GO:0042503

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Name tyrosine phosphorylation of Stat3 protein
Categary Process
Go Slim No
Go Link GO:0042503
Unique Molecular Interactions 77
Total Molecular Interactions 99
Total Single Events 356
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tyrosine phosphorylation of Stat3 protein. They are ordered first by their pain relevance and then by number of times they were reported for tyrosine phosphorylation of Stat3 protein. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
2 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
3 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
4 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
5 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
6 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
7 INT149597 Lif Regulation of Regulation of Gal 1 0.30 0.69 0.73
8 INT149596 Lif Negative_regulation of Negative_regulation of Gal 1 0.10 0.5 0.7
9 INT82267 Lif Regulation of Gene_expression of Gal 1 0.40 2.76 0.62
10 INT149595 Lif Negative_regulation of Negative_regulation of Trpv1 1 0.34 0.44 0.61
11 INT333967 Binding of Osm and Sgp158 1 0.00 0.92 0.56
12 INT98480 Lif Positive_regulation of Pnoc 1 0.18 0.2 0.49
13 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
14 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
15 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
16 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
17 INT98484 Lif Regulation of Gene_expression of Gal 1 0.04 0.16 0.47
18 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
19 INT98482 Lif Positive_regulation of Gene_expression of Pnoc 1 0.16 0.17 0.46
20 INT98481 Lif Regulation of Regulation of Oprl1 1 0.04 0.16 0.45
21 INT188194 OSM Regulation of IL6 1 0.16 1.12 0.43
22 INT188205 OSM Regulation of LIF 1 0.09 1.12 0.43
23 INT162043 F2 Positive_regulation of Gene_expression of OSM 1 0.44 1.13 0.41
24 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
25 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
26 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
27 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
28 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
29 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
30 INT354790 MMP3 Negative_regulation of Gene_expression of OSM 1 0.00 0.27 0.31
31 INT162042 F2 Regulation of OSM 1 0.17 1.17 0.31
32 INT162039 F2 Regulation of Gene_expression of OSM 1 0.29 0.94 0.29
33 INT188209 OSM Positive_regulation of MAPK1 1 0.35 0.47 0.27
34 INT188203 EGF Positive_regulation of Protein_catabolism of OSM 1 0.30 0.17 0.21
35 INT188201 OSM Positive_regulation of Phosphorylation of STAT3 1 0.40 0.24 0.21
36 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21
37 INT82268 Lif Regulation of Gene_expression of Iapp 1 0.06 0.9 0.2
38 INT222426 Lif Positive_regulation of Localization of Pomc 1 0.02 0.75 0.17
39 INT32211 POMC Positive_regulation of Gene_expression of Lif 1 0.01 0.61 0.15
40 INT188198 OSM Positive_regulation of STAT3 1 0.52 0.24 0.12
41 INT188358 Binding of Csf2 and Positive_regulation of Jak2 1 0.34 0.19 0.11
42 INT169340 Binding of UGT8 and Jak2 1 0.36 0.15 0.11
43 INT138028 Binding of Osm and Il31 1 0.25 0.08 0.1
44 INT202409 Binding of Osm and Map3k3 1 0.20 0.13 0.09
45 INT202392 Binding of Osm and Nexn 1 0.02 0.13 0.09
46 INT202406 Binding of Osm and Mapk14 1 0.21 0.13 0.09
47 INT202400 Binding of Akt1 and Osm 1 0.05 0.13 0.09
48 INT202407 Binding of Osm and Racgap1 1 0.04 0.13 0.09
49 INT322851 Binding of KRIT1 and OSM 1 0.04 1.42 0.09
50 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08
51 INT322846 Binding of OSM and PDCD10 1 0.10 1.06 0.08
52 INT299539 Lif Positive_regulation of Phosphorylation of Stat3 1 0.08 0 0.08
53 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08
54 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08
55 INT188210 EGF Positive_regulation of OSM 1 0.28 0 0.07
56 INT299548 Binding of TGFB1 and Lif 1 0.02 0 0.07
57 INT299535 Binding of Egf and Lif 1 0.07 0 0.07
58 INT242480 Ciapin1 Positive_regulation of Gene_expression of Jak2 1 0.27 1.05 0.07
59 INT200807 Jak2 Positive_regulation of Mvd 1 0.18 3.46 0.06
60 INT261388 Nsdhl Regulation of Lif 1 0.08 0.67 0.04
61 INT200821 Binding of Jak2 and Mvd 1 0.14 0.68 0.04
62 INT261377 Nsdhl Positive_regulation of Lif 1 0.08 0.6 0.03
63 INT200813 Jak2 Positive_regulation of Akt1 1 0.26 1.46 0.03
64 INT253578 Csnk2a2 Negative_regulation of Jak2 1 0.09 0 0.03
65 INT253573 Binding of Jak2 and Pik3r1 1 0.06 0 0.03
66 INT200816 Jak2 Positive_regulation of Binding of Mvd 1 0.19 1.51 0.03
67 INT200810 Jak2 Positive_regulation of Src 1 0.29 1.46 0.03
68 INT249597 Jak2 Positive_regulation of Phosphorylation of Stat1 1 0.20 0.13 0.03
69 INT253575 Binding of Jak2 and Pik3r2 1 0.00 0 0.03
70 INT200815 Binding of Epo and Jak2 1 0.36 0.98 0.03
71 INT200822 Akt1 Regulation of Jak2 1 0.25 1.48 0.03
72 INT340502 Agtr1a Negative_regulation of Phosphorylation of Jak2 1 0.12 2.32 0
73 INT253366 Il6 Positive_regulation of Phosphorylation of Jak2 1 0.31 0.2 0
74 INT322847 Regulation of Binding of OSM and PDCD10 1 0.06 0 0
75 INT200819 Epo Positive_regulation of Gene_expression of Jak2 1 0.49 0.91 0
76 INT322875 Binding of OSM and Lyz2 1 0.00 0 0
77 INT241535 Abl1 Regulation of Positive_regulation of Jak2 1 0.10 0.53 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for tyrosine phosphorylation of Stat3 protein. They are ordered first by their pain relevance and then by number of times they were reported in tyrosine phosphorylation of Stat3 protein. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
2 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
3 INT32208 Gene_expression of Lif 23 0.74 6.23 3.7
4 INT81695 Gene_expression of OSM 14 0.75 7.29 3.58
5 INT82265 Gene_expression of Lif 7 0.50 6.17 3.4
6 INT76240 Positive_regulation of Lif 6 0.69 6.04 3.13
7 INT116798 Gene_expression of Osm 8 0.77 4.74 3.01
8 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
9 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
10 INT138021 Positive_regulation of Gene_expression of Osm 2 0.43 3.04 2
11 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
12 INT44027 Positive_regulation of Lif 7 0.40 2.76 1.9
13 INT203135 Negative_regulation of Gene_expression of Osm 1 0.12 3.08 1.73
14 INT203129 Binding of Osm 1 0.10 2.78 1.72
15 INT253751 Localization of Lif 3 0.73 3.94 1.58
16 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
17 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
18 INT173589 Localization of OSM 4 0.58 1.65 1.07
19 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04
20 INT149594 Positive_regulation of Gene_expression of Lif 2 0.47 0.89 1
21 INT188232 Positive_regulation of OSM 7 0.41 1.57 0.94
22 INT162048 Regulation of OSM 4 0.43 3.3 0.94
23 INT169336 Binding of Jak2 2 0.42 1.31 0.93
24 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
25 INT102819 Regulation of Lif 8 0.53 2.05 0.87
26 INT184027 Phosphorylation of Jak2 6 0.82 2.58 0.87
27 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
28 INT98478 Negative_regulation of Lif 3 0.42 1.29 0.84
29 INT82262 Regulation of Lif 3 0.31 1.67 0.83
30 INT354449 Positive_regulation of Localization of Lif 1 0.33 1.24 0.83
31 INT237408 Positive_regulation of Positive_regulation of Jak2 1 0.28 1.56 0.79
32 INT323909 Positive_regulation of Gene_expression of OSM 2 0.29 0.67 0.61
33 INT184456 Positive_regulation of Osm 3 0.24 1.41 0.54
34 INT184062 Binding of Jak2 5 0.37 3.13 0.47
35 INT216834 Localization of Lif 2 0.34 0.23 0.46
36 INT299516 Phosphorylation of Lif 1 0.26 0.56 0.46
37 INT205890 Transcription of Jak2 1 0.41 0.22 0.43
38 INT32207 Regulation of Gene_expression of Lif 3 0.19 1.01 0.42
39 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41
40 INT107462 Localization of Jak2 2 0.60 0.78 0.4
41 INT229697 Negative_regulation of Phosphorylation of Jak2 1 0.15 0.54 0.39
42 INT200786 Positive_regulation of Gene_expression of Jak2 9 0.69 6.03 0.35
43 INT205910 Negative_regulation of Positive_regulation of Jak2 1 0.33 0.26 0.35
44 INT162046 Negative_regulation of OSM 2 0.41 1.12 0.31
45 INT299519 Binding of Lif 2 0.21 0.67 0.29
46 INT264094 Localization of Osm 1 0.07 0.72 0.28
47 INT184437 Regulation of Osm 2 0.19 0.61 0.27
48 INT188220 Phosphorylation of OSM 6 0.59 0.69 0.24
49 INT188236 Protein_catabolism of OSM 1 0.63 0.17 0.21
50 INT318610 Positive_regulation of Binding of Lif 1 0.28 0.67 0.19
51 INT328811 Negative_regulation of Localization of Jak2 1 0.34 0.13 0.17
52 INT200802 Regulation of Jak2 5 0.61 2.86 0.16
53 INT338147 Negative_regulation of Gene_expression of Lif 1 0.38 0.29 0.15
54 INT216451 Negative_regulation of Lif 1 0.36 0.77 0.15
55 INT278143 Positive_regulation of Negative_regulation of Jak2 1 0.16 0.54 0.11
56 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09
57 INT184018 Negative_regulation of Protein_catabolism of Jak2 1 0.36 1.76 0.08
58 INT184023 Protein_catabolism of Jak2 1 0.61 1.75 0.08
59 INT333440 Protein_catabolism of Lif 1 0.23 0.2 0.08
60 INT216454 Binding of Lif 2 0.27 0.85 0.07
61 INT188233 Negative_regulation of Phosphorylation of OSM 1 0.31 0 0.07
62 INT299524 Positive_regulation of Localization of Lif 1 0.21 0 0.06
63 INT333439 Positive_regulation of Gene_expression of Lif 1 0.18 0.18 0.04
64 INT260819 Binding of OSM 2 0.12 0.66 0.03
65 INT322856 Regulation of Binding of OSM 1 0.10 0 0
66 INT159329 Transcription of Lif 1 0.36 0.15 0
67 INT300189 Negative_regulation of Localization of Lif 1 0.41 0.47 0
68 INT202420 Transcription of Jak2 1 0.56 0.91 0
69 INT216151 Transcription of OSM 1 0.19 0 0
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