GO:0042552

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Name myelination
Categary Process
Go Slim No
Go Link GO:0042552
Unique Molecular Interactions 557
Total Molecular Interactions 741
Total Single Events 5959
Pain Genes Associated 39

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for myelination. They are ordered first by their pain relevance and then by number of times they were reported for myelination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
2 INT211694 Binding of Cntnap1 and Nav1 1 0.04 0 3.14
3 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
4 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
5 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
6 INT105716 Vta1 Regulation of Nfasc 1 0.14 0 1.89
7 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
8 INT190981 Binding of Npy and Scn2a1 1 0.10 0 1.75
9 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
10 INT49083 Mbp Positive_regulation of Eae1 1 0.02 2.96 1.71
11 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
12 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54
13 INT96707 Ntf3 Positive_regulation of Localization of SST 1 0.01 0 1.3
14 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29
15 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
16 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
17 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
18 INT341479 Binding of SCN2A and SCN4A 1 0.37 1.29 0.98
19 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
20 INT137092 Ntf3 Negative_regulation of Gene_expression of Gal 1 0.47 1.01 0.9
21 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
22 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
23 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
24 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
25 INT152835 Prkcg Regulation of Phosphorylation of Nfasc 1 0.10 0.21 0.87
26 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
27 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
28 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
29 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
30 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
31 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78
32 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78
33 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
34 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
35 INT145646 Binding of Scn2a1 and Scn5a 1 0.36 0 0.76
36 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
37 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
38 INT170658 Binding of Ntf3 and Csf2 1 0.33 0.8 0.74
39 INT190986 Per1 Positive_regulation of Scn2a1 1 0.17 0 0.74
40 INT190979 Per2 Positive_regulation of Scn2a1 1 0.20 0 0.74
41 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
42 INT351351 Prkcg Regulation of Lpar1 1 0.12 0.58 0.72
43 INT351350 Prkaca Regulation of Lpar1 1 0.04 0.58 0.72
44 INT190984 Binding of Scn2a1 and Gria1 1 0.03 0.08 0.71
45 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
46 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
47 INT69205 Ntf3 Positive_regulation of Penk 1 0.06 0.06 0.66
48 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
49 INT28845 su Negative_regulation of Positive_regulation of Scn2a1 1 0.27 1.27 0.61
50 INT79747 Ntf3 Regulation of Positive_regulation of Ntrk1 1 0.35 0 0.6
51 INT79740 Ntf3 Regulation of Positive_regulation of Ntrk2 1 0.28 0 0.6
52 INT190987 Abat Regulation of Scn2a1 1 0.03 0.07 0.59
53 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
54 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
55 INT242602 Binding of Ntf3 and Ntrk1 1 0.10 0.14 0.57
56 INT190988 Vip Positive_regulation of Gene_expression of Scn2a1 1 0.16 0.1 0.57
57 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
58 INT101087 NTF3 Positive_regulation of Gene_expression of IKZF1 1 0.04 0.3 0.55
59 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
60 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
61 INT79746 Ntf3 Positive_regulation of Gene_expression of Sst 1 0.42 0 0.52
62 INT62055 Mbp Positive_regulation of Lta 1 0.07 1.4 0.51
63 INT108692 NTF3 Regulation of Gene_expression of IKZF1 1 0.69 0.7 0.49
64 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
65 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
66 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
67 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
68 INT96709 Ntf3 Regulation of Localization of SST 1 0.01 0 0.46
69 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
70 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
71 INT96710 Ntf3 Regulation of BDNF 1 0.02 0 0.45
72 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
73 INT335594 Myo5a Regulation of Hmmr 1 0.00 0.39 0.45
74 INT170656 Ntf3 Positive_regulation of Csf2 1 0.35 1.46 0.44
75 INT36743 NLRP3 Regulation of Mbp 1 0.01 0 0.43
76 INT170657 Ntf3 Regulation of Csf2 1 0.31 0.46 0.43
77 INT128944 Binding of Mbp and Mog 1 0.08 0.8 0.43
78 INT80824 NGF Positive_regulation of NTF3 1 0.47 0.26 0.42
79 INT60456 SCN5A Regulation of Scn2a1 1 0.00 0 0.41
80 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
81 INT72348 Mbp Positive_regulation of Localization of PRSS1 1 0.01 0.22 0.41
82 INT139654 Ntf3 Regulation of Gene_expression of Grin1 1 0.56 0.11 0.41
83 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
84 INT190977 Npy Regulation of Scn2a1 1 0.16 0 0.4
85 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
86 INT148438 Binding of Bdnf and Ntf3 1 0.33 1.14 0.4
87 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
88 INT190739 Adcyap1 Regulation of Gene_expression of Scn2a1 1 0.13 0 0.39
89 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
90 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
91 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
92 INT73537 Ntf3 Positive_regulation of Ngfr 1 0.21 0.1 0.38
93 INT137625 Ntf3 Positive_regulation of Atp7b 1 0.04 0 0.36
94 INT137438 Ntf3 Regulation of Sema3a 1 0.06 0.82 0.35
95 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
96 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
97 INT137439 Ntf3 Negative_regulation of Sema3a 1 0.02 0.77 0.34
98 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
99 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
100 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
101 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34
102 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
103 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
104 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31
105 INT296453 Binding of Gria1 and Mpdz 1 0.02 0.23 0.31
106 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
107 INT144210 Bdnf Regulation of Ntf3 1 0.20 0.78 0.3
108 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
109 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29
110 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
111 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
112 INT300552 Napa Positive_regulation of Gene_expression of TGFB1 1 0.01 0.88 0.29
113 INT144434 Gene_expression of Erbb2 Positive_regulation of ras 1 0.16 0.6 0.28
114 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
115 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
116 INT166605 Binding of BDNF and Ntf3 1 0.16 0.46 0.28
117 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
118 INT166610 Binding of BDNF and Ntf3 1 0.03 0.46 0.28
119 INT322132 Binding of Mbp and Trpv4 1 0.11 0.39 0.27
120 INT137032 Il6 Positive_regulation of Localization of Tgfb1 1 0.04 0.51 0.27
121 INT190998 ADCYAP1 Positive_regulation of Scn2a1 1 0.07 0.45 0.27
122 INT180245 Binding of Plp1 and Uchl1 1 0.03 0.47 0.27
123 INT322127 Binding of Mbp and Ca2 1 0.01 0.39 0.27
124 INT290957 Lsd Positive_regulation of Gene_expression of Egr2 1 0.11 0.1 0.26
125 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
126 INT273935 Crem Regulation of Gene_expression of Egr2 1 0.05 0.16 0.26
127 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
128 INT56056 Binding of Ntf3 and Tfg 1 0.04 0.49 0.25
129 INT114818 Try4 Positive_regulation of Afg3l2 1 0.04 0.39 0.25
130 INT348755 Plat Regulation of Gene_expression of Cldn5 1 0.10 0.45 0.25
131 INT271450 Thy1 Regulation of TGFB1 1 0.00 0.62 0.25
132 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25
133 INT56058 Negative_regulation of Binding of Ntf3 and Tfg 1 0.05 0.5 0.25
134 INT114820 TPSG1 Positive_regulation of Afg3l2 1 0.06 0.39 0.24
135 INT146217 Binding of NTF3 and Ngf 1 0.08 0.11 0.24
136 INT114819 Proc Positive_regulation of Afg3l2 1 0.07 0.39 0.24
137 INT146212 Binding of Ngf and Ntf3 1 0.00 0.11 0.24
138 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24
139 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24
140 INT328896 Scn2a1 Regulation of hb 1 0.02 0.27 0.23
141 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
142 INT168710 Ifng Regulation of TGFB1 1 0.00 0.3 0.23
143 INT318620 Mog Regulation of Mbp 1 0.05 0.85 0.23
144 INT248182 Cxcl1 Regulation of Scn8a 1 0.05 0 0.22
145 INT112596 Tgfb1 Negative_regulation of Negative_regulation of Mptp1 1 0.26 0.72 0.22
146 INT112595 Tgfb1 Negative_regulation of Gene_expression of Mptp1 1 0.27 0.72 0.22
147 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22
148 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21
149 INT180248 Binding of Gad1 and Plp1 1 0.08 0.22 0.21
150 INT144433 Gene_expression of Erbb2 Positive_regulation of Positive_regulation of Mapk3 1 0.41 0.56 0.21
151 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21
152 INT114905 TGFB1 Positive_regulation of Transcription of COL7A1 1 0.02 0.08 0.21
153 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
154 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
155 INT92692 Tgfb1 Positive_regulation of Gene_expression of Fn1 1 0.27 0.91 0.2
156 INT92693 Tgfb1 Positive_regulation of Fgf2 1 0.32 0.9 0.2
157 INT280260 Tgfb1 Positive_regulation of Cxcr1 1 0.07 1.78 0.19
158 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19
159 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
160 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
161 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
162 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
163 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
164 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
165 INT280261 Tgfb1 Positive_regulation of Gene_expression of Cxcr1 1 0.05 1.81 0.19
166 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19
167 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19
168 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18
169 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18
170 INT130932 Negative_regulation of Cpox Positive_regulation of Gene_expression of TSC1 1 0.00 0.42 0.18
171 INT351088 Negative_regulation of ERBB2 Positive_regulation of FOXO3 1 0.17 0.66 0.18
172 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18
173 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
174 INT190985 Vip Regulation of Scn2a1 1 0.09 0 0.18
175 INT222300 Binding of ERBB2 and PGR 2 0.34 1.89 0.17
176 INT273792 Cxcr2 Positive_regulation of Nfasc 1 0.08 0.29 0.17
177 INT108662 Ntf3 Positive_regulation of Trpv1 1 0.17 0.28 0.17
178 INT85334 Agtr2 Regulation of Regulation of Tgfb1 1 0.23 0.68 0.17
179 INT115610 Binding of ERBB2 and KLF1 1 0.02 2.12 0.17
180 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17
181 INT160083 TGFB1 Positive_regulation of Gene_expression of L1CAM 1 0.16 1.53 0.16
182 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
183 INT243524 Positive_regulation of Binding of NTF3 and SOX10 1 0.01 0.54 0.14
184 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14
185 INT243525 Binding of NTF3 and SOX10 1 0.01 0.54 0.14
186 INT261384 Nsdhl Negative_regulation of Gene_expression of Mbp 1 0.01 1.43 0.14
187 INT299550 TGFB1 Negative_regulation of Glul 1 0.01 0.34 0.14
188 INT230604 OLIG2 Negative_regulation of IRX3 1 0.34 0.54 0.14
189 INT175398 Binding of ERBB2 and VEGFA 2 0.16 1.34 0.13
190 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13
191 INT296031 Negative_regulation of TGFB1 Regulation of IL10 1 0.01 1.01 0.13
192 INT347868 Ntf3 Negative_regulation of Negative_regulation of Chat 1 0.03 0.22 0.13
193 INT296027 TGFB1 Regulation of TH1L 1 0.02 1 0.13
194 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13
195 INT96589 Mbp Regulation of S100B 1 0.34 0.97 0.13
196 INT330156 Scn2a1 Regulation of Transcription of Pcsk1n 1 0.13 0 0.13
197 INT299547 Negative_regulation of Binding of TGFB1 and Egf 1 0.02 0.1 0.13
198 INT69687 Tgfb1 Positive_regulation of Gene_expression of Il4 1 0.23 0 0.12
199 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12
200 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12

Single Events

The table below shows the top 100 pain related interactions that have been reported for myelination. They are ordered first by their pain relevance and then by number of times they were reported in myelination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
2 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03
3 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
4 INT20003 Gene_expression of Scn2a1 125 0.71 8.78 23.94
5 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
6 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
7 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
8 INT7580 Positive_regulation of Mbp 54 0.70 23.37 17.14
9 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
10 INT69203 Positive_regulation of Ntf3 43 0.66 19.16 16.49
11 INT14887 Gene_expression of Mbp 55 0.75 36.13 16.11
12 INT97871 Gene_expression of Ntf3 47 0.78 25.9 15.94
13 INT8634 Gene_expression of Nfasc 23 0.68 9.16 14.96
14 INT5430 Gene_expression of Scn8a 37 0.75 4.58 14.82
15 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
16 INT7465 Negative_regulation of Mbp 53 0.58 19.12 13.27
17 INT75224 Positive_regulation of Gene_expression of Ntf3 23 0.69 11.79 13.08
18 INT16256 Regulation of Ntf3 15 0.49 9.75 13.07
19 INT16255 Negative_regulation of Ntf3 21 0.51 12.92 11.93
20 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
21 INT28843 Positive_regulation of Scn2a1 31 0.68 5.35 10.7
22 INT4929 Binding of Mbp 25 0.48 18.01 9.41
23 INT8632 Regulation of Nfasc 15 0.54 2.87 9.08
24 INT8633 Negative_regulation of Gene_expression of Nfasc 1 0.51 0.6 8.79
25 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
26 INT205203 Gene_expression of Lpar1 6 0.39 11.83 8.08
27 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
28 INT71689 Localization of Ntf3 23 0.73 11.1 7.91
29 INT97870 Positive_regulation of Gene_expression of Ntf3 19 0.70 9.56 7.8
30 INT78226 Gene_expression of Mbp 43 0.75 22.14 7.79
31 INT90715 Gene_expression of Egr2 12 0.73 1.64 7.17
32 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
33 INT17674 Localization of Scn2a1 32 0.61 1.73 6.79
34 INT7464 Regulation of Mbp 25 0.62 6.62 6.43
35 INT205198 Positive_regulation of Lpar1 2 0.35 7.35 6.37
36 INT92662 Negative_regulation of Gene_expression of Ntf3 9 0.57 7.44 6.22
37 INT14486 Localization of Mbp 23 0.74 11.24 6.14
38 INT59671 Positive_regulation of Scn8a 7 0.39 1.88 5.92
39 INT8631 Negative_regulation of Nfasc 12 0.42 3.33 5.71
40 INT16257 Regulation of Gene_expression of Ntf3 8 0.43 4 5.63
41 INT760 Negative_regulation of Scn8a 11 0.42 1.65 5.6
42 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
43 INT211690 Gene_expression of Cntnap1 1 0.06 1.03 5.5
44 INT114993 Binding of Myo5a 15 0.30 11.46 5.48
45 INT103518 Negative_regulation of SCN2A 17 0.57 8.4 5.4
46 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
47 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23
48 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
49 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
50 INT351354 Localization of Lpar1 1 0.40 6.93 5.05
51 INT126505 Positive_regulation of Ntf3 26 0.70 9.17 4.92
52 INT26054 Regulation of Gene_expression of Scn8a 7 0.08 2.86 4.49
53 INT94277 Positive_regulation of Gene_expression of Egr2 7 0.49 0.69 4.4
54 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
55 INT56159 Regulation of Scn2a1 17 0.51 3.23 4.27
56 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
57 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13
58 INT61366 Positive_regulation of NFASC 16 0.26 13.75 4.11
59 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
60 INT108579 Localization of Nfasc 18 0.72 3.47 4
61 INT217102 Gene_expression of Egr2 50 0.78 10.91 3.89
62 INT75996 Transcription of Ntf3 13 0.67 4.03 3.88
63 INT86280 Positive_regulation of Nfasc 14 0.62 6.56 3.84
64 INT190722 Positive_regulation of Gene_expression of Scn2a1 15 0.36 0.5 3.78
65 INT28844 Negative_regulation of Scn2a1 15 0.37 3.84 3.65
66 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
67 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
68 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
69 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
70 INT83737 Phosphorylation of Mbp 4 0.81 1.63 3.48
71 INT233640 Negative_regulation of Olig2 5 0.54 2.02 3.47
72 INT98068 Gene_expression of SCN2A 19 0.75 14.42 3.31
73 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
74 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
75 INT39884 Negative_regulation of Mbp 23 0.56 11.93 3.21
76 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
77 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16
78 INT84021 Regulation of Mbp 8 0.57 6.79 3.09
79 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
80 INT101239 Gene_expression of NTF3 9 0.76 5.91 2.97
81 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
82 INT351355 Positive_regulation of Localization of Lpar1 1 0.25 3.94 2.87
83 INT89834 Positive_regulation of SCN2A 8 0.49 1.89 2.77
84 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
85 INT125905 Gene_expression of Cldn5 7 0.57 4.33 2.66
86 INT5863 Positive_regulation of Egr2 7 0.40 1.44 2.64
87 INT94085 Binding of NFASC 10 0.17 7.1 2.5
88 INT139169 Gene_expression of Pmp22 10 0.68 8.37 2.5
89 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
90 INT130476 Phosphorylation of Fyn 8 0.80 2.99 2.44
91 INT211684 Regulation of Gene_expression of Cntnap1 1 0.04 0.54 2.38
92 INT14907 Negative_regulation of Positive_regulation of Mbp 4 0.40 0.75 2.32
93 INT80733 Binding of Scn2a1 11 0.30 1.09 2.3
94 INT8466 Binding of Plp1 5 0.48 5.07 2.29
95 INT139648 Localization of Ntf3 7 0.66 3.73 2.22
96 INT125902 Positive_regulation of Gene_expression of Cldn5 5 0.51 3.13 2.16
97 INT98652 Positive_regulation of Localization of Ntf3 2 0.40 1.42 2.15
98 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
99 INT132383 Gene_expression of Olig2 16 0.75 5.46 2.07
100 INT62054 Transcription of Mbp 5 0.69 4.83 2.06
101 INT131638 Localization of Scn8a 2 0.53 0 1.99
102 INT90826 Localization of NFASC 8 0.17 6.01 1.97
103 INT73239 Negative_regulation of Gene_expression of Mbp 6 0.46 5.65 1.96
104 INT138878 Negative_regulation of Gene_expression of Cldn5 4 0.37 2.81 1.96
105 INT34860 Negative_regulation of Gene_expression of Scn2a1 8 0.30 0.97 1.94
106 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
107 INT217094 Positive_regulation of Egr2 17 0.69 5.31 1.87
108 INT56054 Negative_regulation of Ntf3 7 0.59 2.75 1.86
109 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
110 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8
111 INT67253 Gene_expression of Pmp22 4 0.33 6.48 1.79
112 INT231373 Negative_regulation of Pmp22 1 0.26 2.98 1.75
113 INT146387 Positive_regulation of Regulation of Mbp 1 0.43 0.25 1.71
114 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68
115 INT105200 Binding of Ntf3 6 0.31 2.46 1.67
116 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
117 INT167145 Regulation of Gene_expression of Ntf3 6 0.54 3.4 1.64
118 INT12346 Binding of Scn8a 5 0.29 0.75 1.64
119 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
120 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
121 INT133885 Binding of SCN2A 7 0.47 1.27 1.54
122 INT126504 Regulation of Ntf3 5 0.39 4.3 1.54
123 INT94083 Gene_expression of NFASC 8 0.19 4.19 1.52
124 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
125 INT52962 Binding of ERBB2 77 0.47 50.03 1.49
126 INT167085 Negative_regulation of ERBB2 67 0.57 44.6 1.48
127 INT79001 Positive_regulation of Localization of Scn2a1 3 0.36 0.22 1.48
128 INT14908 Positive_regulation of Positive_regulation of Mbp 4 0.42 0.85 1.47
129 INT107969 Negative_regulation of NFASC 6 0.24 2.58 1.44
130 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
131 INT211685 Binding of Cntnap1 1 0.04 0.18 1.42
132 INT351356 Positive_regulation of Gene_expression of Lpar1 1 0.35 1.98 1.41
133 INT211686 Positive_regulation of Positive_regulation of Scn8a 1 0.00 0.85 1.41
134 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
135 INT311241 Transcription of Myo5a 1 0.50 1.61 1.37
136 INT351361 Binding of Lpar1 1 0.18 0.96 1.35
137 INT96838 Negative_regulation of Gene_expression of ERBB2 25 0.57 15.83 1.34
138 INT214073 Binding of TSC1 9 0.37 22 1.34
139 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
140 INT81368 Binding of Ntf3 5 0.34 2.09 1.23
141 INT83736 Regulation of Phosphorylation of Mbp 2 0.53 0.47 1.22
142 INT104170 Phosphorylation of Nfasc 4 0.34 1.38 1.2
143 INT94080 Negative_regulation of Binding of NFASC 2 0.14 1.36 1.18
144 INT130477 Negative_regulation of Fyn 3 0.29 1.59 1.14
145 INT141116 Transcription of Scn2a1 9 0.45 1.1 1.1
146 INT11771 Positive_regulation of Mbp 7 0.38 2.98 1.1
147 INT231379 Negative_regulation of Negative_regulation of Pmp22 1 0.26 1.72 1.09
148 INT83842 Positive_regulation of Gene_expression of Mbp 4 0.31 1.68 1.08
149 INT146085 Negative_regulation of Positive_regulation of SCN2A 1 0.41 0.26 1.07
150 INT293487 Regulation of Gene_expression of Erbb2 4 0.61 3.4 1.06
151 INT28849 Positive_regulation of Negative_regulation of Mbp 2 0.41 1.07 1.06
152 INT48687 Gene_expression of Plp1 7 0.54 3.51 1.03
153 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
154 INT190964 Regulation of Gene_expression of Scn2a1 7 0.29 1.29 1.02
155 INT71690 Negative_regulation of Negative_regulation of Ntf3 2 0.36 1.3 1.01
156 INT130793 Positive_regulation of Gene_expression of Nfasc 1 0.02 1.76 0.99
157 INT151906 Positive_regulation of Positive_regulation of Nfasc 2 0.11 1.98 0.98
158 INT73465 Transcription of TSC1 4 0.07 3.47 0.96
159 INT57017 Transcription of Scn8a 5 0.52 0.63 0.95
160 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
161 INT55647 Binding of Nfasc 5 0.35 5.43 0.94
162 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
163 INT75994 Positive_regulation of Transcription of Ntf3 2 0.07 0.62 0.94
164 INT83738 Positive_regulation of Phosphorylation of Mbp 1 0.69 0 0.94
165 INT185261 Gene_expression of OLIG2 9 0.65 5.76 0.93
166 INT192785 Regulation of Myo5a 4 0.05 9.05 0.93
167 INT148293 Positive_regulation of Gene_expression of Pmp22 1 0.30 1.58 0.92
168 INT213917 Negative_regulation of Phosphorylation of ERBB2 9 0.54 8.68 0.91
169 INT120485 Positive_regulation of Plp1 1 0.33 2.2 0.9
170 INT204825 Negative_regulation of Plp1 3 0.33 2.96 0.87
171 INT190396 Positive_regulation of Gene_expression of Scn8a 2 0.45 0.77 0.86
172 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
173 INT18917 Regulation of Negative_regulation of Scn8a 1 0.23 0 0.86
174 INT88718 Negative_regulation of Erbb2 11 0.58 12.98 0.84
175 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
176 INT71649 Localization of ERBB2 23 0.78 13.63 0.83
177 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
178 INT92623 Regulation of Positive_regulation of Ntf3 2 0.09 1 0.83
179 INT146940 Gene_expression of Fyn 2 0.52 2.76 0.83
180 INT176588 Phosphorylation of ERBB2 27 0.78 16.37 0.81
181 INT45960 Negative_regulation of Gene_expression of Scn8a 2 0.42 0.4 0.81
182 INT74019 Regulation of TSC1 27 0.35 23.61 0.79
183 INT251063 Gene_expression of Cldn5 12 0.59 3.73 0.79
184 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
185 INT57958 Positive_regulation of Myo5a 9 0.41 7.52 0.77
186 INT291617 Negative_regulation of Transcription of TGFB1 2 0.15 0.61 0.76
187 INT90790 Regulation of Localization of Tgfb1 2 0.29 0.46 0.75
188 INT87758 Negative_regulation of Regulation of Nfasc 1 0.42 0 0.75
189 INT81396 Regulation of Gene_expression of ERBB2 14 0.43 10.73 0.74
190 INT82117 Phosphorylation of NFASC 2 0.46 1.82 0.72
191 INT351359 Negative_regulation of Lpar1 1 0.22 1.21 0.72
192 INT240519 Regulation of Scn8a 3 0.06 0.9 0.71
193 INT94300 Negative_regulation of Gene_expression of Mbp 6 0.44 1.79 0.7
194 INT147212 Negative_regulation of Gene_expression of Egr2 1 0.38 0.1 0.7
195 INT337046 Positive_regulation of Binding of Tgfb1 1 0.30 1.1 0.69
196 INT96704 Negative_regulation of Positive_regulation of Ntf3 2 0.37 0 0.68
197 INT121302 Positive_regulation of Localization of Tgfb1 5 0.07 1.91 0.67
198 INT90718 Regulation of Gene_expression of Egr2 2 0.43 0.41 0.67
199 INT211693 Regulation of Regulation of Cntnap1 1 0.04 0 0.67
200 INT114909 Negative_regulation of Localization of TGFB1 5 0.36 1.37 0.66
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