GO:0042508

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Name tyrosine phosphorylation of Stat1 protein
Categary Process
Go Slim No
Go Link GO:0042508
Unique Molecular Interactions 57
Total Molecular Interactions 76
Total Single Events 266
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tyrosine phosphorylation of Stat1 protein. They are ordered first by their pain relevance and then by number of times they were reported for tyrosine phosphorylation of Stat1 protein. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
2 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
3 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
4 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
5 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
6 INT333967 Binding of Osm and Sgp158 1 0.00 0.92 0.56
7 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
8 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
9 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
10 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
11 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
12 INT188194 OSM Regulation of IL6 1 0.16 1.12 0.43
13 INT188205 OSM Regulation of LIF 1 0.09 1.12 0.43
14 INT162043 F2 Positive_regulation of Gene_expression of OSM 1 0.44 1.13 0.41
15 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
16 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
17 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
18 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
19 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
20 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
21 INT354790 MMP3 Negative_regulation of Gene_expression of OSM 1 0.00 0.27 0.31
22 INT162042 F2 Regulation of OSM 1 0.17 1.17 0.31
23 INT162039 F2 Regulation of Gene_expression of OSM 1 0.29 0.94 0.29
24 INT188209 OSM Positive_regulation of MAPK1 1 0.35 0.47 0.27
25 INT188203 EGF Positive_regulation of Protein_catabolism of OSM 1 0.30 0.17 0.21
26 INT188201 OSM Positive_regulation of Phosphorylation of STAT3 1 0.40 0.24 0.21
27 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21
28 INT188198 OSM Positive_regulation of STAT3 1 0.52 0.24 0.12
29 INT188358 Binding of Csf2 and Positive_regulation of Jak2 1 0.34 0.19 0.11
30 INT169340 Binding of UGT8 and Jak2 1 0.36 0.15 0.11
31 INT138028 Binding of Osm and Il31 1 0.25 0.08 0.1
32 INT202409 Binding of Osm and Map3k3 1 0.20 0.13 0.09
33 INT202392 Binding of Osm and Nexn 1 0.02 0.13 0.09
34 INT202406 Binding of Osm and Mapk14 1 0.21 0.13 0.09
35 INT202400 Binding of Akt1 and Osm 1 0.05 0.13 0.09
36 INT202407 Binding of Osm and Racgap1 1 0.04 0.13 0.09
37 INT322851 Binding of KRIT1 and OSM 1 0.04 1.42 0.09
38 INT322846 Binding of OSM and PDCD10 1 0.10 1.06 0.08
39 INT188210 EGF Positive_regulation of OSM 1 0.28 0 0.07
40 INT242480 Ciapin1 Positive_regulation of Gene_expression of Jak2 1 0.27 1.05 0.07
41 INT200807 Jak2 Positive_regulation of Mvd 1 0.18 3.46 0.06
42 INT200821 Binding of Jak2 and Mvd 1 0.14 0.68 0.04
43 INT200813 Jak2 Positive_regulation of Akt1 1 0.26 1.46 0.03
44 INT253578 Csnk2a2 Negative_regulation of Jak2 1 0.09 0 0.03
45 INT253573 Binding of Jak2 and Pik3r1 1 0.06 0 0.03
46 INT200816 Jak2 Positive_regulation of Binding of Mvd 1 0.19 1.51 0.03
47 INT200810 Jak2 Positive_regulation of Src 1 0.29 1.46 0.03
48 INT249597 Jak2 Positive_regulation of Phosphorylation of Stat1 1 0.20 0.13 0.03
49 INT253575 Binding of Jak2 and Pik3r2 1 0.00 0 0.03
50 INT200815 Binding of Epo and Jak2 1 0.36 0.98 0.03
51 INT200822 Akt1 Regulation of Jak2 1 0.25 1.48 0.03
52 INT340502 Agtr1a Negative_regulation of Phosphorylation of Jak2 1 0.12 2.32 0
53 INT253366 Il6 Positive_regulation of Phosphorylation of Jak2 1 0.31 0.2 0
54 INT322847 Regulation of Binding of OSM and PDCD10 1 0.06 0 0
55 INT200819 Epo Positive_regulation of Gene_expression of Jak2 1 0.49 0.91 0
56 INT322875 Binding of OSM and Lyz2 1 0.00 0 0
57 INT241535 Abl1 Regulation of Positive_regulation of Jak2 1 0.10 0.53 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for tyrosine phosphorylation of Stat1 protein. They are ordered first by their pain relevance and then by number of times they were reported in tyrosine phosphorylation of Stat1 protein. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
2 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
3 INT81695 Gene_expression of OSM 14 0.75 7.29 3.58
4 INT116798 Gene_expression of Osm 8 0.77 4.74 3.01
5 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
6 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
7 INT138021 Positive_regulation of Gene_expression of Osm 2 0.43 3.04 2
8 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
9 INT203135 Negative_regulation of Gene_expression of Osm 1 0.12 3.08 1.73
10 INT203129 Binding of Osm 1 0.10 2.78 1.72
11 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
12 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
13 INT173589 Localization of OSM 4 0.58 1.65 1.07
14 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04
15 INT188232 Positive_regulation of OSM 7 0.41 1.57 0.94
16 INT162048 Regulation of OSM 4 0.43 3.3 0.94
17 INT169336 Binding of Jak2 2 0.42 1.31 0.93
18 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
19 INT184027 Phosphorylation of Jak2 6 0.82 2.58 0.87
20 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
21 INT237408 Positive_regulation of Positive_regulation of Jak2 1 0.28 1.56 0.79
22 INT323909 Positive_regulation of Gene_expression of OSM 2 0.29 0.67 0.61
23 INT184456 Positive_regulation of Osm 3 0.24 1.41 0.54
24 INT184062 Binding of Jak2 5 0.37 3.13 0.47
25 INT205890 Transcription of Jak2 1 0.41 0.22 0.43
26 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41
27 INT107462 Localization of Jak2 2 0.60 0.78 0.4
28 INT229697 Negative_regulation of Phosphorylation of Jak2 1 0.15 0.54 0.39
29 INT200786 Positive_regulation of Gene_expression of Jak2 9 0.69 6.03 0.35
30 INT205910 Negative_regulation of Positive_regulation of Jak2 1 0.33 0.26 0.35
31 INT162046 Negative_regulation of OSM 2 0.41 1.12 0.31
32 INT264094 Localization of Osm 1 0.07 0.72 0.28
33 INT184437 Regulation of Osm 2 0.19 0.61 0.27
34 INT188220 Phosphorylation of OSM 6 0.59 0.69 0.24
35 INT188236 Protein_catabolism of OSM 1 0.63 0.17 0.21
36 INT328811 Negative_regulation of Localization of Jak2 1 0.34 0.13 0.17
37 INT200802 Regulation of Jak2 5 0.61 2.86 0.16
38 INT278143 Positive_regulation of Negative_regulation of Jak2 1 0.16 0.54 0.11
39 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09
40 INT184018 Negative_regulation of Protein_catabolism of Jak2 1 0.36 1.76 0.08
41 INT184023 Protein_catabolism of Jak2 1 0.61 1.75 0.08
42 INT188233 Negative_regulation of Phosphorylation of OSM 1 0.31 0 0.07
43 INT260819 Binding of OSM 2 0.12 0.66 0.03
44 INT322856 Regulation of Binding of OSM 1 0.10 0 0
45 INT202420 Transcription of Jak2 1 0.56 0.91 0
46 INT216151 Transcription of OSM 1 0.19 0 0
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