GO:0042562

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Name hormone binding
Categary Function
Go Slim No
Go Link GO:0042562
Unique Molecular Interactions 513
Total Molecular Interactions 675
Total Single Events 6392
Pain Genes Associated 34

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hormone binding. They are ordered first by their pain relevance and then by number of times they were reported for hormone binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
2 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
3 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
4 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57
5 INT33756 Akr1d1 Positive_regulation of Npr1 3 0.01 0 2.05
6 INT21261 Penk Negative_regulation of Npr1 1 0.02 0 2
7 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
8 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
9 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
10 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
11 INT33757 Hmmr Positive_regulation of Npr1 1 0.01 0 1.59
12 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
13 INT19013 Ghsr Negative_regulation of Localization of Sst 1 0.15 0 1.44
14 INT19012 Ghsr Negative_regulation of Localization of Sstr1 1 0.10 0 1.44
15 INT6466 Binding of Npr1 and Oprd1 1 0.01 0 1.37
16 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
17 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
18 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
19 INT143620 Ltp Positive_regulation of Npr1 1 0.01 0.16 1.26
20 INT42554 Oprl1 Regulation of Npr1 2 0.06 0 1.22
21 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
22 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
23 INT13205 Oprd1 Negative_regulation of Npr1 2 0.01 0 1.16
24 INT13204 Binding of Npr1 and Akr1d1 1 0.00 0 1.14
25 INT7024 Regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.07 1.13
26 INT33142 Pck1 Positive_regulation of Npr1 4 0.01 0.5 1.02
27 INT13502 Penk Positive_regulation of Npr1 1 0.02 0.19 1.01
28 INT13503 Regulation of Penk Positive_regulation of Npr1 1 0.02 0.19 1.01
29 INT7025 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.04 0.08 1.01
30 INT42555 Oprl1 Negative_regulation of Npr1 1 0.02 0 0.99
31 INT140068 Binding of GH1 and Ghsr 1 0.00 0.47 0.97
32 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
33 INT279166 Binding of Cyp3a23/3a1 and Nr3c2 1 0.00 0.61 0.9
34 INT295552 Binding of Ghrl and Ghsr 7 0.40 1.64 0.88
35 INT111790 Penk Regulation of Gene_expression of Npr1 1 0.22 0.56 0.86
36 INT105970 GH1 Regulation of Ghsr 1 0.04 1.16 0.84
37 INT129881 Binding of Calr and Cbll1 1 0.00 0.58 0.84
38 INT41156 Sst Negative_regulation of Npr1 1 0.05 0 0.84
39 INT29781 PDYN Negative_regulation of Npr1 1 0.00 0.22 0.84
40 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
41 INT108811 Esr2 Positive_regulation of Binding of Oprm1 1 0.46 0.44 0.79
42 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
43 INT295546 Ghrl Positive_regulation of Ghsr 3 0.39 0.09 0.77
44 INT298457 Binding of Calca and Npr1 1 0.01 0.39 0.77
45 INT353721 Negative_regulation of Binding of Drd1a and Ghsr 1 0.16 0 0.76
46 INT353720 Binding of Drd1a and Ghsr 1 0.18 0 0.76
47 INT21260 Positive_regulation of Drd1a Positive_regulation of Npr1 1 0.05 0 0.76
48 INT353718 Binding of Rbm39 and Ghsr 1 0.01 0 0.76
49 INT147619 Npr1 Positive_regulation of Localization of Calca 1 0.03 0 0.75
50 INT57658 ASNA1 Positive_regulation of Npr1 1 0.00 0.15 0.74
51 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
52 INT169603 Nppb Regulation of Npr1 1 0.26 0.95 0.69
53 INT71988 Drd1a Regulation of Npr1 1 0.10 0 0.68
54 INT291548 Binding of Gper and Sec22b 1 0.02 0.94 0.67
55 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
56 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
57 INT6464 Sst Regulation of Negative_regulation of Npr1 1 0.01 0 0.64
58 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64
59 INT6463 Oprd1 Regulation of Negative_regulation of Npr1 1 0.01 0 0.63
60 INT6465 Trh Regulation of Negative_regulation of Npr1 1 0.01 0 0.63
61 INT231027 LOC100366054 Negative_regulation of Gene_expression of Pgr 1 0.02 0 0.62
62 INT19011 Binding of Ghrh and Ghsr 1 0.40 0 0.62
63 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
64 INT109802 Binding of Esr2 and Oprl1 1 0.22 0.1 0.59
65 INT97655 Binding of RBM25 and Mc1r 1 0.00 0.44 0.58
66 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
67 INT166214 Binding of CTS and TTR 1 0.13 1.63 0.55
68 INT231034 Sec22b Positive_regulation of Gene_expression of Pgr 1 0.04 0.09 0.53
69 INT43075 Slc6a14 Regulation of Positive_regulation of Npr1 1 0.01 0 0.51
70 INT43076 Slc6a14 Regulation of Npr1 1 0.01 0 0.51
71 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
72 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
73 INT130335 Binding of Mc4r and Nr3c2 1 0.06 1.87 0.5
74 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
75 INT140067 GH1 Positive_regulation of Ghsr 1 0.00 0.23 0.49
76 INT140066 Ghsr Positive_regulation of GH1 1 0.00 0.23 0.48
77 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
78 INT55265 Ptgdr Negative_regulation of Npr1 1 0.01 0 0.46
79 INT52679 Positive_regulation of Npr1 Positive_regulation of Positive_regulation of VSX1 1 0.00 0 0.45
80 INT325391 Binding of Ghrl and Ghsr 2 0.17 0.14 0.43
81 INT323484 Ghsr Positive_regulation of Localization of Ins1 1 0.27 0.87 0.43
82 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42
83 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41
84 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
85 INT346151 Binding of ADM and GPER 1 0.01 0.99 0.41
86 INT49716 PCA Negative_regulation of Nr3c2 1 0.02 0 0.41
87 INT264522 Binding of GPER and PTGDS 1 0.03 1.22 0.4
88 INT131353 Binding of Npr1 and Nppb 1 0.27 1.73 0.4
89 INT131356 Binding of Nppa and Npr1 1 0.27 1.73 0.4
90 INT57649 Oprd1 Positive_regulation of Npr1 1 0.01 0.1 0.39
91 INT95999 Binding of Npr1 and Cnr1 1 0.05 0 0.39
92 INT122188 Binding of Crh and Ucn2 2 0.22 0.29 0.38
93 INT117361 Binding of Esr1 and sea 1 0.02 1.38 0.38
94 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
95 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
96 INT169604 Nppb Positive_regulation of Npr1 2 0.52 2.52 0.37
97 INT117359 Binding of Esr1 and Wbc1 1 0.00 1.38 0.37
98 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37
99 INT265015 Pgr Positive_regulation of Sds 1 0.04 0.49 0.37
100 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37
101 INT122189 Binding of Crhr1 and Ucn2 2 0.08 0.27 0.36
102 INT291555 Binding of ESR1 and Dlat 1 0.01 0.6 0.35
103 INT291554 Binding of ESR1 and St8sia2 1 0.01 0.49 0.33
104 INT291543 Binding of Dlat and Gper 1 0.15 0.37 0.33
105 INT39594 TPO Positive_regulation of CALR 1 0.30 0.91 0.32
106 INT350214 Binding of GPER and HSPG2 1 0.00 0.12 0.32
107 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
108 INT235884 Htr3a Regulation of Nr3c1 1 0.00 0.63 0.32
109 INT336936 Binding of GSR and Nr3c2 1 0.06 2.29 0.31
110 INT115261 Gene_expression of Nos2 Positive_regulation of Positive_regulation of Npr1 1 0.05 0.67 0.31
111 INT336933 Binding of Nr3c2 and Ugcg 1 0.07 2.3 0.31
112 INT309156 Esr1 Regulation of Gene_expression of Dlat 1 0.05 1.06 0.3
113 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
114 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
115 INT83750 Gh1 Regulation of Gene_expression of Ghsr 1 0.36 0 0.29
116 INT295549 Ghrl Positive_regulation of Gene_expression of Ghsr 1 0.29 0 0.29
117 INT96436 Binding of Npr1 and Oprl1 1 0.05 0 0.29
118 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
119 INT327366 Binding of Fap and Ttr 1 0.33 2.9 0.28
120 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
121 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
122 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
123 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27
124 INT49717 PCA Regulation of Nr3c2 1 0.01 0 0.27
125 INT208499 Positive_regulation of Nkx1-1 Positive_regulation of Npr1 1 0.00 0 0.27
126 INT149358 Binding of Oprm1 and Positive_regulation of Positive_regulation of Npr1 1 0.00 0.09 0.26
127 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
128 INT245640 Nr3c2 Regulation of Positive_regulation of Hpse 1 0.08 0.66 0.26
129 INT47012 Regulation of Pck1 Positive_regulation of Npr1 1 0.01 0 0.26
130 INT54263 Ghsr Regulation of Localization of Gh1 1 0.23 0 0.26
131 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26
132 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25
133 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
134 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25
135 INT182349 Binding of Ms4a1 and Esr1 1 0.04 1.26 0.25
136 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24
137 INT309160 Binding of Esr1 and Edc4 1 0.03 0.34 0.24
138 INT210803 Igh-Dex Regulation of Nr3c1 1 0.05 0 0.24
139 INT318980 Binding of CALR and Positive_regulation of Localization of GOPC 1 0.04 0.32 0.24
140 INT197590 Esr2 Positive_regulation of Negative_regulation of Pgr 1 0.16 0 0.24
141 INT159163 Binding of Esr2 and Regulation of Gper 1 0.41 0.27 0.23
142 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
143 INT279961 CSF2 Negative_regulation of TTR 1 0.04 1.07 0.23
144 INT261389 Nsdhl Positive_regulation of Esr2 1 0.06 1.04 0.23
145 INT63198 POMC Positive_regulation of ESR1 1 0.14 0.3 0.23
146 INT270135 Binding of ESR1 and RALA 1 0.11 0.37 0.22
147 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
148 INT131355 Npr1 Regulation of Nppb 1 0.39 0.88 0.22
149 INT131354 Npr1 Regulation of Nppa 1 0.40 0.88 0.22
150 INT35211 Ghsr Positive_regulation of Localization of Gh1 5 0.31 0 0.21
151 INT308645 Binding of Esr1 and Itpr3 1 0.00 0 0.2
152 INT25089 Glul Positive_regulation of Npr1 1 0.00 0 0.2
153 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19
154 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19
155 INT316203 Ghsr Positive_regulation of Transcription of Agrp 1 0.02 1.5 0.19
156 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
157 INT55809 Binding of Ttr and Fap 1 0.12 2.56 0.19
158 INT197618 Binding of Esr1 and Ppt1 1 0.01 0 0.18
159 INT52306 Nr3c1 Negative_regulation of Transcription of Penk 1 0.26 0 0.18
160 INT173932 Binding of Esr1 and Il6 1 0.03 0.11 0.18
161 INT256586 Binding of RBP4 and TTR 1 0.07 1.92 0.18
162 INT154355 Binding of Nppc and Npr1 1 0.19 0.43 0.18
163 INT29959 Ahsp Positive_regulation of Npr1 1 0.00 0.18 0.17
164 INT19042 ESR1 Positive_regulation of GGT5 1 0.03 0.6 0.17
165 INT19045 ESR1 Positive_regulation of Salpa1 1 0.02 0.6 0.17
166 INT245641 Nr3c2 Regulation of Gene_expression of Hpse 1 0.14 2.67 0.17
167 INT18043 Binding of SIGMAR1 and Pgr 1 0.00 0.06 0.16
168 INT33141 Pck1 Regulation of Npr1 1 0.00 0.17 0.16
169 INT183214 Binding of gr and Nr3c2 1 0.04 0.31 0.16
170 INT310595 Ros1 Positive_regulation of Npr1 1 0.03 0.84 0.16
171 INT354114 Binding of CALR and SST 1 0.01 0.1 0.16
172 INT251435 Gnat3 Positive_regulation of NPR1 1 0.22 0.2 0.15
173 INT83748 Ghsr Positive_regulation of Gene_expression of Fos 1 0.27 0 0.15
174 INT309154 Esr1 Positive_regulation of Gsdmc 1 0.01 0.44 0.15
175 INT266036 Gpr30 Positive_regulation of Positive_regulation of Mapk1 1 0.19 0.24 0.15
176 INT309155 Negative_regulation of Esr1 Positive_regulation of Gsdmc 1 0.01 0.45 0.15
177 INT85816 Binding of CEL and TTR 1 0.39 0.77 0.14
178 INT181752 Binding of CPOX and ESR1 1 0.02 0.89 0.14
179 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14
180 INT17523 Ghsr Positive_regulation of Localization of Gh 2 0.02 0.24 0.13
181 INT173404 GPER Regulation of Itgam 1 0.02 0.41 0.13
182 INT297312 Esr1 Positive_regulation of Scap 1 0.00 1.58 0.13
183 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13
184 INT86429 Binding of Hspb1 and Esr1 1 0.19 0.26 0.13
185 INT173373 GPER Regulation of FCGR3B 1 0.03 0.39 0.12
186 INT236588 Binding of Esr1 and Ins1 1 0.05 0.73 0.12
187 INT171792 GPER Regulation of Gene_expression of Itga2 1 0.00 0.54 0.12
188 INT128551 Binding of Cebpb and Nr3c1 1 0.06 0.15 0.11
189 INT122192 Binding of Crhr2 and Ucn2 1 0.02 0.23 0.11
190 INT341827 Binding of ESR1 and TNC 1 0.14 0.63 0.11
191 INT341775 DBT Regulation of Binding of ESR1 1 0.02 0.1 0.11
192 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11
193 INT295528 Ghsr Positive_regulation of Gene_expression of Fos 1 0.61 0 0.11
194 INT171791 GPER Negative_regulation of Gene_expression of Itgam 1 0.02 0.46 0.11
195 INT220114 Tnfrsf1a Positive_regulation of Esr1 1 0.14 1.14 0.1
196 INT25090 Negative_regulation of Glul Positive_regulation of Npr1 1 0.00 0 0.1
197 INT151136 MC1R Regulation of Mchr1 1 0.00 0.43 0.1
198 INT237819 Binding of Esr1 and soc 1 0.04 0 0.1
199 INT43284 Binding of Npr1 and Gcg 1 0.05 0 0.1
200 INT96563 Binding of ADRA1D and UCN2 1 0.19 1.34 0.1

Single Events

The table below shows the top 100 pain related interactions that have been reported for hormone binding. They are ordered first by their pain relevance and then by number of times they were reported in hormone binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78
2 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11
3 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
4 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
5 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
6 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
7 INT37296 Binding of Esr1 117 0.43 62.51 27.33
8 INT20462 Binding of ESR1 210 0.44 102.7 26.34
9 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
10 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19
11 INT7573 Positive_regulation of Nr3c2 38 0.67 20 21.84
12 INT7017 Regulation of Npr1 45 0.52 3.38 20.05
13 INT4260 Negative_regulation of Positive_regulation of Npr1 29 0.43 4.39 19.57
14 INT6461 Gene_expression of Npr1 35 0.75 10.38 17.58
15 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
16 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
17 INT9299 Positive_regulation of Positive_regulation of Npr1 32 0.53 6.65 16.72
18 INT92354 Localization of ESR1 77 0.75 33.04 15.51
19 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
20 INT8989 Binding of Npr1 25 0.36 5.52 14.58
21 INT12321 Binding of Nr3c2 19 0.46 5.44 13.46
22 INT2038 Localization of Esr1 104 0.79 40.12 13.27
23 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
24 INT12315 Gene_expression of Nr3c2 37 0.75 19.28 11.97
25 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7
26 INT7577 Regulation of Nr3c2 16 0.56 7.7 10.1
27 INT13606 Negative_regulation of Negative_regulation of Npr1 13 0.40 1.21 10.01
28 INT26487 Positive_regulation of Npr1 17 0.70 10.01 8.78
29 INT26751 Regulation of Nr3c1 13 0.61 6.58 8.65
30 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
31 INT49749 Negative_regulation of Nr3c1 13 0.43 6.25 7.36
32 INT31333 Gene_expression of Esr2 19 0.69 8.78 6.83
33 INT26489 Negative_regulation of Npr1 15 0.59 5.7 6.79
34 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
35 INT12314 Negative_regulation of Nr3c2 16 0.56 14.82 6.72
36 INT96218 Positive_regulation of Pgr 17 0.68 5.23 6.57
37 INT6891 Binding of TTR 72 0.48 22.81 6.51
38 INT6459 Regulation of Negative_regulation of Npr1 10 0.53 0.16 6.44
39 INT7021 Positive_regulation of Negative_regulation of Npr1 8 0.22 1.02 6.36
40 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
41 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25
42 INT6195 Transcription of Npr1 9 0.69 3 5.94
43 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
44 INT7018 Positive_regulation of Gene_expression of Npr1 10 0.59 5.09 5.66
45 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
46 INT64450 Gene_expression of Mc1r 13 0.77 9.22 5.43
47 INT13706 Localization of Npr1 10 0.59 0.83 5.42
48 INT52814 Negative_regulation of Nr3c1 9 0.57 5.69 5.41
49 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38
50 INT18661 Localization of Ghsr 32 0.78 3.19 5.2
51 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
52 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78
53 INT37652 Positive_regulation of Pgr 29 0.59 9.09 4.67
54 INT149091 Gene_expression of Ghsr 42 0.76 5.11 4.6
55 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
56 INT97264 Binding of Mc1r 9 0.36 4.27 4.53
57 INT55552 Regulation of Gene_expression of Nr3c2 5 0.59 5.93 4.53
58 INT88947 Positive_regulation of Gene_expression of Pgr 22 0.64 7 4.39
59 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
60 INT49712 Regulation of Nr3c1 10 0.28 5.65 4.06
61 INT77385 Gene_expression of Esr2 18 0.75 4.69 3.92
62 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
63 INT25200 Positive_regulation of GPER 13 0.05 1.75 3.67
64 INT20461 Binding of Esr1 34 0.48 9.58 3.66
65 INT131165 Positive_regulation of Gene_expression of Nr3c1 8 0.70 7.18 3.44
66 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
67 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
68 INT7571 Transcription of Nr3c2 6 0.58 2.15 3.03
69 INT10553 Regulation of GPER 13 0.15 2.12 3.02
70 INT132760 Gene_expression of Pgr 47 0.66 28.17 2.85
71 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
72 INT54449 Positive_regulation of Transcription of Npr1 3 0.45 1.73 2.81
73 INT99104 Gene_expression of Npr1 5 0.78 3.31 2.8
74 INT19009 Positive_regulation of Ghsr 17 0.64 5.71 2.78
75 INT174727 Positive_regulation of Positive_regulation of ESR1 14 0.44 6.3 2.7
76 INT77250 Positive_regulation of Gene_expression of Nr3c1 4 0.44 3.32 2.64
77 INT136105 Regulation of Pgr 4 0.45 1.93 2.62
78 INT7574 Positive_regulation of Transcription of Nr3c2 4 0.54 1.26 2.52
79 INT26205 Positive_regulation of Positive_regulation of NPR1 3 0.24 1.57 2.52
80 INT110284 Negative_regulation of Positive_regulation of Nr3c2 4 0.53 2.08 2.48
81 INT54555 Negative_regulation of CALR 10 0.41 4.41 2.4
82 INT8484 Localization of Nr3c1 8 0.53 3.12 2.32
83 INT11065 Gene_expression of NPR1 6 0.55 3.41 2.32
84 INT39212 Binding of Ttr 14 0.48 9.62 2.31
85 INT54615 Gene_expression of GPER 25 0.75 8.23 2.27
86 INT22605 Regulation of Pgr 22 0.62 7.1 2.26
87 INT178632 Regulation of Gene_expression of Pgr 11 0.35 1.56 2.26
88 INT35210 Gene_expression of Ghsr 39 0.75 6 2.24
89 INT13267 Binding of Pgr 15 0.40 3.5 2.22
90 INT55365 Regulation of Binding of Nr3c2 2 0.56 0.85 2.2
91 INT55364 Negative_regulation of Binding of Nr3c2 2 0.39 0.87 2.17
92 INT6460 Regulation of Gene_expression of Npr1 4 0.52 2.19 2.13
93 INT112050 Regulation of Mc1r 5 0.45 1.36 2.1
94 INT99039 Negative_regulation of Gene_expression of Nr3c1 2 0.37 1.96 2.08
95 INT323480 Negative_regulation of Ghsr 4 0.36 0.9 2.06
96 INT56342 Gene_expression of TTR 34 0.78 16.5 2.05
97 INT135692 Localization of Nr3c2 7 0.77 4.14 1.98
98 INT70526 Binding of CALR 11 0.35 7.09 1.97
99 INT21941 Regulation of CALR 7 0.53 3.88 1.96
100 INT44223 Positive_regulation of TTR 10 0.70 10.98 1.95
101 INT135313 Regulation of Gene_expression of Nr3c1 3 0.39 3.44 1.94
102 INT109800 Binding of Esr2 8 0.42 1.79 1.93
103 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92
104 INT52305 Binding of Nr3c1 7 0.15 3.95 1.9
105 INT218959 Negative_regulation of Protein_catabolism of ESR1 3 0.37 0.97 1.9
106 INT167456 Regulation of Gene_expression of Nr3c1 2 0.14 0.76 1.87
107 INT90315 Positive_regulation of Gene_expression of Nr3c2 4 0.55 2 1.83
108 INT33845 Binding of GPER 20 0.36 5.61 1.81
109 INT14413 Regulation of Positive_regulation of Npr1 7 0.62 0.71 1.78
110 INT94163 Negative_regulation of UCN2 11 0.57 6.86 1.75
111 INT26750 Positive_regulation of Nr3c1 6 0.46 5.46 1.75
112 INT11098 Regulation of NPR1 5 0.37 1.39 1.74
113 INT96216 Negative_regulation of Positive_regulation of Pgr 2 0.37 0.74 1.72
114 INT153918 Binding of Esr2 3 0.33 2.56 1.7
115 INT96971 Positive_regulation of Gene_expression of Esr1 6 0.46 2.27 1.67
116 INT43045 Negative_regulation of Regulation of Npr1 3 0.12 0.17 1.65
117 INT30076 Negative_regulation of Esr2 1 0.01 0 1.63
118 INT12890 Gene_expression of Ttr 15 0.63 7.68 1.6
119 INT19007 Binding of Ghsr 5 0.46 0.46 1.6
120 INT98687 Gene_expression of Calr 38 0.61 7.03 1.59
121 INT222089 Positive_regulation of Localization of Esr1 19 0.49 8.73 1.58
122 INT132761 Negative_regulation of Pgr 6 0.50 3.07 1.58
123 INT45711 Localization of Pgr 7 0.61 1.27 1.56
124 INT26488 Regulation of Npr1 4 0.39 0.88 1.56
125 INT49448 Positive_regulation of Positive_regulation of Nr3c1 1 0.38 0 1.55
126 INT87361 Negative_regulation of TTR 25 0.57 5.74 1.51
127 INT31921 Negative_regulation of Localization of Npr1 2 0.17 0 1.51
128 INT7578 Transcription of Nr3c1 5 0.32 0.43 1.47
129 INT6194 Regulation of Transcription of Npr1 2 0.05 0.08 1.46
130 INT96324 Negative_regulation of Gene_expression of Nr3c2 3 0.56 1.01 1.43
131 INT67465 Positive_regulation of Regulation of Npr1 1 0.05 0.14 1.4
132 INT125679 Gene_expression of Mchr1 1 0.64 0 1.3
133 INT158078 Gene_expression of Gper 7 0.67 1.13 1.26
134 INT8511 Localization of Esr1 6 0.80 3.27 1.26
135 INT66118 Binding of Calr 4 0.46 1.46 1.26
136 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25
137 INT245636 Regulation of Positive_regulation of Nr3c2 2 0.59 1.55 1.25
138 INT128752 Negative_regulation of Localization of Esr1 11 0.43 4.8 1.23
139 INT97474 Positive_regulation of UCN2 6 0.67 1.85 1.23
140 INT78355 Negative_regulation of Gene_expression of Npr1 2 0.06 0.15 1.22
141 INT11099 Localization of NPR1 5 0.67 1.49 1.21
142 INT17032 Positive_regulation of Ttr 7 0.50 3.87 1.2
143 INT23767 Positive_regulation of SERPINA7 6 0.67 1.96 1.2
144 INT89756 Positive_regulation of Positive_regulation of Npr1 2 0.47 0.9 1.19
145 INT94162 Binding of UCN2 3 0.36 1.8 1.18
146 INT824 Negative_regulation of Negative_regulation of ESR1 3 0.42 1.53 1.18
147 INT40170 Regulation of Localization of Npr1 2 0.05 0.12 1.16
148 INT81136 Binding of Npr1 6 0.48 1.45 1.15
149 INT159162 Binding of Gper 2 0.48 1.69 1.12
150 INT57852 Regulation of Ghsr 15 0.59 1.02 1.1
151 INT149090 Positive_regulation of Ghsr 10 0.70 2.33 1.06
152 INT81945 Negative_regulation of Binding of Esr1 3 0.32 0.55 1.06
153 INT27938 Negative_regulation of Pgr 12 0.38 1.98 1.05
154 INT118984 Negative_regulation of Mc1r 1 0.53 1.19 1.05
155 INT144767 Gene_expression of UCN2 5 0.65 1.78 1.04
156 INT158077 Regulation of Gper 2 0.35 0.91 1.04
157 INT91776 Negative_regulation of Gene_expression of Nr3c1 4 0.42 2.26 1.03
158 INT66862 Regulation of Esr2 3 0.24 1.56 1.01
159 INT118985 Negative_regulation of Gene_expression of Mc1r 5 0.53 1.01 1
160 INT46320 Negative_regulation of Ttr 4 0.15 2.54 1
161 INT157531 Gene_expression of Gpr30 2 0.53 1.12 0.99
162 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98
163 INT158737 Localization of Pgr 4 0.10 1.24 0.98
164 INT11100 Positive_regulation of Gene_expression of NPR1 2 0.37 1.49 0.98
165 INT154468 Negative_regulation of Transcription of ESR1 3 0.29 1.14 0.96
166 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95
167 INT173747 Regulation of Positive_regulation of Esr1 4 0.37 4.85 0.95
168 INT139549 Positive_regulation of Mc1r 2 0.17 0.7 0.94
169 INT236576 Positive_regulation of Binding of Esr1 3 0.41 2.39 0.92
170 INT154465 Negative_regulation of Transcription of Esr1 1 0.05 0 0.92
171 INT128755 Protein_catabolism of Esr1 10 0.57 4.61 0.9
172 INT161295 Phosphorylation of Nr3c2 1 0.07 0.09 0.9
173 INT353715 Negative_regulation of Gene_expression of Ghsr 1 0.35 0 0.89
174 INT11066 Negative_regulation of NPR1 5 0.27 0.89 0.88
175 INT23913 Negative_regulation of Gene_expression of Ttr 3 0.15 2.8 0.87
176 INT248304 Positive_regulation of Localization of Nr3c1 2 0.10 1.39 0.87
177 INT178633 Negative_regulation of Gene_expression of Pgr 2 0.21 0.26 0.86
178 INT36199 Regulation of SERPINA7 1 0.12 0 0.86
179 INT73914 Negative_regulation of Transcription of Esr1 3 0.39 0.75 0.84
180 INT174728 Positive_regulation of Transcription of ESR1 10 0.47 3.3 0.83
181 INT327363 Negative_regulation of Ttr 8 0.40 8.21 0.82
182 INT125092 Negative_regulation of Binding of ESR1 8 0.42 4.15 0.82
183 INT33818 Positive_regulation of Negative_regulation of Esr1 3 0.40 0.98 0.82
184 INT151943 Negative_regulation of Positive_regulation of UCN2 2 0.42 0.55 0.82
185 INT42356 Negative_regulation of Binding of Npr1 1 0.32 0.37 0.82
186 INT32513 Regulation of Localization of NPR1 3 0.36 0.84 0.81
187 INT63694 Regulation of Positive_regulation of GPER 1 0.00 0.41 0.79
188 INT158075 Positive_regulation of Esr2 1 0.28 0.5 0.77
189 INT10554 Regulation of Regulation of GPER 3 0.01 0.45 0.76
190 INT135691 Positive_regulation of Binding of Nr3c2 1 0.46 0.4 0.76
191 INT161778 Regulation of Gene_expression of Esr1 13 0.51 9.46 0.73
192 INT92082 Regulation of Binding of ESR1 5 0.45 2.41 0.73
193 INT66598 Negative_regulation of GPER 8 0.04 3.83 0.72
194 INT239494 Regulation of Localization of Esr1 4 0.19 1.15 0.72
195 INT54452 Regulation of Regulation of Npr1 1 0.03 0 0.72
196 INT147493 Phosphorylation of Pgr 1 0.69 1.4 0.72
197 INT73917 Regulation of Transcription of Esr1 4 0.25 1.5 0.7
198 INT5569 Phosphorylation of Npr1 3 0.18 0.61 0.7
199 INT295519 Localization of Ghsr 7 0.72 0.75 0.68
200 INT150831 Localization of Gper 1 0.65 0.33 0.67
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