GO:0042487

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Name regulation of odontogenesis of dentin-containing tooth
Categary Process
Go Slim No
Go Link GO:0042487
Unique Molecular Interactions 63
Total Molecular Interactions 99
Total Single Events 812
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of odontogenesis of dentin-containing tooth. They are ordered first by their pain relevance and then by number of times they were reported for regulation of odontogenesis of dentin-containing tooth. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
2 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
3 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
4 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
5 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
6 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
7 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
8 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
9 INT330519 Binding of CD8A and DICER1 1 0.08 0.99 0.38
10 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
11 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
12 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
13 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
14 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
15 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
16 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
17 INT277613 Binding of HDAC9 and Runx2 1 0.02 0.59 0.26
18 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
19 INT350711 Ifnb1 Negative_regulation of Gene_expression of DICER1 1 0.03 0.15 0.14
20 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
21 INT223963 Binding of Bglap and Runx2 1 0.14 1.74 0.13
22 INT311905 Binding of Runx2 and Smad1 1 0.12 0.46 0.13
23 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
24 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
25 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
26 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
27 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09
28 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
29 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
30 INT297968 Positive_regulation of Binding of BMP2 and IL17C 1 0.21 0.26 0.08
31 INT297970 Binding of BMP2 and IL17C 1 0.15 0.26 0.08
32 INT322560 Binding of TNFSF10 and DICER1 1 0.07 1.76 0.07
33 INT295122 Bmp2 Regulation of Grxcr1 1 0.02 0.66 0.06
34 INT295120 Bmp2 Regulation of Transcription of Pou1f1 1 0.24 0.66 0.06
35 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
36 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
37 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 0.64 0 0.05
38 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03
39 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
40 INT287233 PDLIM7 Positive_regulation of Gene_expression of BMP2 1 0.07 0.12 0.03
41 INT343999 INCENP Positive_regulation of BMP2 1 0.01 0 0
42 INT352148 Ift88 Negative_regulation of Bcl2l2 1 0.00 0.19 0
43 INT278021 BMP2 Positive_regulation of Gene_expression of RUNX1T1 1 0.02 0.5 0
44 INT205451 Binding of BMP2 and Acvr2a 1 0.02 0.05 0
45 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
46 INT205410 Binding of BMP2 and BMPR2 1 0.07 0.05 0
47 INT344001 INCENP Positive_regulation of Gene_expression of BMP2 1 0.01 0 0
48 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
49 INT295129 Proc Regulation of Bmp2 1 0.00 0.48 0
50 INT277610 Binding of Runx2 and Hdac4 1 0.32 0.78 0
51 INT272524 DICER1 Negative_regulation of Dmpk 1 0.04 0.07 0
52 INT196022 Bmp7 Regulation of Bmp4 1 0.06 0.06 0
53 INT352150 Ift88 Negative_regulation of Bcl2 1 0.00 0.19 0
54 INT321594 Bmp2 Regulation of Gene_expression of Lxn 1 0.42 1.71 0
55 INT352149 Ift88 Negative_regulation of Bcl2l1 1 0.00 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of odontogenesis of dentin-containing tooth. They are ordered first by their pain relevance and then by number of times they were reported in regulation of odontogenesis of dentin-containing tooth. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
2 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
3 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
4 INT190280 Gene_expression of DICER1 12 0.65 9.54 2.67
5 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55
6 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
7 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
8 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
9 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
10 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
11 INT330526 Positive_regulation of Gene_expression of DICER1 5 0.30 3.34 1.18
12 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
13 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
14 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
15 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
16 INT43484 Binding of Runx2 7 0.37 3.22 0.95
17 INT114664 Binding of BMP2 12 0.37 6.54 0.91
18 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
19 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
20 INT142123 Positive_regulation of Gene_expression of Runx2 17 0.64 4.81 0.65
21 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
22 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
23 INT85808 Localization of BMP2 7 0.77 1.94 0.51
24 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
25 INT145301 Regulation of Gene_expression of Bmp2 1 0.32 1.16 0.48
26 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
27 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
28 INT120086 Gene_expression of Bmp2 5 0.27 2.34 0.43
29 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
30 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
31 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
32 INT272502 Transcription of DICER1 3 0.08 2.14 0.39
33 INT343811 Positive_regulation of Transcription of DICER1 1 0.06 2.06 0.39
34 INT84945 Transcription of BMP2 5 0.61 1.8 0.36
35 INT196026 Positive_regulation of Gene_expression of Bmp2 14 0.69 3.19 0.35
36 INT343810 Binding of DICER1 1 0.05 1.88 0.35
37 INT330525 Positive_regulation of DICER1 2 0.17 1.34 0.34
38 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34
39 INT145305 Positive_regulation of Bmp2 12 0.69 8.65 0.24
40 INT250836 Binding of Fgf8 3 0.35 0.66 0.24
41 INT109699 Regulation of BMP2 5 0.43 2.21 0.23
42 INT350691 Localization of DICER1 1 0.08 1.18 0.23
43 INT142117 Regulation of Runx2 6 0.61 2.75 0.22
44 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
45 INT250833 Localization of Fgf8 1 0.74 0.46 0.21
46 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21
47 INT171614 Positive_regulation of Runx2 13 0.63 3.04 0.19
48 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
49 INT171605 Negative_regulation of Runx2 4 0.46 2.14 0.17
50 INT148064 Localization of Bmp2 2 0.29 0.14 0.17
51 INT106010 Positive_regulation of Bmp2 2 0.26 0.91 0.15
52 INT250835 Positive_regulation of Fgf8 1 0.50 0.42 0.14
53 INT350685 Negative_regulation of Gene_expression of DICER1 1 0.05 0.15 0.14
54 INT350676 Regulation of Gene_expression of DICER1 1 0.07 0.16 0.14
55 INT254992 Negative_regulation of Gene_expression of BMP2 3 0.34 0.56 0.11
56 INT238044 Positive_regulation of Transcription of BMP2 2 0.43 0.83 0.11
57 INT326976 Regulation of Localization of BMP2 1 0.59 0.08 0.1
58 INT196035 Localization of Bmp2 3 0.63 0.23 0.09
59 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
60 INT278036 Negative_regulation of BMP2 2 0.34 0.64 0.09
61 INT114663 Regulation of Binding of BMP2 1 0.38 0.19 0.09
62 INT211942 Transcription of Runx2 3 0.69 2.46 0.08
63 INT163072 Regulation of Binding of Bmp2 1 0.30 0.52 0.08
64 INT210243 Negative_regulation of Bmp4 1 0.55 0.55 0.07
65 INT272508 Regulation of DICER1 4 0.11 1.21 0.05
66 INT196025 Negative_regulation of Bmp2 2 0.34 0.14 0.05
67 INT352129 Negative_regulation of Ift88 1 0.00 0.72 0.05
68 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04
69 INT229753 Positive_regulation of Gene_expression of Bmp2 2 0.11 1.22 0.04
70 INT210238 Positive_regulation of Negative_regulation of Bmp4 1 0.47 0 0.04
71 INT287236 Positive_regulation of Positive_regulation of BMP2 1 0.29 0.08 0.04
72 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04
73 INT196034 Positive_regulation of Gene_expression of Bmp4 4 0.45 0.63 0
74 INT260779 Negative_regulation of Bmp4 4 0.23 0.94 0
75 INT189593 Regulation of Gene_expression of BMP2 2 0.33 0.8 0
76 INT196027 Binding of Bmp4 2 0.13 0.97 0
77 INT142119 Regulation of Bmp4 2 0.58 0.29 0
78 INT145300 Positive_regulation of Positive_regulation of Bmp2 2 0.34 1.03 0
79 INT190271 Negative_regulation of DICER1 2 0.04 0.24 0
80 INT142118 Regulation of Gene_expression of Runx2 2 0.61 2.92 0
81 INT196031 Binding of Bmp2 1 0.16 0 0
82 INT211944 Regulation of Transcription of Runx2 1 0.34 0.32 0
83 INT278735 Negative_regulation of Gene_expression of Bmp2 1 0.43 0.06 0
84 INT286555 Binding of Ift88 1 0.30 0.08 0
85 INT339667 Localization of Bmp4 1 0.38 0.27 0
86 INT278737 Positive_regulation of Transcription of Bmp2 1 0.47 1.4 0
87 INT120087 Negative_regulation of Gene_expression of Bmp2 1 0.11 0.14 0
88 INT286544 Localization of Ift88 1 0.52 1.26 0
89 INT250830 Regulation of Protein_catabolism of Fgf8 1 0.45 0.08 0
90 INT311651 Positive_regulation of Fgf8 1 0.46 0.26 0
91 INT265814 Localization of Runx2 1 0.75 0.84 0
92 INT352844 Protein_catabolism of DICER1 1 0.12 0 0
93 INT250846 Positive_regulation of Protein_catabolism of Fgf8 1 0.50 0.07 0
94 INT278040 Negative_regulation of Localization of BMP2 1 0.32 0.32 0
95 INT277589 Regulation of Negative_regulation of Runx2 1 0.36 0.78 0
96 INT265813 Regulation of Binding of Runx2 1 0.27 0.19 0
97 INT171613 Positive_regulation of Positive_regulation of Runx2 1 0.01 0 0
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