09 0.3
186 INT156262 Binding of Oxt and Ca2 1 0.14 0.12 0.3
187 INT334499 Binding of AMELX and IL4 1 0.12 0.47 0.29
188 INT254206 Il10 Negative_regulation of Chuk 1 0.05 0.59 0.29
189 INT252604 Negative_regulation of Cxcl10 Negative_regulation of Gene_expression of Hand1 1 0.24 0.5 0.29
190 INT181442 Ccl2 Positive_regulation of Localization of Hand2 1 0.26 0.63 0.29
191 INT75056 Binding of MC1R and Msx1 1 0.00 0.17 0.29
192 INT254208 Il10 Negative_regulation of Regulation of Chuk 1 0.05 0.59 0.29
193 INT324801 Positive_regulation of Binding of Chuk and Irak1 1 0.03 0.86 0.28
194 INT185076 Bpifa2 Positive_regulation of Hand2 1 0.16 0.36 0.28
195 INT278209 Ciita Regulation of Hand2 1 0.36 1.53 0.28
196 INT324825 Binding of Chuk and Myd88 1 0.03 0.86 0.28
197 INT324810 Binding of Chuk and Irak1 1 0.02 0.85 0.28
198 INT352452 Calca Regulation of Gene_expression of Tnc 1 0.04 0 0.28
199 INT194821 MAPK1 Regulation of Hand2 1 0.03 1.27 0.28
200 INT214615 FOXC1 Positive_regulation of Gene_expression of Ang 1 0.01 0.29 0.28

Single Events

The table below shows the top 100 pain related interactions that have been reported for odontogenesis of dentin-containing tooth. They are ordered first by their pain relevance and then by number of times they were reported in odontogenesis of dentin-containing tooth. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64
2 INT4822 Localization of Ca2 417 0.80 99.57 96.45
3 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71
4 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01
5 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53
6 INT1032 Regulation of Ca2 202 0.52 54.91 53.03
7 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
8 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97
9 INT5489 Localization of CA2 172 0.80 39.46 33.56
10 INT16290 Gene_expression of BSG 60 0.68 38.73 32.86
11 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
12 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
13 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4
14 INT14546 Positive_regulation of Localization of Ca2 93 0.67 31.09 18.72
15 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
16 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96
17 INT104045 Regulation of Hand1 65 0.35 51.32 16.26
18 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
19 INT113625 Positive_regulation of Gene_expression of Ca2 47 0.50 9.82 14.07
20 INT50056 Positive_regulation of Dll1 13 0.67 3.16 13.7
21 INT173505 Localization of Hand2 63 0.57 45.32 13.66
22 INT20378 Localization of Hand1 53 0.71 41.96 13.31
23 INT19799 Binding of Ca2 71 0.48 13.69 12.92
24 INT94464 Negative_regulation of Hand1 44 0.41 31.5 12.39
25 INT11793 Negative_regulation of CA2 78 0.57 19.63 12.35
26 INT32054 Gene_expression of Tnc 14 0.59 9.36 12.22
27 INT65277 Negative_regulation of Fst 20 0.43 4.61 11.83
28 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64
29 INT94465 Positive_regulation of Gene_expression of Hand1 43 0.38 29.76 10.88
30 INT3535 Regulation of CA2 61 0.32 16.48 10.8
31 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
32 INT33094 Regulation of Localization of Ca2 28 0.38 8.65 9.96
33 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
34 INT23535 Positive_regulation of Localization of CA2 41 0.41 13.52 9.43
35 INT23094 Positive_regulation of Positive_regulation of Ca2 29 0.49 6.8 9.35
36 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
37 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28
38 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24
39 INT56019 Gene_expression of Dll1 11 0.78 3.38 8.71
40 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37
41 INT70572 Gene_expression of Fst 33 0.78 5.22 8.24
42 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
43 INT60931 Negative_regulation of Fst 15 0.57 5.44 7.21
44 INT58607 Negative_regulation of Dll1 9 0.43 1.89 7.06
45 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01
46 INT4431 Negative_regulation of Eda 10 0.46 3.53 6.81
47 INT19366 Negative_regulation of Localization of Ca2 33 0.50 6.51 6.61
48 INT195145 Positive_regulation of Gene_expression of CA2 25 0.37 7.2 6.59
49 INT70287 Positive_regulation of Gene_expression of Dll1 6 0.70 3.58 6.55
50 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
51 INT86060 Positive_regulation of Fst 13 0.64 3.04 6.33
52 INT185252 Gene_expression of Dlx2 7 0.71 8.8 6.24
53 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13
54 INT333909 Positive_regulation of Gene_expression of HDAC1 1 0.44 14.15 5.9
55 INT113700 Positive_regulation of Chuk 30 0.41 21.17 5.69
56 INT4938 Localization of Tnc 5 0.65 1.73 5.64
57 INT5490 Binding of CA2 52 0.36 9.73 5.53
58 INT149739 Regulation of Gene_expression of Ca2 25 0.38 7.22 5.53
59 INT51411 Negative_regulation of EDAR 8 0.41 1.05 5.49
60 INT145929 Regulation of Bax 20 0.60 18.12 5.35
61 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
62 INT141275 Negative_regulation of Gene_expression of Hand1 18 0.34 15.83 5.05
63 INT65276 Gene_expression of Fst 12 0.65 4.99 5.05
64 INT6983 Negative_regulation of Positive_regulation of Ca2 18 0.41 4.29 5.03
65 INT187189 Positive_regulation of Gene_expression of BSG 1 0.61 6.21 5.02
66 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
67 INT197458 Positive_regulation of Sostdc1 11 0.01 3.02 4.87
68 INT79194 Positive_regulation of Tnc 5 0.41 2.25 4.69
69 INT94466 Regulation of Gene_expression of Hand2 14 0.28 7.97 4.46
70 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
71 INT56404 Gene_expression of EDA 16 0.75 7.09 4.24
72 INT70756 Gene_expression of Adm 28 0.77 13.33 4.22
73 INT32053 Positive_regulation of Gene_expression of Tnc 5 0.45 3.4 4.13
74 INT197459 Gene_expression of Sostdc1 10 0.01 1.04 4.11
75 INT151736 Binding of Hand1 15 0.26 9.77 4.04
76 INT123752 Regulation of Bax 19 0.60 16.45 4
77 INT64170 Gene_expression of GLI2 31 0.46 14.96 3.99
78 INT156131 Binding of Hand2 14 0.25 10.35 3.99
79 INT112692 Localization of Bax 31 0.80 20.97 3.98
80 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44
81 INT12844 Binding of TP63 15 0.47 10.57 3.38
82 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
83 INT49190 Regulation of Dll1 3 0.44 0.26 3.24
84 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
85 INT33237 Regulation of Fst 10 0.39 1.3 3
86 INT55148 Binding of Dll1 5 0.48 0.66 2.97
87 INT174958 Negative_regulation of Chuk 21 0.25 8.73 2.96
88 INT15549 Regulation of Positive_regulation of Ca2 11 0.38 2.55 2.92
89 INT91520 Negative_regulation of Positive_regulation of CA2 7 0.30 0.99 2.92
90 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
91 INT132773 Negative_regulation of Acvr2b 3 0.41 1.55 2.87
92 INT2042 Phosphorylation of Ca2 21 0.55 1.54 2.81
93 INT187187 Regulation of Gene_expression of BSG 3 0.40 3.84 2.8
94 INT72812 Positive_regulation of BSG 2 0.49 2.2 2.76
95 INT94463 Regulation of Gene_expression of Hand1 10 0.36 5.17 2.72
96 INT66891 Negative_regulation of Positive_regulation of Dll1 1 0.41 0 2.72
97 INT5460 Positive_regulation of EDAR 10 0.23 8.18 2.71
98 INT70253 Negative_regulation of Gene_expression of Ca2 29 0.49 16.31 2.69
99 INT222845 Gene_expression of Chuk 27 0.52 25.15 2.67
100 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55
101 INT93562 Negative_regulation of Localization of CA2 15 0.59 1.87 2.51
102 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
103 INT4939 Negative_regulation of Tnc 2 0.32 0.79 2.46
104 INT32920 Gene_expression of Msx1 19 0.71 4.24 2.42
105 INT59287 Positive_regulation of Eda 5 0.40 1.25 2.36
106 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
107 INT250727 Negative_regulation of ADM 3 0.38 8.32 2.26
108 INT132893 Binding of CHUK 1 0.00 0.63 2.25
109 INT74241 Positive_regulation of Gene_expression of EDA 3 0.49 4.93 2.24
110 INT163580 Positive_regulation of Fst 4 0.19 2.85 2.17
111 INT302340 Positive_regulation of Gene_expression of Dlx2 2 0.64 3.43 2.15
112 INT154970 Localization of Bax 15 0.74 11.12 2.11
113 INT72743 Positive_regulation of Negative_regulation of Ca2 4 0.49 1.41 2.11
114 INT228061 Positive_regulation of Localization of Hand1 8 0.26 6.39 2.06
115 INT112015 Negative_regulation of Regulation of Hand1 5 0.33 3.48 2.05
116 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
117 INT132892 Positive_regulation of CHUK 3 0.08 1.62 2.01
118 INT141968 Positive_regulation of ADM 12 0.65 11.19 2
119 INT43044 Gene_expression of Eda 3 0.75 0.69 2
120 INT138316 Regulation of Fst 5 0.44 1.15 1.99
121 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
122 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
123 INT98836 Transcription of Bax 6 0.69 5.04 1.96
124 INT228129 Negative_regulation of Bcl2l11 10 0.58 11.08 1.93
125 INT129239 Positive_regulation of Positive_regulation of Hand2 5 0.43 2.81 1.93
126 INT161432 Negative_regulation of Gene_expression of Tnc 2 0.38 1.44 1.93
127 INT107905 Gene_expression of BCL2L11 9 0.75 7.58 1.92
128 INT134442 Transcription of Bax 14 0.67 7.6 1.9
129 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
130 INT153684 Negative_regulation of Bcl2l11 3 0.31 1.19 1.89
131 INT134443 Binding of Bax 10 0.47 5.62 1.84
132 INT4188 Binding of NF2 7 0.46 3.52 1.79
133 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
134 INT90926 Positive_regulation of GLI2 12 0.45 4.99 1.74
135 INT24283 Regulation of Positive_regulation of CA2 8 0.30 3.06 1.74
136 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
137 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
138 INT102449 Binding of ADM 12 0.33 5.85 1.73
139 INT101707 Gene_expression of FGF4 9 0.78 3.99 1.73
140 INT64807 Positive_regulation of Positive_regulation of CA2 10 0.41 1.21 1.7
141 INT35325 Regulation of Localization of CA2 10 0.32 1.13 1.69
142 INT60815 Binding of Bcl2l11 2 0.27 0.95 1.67
143 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
144 INT26393 Localization of Eda 4 0.60 0.18 1.63
145 INT280933 Binding of Fst 4 0.12 3.53 1.63
146 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62
147 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
148 INT285510 Regulation of Localization of Hand1 6 0.14 6.13 1.61
149 INT132890 Positive_regulation of Binding of CHUK 1 0.00 0.44 1.6
150 INT132891 Gene_expression of CHUK 1 0.01 0.47 1.58
151 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57
152 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
153 INT19798 Positive_regulation of Binding of Ca2 2 0.41 1.37 1.54
154 INT272884 Gene_expression of Hdac2 19 0.43 14.55 1.48
155 INT119936 Transcription of Ca2 13 0.59 1.71 1.47
156 INT100672 Transcription of Hand2 9 0.42 2.84 1.47
157 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
158 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
159 INT140245 Binding of Gli3 3 0.36 2.65 1.46
160 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
161 INT49402 Positive_regulation of EDA 6 0.61 4.23 1.43
162 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
163 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38
164 INT333914 Transcription of HDAC1 1 0.34 3.04 1.37
165 INT143716 Phosphorylation of Chuk 16 0.41 5.25 1.35
166 INT102228 Localization of Adm 9 0.69 1.58 1.34
167 INT169743 Regulation of Positive_regulation of Adm 1 0.37 0.38 1.32
168 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
169 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
170 INT252389 Negative_regulation of Gene_expression of ADM 2 0.38 4.78 1.3
171 INT217438 Binding of Chuk 24 0.25 7.29 1.29
172 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
173 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
174 INT198840 Transcription of EDA 1 0.58 0.97 1.26
175 INT228128 Gene_expression of Bcl2l11 31 0.67 18.31 1.25
176 INT48037 Regulation of Adm 8 0.44 3.96 1.24
177 INT104839 Negative_regulation of GLI2 8 0.35 2.7 1.24
178 INT107904 Positive_regulation of Gene_expression of BCL2L11 3 0.53 2.22 1.24
179 INT4430 Regulation of Eda 2 0.23 0.38 1.24
180 INT133371 Negative_regulation of Binding of Dll1 1 0.41 0.5 1.22
181 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
182 INT298979 Gene_expression of Traf6 5 0.31 1.75 1.21
183 INT175452 Negative_regulation of Positive_regulation of Hand2 4 0.21 3.78 1.21
184 INT303667 Regulation of BCL2L11 3 0.16 1.03 1.21
185 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
186 INT138726 Positive_regulation of Gene_expression of Msx1 5 0.53 1.73 1.2
187 INT39711 Negative_regulation of FOXC1 4 0.41 4.29 1.2
188 INT141969 Positive_regulation of Gene_expression of ADM 4 0.57 4.07 1.2
189 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
190 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
191 INT81311 Gene_expression of FOXC1 9 0.44 3.46 1.18
192 INT272879 Negative_regulation of Hdac2 8 0.37 5.96 1.17
193 INT81757 Regulation of Gene_expression of Adm 6 0.44 2.86 1.16
194 INT54044 Negative_regulation of EDA 7 0.42 2.54 1.14
195 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
196 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
197 INT49536 Regulation of Regulation of Ca2 6 0.38 3.89 1.13
198 INT278117 Negative_regulation of TP63 5 0.32 3.38 1.13
199 INT23847 Phosphorylation of CA2 8 0.61 0.67 1.12
200 INT260447 Binding of HDAC1 8 0.23 4.47 1.12
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