GO:0042542

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Name response to hydrogen peroxide
Categary Process
Go Slim No
Go Link GO:0042542
Unique Molecular Interactions 1382
Total Molecular Interactions 1818
Total Single Events 20305
Pain Genes Associated 84

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to hydrogen peroxide. They are ordered first by their pain relevance and then by number of times they were reported for response to hydrogen peroxide. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
2 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
3 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
4 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
5 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
6 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
7 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69
8 INT67905 Binding of Spn and Fosl1 1 0.24 2.1 2.54
9 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
10 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
11 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
12 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
13 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
14 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
15 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
16 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
17 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
18 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
19 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
20 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
21 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
22 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
23 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
24 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
25 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
26 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
27 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
28 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
29 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
30 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
31 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
32 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4
33 INT154685 Syt17 Positive_regulation of Trpa1 1 0.32 0.71 1.4
34 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
35 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
36 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3
37 INT158144 Binding of Gpx1 and Glyat 2 0.31 0 1.29
38 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
39 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
40 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
41 INT162165 WDTC1 Positive_regulation of PLD2 1 0.50 0 1.25
42 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
43 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
44 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
45 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
46 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
47 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
48 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
49 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16
50 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
51 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
52 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
53 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
54 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
55 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
56 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
57 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
58 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
59 INT167429 Negative_regulation of Mapk8 Negative_regulation of RYBP 1 0.01 1.11 1.09
60 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
61 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
62 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
63 INT87805 Pnoc Negative_regulation of Gene_expression of Fosl1 1 0.33 0 1.08
64 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
65 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
66 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
67 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
68 INT223875 Negative_regulation of Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.31 0 1.07
69 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
70 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03
71 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
72 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
73 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
74 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
75 INT134384 Trpa1 Negative_regulation of Gene_expression of Trpm8 1 0.47 1.21 1.02
76 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
77 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
78 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
79 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
80 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
81 INT166625 Acer3 Positive_regulation of Trpa1 1 0.01 1.91 1
82 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
83 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
84 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
85 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
86 INT65631 Ufm1 Positive_regulation of Kcna5 1 0.02 0 0.99
87 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
88 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
89 INT307100 Trpv1 Regulation of Binding of Trpa1 1 0.31 1.81 0.97
90 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
91 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
92 INT307103 Trpa1 Regulation of Binding of Trpv1 1 0.31 1.81 0.97
93 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
94 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
95 INT155985 Nfkb1 Negative_regulation of Gene_expression of Cyp11a1 1 0.10 0.53 0.95
96 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
97 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
98 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
99 INT149389 Olfr1241 Positive_regulation of Trpa1 1 0.02 0.31 0.94
100 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
101 INT139330 Binding of SGCG and Stat1 1 0.37 0.75 0.94
102 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94
103 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
104 INT89515 Pnoc Regulation of Gene_expression of Fosl1 1 0.09 0.98 0.93
105 INT221916 RPS3AP18 Negative_regulation of Positive_regulation of Trpa1 1 0.00 0.75 0.93
106 INT143323 Binding of HLA-B and HP 1 0.04 0.95 0.93
107 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
108 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
109 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
110 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 0.03 1.09 0.92
111 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
112 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.09 0.91
113 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
114 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9
115 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
116 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
117 INT75920 Slc8a1 Negative_regulation of Cpox 1 0.03 0.85 0.89
118 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
119 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
120 INT149391 Trpa1 Positive_regulation of Positive_regulation of Olfr1241 1 0.03 0.26 0.88
121 INT168019 Ldha Regulation of Gpt 1 0.01 0.15 0.88
122 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
123 INT168018 Positive_regulation of Ldha Regulation of Gpt 1 0.01 0.15 0.88
124 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
125 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
126 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
127 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 0.12 0.27 0.86
128 INT307045 Tmie Negative_regulation of Positive_regulation of Casp3 1 0.01 0.29 0.85
129 INT270218 P2rx3 Positive_regulation of Pla2g4a 1 0.34 0.63 0.85
130 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
131 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
132 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83
133 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
134 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
135 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81
136 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8
137 INT190182 JUN Positive_regulation of MMP12 1 0.34 0.08 0.8
138 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
139 INT131650 Cck Positive_regulation of Fosl1 1 0.17 0 0.8
140 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79
141 INT107739 Prkcg Negative_regulation of Positive_regulation of Pld2 1 0.46 0 0.79
142 INT150643 Binding of Bdkrb2 and Trpa1 1 0.36 0.55 0.78
143 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
144 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
145 INT152234 Mapk8 Positive_regulation of Localization of Nfkb1 1 0.33 0.26 0.78
146 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
147 INT166902 NPPB Positive_regulation of TRPA1 1 0.78 0.76 0.77
148 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77
149 INT124384 ADRBK1 Negative_regulation of MC1R 1 0.40 0.42 0.77
150 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
151 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
152 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 0.18 0.39 0.76
153 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
154 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76
155 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
156 INT90123 Jun Positive_regulation of Gene_expression of Fos 1 0.47 0.39 0.76
157 INT91655 SLC8A1 Negative_regulation of CASP1 1 0.02 0.43 0.75
158 INT307044 Tmie Regulation of Casp3 1 0.01 0 0.75
159 INT250959 Binding of HLA-B and SOD1 1 0.05 0.75 0.75
160 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74
161 INT98179 Aap Positive_regulation of Mapk8 1 0.01 0.75 0.74
162 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
163 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
164 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
165 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
166 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
167 INT190169 Regulation of JUN Positive_regulation of Localization of MMP12 1 0.30 0.07 0.74
168 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
169 INT114860 Negative_regulation of Insrr Positive_regulation of Casp3 1 0.02 0.71 0.73
170 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
171 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
172 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72
173 INT296097 Acsm3 Negative_regulation of SOD1 1 0.01 1.3 0.72
174 INT34823 Regulation of Binding of Ldha and Akr7a3 1 0.43 0.28 0.72
175 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
176 INT142225 Urb1 Positive_regulation of Trpa1 1 0.04 0.59 0.71
177 INT307754 Ik Negative_regulation of Trpa1 1 0.07 0.08 0.71
178 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
179 INT221938 Binding of TRPA1 and Tceb1 1 0.02 0 0.71
180 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71
181 INT82767 Binding of HP and MLRG 1 0.00 0 0.71
182 INT223873 Mapk8 Regulation of Positive_regulation of Ltp 1 0.24 0 0.71
183 INT34824 Binding of Ldha and Akr7a3 1 0.36 0.28 0.71
184 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
185 INT107741 Binding of OPRM1 and Pld2 1 0.01 0 0.69
186 INT66581 Binding of JUN and Rare2 1 0.00 0.07 0.69
187 INT263049 Positive_regulation of Binding of Mmp2 and Mmp9 1 0.35 0.83 0.69
188 INT140235 ADRBK1 Positive_regulation of Binding of MC1R 1 0.46 0.31 0.68
189 INT99743 Olr1742 Regulation of Gene_expression of Hmox1 1 0.00 0 0.68
190 INT134029 Olr696 Regulation of Ldha 1 0.00 0.15 0.68
191 INT140237 Gene_expression of ADRBK1 Positive_regulation of Gene_expression of MC1R 1 0.46 0.31 0.68
192 INT223869 Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.20 0 0.68
193 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
194 INT134286 PLD2 Regulation of Regulation of EDNRA 1 0.10 0 0.67
195 INT134287 PLD2 Regulation of Regulation of MRGPRX1 1 0.31 0 0.67
196 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
197 INT283049 Car2 Positive_regulation of Trpa1 1 0.20 1.33 0.67
198 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66
199 INT86519 Binding of Hmox1 and Hmox2 1 0.08 0.1 0.66
200 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to hydrogen peroxide. They are ordered first by their pain relevance and then by number of times they were reported in response to hydrogen peroxide. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
2 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
3 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
4 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65
5 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9
6 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
7 INT109431 Gene_expression of Trpa1 123 0.78 51.84 59.98
8 INT3920 Localization of Ldha 241 0.81 83.08 58.72
9 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
10 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
11 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
12 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
13 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14
14 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43
15 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
16 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
17 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
18 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
19 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
20 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
21 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17
22 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
23 INT47764 Binding of Jun 106 0.48 22.62 31.39
24 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
25 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
26 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
27 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
28 INT149387 Negative_regulation of Trpa1 55 0.59 21.91 28.31
29 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
30 INT127499 Positive_regulation of TRPA1 72 0.70 21.7 26.86
31 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79
32 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
33 INT5199 Gene_expression of Fosl1 44 0.78 8.66 24.8
34 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
35 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
36 INT127500 Gene_expression of TRPA1 79 0.78 24.58 23.3
37 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
38 INT4369 Gene_expression of Ldha 157 0.76 88.12 22.45
39 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
40 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25
41 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
42 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
43 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
44 INT1278 Negative_regulation of Ldha 93 0.59 37.66 19.36
45 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
46 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
47 INT187513 Positive_regulation of Pla2g4a 5 0.62 34.09 18.22
48 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64
49 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
50 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24
51 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15
52 INT195831 Phosphorylation of Pla2g4a 15 0.74 34.43 17.14
53 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07
54 INT134596 Regulation of Trpa1 32 0.62 18.78 17.02
55 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89
56 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86
57 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
58 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
59 INT48540 Gene_expression of Kcna5 37 0.77 14.04 16.07
60 INT4340 Positive_regulation of Localization of Ldha 46 0.70 14.52 15.66
61 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15
62 INT32802 Negative_regulation of Ada 21 0.57 4.03 14.87
63 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
64 INT17593 Regulation of Jun 37 0.60 5.5 14.35
65 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01
66 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88
67 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
68 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
69 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
70 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8
71 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52
72 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4
73 INT120432 Regulation of Trpa1 22 0.61 9.65 12.36
74 INT12191 Negative_regulation of Localization of Ldha 35 0.59 13.71 12.35
75 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
76 INT8548 Gene_expression of HP 86 0.77 47.62 11.94
77 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77
78 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65
79 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
80 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44
81 INT373 Regulation of Ldha 37 0.61 17.86 11.41
82 INT7903 Positive_regulation of Fosl1 21 0.70 3.53 11.36
83 INT270238 Localization of Pla2g4a 1 0.72 17.99 11.35
84 INT52233 Transcription of Jun 37 0.66 6.39 11.15
85 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
86 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03
87 INT192967 Gene_expression of Hp 14 0.43 8.06 11.01
88 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92
89 INT273123 Binding of Hp 1 0.25 3.56 10.9
90 INT65627 Negative_regulation of Kcna5 19 0.59 7.82 10.79
91 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76
92 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
93 INT2791 Regulation of Mb 53 0.61 23.03 10.73
94 INT54706 Regulation of Adrbk1 11 0.62 0.89 10.69
95 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
96 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
97 INT60198 Binding of JUN 54 0.48 11.56 10.27
98 INT2792 Gene_expression of Mb 91 0.76 41.56 10.25
99 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
100 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98
101 INT75919 Gene_expression of Slc8a1 23 0.63 16.44 9.84
102 INT145695 Regulation of Mapk8 26 0.62 14.67 9.83
103 INT134597 Binding of Trpa1 21 0.48 9.41 9.74
104 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51
105 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
106 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08
107 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
108 INT111998 Positive_regulation of Positive_regulation of Mapk8 23 0.69 9.33 8.97
109 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83
110 INT146346 Negative_regulation of Gene_expression of Trpa1 15 0.59 11.76 8.83
111 INT66213 Localization of RELA 63 0.78 14.71 8.77
112 INT146241 Positive_regulation of Gene_expression of Trpa1 23 0.69 8.07 8.74
113 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
114 INT104481 Regulation of Mapk8 21 0.50 13.87 8.41
115 INT4159 Gene_expression of Hp 33 0.72 12.49 8.39
116 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
117 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
118 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
119 INT45234 Binding of Ldha 20 0.37 9.8 8.18
120 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16
121 INT96912 Positive_regulation of Phosphorylation of Mapk8 29 0.69 18.33 8.14
122 INT82450 Negative_regulation of Hmox1 33 0.55 19.07 8.12
123 INT130502 Negative_regulation of Trpa1 17 0.59 5.75 8.06
124 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99
125 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
126 INT3401 Positive_regulation of Hp 22 0.69 16.33 7.97
127 INT4663 Positive_regulation of Ada 17 0.69 9.48 7.93
128 INT81345 Gene_expression of ADRBK1 21 0.70 2.89 7.9
129 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
130 INT98178 Localization of Casp3 32 0.65 21.01 7.77
131 INT14043 Binding of HP 52 0.30 26.56 7.76
132 INT39406 Positive_regulation of OLR1 45 0.70 37.8 7.72
133 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
134 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
135 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61
136 INT99071 Positive_regulation of Gene_expression of Mapk8 16 0.55 9.87 7.58
137 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
138 INT98856 Negative_regulation of Gene_expression of Adrbk1 5 0.56 0.43 7.29
139 INT134379 Binding of Trpa1 13 0.48 7.16 7.27
140 INT106757 Gene_expression of Dusp1 9 0.66 10.45 7.26
141 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25
142 INT65630 Regulation of Kcna5 11 0.62 6.61 7.22
143 INT111398 Localization of Mmp2 37 0.76 23.78 7.17
144 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
145 INT75497 Regulation of JUN 28 0.61 11.04 7.09
146 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
147 INT32709 Negative_regulation of Hbb 30 0.54 18.27 6.97
148 INT131745 Positive_regulation of Gene_expression of Trpa1 13 0.69 8.07 6.95
149 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91
150 INT47817 Positive_regulation of Positive_regulation of Jun 21 0.66 3.7 6.83
151 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
152 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
153 INT126484 Localization of Trpa1 15 0.80 4.08 6.64
154 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56
155 INT131744 Transcription of Trpa1 9 0.68 7.67 6.47
156 INT107737 Positive_regulation of Pld2 11 0.67 0.33 6.45
157 INT134290 Positive_regulation of PLD2 10 0.68 3.06 6.44
158 INT47765 Negative_regulation of Binding of Jun 21 0.43 5.05 6.38
159 INT48541 Positive_regulation of Kcna5 12 0.69 5.51 6.35
160 INT2442 Localization of Mb 38 0.80 24.74 6.33
161 INT57232 Binding of Casp3 22 0.36 9.42 6.2
162 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
163 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01
164 INT123551 Regulation of Mmp2 17 0.57 11.6 6
165 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98
166 INT169687 Regulation of Gene_expression of Trpa1 10 0.60 7.02 5.94
167 INT73649 Phosphorylation of Jun 28 0.80 11.01 5.87
168 INT63177 Regulation of HP 71 0.44 39.48 5.86
169 INT87470 Gene_expression of SDC1 27 0.78 24.86 5.81
170 INT82451 Negative_regulation of HMOX1 18 0.51 13.29 5.74
171 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
172 INT29674 Gene_expression of Ada 16 0.78 4.59 5.69
173 INT30206 Negative_regulation of ADA 17 0.59 10.03 5.63
174 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55
175 INT100222 Binding of Src 9 0.26 5.41 5.37
176 INT128922 Negative_regulation of Gene_expression of Mapk8 6 0.34 3.93 5.36
177 INT106756 Positive_regulation of Gene_expression of Dusp1 7 0.59 7.65 5.24
178 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
179 INT39900 Positive_regulation of Gene_expression of Ldha 36 0.50 20.35 5.22
180 INT147869 Positive_regulation of Gene_expression of TRPA1 5 0.70 5.33 5.21
181 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18
182 INT135291 Positive_regulation of Positive_regulation of Mapk8 24 0.64 19.37 5.16
183 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
184 INT36256 Regulation of Ada 9 0.62 4.99 5.07
185 INT5201 Negative_regulation of Gene_expression of Fosl1 8 0.54 1.63 5.06
186 INT53007 Regulation of Gene_expression of Fosl1 6 0.27 1.28 5.06
187 INT131717 Positive_regulation of Gene_expression of Mapk8 18 0.55 14.25 5.02
188 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
189 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
190 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
191 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87
192 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77
193 INT147870 Binding of TRPA1 11 0.48 3.12 4.77
194 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75
195 INT137332 Positive_regulation of Gene_expression of Sod1 41 0.70 19.8 4.69
196 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
197 INT29502 Localization of Mmp2 18 0.79 3.49 4.64
198 INT23045 Positive_regulation of Hbb 31 0.64 19.35 4.54
199 INT115805 Gene_expression of PLD2 7 0.76 12.49 4.51
200 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
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