GO:0042491

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Name auditory receptor cell differentiation
Categary Process
Go Slim No
Go Link GO:0042491
Unique Molecular Interactions 117
Total Molecular Interactions 200
Total Single Events 884
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for auditory receptor cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for auditory receptor cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
2 INT320021 Prkaca Regulation of Positive_regulation of Kcnma1 1 0.00 0.54 1
3 INT128602 Binding of Kcnma1 and Gtf2ird2 1 0.00 0 0.97
4 INT112642 Positive_regulation of Kcnma1 Positive_regulation of Nav1 1 0.02 0 0.89
5 INT98770 Binding of Dll1 and Gt(pU21)50Imeg 1 0.05 0 0.74
6 INT75399 Regulation of Binding of Dll1 and Oprd1 1 0.08 0 0.74
7 INT98771 Binding of Dll1 and Oprm1 1 0.29 0 0.74
8 INT75398 Binding of Dll1 and Oprd1 1 0.11 0 0.74
9 INT261517 Binding of HTR2A and USH1C 1 0.01 0 0.66
10 INT148381 UFM1 Positive_regulation of JAG1 1 0.00 1.13 0.63
11 INT223928 Cux1 Regulation of Gene_expression of Maoa 1 0.24 0.15 0.57
12 INT223924 Cux1 Regulation of Gene_expression of Serpina1 1 0.04 0.15 0.57
13 INT223934 HSPG2 Negative_regulation of Gene_expression of Cux1 1 0.03 0 0.53
14 INT223936 HSPG2 Positive_regulation of Gene_expression of Cux1 1 0.03 0 0.46
15 INT223935 HSPG2 Positive_regulation of Cux1 1 0.03 0 0.45
16 INT296448 Ush1c Regulation of Binding of Gria2 1 0.06 0.29 0.28
17 INT223927 Maoa Regulation of Positive_regulation of Cux1 1 0.24 0.1 0.27
18 INT165478 Prok2 Positive_regulation of Positive_regulation of Kcnma1 1 0.02 0 0.25
19 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
20 INT183444 POSTN Positive_regulation of CUX1 1 0.01 0 0.21
21 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
22 INT216487 Ca2 Negative_regulation of Kcnma1 1 0.00 0.1 0.17
23 INT298302 Binding of BDNF and CUX1 1 0.03 1.87 0.14
24 INT261519 Binding of HTR4 and USH1C 1 0.00 0 0.13
25 INT208983 Binding of Ca2 and Kcnma1 2 0.01 0.28 0.1
26 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
27 INT351422 Mfng Negative_regulation of Jag1 1 0.06 1.29 0.07
28 INT295130 Igf1 Regulation of Grxcr1 1 0.02 0.64 0.06
29 INT295122 Bmp2 Regulation of Grxcr1 1 0.02 0.66 0.06
30 INT216570 Gene_expression of cx Positive_regulation of Kcnma1 1 0.00 0.25 0.06
31 INT261556 Binding of USH1C and Olr1746 1 0.01 0 0.06
32 INT216545 Gene_expression of Cftr Negative_regulation of Kcnma1 1 0.00 0.59 0.06
33 INT147426 Mcoln3 Negative_regulation of Zfp419 1 0.01 0.1 0.05
34 INT303393 Binding of Jag1 and Tceb2 1 0.03 0.29 0.04
35 INT288595 Binding of CYTIP and Kcnma1 1 0.00 0 0.04
36 INT323286 CYP4A11 Positive_regulation of Kcnma1 1 0.01 0.45 0.04
37 INT332483 Binding of JAG1 and SGPP2 1 0.21 0.23 0.04
38 INT303389 Binding of Jag1 and Cul5 1 0.20 0.29 0.04
39 INT249891 Binding of Atoh1 and Olig2 1 0.08 0.14 0.03
40 INT295121 Proc Regulation of Grxcr1 1 0.00 1.26 0.03
41 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
42 INT303397 Binding of Jag1 and Gopc 1 0.13 0 0
43 INT100747 Kcnma1 Positive_regulation of sar 1 0.03 0 0
44 INT288584 Cav1 Regulation of Gene_expression of Kcnma1 1 0.14 0 0
45 INT288594 Regulation of Binding of CAV1 and Kcnma1 1 0.01 0 0
46 INT264735 Binding of Hes1 and Mir199b 1 0.08 0.93 0
47 INT303398 Jag1 Positive_regulation of Protein_catabolism of Myh3 1 0.52 0 0
48 INT264738 Mir199b Regulation of Gene_expression of Hes1 1 0.08 0.89 0
49 INT303405 Binding of NPAT and Jag1 1 0.39 0 0
50 INT227218 Binding of JAG1 and CD8A 1 0.05 0.5 0
51 INT350712 Binding of Gfi1 and MIR21 1 0.02 0.23 0
52 INT197313 Atoh1 Regulation of Neurod1 1 0.01 0.13 0
53 INT273886 Binding of Dll1 and Trip12 1 0.34 0.1 0
54 INT264736 Hes1 Regulation of Notch2 1 0.20 0.13 0
55 INT321772 Binding of Myo7a and Twf2 1 0.00 0 0
56 INT288587 Cav1 Regulation of Binding of Kcnma1 1 0.14 0 0
57 INT303404 Binding of TCAP and Jag1 1 0.39 0 0
58 INT288597 Binding of CAV1 and Kcnma1 1 0.01 0.17 0
59 INT197316 Hes1 Regulation of Atoh1 1 0.01 0.14 0
60 INT288596 Positive_regulation of Binding of CAV1 and Kcnma1 1 0.01 0.1 0
61 INT288593 Cav1 Positive_regulation of Binding of Kcnma1 1 0.15 0 0
62 INT290104 Myo7a Regulation of RPE 1 0.03 0.75 0
63 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
64 INT264731 Gene_expression of Hes1 Negative_regulation of Positive_regulation of Musd1 1 0.00 0.18 0
65 INT303399 Binding of Jag1 and Myh3 1 0.50 0.85 0
66 INT295124 Binding of Pou1f1 and Grxcr1 1 0.04 0.28 0
67 INT288591 Cav1 Positive_regulation of Kcnma1 1 0.15 0 0
68 INT197315 Hes5 Regulation of Atoh1 1 0.00 0.14 0
69 INT180470 Cdh23 Positive_regulation of Lpl 1 0.06 1.23 0
70 INT303391 Binding of Jag1 and Tceb1 1 0.44 0 0
71 INT197306 Atoh1 Regulation of Neurod6 1 0.00 0.13 0
72 INT197314 Hes5 Regulation of Ascl1 1 0.00 0.14 0
73 INT264729 Mir199b Regulation of Hes1 1 0.05 0.25 0
74 INT303386 Binding of Jag1 and Laptm5 1 0.02 0 0
75 INT255019 Myo7a Positive_regulation of F10 1 0.00 0.06 0
76 INT303390 Binding of Jag1 and Myo1f 1 0.07 0 0
77 INT288586 Cav1 Positive_regulation of Regulation of Kcnma1 1 0.21 0 0
78 INT183721 HPN Positive_regulation of MYO7A 1 0.02 1.55 0
79 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
80 INT303400 Jag1 Positive_regulation of Protein_catabolism of Gopc 1 0.25 0 0
81 INT266834 Pth Negative_regulation of Positive_regulation of Grxcr1 1 0.04 0.51 0
82 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
83 INT288583 Negative_regulation of Binding of Cav1 and Kcnma1 1 0.13 0 0
84 INT264734 Mir199b Negative_regulation of Negative_regulation of Hes1 1 0.07 0.1 0
85 INT288589 Cav1 Regulation of Kcnma1 1 0.19 0.05 0
86 INT264739 Mir199b Negative_regulation of Gene_expression of Hes1 1 0.07 0.82 0
87 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
88 INT303395 Positive_regulation of Binding of Jag1 and Myo1f 1 0.07 0 0
89 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0
90 INT273887 Binding of Jag1 and Notch2 1 0.02 1.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for auditory receptor cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in auditory receptor cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56
2 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19
3 INT50056 Positive_regulation of Dll1 13 0.67 3.16 13.7
4 INT35097 Gene_expression of Cux1 6 0.58 3.86 12.83
5 INT7458 Negative_regulation of Kcnma1 30 0.43 6.61 10.4
6 INT56019 Gene_expression of Dll1 11 0.78 3.38 8.71
7 INT43063 Positive_regulation of Cux1 3 0.49 1.57 7.13
8 INT58607 Negative_regulation of Dll1 9 0.43 1.89 7.06
9 INT70287 Positive_regulation of Gene_expression of Dll1 6 0.70 3.58 6.55
10 INT13051 Regulation of Kcnma1 12 0.12 2.09 5.06
11 INT57724 Regulation of Cux1 10 0.39 1.81 3.92
12 INT62678 Negative_regulation of JAG1 8 0.41 6.95 3.5
13 INT19903 Negative_regulation of Cux1 7 0.57 2.8 3.33
14 INT49190 Regulation of Dll1 3 0.44 0.26 3.24
15 INT55148 Binding of Dll1 5 0.48 0.66 2.97
16 INT66891 Negative_regulation of Positive_regulation of Dll1 1 0.41 0 2.72
17 INT91471 Positive_regulation of Gene_expression of Kcnma1 4 0.22 2.88 2.56
18 INT223921 Positive_regulation of Gene_expression of Cux1 1 0.49 0.83 2.36
19 INT64075 Positive_regulation of Positive_regulation of Kcnma1 2 0.02 0.55 1.96
20 INT303352 Gene_expression of Jag1 19 0.73 7.68 1.89
21 INT108978 Positive_regulation of CUX1 16 0.57 5.93 1.73
22 INT117033 Gene_expression of JAG1 13 0.65 11.46 1.52
23 INT303362 Regulation of Jag1 2 0.22 2.91 1.22
24 INT133371 Negative_regulation of Binding of Dll1 1 0.41 0.5 1.22
25 INT19904 Localization of Cux1 2 0.65 0.41 1.1
26 INT72255 Binding of Kcnma1 4 0.02 0.2 0.99
27 INT92428 Regulation of Myo7a 2 0.44 1.23 0.91
28 INT147423 Gene_expression of Mcoln3 5 0.78 3.25 0.89
29 INT223912 Negative_regulation of Gene_expression of Cux1 1 0.30 0.15 0.87
30 INT7457 Localization of Kcnma1 3 0.60 2.75 0.85
31 INT160227 Localization of Mcoln3 1 0.24 1.19 0.85
32 INT139928 Negative_regulation of Kcnma1 6 0.37 1.19 0.84
33 INT303347 Positive_regulation of Gene_expression of Jag1 6 0.65 4.06 0.77
34 INT160228 Positive_regulation of Mcoln3 1 0.22 1.12 0.76
35 INT69771 Positive_regulation of Kcnma1 6 0.52 0.31 0.74
36 INT139089 Negative_regulation of Gene_expression of Dll1 2 0.43 0 0.69
37 INT223908 Positive_regulation of Positive_regulation of Cux1 1 0.40 0.07 0.67
38 INT215809 Gene_expression of Kcnma1 11 0.58 0.53 0.66
39 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
40 INT74781 Regulation of JAG1 6 0.39 2.75 0.63
41 INT148382 Positive_regulation of JAG1 5 0.23 3.88 0.63
42 INT288019 Regulation of Gene_expression of Kcnma1 3 0.00 0.7 0.63
43 INT251632 Positive_regulation of Cdh23 1 0.00 0.27 0.63
44 INT101705 Negative_regulation of Positive_regulation of Kcnma1 2 0.03 0 0.59
45 INT151401 Localization of JAG1 4 0.65 1.88 0.58
46 INT180459 Gene_expression of Cdh23 4 0.14 5.11 0.52
47 INT307752 Negative_regulation of Regulation of Kcnma1 1 0.01 0.18 0.52
48 INT88806 Transcription of CUX1 3 0.69 1.45 0.5
49 INT88804 Regulation of Transcription of CUX1 1 0.60 0.97 0.5
50 INT223915 Positive_regulation of Regulation of Cux1 1 0.35 0 0.49
51 INT320019 Regulation of Positive_regulation of Kcnma1 1 0.01 0.05 0.49
52 INT115578 Regulation of Gene_expression of Cux1 2 0.19 0.08 0.45
53 INT92050 Negative_regulation of CUX1 1 0.21 1.91 0.44
54 INT223914 Regulation of Positive_regulation of Cux1 1 0.32 0.1 0.41
55 INT151400 Binding of JAG1 14 0.37 7.96 0.39
56 INT129456 Positive_regulation of MYO7A 3 0.20 3.15 0.36
57 INT261555 Binding of USH1C 1 0.01 0 0.34
58 INT343142 Negative_regulation of Regulation of Atoh1 1 0.41 0 0.33
59 INT180456 Regulation of Cdh23 3 0.06 2.83 0.32
60 INT343144 Regulation of Atoh1 1 0.43 0 0.32
61 INT236166 Gene_expression of Atoh1 4 0.65 0.09 0.3
62 INT99793 Regulation of Negative_regulation of Kcnma1 1 0.01 0.1 0.3
63 INT223913 Positive_regulation of Localization of Cux1 1 0.38 0.41 0.29
64 INT288561 Regulation of Kcnma1 5 0.21 0.49 0.26
65 INT152216 Negative_regulation of Negative_regulation of Cux1 1 0.37 1.13 0.26
66 INT273867 Binding of Jag1 18 0.45 3.14 0.25
67 INT303374 Negative_regulation of Jag1 2 0.48 0.9 0.23
68 INT343143 Positive_regulation of Atoh1 1 0.42 0.09 0.23
69 INT152957 Gene_expression of CUX1 4 0.75 0.18 0.21
70 INT16306 Binding of Cdh23 2 0.15 1.76 0.2
71 INT39893 Regulation of CUX1 1 0.22 0 0.2
72 INT266832 Positive_regulation of Grxcr1 9 0.12 7.91 0.19
73 INT343141 Negative_regulation of Atoh1 1 0.41 0.1 0.19
74 INT264701 Negative_regulation of Gene_expression of Hes1 1 0.42 0.73 0.18
75 INT296438 Positive_regulation of Ush1c 1 0.11 0.21 0.18
76 INT266822 Negative_regulation of Grxcr1 10 0.10 8.12 0.17
77 INT152217 Positive_regulation of Negative_regulation of Cux1 1 0.40 0.82 0.16
78 INT168523 Localization of Cdh23 2 0.22 0.27 0.15
79 INT250329 Positive_regulation of Gene_expression of Mcoln3 1 0.06 0.36 0.15
80 INT167957 Gene_expression of Grxcr1 8 0.10 3.43 0.14
81 INT72251 Phosphorylation of Kcnma1 2 0.05 0.07 0.13
82 INT124527 Positive_regulation of Myo7a 1 0.00 0.15 0.1
83 INT168521 Localization of Myo7a 1 0.18 0.17 0.1
84 INT240662 Binding of CUX1 2 0.18 0.95 0.09
85 INT129457 Regulation of Localization of MYO7A 1 0.19 0.33 0.08
86 INT129455 Localization of MYO7A 1 0.32 0.33 0.08
87 INT298251 Gene_expression of Hes5 2 0.45 0.39 0.06
88 INT266821 Positive_regulation of Negative_regulation of Grxcr1 1 0.06 1.51 0.06
89 INT266820 Positive_regulation of Positive_regulation of Grxcr1 1 0.06 1.58 0.06
90 INT288560 Binding of Kcnma1 1 0.16 0.16 0.05
91 INT219231 Positive_regulation of Gene_expression of JAG1 1 0.40 1.18 0.05
92 INT183448 Positive_regulation of Gene_expression of CUX1 1 0.12 0 0.04
93 INT295107 Negative_regulation of Gene_expression of Grxcr1 1 0.04 0.49 0.04
94 INT288573 Regulation of Gene_expression of Kcnma1 1 0.21 0 0.04
95 INT264717 Negative_regulation of Hes1 7 0.42 0.77 0.03
96 INT264704 Regulation of Hes1 4 0.44 1.03 0.03
97 INT266823 Regulation of Grxcr1 3 0.06 1.4 0.03
98 INT261548 Gene_expression of USH1C 1 0.02 0 0.03
99 INT264702 Positive_regulation of Gene_expression of Hes1 1 0.68 1.39 0.03
100 INT266818 Localization of Grxcr1 7 0.12 3.9 0
101 INT303349 Positive_regulation of Jag1 5 0.57 1.23 0
102 INT264719 Regulation of Gene_expression of Hes1 2 0.28 0.12 0
103 INT266819 Regulation of Localization of Grxcr1 2 0.06 1.28 0
104 INT286388 Transcription of Jag1 2 0.65 0.64 0
105 INT288559 Regulation of Positive_regulation of Kcnma1 1 0.21 0 0
106 INT264708 Transcription of Hes1 1 0.67 0.83 0
107 INT288577 Regulation of Localization of Kcnma1 1 0.21 0 0
108 INT295285 Positive_regulation of Negative_regulation of Kcnma1 1 0.08 0 0
109 INT203359 Protein_catabolism of Cdh23 1 0.09 0.52 0
110 INT288568 Regulation of Regulation of Kcnma1 1 0.09 0 0
111 INT288567 Localization of Kcnma1 1 0.27 0 0
112 INT303366 Negative_regulation of Gene_expression of Jag1 1 0.55 0.48 0
113 INT200593 Negative_regulation of Negative_regulation of CUX1 1 0.16 0.08 0
114 INT264705 Binding of Hes1 1 0.35 0.07 0
115 INT291480 Negative_regulation of Mcoln3 1 0.01 0.92 0
116 INT295108 Positive_regulation of Gene_expression of Grxcr1 1 0.07 0.52 0
117 INT350626 Binding of Gfi1 1 0.14 0.23 0
118 INT295083 Positive_regulation of Localization of Grxcr1 1 0.05 0.49 0
119 INT253798 Protein_catabolism of Kcnma1 1 0.57 0 0
120 INT298236 Localization of Hes5 1 0.51 0.39 0
121 INT350623 Regulation of Gfi1 1 0.09 0.24 0
122 INT295094 Regulation of Gene_expression of Grxcr1 1 0.04 0.07 0
123 INT288566 Negative_regulation of Binding of Kcnma1 1 0.15 0 0
124 INT264706 Positive_regulation of Hes1 1 0.40 0.14 0
125 INT303370 Protein_catabolism of Jag1 1 0.62 0.05 0
126 INT257560 Regulation of Negative_regulation of JAG1 1 0.13 0.48 0
127 INT303356 Localization of Jag1 1 0.70 0.09 0
128 INT180455 Negative_regulation of Cdh23 1 0.09 0.62 0
129 INT303348 Positive_regulation of Transcription of Jag1 1 0.44 0.64 0
130 INT303353 Negative_regulation of Binding of Jag1 1 0.40 0 0
131 INT67802 Binding of MYO7A 1 0.05 0.07 0
132 INT202851 Positive_regulation of Negative_regulation of Kcnma1 1 0.01 0.38 0
133 INT286831 Positive_regulation of Positive_regulation of Kcnma1 1 0.38 0.08 0
134 INT303367 Negative_regulation of Positive_regulation of Jag1 1 0.35 0.28 0
135 INT264146 Gene_expression of MYO7A 1 0.05 1.36 0
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