GO:0042558

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Name pteridine-containing compound metabolic process
Categary Process
Go Slim No
Go Link GO:0042558
Unique Molecular Interactions 42
Total Molecular Interactions 58
Total Single Events 387
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for pteridine-containing compound metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for pteridine-containing compound metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
2 INT27425 Mtr Positive_regulation of Gene_expression of Il1f5 1 0.06 0 1.3
3 INT61687 Binding of Pah and Slc3a1 1 0.00 0.11 1.09
4 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
5 INT107563 Penk Regulation of Mtr 1 0.00 0.1 1.04
6 INT107565 Hps4 Regulation of Mtr 1 0.00 0.1 1.04
7 INT91273 Mtr Positive_regulation of Localization of Il6 1 0.17 0 0.88
8 INT188318 MCPH1 Positive_regulation of Pah 3 0.02 3 0.85
9 INT54669 Mtr Regulation of Gene_expression of Il1 1 0.02 0.2 0.77
10 INT54668 Mtr Regulation of Gene_expression of Il1f5 1 0.00 0.2 0.76
11 INT45822 Pah Positive_regulation of Localization of Ins1 1 0.01 0.3 0.73
12 INT46657 Mtr Regulation of Gnrh1 1 0.01 0 0.71
13 INT46656 Mtr Regulation of Prl 1 0.05 0 0.7
14 INT38820 Binding of MTR and PDYN 1 0.03 0.19 0.65
15 INT27426 Mtr Positive_regulation of Localization of Il1f5 1 0.06 0 0.63
16 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61
17 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6
18 INT50935 Mtr Regulation of Gene_expression of Il6 1 0.00 0 0.53
19 INT28863 Mtr Negative_regulation of Dhfr 1 0.04 0.87 0.45
20 INT43587 Binding of OPRD1 and Pah 1 0.00 0.08 0.43
21 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
22 INT303005 Binding of Ednra and Pah 1 0.06 1.02 0.32
23 INT50934 Mtr Positive_regulation of Gene_expression of Il6 1 0.00 0 0.2
24 INT160515 Negative_regulation of Sert1 Negative_regulation of Pah 1 0.34 0.84 0.19
25 INT47164 Binding of Asap1 and Pah 1 0.27 0.07 0.17
26 INT303028 Binding of Pah and MCPH1 1 0.02 1.13 0.16
27 INT303003 Gene_expression of Ptgis Positive_regulation of Pah 1 0.36 1.67 0.13
28 INT303007 Binding of Pah and Ptgis 1 0.26 0.99 0.12
29 INT249923 Binding of Pah and Hif1a 1 0.31 1.16 0.12
30 INT249925 Cpox Negative_regulation of Pah 1 0.01 0.18 0.1
31 INT249920 Negative_regulation of Binding of Pah and Hif1a 1 0.37 0.76 0.08
32 INT273616 PVR Positive_regulation of Pah 1 0.10 0.86 0.07
33 INT245985 Binding of MTR and Mtrr 1 0.06 0.8 0.07
34 INT303027 Gene_expression of MCPH1 Positive_regulation of Pah 1 0.02 0.83 0.07
35 INT245986 MTR Regulation of Mthfr 1 0.07 0.18 0.05
36 INT245966 TCN1 Regulation of MTR 1 0.02 0.18 0.05
37 INT245967 Negative_regulation of TCN1 Regulation of MTR 1 0.02 0.18 0.05
38 INT249922 Binding of Pah and Asph 1 0.06 0.4 0.04
39 INT303008 Gene_expression of Pah Positive_regulation of Gene_expression of Ptgis 1 0.31 0.78 0.04
40 INT245987 Binding of MTR and Mthfr 1 0.11 0.48 0.03
41 INT313871 Pde5a Positive_regulation of Pah 1 0.49 0.97 0
42 INT309846 Binding of pad and Pah 1 0.03 0.98 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for pteridine-containing compound metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in pteridine-containing compound metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1672 Gene_expression of Mtr 18 0.67 3.39 13.32
2 INT22965 Positive_regulation of Pah 42 0.61 41.41 8.84
3 INT18025 Binding of Pah 32 0.45 30.72 7.93
4 INT9802 Positive_regulation of Mtr 9 0.60 3.69 7.43
5 INT32783 Gene_expression of Pah 33 0.60 30.55 6.86
6 INT46518 Localization of Mtr 12 0.65 1.31 6.55
7 INT49468 Negative_regulation of Pah 28 0.55 24.95 6.29
8 INT10006 Regulation of Mtr 9 0.23 3.56 5.42
9 INT12250 Negative_regulation of Mtr 19 0.50 6.9 5.35
10 INT9803 Positive_regulation of Gene_expression of Mtr 3 0.60 1.45 4.36
11 INT24751 Gene_expression of Mtr 8 0.36 1.34 3.34
12 INT42485 Binding of Pah 9 0.35 3.42 3.03
13 INT29651 Regulation of Pah 11 0.37 9.95 2.79
14 INT61685 Positive_regulation of Gene_expression of Pah 6 0.43 4.05 1.79
15 INT25582 Regulation of Mtr 2 0.03 0.4 1.76
16 INT22966 Negative_regulation of Positive_regulation of Pah 2 0.50 2.03 1.56
17 INT47446 Regulation of Localization of Mtr 1 0.05 0.07 1.42
18 INT9217 Negative_regulation of MTR 17 0.58 1.13 1.32
19 INT49466 Negative_regulation of Binding of Pah 2 0.37 0.34 1.24
20 INT2595 Binding of Mtr 1 0.29 0 1.24
21 INT47131 Negative_regulation of Localization of Mtr 1 0.41 0 1.06
22 INT157361 Localization of MTR 2 0.31 1.4 1.05
23 INT24750 Negative_regulation of Mtr 1 0.22 0.06 1.04
24 INT66485 Negative_regulation of Binding of Pah 2 0.35 1.27 0.83
25 INT36978 Localization of Pah 9 0.73 7.43 0.82
26 INT24584 Positive_regulation of MTR 4 0.44 0.07 0.7
27 INT249912 Positive_regulation of Negative_regulation of Pah 2 0.43 2.49 0.64
28 INT10007 Regulation of Gene_expression of Mtr 2 0.23 1.17 0.61
29 INT14109 Positive_regulation of Mtr 1 0.03 0.49 0.6
30 INT160514 Regulation of Positive_regulation of Pah 1 0.22 1.62 0.45
31 INT24583 Protein_catabolism of MTR 1 0.57 0 0.42
32 INT54952 Binding of Mtr 1 0.03 0.58 0.37
33 INT303025 Negative_regulation of Negative_regulation of Pah 1 0.28 1.03 0.34
34 INT26194 Regulation of MTR 1 0.19 1.1 0.33
35 INT166893 Negative_regulation of Gene_expression of Mtr 1 0.03 0.57 0.33
36 INT282213 Negative_regulation of Regulation of Mtr 1 0.01 0.82 0.27
37 INT273611 Positive_regulation of Localization of Pah 1 0.40 0.75 0.24
38 INT313869 Gene_expression of Pah 4 0.63 3.1 0.23
39 INT70913 Gene_expression of MTR 2 0.12 0.44 0.21
40 INT36979 Negative_regulation of Localization of Pah 1 0.39 0.5 0.2
41 INT223333 Negative_regulation of Gene_expression of MTR 1 0.07 0.16 0.16
42 INT55773 Binding of MTR 2 0.30 0.74 0.14
43 INT230729 Regulation of Gene_expression of Pah 1 0.24 1 0.13
44 INT230730 Negative_regulation of Gene_expression of Pah 2 0.28 1.54 0.12
45 INT188304 Positive_regulation of Positive_regulation of Pah 1 0.18 0.75 0.09
46 INT12251 Regulation of Negative_regulation of Mtr 1 0.19 0 0.09
47 INT313868 Positive_regulation of Pah 2 0.41 0.67 0.08
48 INT313866 Positive_regulation of Positive_regulation of Pah 1 0.41 0.47 0.08
49 INT55772 Negative_regulation of Negative_regulation of MTR 1 0.41 0 0.07
50 INT303023 Protein_catabolism of Pah 1 0.43 2.06 0.06
51 INT313865 Positive_regulation of Gene_expression of Pah 2 0.47 0.95 0.05
52 INT288754 Negative_regulation of Positive_regulation of Mtr 1 0.11 0.1 0.05
53 INT270748 Regulation of Regulation of Pah 1 0.04 1.61 0.04
54 INT288765 Positive_regulation of Negative_regulation of Mtr 1 0.12 0.09 0.04
55 INT47058 Positive_regulation of Negative_regulation of MTR 1 0.41 0 0
56 INT47059 Positive_regulation of Positive_regulation of MTR 1 0.44 0 0
57 INT313870 Negative_regulation of Pah 1 0.48 2.33 0
58 INT328696 Negative_regulation of Gene_expression of Pah 1 0.16 0 0
59 INT303017 Regulation of Localization of Pah 1 0.29 0.85 0
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