GO:0042538

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Name hyperosmotic salinity response
Categary Process
Go Slim No
Go Link GO:0042538
Unique Molecular Interactions 391
Total Molecular Interactions 600
Total Single Events 8001
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hyperosmotic salinity response. They are ordered first by their pain relevance and then by number of times they were reported for hyperosmotic salinity response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140015 Avp Positive_regulation of Localization of Penk 3 0.63 3.48 6.63
2 INT38217 Penk Regulation of Localization of Avp 2 0.38 0.56 4.45
3 INT161109 Avp Positive_regulation of Chkb 1 0.12 0.18 4.19
4 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
5 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
6 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61
7 INT140014 Avp Negative_regulation of Chkb 1 0.04 1.58 2.86
8 INT7888 Oprl1 Regulation of Localization of Avp 4 0.49 0.25 2.63
9 INT314141 Binding of Tacr3 and SFTPA1 1 0.00 3.02 2.48
10 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
11 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13
12 INT138960 Dbi Positive_regulation of Avp 1 0.02 1.53 2
13 INT138958 Dbi Positive_regulation of Positive_regulation of Avp 1 0.02 1.53 2
14 INT45423 Avp Positive_regulation of Localization of Prl 4 0.67 1.37 1.98
15 INT40239 Penk Regulation of Avp 1 0.07 0 1.84
16 INT40238 Penk Regulation of Oxt 1 0.04 0 1.83
17 INT117269 Binding of Avp and Prl 1 0.25 0.47 1.8
18 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
19 INT140009 Avp Positive_regulation of Gene_expression of Penk 1 0.40 0.77 1.64
20 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62
21 INT94271 Pomc Regulation of Avp 1 0.20 0.67 1.57
22 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56
23 INT140013 Avp Positive_regulation of Gene_expression of Dbi 1 0.07 0.85 1.52
24 INT140016 Avp Positive_regulation of Gene_expression of Pdyn 1 0.21 0.85 1.52
25 INT140017 Avp Positive_regulation of Gene_expression of Pomc 1 0.38 0.85 1.52
26 INT140008 Avp Positive_regulation of Pomc 1 0.38 0.84 1.51
27 INT64628 Binding of Oxt and Gal 2 0.29 0.29 1.49
28 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
29 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
30 INT140012 Avp Negative_regulation of Dbi 1 0.06 0.8 1.44
31 INT5534 Binding of Oxt and Avp 7 0.04 0.6 1.43
32 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
33 INT140021 Avp Positive_regulation of Pag1 1 0.03 0.85 1.38
34 INT140018 Avp Positive_regulation of Gene_expression of Pag1 1 0.04 0.85 1.38
35 INT140020 Avp Positive_regulation of Localization of Pag1 1 0.03 0.85 1.38
36 INT26812 SST Regulation of Localization of OXT 1 0.40 0.57 1.37
37 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36
38 INT7887 Oprl1 Regulation of Localization of Oxt 2 0.16 0 1.23
39 INT140010 Avp Regulation of Gene_expression of Penk 1 0.25 0.58 1.19
40 INT75126 Pnoc Regulation of Localization of Avp 2 0.26 0.24 1.18
41 INT27621 Avp Positive_regulation of Protein_catabolism of Mbis1 1 0.00 0 1.18
42 INT140022 Avp Regulation of Localization of Pag1 1 0.01 0.57 1.17
43 INT43509 Avp Positive_regulation of Localization of POMC 2 0.13 1.26 1.16
44 INT164722 Avp Regulation of NT5C 1 0.06 0.88 1.15
45 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
46 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
47 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
48 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
49 INT30359 Pomc Regulation of Localization of Oxt 1 0.03 0 1.13
50 INT86263 Binding of Tacr3 and Tac2 1 0.16 0.52 1.13
51 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
52 INT73679 Nkx1-1 Positive_regulation of Tacr3 1 0.22 0.26 1.12
53 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
54 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07
55 INT38936 Binding of Avp and Crh 7 0.40 0.82 1.04
56 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02
57 INT63103 AVP Regulation of OXT 1 0.28 0.68 1.02
58 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1
59 INT209151 OXT Positive_regulation of PNLIP 1 0.08 0.73 0.99
60 INT85320 Binding of Avp and Vas1 1 0.00 0.87 0.98
61 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
62 INT43454 Pomc Regulation of Localization of Avp 2 0.24 0.89 0.94
63 INT51543 Positive_regulation of Binding of Oxt and Penk 1 0.56 0.05 0.94
64 INT51542 Negative_regulation of Binding of Avp and Penk 1 0.46 0.05 0.94
65 INT314142 Binding of TAC1 and Tacr3 1 0.06 0.73 0.94
66 INT51544 Binding of Oxt and Penk 1 0.54 0.05 0.94
67 INT51541 Positive_regulation of Binding of Avp and Penk 1 0.74 0.05 0.94
68 INT51545 Binding of Avp and Penk 1 0.51 0.05 0.94
69 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
70 INT64127 Igfbp2 Regulation of Localization of Avp 1 0.39 0.19 0.9
71 INT121467 Binding of Avp and Ptafr 1 0.11 0.98 0.88
72 INT26529 Prl Regulation of Avp 1 0.08 0.26 0.85
73 INT26528 Prl Regulation of Oxt 1 0.26 0.26 0.85
74 INT64627 Binding of Oxt and Crh 1 0.07 0.1 0.83
75 INT19299 ANG Regulation of AVP 1 0.25 0 0.82
76 INT73032 Cck Negative_regulation of Localization of Oxt 1 0.44 0 0.82
77 INT16436 Ubqln1 Regulation of Localization of Avp 1 0.01 0 0.81
78 INT16439 Atp6v0d2 Regulation of Localization of Avp 1 0.02 0 0.81
79 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
80 INT39673 Binding of Oxt and Esyt1 1 0.04 0 0.78
81 INT9527 Avp Positive_regulation of Localization of Pomc 7 0.58 0.29 0.77
82 INT147251 Binding of Avp and Gal 1 0.15 0.19 0.76
83 INT159688 Trpv4 Negative_regulation of Trpv3 1 0.31 0.41 0.76
84 INT159689 Trpv4 Negative_regulation of Trpv1 1 0.36 0.41 0.76
85 INT15344 Oprd1 Regulation of Localization of Tacr3 1 0.00 0 0.76
86 INT159687 Trpv4 Negative_regulation of Trpv2 1 0.32 0.41 0.76
87 INT49044 Tac2 Regulation of Gene_expression of Tacr3 1 0.17 0.32 0.76
88 INT12396 Binding of Avp and IGKV1-5 3 0.04 1.38 0.75
89 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75
90 INT45305 Pomc Positive_regulation of Localization of Avp 1 0.12 0 0.73
91 INT48034 Binding of LH and Oxt 2 0.12 0 0.71
92 INT16437 Ubqln1 Positive_regulation of Localization of Oxt 1 0.03 0 0.7
93 INT164713 Binding of Avp and Positive_regulation of Localization of Acot1 1 0.32 0.43 0.69
94 INT164715 Avp Positive_regulation of Localization of Acot1 1 0.28 0.43 0.69
95 INT48032 Binding of Avp and Pebp1 1 0.00 0 0.68
96 INT48031 Binding of Oxt and Pebp1 1 0.01 0 0.68
97 INT11611 Cck Positive_regulation of Localization of Avp 1 0.09 0 0.67
98 INT11612 Cck Positive_regulation of Avp 1 0.10 0 0.67
99 INT129313 HTR2A Positive_regulation of Oxt 1 0.41 0.22 0.67
100 INT164723 Binding of Avp and NT5C 1 0.07 0.45 0.65
101 INT164714 Binding of Avp and Acot1 1 0.26 0.45 0.64
102 INT48033 Binding of Avp and LH 1 0.08 0 0.64
103 INT25957 Gabrg1 Regulation of Localization of AVP 1 0.01 0 0.62
104 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
105 INT32747 Avp Positive_regulation of Localization of Pomc 4 0.16 1.92 0.61
106 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61
107 INT37555 FDX1 Positive_regulation of Regulation of Avp 1 0.04 0 0.61
108 INT41220 Pomc Negative_regulation of Oxt 1 0.08 0 0.61
109 INT42269 POMC Negative_regulation of Localization of AVP 1 0.09 0 0.61
110 INT31808 Fam13a Negative_regulation of Oxt 1 0.07 0 0.6
111 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59
112 INT29847 INS Regulation of Localization of AVP 1 0.23 0.24 0.59
113 INT47498 Pomc Positive_regulation of Localization of Oxt 1 0.15 0 0.59
114 INT109803 Binding of Avp and Oprl1 1 0.07 0.1 0.59
115 INT64036 Binding of AVP and HTR1A 1 0.40 0.36 0.57
116 INT94506 Tnf Positive_regulation of Gene_expression of Avp 1 0.31 0.98 0.57
117 INT75128 Pnoc Regulation of Localization of Oxt 1 0.19 0 0.57
118 INT94507 Tnf Positive_regulation of Gene_expression of AVP 1 0.39 0.98 0.57
119 INT134488 Il1b Regulation of Oxt 1 0.30 0.08 0.54
120 INT255463 Binding of Avp and Avpr1a 1 0.06 0.67 0.54
121 INT209152 Regulation of OXT Positive_regulation of PNLIP 1 0.05 0.42 0.54
122 INT75129 Pnoc Negative_regulation of Avp 1 0.13 0 0.54
123 INT129869 SERPINA6 Regulation of AVP 1 0.25 2.33 0.54
124 INT75127 Pnoc Negative_regulation of Oxt 1 0.15 0 0.54
125 INT80833 Oxt Regulation of Ins1 1 0.04 0 0.53
126 INT80835 Oxt Positive_regulation of Regulation of Ins1 1 0.04 0 0.53
127 INT80836 Oxt Regulation of Sst 1 0.07 0 0.53
128 INT80834 Oxt Regulation of Cck 1 0.13 0 0.53
129 INT80832 Oxt Regulation of Gast 1 0.10 0 0.53
130 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52
131 INT51224 Gal Negative_regulation of Localization of Oxt 1 0.27 0.39 0.51
132 INT263228 Prkcg Regulation of Trpv4 1 0.07 0.36 0.5
133 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5
134 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
135 INT263235 Trpv4 Regulation of Trpv1 1 0.17 0.7 0.5
136 INT55553 Avp Regulation of Serpina6 1 0.02 0 0.49
137 INT161166 Binding of Aqp4 and Igh-6 1 0.03 2.58 0.49
138 INT47141 Creg2-ps1 Positive_regulation of Avp 1 0.01 0 0.48
139 INT47142 Negative_regulation of Creg2-ps1 Positive_regulation of Avp 1 0.01 0 0.48
140 INT66801 Oxt Regulation of Localization of Avp 1 0.08 0 0.48
141 INT27066 Crh Positive_regulation of Localization of Oxt 1 0.40 0 0.48
142 INT61848 Npff Regulation of Localization of Avp 1 0.26 0.3 0.48
143 INT59546 Avp Positive_regulation of Localization of Crh 1 0.05 0.08 0.47
144 INT16677 Binding of Avp and Oprd1 1 0.02 0.8 0.47
145 INT59548 Negative_regulation of Avp Positive_regulation of Crh 1 0.04 0.08 0.47
146 INT322131 Binding of Prkcg and Trpv4 1 0.04 0.75 0.46
147 INT27064 Kndc1 Positive_regulation of Localization of Oxt 1 0.00 0 0.46
148 INT19297 ANG Positive_regulation of AVP 1 0.28 0 0.46
149 INT175788 Il2 Positive_regulation of Localization of Avp 1 0.03 0.41 0.46
150 INT27065 Kndc1 Positive_regulation of Localization of Avp 1 0.00 0 0.46
151 INT43453 Pomc Negative_regulation of Localization of Avp 1 0.38 0.82 0.45
152 INT36459 Binding of Agt and Positive_regulation of Localization of Avp 1 0.38 0.19 0.43
153 INT69173 Avp Positive_regulation of Oxt 1 0.18 0 0.42
154 INT51026 Klra3 Positive_regulation of Gene_expression of Tacr3 1 0.05 0 0.42
155 INT79616 Htr1a Positive_regulation of Localization of Oxt 1 0.44 0 0.41
156 INT126979 Penk Negative_regulation of Localization of AVP 1 0.00 0 0.41
157 INT19298 ANG Regulation of OXT 1 0.07 0 0.41
158 INT36460 Binding of Agt and Avp 1 0.28 0.16 0.4
159 INT7634 RFC1 Negative_regulation of Localization of AVP 1 0.46 0 0.39
160 INT13077 Tac2 Positive_regulation of NKX2-1 1 0.00 0 0.39
161 INT40395 Ins1 Positive_regulation of Localization of Avp 1 0.16 0.09 0.38
162 INT79615 Htr1a Positive_regulation of Oxt 1 0.44 0 0.38
163 INT79614 Negative_regulation of Htr1a Positive_regulation of Oxt 1 0.38 0 0.38
164 INT84602 Binding of Adrb1 and Avp 1 0.00 0 0.36
165 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35
166 INT32698 Nppa Regulation of Oxt 1 0.57 0.35 0.35
167 INT32699 Nppa Regulation of Avp 1 0.28 0.35 0.35
168 INT84600 Binding of Avp and Aqp2 1 0.17 0 0.35
169 INT37552 Crh Regulation of Avp 1 0.22 0 0.34
170 INT37551 Positive_regulation of Crh Regulation of Avp 1 0.38 0 0.34
171 INT37554 Avp Regulation of FDX1 1 0.01 0 0.34
172 INT322133 Trpv4 Regulation of Ca2 1 0.04 0.16 0.33
173 INT106871 Grip2 Regulation of Tacr3 1 0.00 0 0.32
174 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32
175 INT31276 Oxt Negative_regulation of Cpe 1 0.01 0 0.31
176 INT66908 Il1b Positive_regulation of Localization of Avp 1 0.36 0.49 0.31
177 INT148342 Hsd17b6 Negative_regulation of Oxt 1 0.21 0.37 0.31
178 INT31275 Avp Negative_regulation of Cpe 1 0.00 0 0.31
179 INT12390 AVP Regulation of Localization of POMC 1 0.29 0.27 0.3
180 INT156261 Negative_regulation of Binding of Oxt and Ca2 1 0.16 0.12 0.3
181 INT15263 Gal Regulation of Localization of Avp 1 0.67 0 0.3
182 INT30706 Nppa Positive_regulation of Localization of AVP 1 0.78 0.45 0.3
183 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3
184 INT156262 Binding of Oxt and Ca2 1 0.14 0.12 0.3
185 INT89909 AVP Positive_regulation of Localization of POMC 1 0.44 0 0.29
186 INT89906 AVP Positive_regulation of Localization of GH1 1 0.14 0 0.29
187 INT89903 AVP Positive_regulation of Localization of PRL 1 0.40 0 0.29
188 INT51225 Gal Regulation of Localization of Oxt 1 0.32 0.35 0.29
189 INT45543 Ncapg2 Regulation of Localization of Avp 1 0.00 0 0.28
190 INT45542 Ncapg2 Regulation of Localization of Oxt 1 0.01 0 0.28
191 INT83410 Oxt Positive_regulation of Avp 1 0.20 0.35 0.28
192 INT322132 Binding of Mbp and Trpv4 1 0.11 0.39 0.27
193 INT45545 Agt Positive_regulation of Oxt 1 0.23 0 0.27
194 INT102923 Ptgds Regulation of Avp 1 0.02 0 0.27
195 INT72820 EDN3 Positive_regulation of Avp 1 0.31 0.64 0.27
196 INT63102 OXT Regulation of CALCRL 1 0.01 0.25 0.27
197 INT293118 Avp Regulation of Aqp2 1 0.04 0.7 0.27
198 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26
199 INT342164 Binding of Csf2 and Nkx2-1 1 0.01 0.52 0.26
200 INT74118 Adcyap1 Positive_regulation of Localization of Avp 1 0.33 0 0.26

Single Events

The table below shows the top 100 pain related interactions that have been reported for hyperosmotic salinity response. They are ordered first by their pain relevance and then by number of times they were reported in hyperosmotic salinity response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT477 Localization of Avp 813 0.81 131.58 300.4
2 INT3579 Localization of Oxt 555 0.81 43.35 292.44
3 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69
4 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7
5 INT4207 Regulation of Avp 267 0.62 63.72 115.33
6 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2
7 INT214 Localization of AVP 370 0.81 208.51 91.09
8 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7
9 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43
10 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58
11 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99
12 INT451 Regulation of Oxt 142 0.62 22.07 69.42
13 INT7468 Negative_regulation of Localization of Oxt 109 0.59 9.46 66.79
14 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47
15 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72
16 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71
17 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57
18 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41
19 INT685 Regulation of AVP 124 0.62 34.9 39.91
20 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23
21 INT109820 Gene_expression of Trpv4 121 0.78 39.69 33.11
22 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63
23 INT894 Binding of Avp 84 0.48 29.16 29.63
24 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91
25 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84
26 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09
27 INT7470 Positive_regulation of Gene_expression of Avp 37 0.70 19.55 19.96
28 INT5499 Transcription of Avp 52 0.72 7.98 19.87
29 INT5533 Binding of Oxt 43 0.48 8.69 18.35
30 INT119233 Positive_regulation of Trpv4 65 0.70 20.21 17.3
31 INT213 Negative_regulation of Localization of AVP 46 0.59 19.78 16.79
32 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64
33 INT7469 Positive_regulation of Gene_expression of Oxt 18 0.59 4.7 14.36
34 INT24956 Gene_expression of Tacr3 22 0.74 7.21 13.37
35 INT11141 Negative_regulation of Gene_expression of Avp 23 0.59 3.85 12.19
36 INT13743 Regulation of Gene_expression of Avp 30 0.62 6.9 11.66
37 INT15262 Negative_regulation of Positive_regulation of Avp 22 0.58 3.28 10.81
38 INT5939 Regulation of Gene_expression of Oxt 27 0.51 2.84 9.1
39 INT684 Binding of AVP 38 0.48 13.9 8.85
40 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62
41 INT26815 Regulation of OXT 15 0.46 5.38 8.31
42 INT124702 Positive_regulation of Trpv4 21 0.69 7.14 8.2
43 INT13739 Positive_regulation of Positive_regulation of Avp 18 0.70 4.78 8.2
44 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4
45 INT19302 Localization of OXT 31 0.79 3.39 6.92
46 INT66811 Positive_regulation of Transcription of Avp 11 0.70 2.1 6.46
47 INT7138 Regulation of Regulation of Avp 10 0.36 1.99 6.37
48 INT124881 Binding of Trpv4 35 0.47 7.71 6.24
49 INT38563 Negative_regulation of Gene_expression of Oxt 18 0.56 2.51 6.23
50 INT14490 Positive_regulation of Tacr3 14 0.53 1.83 5.77
51 INT21380 Regulation of Transcription of Avp 10 0.62 2.6 5.46
52 INT26280 Negative_regulation of Positive_regulation of Oxt 13 0.52 3.05 5.11
53 INT156296 Regulation of Trpv4 20 0.45 7.84 4.86
54 INT58097 Transcription of Oxt 18 0.69 1.62 4.6
55 INT13741 Positive_regulation of Positive_regulation of Oxt 13 0.56 0.44 4.29
56 INT143337 Binding of Aqp4 30 0.40 23.73 4.24
57 INT10849 Negative_regulation of OXT 14 0.48 2.51 4.19
58 INT51540 Positive_regulation of Negative_regulation of Oxt 3 0.47 1.19 4.1
59 INT19301 Regulation of Regulation of AVP 9 0.45 3.15 4.09
60 INT19300 Positive_regulation of OXT 34 0.43 4.43 4.07
61 INT8950 Gene_expression of Tacr3 12 0.76 0.97 4.07
62 INT109821 Negative_regulation of Trpv4 19 0.55 6.86 3.98
63 INT5299 Regulation of Tacr3 11 0.34 1.51 3.93
64 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79
65 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77
66 INT225965 Localization of Aqp4 26 0.81 18.85 3.75
67 INT15343 Localization of Tacr3 7 0.76 2.11 3.69
68 INT8952 Negative_regulation of Tacr3 7 0.42 0.36 3.62
69 INT130836 Transcription of Aqp4 6 0.72 5.93 3.52
70 INT18838 Positive_regulation of Regulation of Avp 3 0.47 0.48 3.32
71 INT30131 Positive_regulation of Negative_regulation of Avp 5 0.50 1.94 3.3
72 INT130835 Positive_regulation of Transcription of Aqp4 3 0.68 4.5 3.28
73 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22
74 INT8599 Binding of Tacr3 6 0.21 0.19 3.2
75 INT112175 Negative_regulation of Gene_expression of Trpv4 8 0.59 3.7 3.12
76 INT19553 Negative_regulation of Regulation of Avp 5 0.43 1.74 3.06
77 INT71398 Regulation of Tacr3 5 0.53 1.15 2.91
78 INT168744 Negative_regulation of Regulation of Trpv4 1 0.42 3.26 2.87
79 INT169402 Binding of Trpv4 8 0.47 5.13 2.78
80 INT10854 Gene_expression of OXT 13 0.66 3.88 2.74
81 INT10848 Negative_regulation of Gene_expression of AVP 13 0.59 6.76 2.71
82 INT115852 Transcription of Trpv4 9 0.71 2.23 2.65
83 INT109822 Negative_regulation of Gene_expression of Trpv4 8 0.55 1.98 2.53
84 INT115199 Localization of Trpv4 12 0.79 3.65 2.5
85 INT159809 Localization of Trpv4 6 0.78 3.67 2.46
86 INT46159 Positive_regulation of Positive_regulation of AVP 4 0.50 1.24 2.45
87 INT26813 Negative_regulation of Localization of OXT 4 0.57 0.72 2.45
88 INT156301 Regulation of Trpv4 11 0.60 2.81 2.35
89 INT156299 Phosphorylation of Trpv4 8 0.80 2.46 2.31
90 INT225966 Regulation of Gene_expression of Aqp4 18 0.62 20.39 2.3
91 INT86262 Negative_regulation of Tacr3 3 0.41 0.57 2.2
92 INT46160 Regulation of Positive_regulation of AVP 4 0.53 0.99 2.14
93 INT13075 Binding of NKX2-1 6 0.05 0.12 2.08
94 INT158442 Gene_expression of Nkx2-1 21 0.59 8.47 1.99
95 INT7375 Negative_regulation of Positive_regulation of AVP 6 0.43 0.37 1.97
96 INT24230 Localization of Tacr3 3 0.21 0 1.94
97 INT26281 Negative_regulation of Negative_regulation of Oxt 5 0.43 0.31 1.91
98 INT895 Negative_regulation of Binding of Avp 7 0.55 2.45 1.9
99 INT137670 Positive_regulation of Gene_expression of Trpv4 12 0.68 3.42 1.77
100 INT149153 Positive_regulation of Gene_expression of Trpv4 12 0.70 3.37 1.72
101 INT106091 Negative_regulation of Transcription of Avp 4 0.59 0.23 1.72
102 INT38648 Regulation of Positive_regulation of Oxt 2 0.37 0.5 1.61
103 INT110136 Positive_regulation of Transcription of Oxt 10 0.39 0.48 1.57
104 INT58598 Regulation of Gene_expression of Tacr3 1 0.37 0.98 1.54
105 INT164480 Negative_regulation of Gene_expression of Aqp4 14 0.58 10.84 1.52
106 INT149152 Negative_regulation of Trpv4 5 0.58 1.8 1.52
107 INT49042 Positive_regulation of Gene_expression of Tacr3 2 0.42 0.7 1.5
108 INT10852 Transcription of AVP 3 0.69 1.75 1.41
109 INT58597 Positive_regulation of Transcription of Tacr3 1 0.28 0.67 1.37
110 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
111 INT7139 Regulation of Regulation of Oxt 3 0.44 0.09 1.34
112 INT131984 Positive_regulation of Localization of Tacr3 1 0.01 0 1.28
113 INT41470 Protein_catabolism of Oxt 2 0.85 0.31 1.27
114 INT28645 Negative_regulation of Regulation of Oxt 3 0.23 0.35 1.24
115 INT33861 Negative_regulation of Binding of Oxt 6 0.42 0.6 1.14
116 INT58599 Transcription of Tacr3 3 0.43 1.02 1.12
117 INT78266 Localization of NKX2-1 2 0.73 0.16 1.12
118 INT261816 Positive_regulation of Localization of Trpv4 2 0.47 1.16 1.07
119 INT29825 Positive_regulation of Regulation of Oxt 1 0.49 0 1.05
120 INT10625 Regulation of Positive_regulation of Avp 4 0.44 1.06 1.04
121 INT15040 Gene_expression of NKX2-1 8 0.65 3.95 1.02
122 INT25718 Negative_regulation of Negative_regulation of Avp 4 0.58 0.5 1.02
123 INT8951 Negative_regulation of Gene_expression of Tacr3 2 0.42 0.14 1.01
124 INT8948 Regulation of Negative_regulation of Tacr3 1 0.15 0 1.01
125 INT101687 Positive_regulation of AVPR1B 6 0.40 2.95 0.95
126 INT19304 Positive_regulation of Localization of OXT 2 0.15 1 0.95
127 INT25539 Regulation of Gene_expression of AVP 9 0.45 2.74 0.89
128 INT63785 Positive_regulation of Tacr3 2 0.11 0.08 0.88
129 INT13074 Positive_regulation of NKX2-1 4 0.19 0.86 0.87
130 INT24957 Negative_regulation of Gene_expression of Tacr3 1 0.21 0.49 0.87
131 INT51704 Phosphorylation of AVP 2 0.79 0.33 0.86
132 INT51703 Positive_regulation of Phosphorylation of AVP 1 0.49 0.09 0.86
133 INT69749 Binding of Tacr3 3 0.06 2.2 0.81
134 INT156175 Positive_regulation of Positive_regulation of Trpv4 5 0.50 0.86 0.8
135 INT158547 Negative_regulation of Positive_regulation of Trpv4 2 0.57 0.47 0.77
136 INT149604 Regulation of Negative_regulation of AVP 2 0.44 0.49 0.77
137 INT86261 Regulation of Localization of Tacr3 1 0.16 0.4 0.77
138 INT235953 Regulation of Binding of Aqp4 4 0.45 4.4 0.76
139 INT28278 Positive_regulation of Binding of Oxt 2 0.43 0.75 0.76
140 INT235951 Positive_regulation of Positive_regulation of Aqp4 4 0.57 5.13 0.75
141 INT16676 Regulation of Negative_regulation of Avp 2 0.45 1.03 0.75
142 INT15039 Negative_regulation of NKX2-1 3 0.21 0 0.72
143 INT263225 Positive_regulation of Positive_regulation of Trpv4 3 0.46 0.75 0.7
144 INT156302 Positive_regulation of Phosphorylation of Trpv4 2 0.46 0.92 0.68
145 INT156303 Regulation of Regulation of Trpv4 2 0.27 0.26 0.63
146 INT118666 Negative_regulation of AVPR1B 7 0.43 2.88 0.59
147 INT158548 Regulation of Gene_expression of Trpv4 3 0.61 1.03 0.57
148 INT23228 Regulation of Localization of OXT 2 0.23 0.48 0.57
149 INT125188 Negative_regulation of Transcription of Trpv4 3 0.42 0.44 0.56
150 INT18644 Binding of OXT 6 0.31 1.22 0.55
151 INT91616 Regulation of Transcription of Oxt 1 0.43 0.06 0.53
152 INT6567 Positive_regulation of Regulation of AVP 2 0.67 0.93 0.51
153 INT209153 Negative_regulation of Positive_regulation of OXT 1 0.18 0.5 0.5
154 INT263224 Phosphorylation of Trpv4 2 0.76 0.73 0.49
155 INT137671 Negative_regulation of Positive_regulation of Trpv4 3 0.58 0.25 0.48
156 INT111869 Protein_catabolism of AVP 3 0.64 0.63 0.42
157 INT215052 Phosphorylation of Oxt 2 0.07 0.13 0.42
158 INT71921 Negative_regulation of Transcription of Oxt 1 0.38 0.07 0.42
159 INT125938 Negative_regulation of Binding of Tacr3 1 0.24 0.14 0.42
160 INT31738 Negative_regulation of Regulation of AVP 3 0.37 1.36 0.4
161 INT10850 Transcription of OXT 1 0.46 1.06 0.4
162 INT212307 Regulation of Gene_expression of Trpv4 8 0.44 2.85 0.39
163 INT106866 Positive_regulation of Binding of Tacr3 1 0.09 0 0.39
164 INT299223 Negative_regulation of Transcription of Aqp4 3 0.59 1.36 0.35
165 INT235950 Regulation of Regulation of Aqp4 1 0.37 1.96 0.34
166 INT41233 Regulation of Binding of Avp 1 0.24 0.33 0.32
167 INT236433 Regulation of Phosphorylation of Oxt 1 0.04 0 0.31
168 INT250095 Positive_regulation of Gene_expression of OXT 1 0.09 0.67 0.29
169 INT35611 Positive_regulation of Binding of AVP 1 0.43 0.19 0.28
170 INT247863 Positive_regulation of Negative_regulation of Aqp4 3 0.45 2.63 0.25
171 INT235946 Positive_regulation of Localization of Aqp4 1 0.41 1.32 0.25
172 INT91980 Positive_regulation of Positive_regulation of Tacr3 1 0.08 0.18 0.25
173 INT48343 Regulation of Regulation of Tacr3 1 0.04 0 0.25
174 INT247870 Negative_regulation of Localization of Aqp4 3 0.43 2 0.24
175 INT235947 Regulation of Localization of Aqp4 1 0.37 1.25 0.22
176 INT156172 Transcription of Trpv4 3 0.72 1.19 0.19
177 INT322153 Positive_regulation of Binding of Trpv4 1 0.49 0 0.18
178 INT159640 Negative_regulation of Regulation of Aqp4 1 0.42 0.78 0.18
179 INT215814 Negative_regulation of Gene_expression of Aqp1 2 0.31 0.25 0.17
180 INT214734 Positive_regulation of Positive_regulation of OXT 1 0.21 0 0.17
181 INT98625 Regulation of Aqp1 1 0.27 0.1 0.17
182 INT112424 Gene_expression of AVPR1B 6 0.65 1.35 0.16
183 INT200585 Negative_regulation of Binding of AVP 3 0.39 0.61 0.14
184 INT72708 Positive_regulation of Protein_catabolism of Oxt 1 0.48 0.32 0.14
185 INT24324 Regulation of NKX2-1 1 0.03 0.1 0.13
186 INT333015 Regulation of Binding of Trpv4 1 0.42 0.43 0.13
187 INT332570 Phosphorylation of Aqp4 1 0.59 0.9 0.13
188 INT215820 Negative_regulation of Aqp1 3 0.23 0.83 0.1
189 INT156173 Positive_regulation of Transcription of Trpv4 1 0.61 0.43 0.1
190 INT278552 Transcription of Tacr3 1 0.52 0 0.09
191 INT66457 Negative_regulation of Avpr1b 2 0.20 0.65 0.08
192 INT27838 Gene_expression of Avpr1b 1 0.33 0.48 0.08
193 INT262510 Regulation of Gene_expression of Aqp1 1 0.33 1.18 0.07
194 INT214733 Regulation of Gene_expression of OXT 2 0.21 0.15 0.06
195 INT32185 Positive_regulation of Avpr1b 2 0.22 0.61 0.06
196 INT177599 Binding of AVPR1B 2 0.04 0.49 0.04
197 INT250093 Regulation of Positive_regulation of OXT 1 0.08 0.13 0.04
198 INT222610 Localization of Avpr1b 1 0.73 0.33 0.03
199 INT215051 Regulation of Binding of Oxt 1 0.04 0 0.03
200 INT235949 Regulation of Positive_regulation of Aqp4 1 0.37 0 0.03
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