GO:0042524

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Name negative regulation of tyrosine phosphorylation of Stat5 protein
Categary Process
Go Slim No
Go Link GO:0042524
Unique Molecular Interactions 117
Total Molecular Interactions 173
Total Single Events 1004
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of tyrosine phosphorylation of Stat5 protein. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of tyrosine phosphorylation of Stat5 protein. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
2 INT92743 Binding of NF2 and LMOD1 1 0.00 0.08 0.46
3 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
4 INT92744 Binding of ADRB2 and NF2 1 0.00 0.1 0.41
5 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
6 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
7 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
8 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
9 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22
10 INT220520 Ugt1a6b Positive_regulation of Gene_expression of Cav1 1 0.01 0.81 0.17
11 INT254497 GOPC Regulation of Transcription of HNF4A 1 0.02 0.72 0.16
12 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15
13 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14
14 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
15 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
16 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12
17 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11
18 INT220517 Negative_regulation of Ugt1a6b Positive_regulation of Cav1 1 0.01 0.35 0.1
19 INT302977 Binding of Cav1 and Smpd2 1 0.08 0.71 0.09
20 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
21 INT254496 Binding of HNF4A and GOPC 1 0.10 0.34 0.08
22 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
23 INT183853 Gene_expression of CAV1 Negative_regulation of Positive_regulation of MAPK1 1 0.28 0.25 0.05
24 INT225230 Ad Positive_regulation of Nf2 1 0.04 1.37 0.04
25 INT220512 Cav1 Regulation of Positive_regulation of Cdkn1b 1 0.06 0.85 0.03
26 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
27 INT351167 CAV1 Negative_regulation of Ppp2r1a 1 0.08 1.5 0
28 INT288584 Cav1 Regulation of Gene_expression of Kcnma1 1 0.14 0 0
29 INT287892 PRDX2 Positive_regulation of HNF4A 1 0.00 0.52 0
30 INT288594 Regulation of Binding of CAV1 and Kcnma1 1 0.01 0 0
31 INT288588 Binding of Cav1 and Neu3 1 0.01 0 0
32 INT183895 CAV1 Regulation of Positive_regulation of Racgap1 1 0.01 0.37 0
33 INT219416 CCNA2 Regulation of HNF4A 1 0.00 0.11 0
34 INT235596 HNF4A Regulation of Gene_expression of TPI1 1 0.00 0.25 0
35 INT351166 Gtf3a Positive_regulation of Gene_expression of CAV1 1 0.01 0.79 0
36 INT351156 VEGFA Positive_regulation of Gene_expression of CAV1 1 0.07 0.79 0
37 INT182952 KCNIP3 Positive_regulation of HNF4A 1 0.02 0.45 0
38 INT287882 Binding of CREBBP and HNF4A 1 0.01 0.85 0
39 INT280961 Binding of Cav1 and Cpox 1 0.04 0 0
40 INT182922 FRA8E Positive_regulation of HNF4A 1 0.00 0.2 0
41 INT288587 Cav1 Regulation of Binding of Kcnma1 1 0.14 0 0
42 INT288597 Binding of CAV1 and Kcnma1 1 0.01 0.17 0
43 INT236528 Binding of Cav1 and Flna 1 0.06 0.09 0
44 INT307214 Hnf4a Regulation of Ppara 1 0.18 0.35 0
45 INT182926 VDR Positive_regulation of HNF4A 1 0.02 0.09 0
46 INT288596 Positive_regulation of Binding of CAV1 and Kcnma1 1 0.01 0.1 0
47 INT326836 Binding of HNF4A and PLD2 1 0.03 0.35 0
48 INT288590 Binding of Cav1 and Abhd14a 1 0.00 0 0
49 INT183857 CAV1 Positive_regulation of RHOC 1 0.46 0.21 0
50 INT183861 Binding of CAV1 and CDC42EP5 1 0.03 3.21 0
51 INT288593 Cav1 Positive_regulation of Binding of Kcnma1 1 0.15 0 0
52 INT219410 CCNF Regulation of HNF4A 1 0.01 0.11 0
53 INT182938 Binding of HNF4A and KCNIP3 1 0.01 0.2 0
54 INT219426 CDK2 Regulation of HNF4A 1 0.01 0.11 0
55 INT183864 Gene_expression of CAV1 Negative_regulation of Positive_regulation of RHOC 1 0.39 0.95 0
56 INT351165 Binding of CAV1 and Nos3 1 0.09 1.46 0
57 INT219420 CCNE2 Regulation of HNF4A 1 0.00 0.11 0
58 INT173123 Binding of HNF4A and PPARA 1 0.10 0.19 0
59 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0
60 INT183860 Binding of RHOC and CAV1 1 0.34 0.4 0
61 INT183856 Negative_regulation of RHOC Positive_regulation of Gene_expression of CAV1 1 0.42 0.09 0
62 INT183868 CAV1 Positive_regulation of PAF1 1 0.54 0.41 0
63 INT183018 Dre Positive_regulation of HNF4A 1 0.00 0.09 0
64 INT288591 Cav1 Positive_regulation of Kcnma1 1 0.15 0 0
65 INT262498 Binding of Aqp1 and Cav1 1 0.03 0.56 0
66 INT298103 Binding of Cav1 and Ca2 1 0.03 0 0
67 INT351164 CAV1 Negative_regulation of Ppp1cc 1 0.11 1.5 0
68 INT182957 CDKN1A Negative_regulation of HNF4A 1 0.02 0.11 0
69 INT182927 Binding of HNF4A and HRES1 1 0.00 0 0
70 INT220518 Cav1 Negative_regulation of Akt1 1 0.04 1.02 0
71 INT351158 CAV1 Regulation of SRC 1 0.01 0.68 0
72 INT326902 Binding of HNF4A and Tcf4 1 0.02 0.35 0
73 INT288592 Binding of Cav1 and Olfr1012 1 0.01 0 0
74 INT183866 CAV1 Regulation of RHOC 1 0.25 0.2 0
75 INT183867 Binding of CAV1 and Positive_regulation of Positive_regulation of RHOC 1 0.46 0.1 0
76 INT298104 Ca2 Negative_regulation of Cav1 1 0.04 0.09 0
77 INT315035 Binding of NAE1 and Cav1 1 0.01 0.7 0
78 INT288586 Cav1 Positive_regulation of Regulation of Kcnma1 1 0.21 0 0
79 INT183852 CAV1 Regulation of Positive_regulation of RHOC 1 0.41 0.63 0
80 INT288558 Binding of CAV1 and KCNMA1 1 0.00 0 0
81 INT288583 Negative_regulation of Binding of Cav1 and Kcnma1 1 0.13 0 0
82 INT220526 Binding of Akt1 and Cav1 1 0.03 1.02 0
83 INT288589 Cav1 Regulation of Kcnma1 1 0.19 0.05 0
84 INT351159 CAV1 Positive_regulation of AKT1 1 0.11 0.87 0
85 INT183854 Regulation of CAV1 Positive_regulation of RHOC 1 0.41 0.26 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of tyrosine phosphorylation of Stat5 protein. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of tyrosine phosphorylation of Stat5 protein. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
2 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
3 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
4 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
5 INT60750 Gene_expression of HNF4A 12 0.65 8.29 2.68
6 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
7 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
8 INT4188 Binding of NF2 7 0.46 3.52 1.79
9 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
10 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
11 INT141862 Binding of Cav1 11 0.36 1.32 1.25
12 INT172630 Binding of HNF4A 16 0.05 7.78 1.22
13 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
14 INT172616 Regulation of HNF4A 9 0.06 4.25 1.02
15 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
16 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
17 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
18 INT225221 Negative_regulation of Nf2 1 0.57 18.06 0.83
19 INT102262 Localization of NF2 1 0.14 0.6 0.79
20 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78
21 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77
22 INT112088 Regulation of Cav1 2 0.44 0.51 0.73
23 INT153667 Localization of CAV1 15 0.76 11.92 0.68
24 INT202848 Gene_expression of Nf2 5 0.59 4.93 0.63
25 INT86700 Regulation of Cav1 7 0.54 0.92 0.61
26 INT131001 Regulation of CAV1 6 0.44 3.77 0.59
27 INT141863 Negative_regulation of Gene_expression of Cav1 4 0.49 1.77 0.58
28 INT86702 Localization of Cav1 8 0.69 0.76 0.47
29 INT153672 Negative_regulation of Negative_regulation of CAV1 1 0.25 0.2 0.46
30 INT275642 Negative_regulation of HNF4A 4 0.05 2.08 0.44
31 INT220504 Positive_regulation of Gene_expression of Cav1 11 0.39 6.26 0.43
32 INT166240 Regulation of Gene_expression of Cav1 3 0.51 1.03 0.43
33 INT220506 Binding of Cav1 13 0.45 5.46 0.38
34 INT135953 Negative_regulation of Positive_regulation of Cav1 2 0.37 1.09 0.37
35 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35
36 INT106253 Positive_regulation of HNF4A 14 0.29 3.88 0.34
37 INT141867 Positive_regulation of Transcription of Cav1 2 0.52 0.46 0.29
38 INT141868 Transcription of Cav1 2 0.54 1.48 0.29
39 INT141861 Negative_regulation of Binding of Cav1 1 0.44 0.4 0.29
40 INT183208 Transcription of HNF4A 7 0.11 3.15 0.28
41 INT225219 Positive_regulation of Gene_expression of Nf2 1 0.43 1.27 0.27
42 INT135956 Phosphorylation of Cav1 5 0.64 2.24 0.22
43 INT135954 Positive_regulation of Phosphorylation of Cav1 2 0.40 0.64 0.22
44 INT141860 Regulation of Localization of Cav1 1 0.20 0.2 0.22
45 INT275639 Positive_regulation of Binding of HNF4A 2 0.04 0.87 0.21
46 INT60751 Positive_regulation of Gene_expression of HNF4A 2 0.49 3.5 0.19
47 INT220497 Regulation of Gene_expression of Cav1 4 0.36 1.84 0.18
48 INT86697 Negative_regulation of Regulation of Cav1 1 0.41 0 0.18
49 INT131000 Positive_regulation of Positive_regulation of CAV1 1 0.49 0 0.17
50 INT164022 Regulation of Gene_expression of HNF4A 1 0.03 0.82 0.16
51 INT145253 Negative_regulation of Cav1 9 0.46 3.02 0.15
52 INT202855 Regulation of Nf2 2 0.05 0.79 0.15
53 INT129118 Negative_regulation of NF2 2 0.56 1.89 0.15
54 INT163278 Regulation of Gene_expression of CAV1 5 0.45 4.36 0.14
55 INT214975 Localization of Cav1 7 0.75 2.7 0.13
56 INT287917 Phosphorylation of HNF4A 1 0.08 0.07 0.13
57 INT225224 Positive_regulation of Nf2 1 0.59 3.4 0.12
58 INT225222 Negative_regulation of Negative_regulation of Nf2 1 0.41 1.55 0.11
59 INT126667 Localization of HNF4A 2 0.06 0.45 0.08
60 INT220491 Transcription of Cav1 2 0.54 1.1 0.07
61 INT220500 Positive_regulation of Transcription of Cav1 1 0.16 0.9 0.07
62 INT53489 Regulation of NF2 2 0.44 1.34 0.06
63 INT220502 Positive_regulation of Positive_regulation of Cav1 1 0.24 0.21 0.05
64 INT315009 Regulation of Phosphorylation of Cav1 1 0.36 0.2 0.05
65 INT287925 Regulation of Binding of HNF4A 1 0.06 1.1 0.05
66 INT300713 Regulation of Localization of Cav1 2 0.42 1.37 0.04
67 INT225217 Positive_regulation of Positive_regulation of Nf2 1 0.43 1.07 0.04
68 INT225218 Positive_regulation of Negative_regulation of Nf2 1 0.40 1.07 0.04
69 INT314252 Transcription of CAV1 1 0.50 0.07 0.04
70 INT225227 Gene_expression of NF2 4 0.65 4.49 0.03
71 INT183878 Negative_regulation of Positive_regulation of CAV1 1 0.41 0.16 0.03
72 INT183883 Binding of CAV1 8 0.46 3.89 0
73 INT283550 Negative_regulation of Binding of Cav1 2 0.33 0.11 0
74 INT298115 Regulation of Binding of Cav1 1 0.12 0 0
75 INT326868 Positive_regulation of Transcription of HNF4A 1 0.04 0.08 0
76 INT183890 Regulation of Negative_regulation of CAV1 1 0.43 0.38 0
77 INT288581 Negative_regulation of Binding of CAV1 1 0.03 0 0
78 INT315010 Negative_regulation of Transcription of Cav1 1 0.34 0.21 0
79 INT285587 Positive_regulation of Localization of Cav1 1 0.11 0.08 0
80 INT288580 Regulation of Binding of CAV1 1 0.03 0 0
81 INT289452 Positive_regulation of NF2 1 0.01 0.08 0
82 INT288574 Negative_regulation of Negative_regulation of Cav1 1 0.33 0.06 0
83 INT326878 Negative_regulation of Gene_expression of HNF4A 1 0.03 0.43 0
84 INT287915 Positive_regulation of Positive_regulation of HNF4A 1 0.06 0.37 0
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