GO:0042573

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Name retinoic acid metabolic process
Categary Process
Go Slim No
Go Link GO:0042573
Unique Molecular Interactions 29
Total Molecular Interactions 40
Total Single Events 759
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for retinoic acid metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for retinoic acid metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
2 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
3 INT59497 Adh1 Regulation of POMC 1 0.03 0 0.86
4 INT330462 Ngf Positive_regulation of Gene_expression of Adh1 1 0.01 0.57 0.31
5 INT330463 Setd1a Positive_regulation of Regulation of Adh1 1 0.00 0.09 0.23
6 INT153785 AHR Regulation of UGT1A3 1 0.69 0.07 0.14
7 INT4262 IL8 Positive_regulation of Localization of Adh1 1 0.12 0 0.09
8 INT154914 UGT1A9 Regulation of IGHD6-6 1 0.05 0 0.09
9 INT145622 Binding of PKLR and UGT1A3 1 0.01 0 0.06
10 INT145626 Binding of PKLR and UGT1A1 1 0.02 0 0.06
11 INT145624 Binding of PKLR and UGT1A9 1 0.02 0 0.06
12 INT351001 Binding of Adh7 and Ins1 1 0.00 1.62 0.05
13 INT206852 ESR1 Regulation of Gene_expression of CRABP2 1 0.08 1.52 0.04
14 INT278608 PPARA Positive_regulation of UGT1A9 1 0.25 0.29 0.03
15 INT206895 Binding of ESR1 and Aldh1a1 1 0.03 0 0
16 INT235303 Aldh1a1 Positive_regulation of Cpa1 1 0.17 0.4 0
17 INT206850 Binding of CRABP2 and ESR1 1 0.06 0 0
18 INT235304 Binding of Aldh1a1 and Cpa1 1 0.12 0.86 0
19 INT156700 Binding of Crp and UGT1A1 1 0.40 0 0
20 INT272007 Binding of Tsc2 and SCPEP1 1 0.27 0.46 0
21 INT351002 Binding of Adh7 and Mrgpre 1 0.00 3.65 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for retinoic acid metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in retinoic acid metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1261 Localization of Adh1 63 0.81 19.36 16.09
2 INT64563 Gene_expression of UGT1A1 27 0.75 3.31 13.43
3 INT21632 Positive_regulation of Adh1 32 0.70 15.67 11.65
4 INT4438 Negative_regulation of Localization of Adh1 18 0.59 6.23 6.95
5 INT21032 Gene_expression of Adh1 23 0.78 22.1 6.14
6 INT4598 Negative_regulation of Adh1 15 0.54 4.69 5.33
7 INT38087 Regulation of Adh1 15 0.61 4.56 4.83
8 INT20052 Negative_regulation of UGT1A1 12 0.58 4.51 4.29
9 INT75773 Gene_expression of UGT1A3 12 0.78 1.75 3.54
10 INT4261 Positive_regulation of Localization of Adh1 11 0.61 2.04 3.49
11 INT33717 Regulation of Localization of Adh1 15 0.54 3.3 2.91
12 INT99410 Positive_regulation of UGT1A1 10 0.45 2.2 2.07
13 INT148944 Transcription of UGT1A1 3 0.59 0.07 1.84
14 INT165981 Negative_regulation of UGT1A3 1 0.58 0.17 1.79
15 INT78889 Binding of UGT1A1 10 0.47 3.41 1.47
16 INT47507 Negative_regulation of Gene_expression of Adh1 1 0.11 0.42 1.17
17 INT99411 Positive_regulation of UGT1A9 2 0.39 0.65 0.88
18 INT70818 Negative_regulation of Adh7 2 0.16 1.04 0.79
19 INT195976 Gene_expression of Aldh1a1 26 0.75 14.23 0.6
20 INT75774 Transcription of UGT1A3 2 0.72 0.24 0.58
21 INT38755 Regulation of Aldh1a1 3 0.44 2.14 0.55
22 INT86006 Gene_expression of Aldh1a1 5 0.53 3.22 0.43
23 INT16177 Positive_regulation of UGT1A3 3 0.57 0.98 0.41
24 INT21631 Positive_regulation of Gene_expression of Adh1 4 0.70 12.56 0.39
25 INT38575 Negative_regulation of Positive_regulation of Adh1 2 0.37 0.33 0.39
26 INT153788 Regulation of UGT1A3 1 0.62 0.19 0.36
27 INT60477 Gene_expression of UGT1A9 2 0.24 0 0.34
28 INT38330 Binding of Adh1 4 0.41 3.98 0.3
29 INT38576 Transcription of Adh1 1 0.44 0.26 0.3
30 INT278672 Positive_regulation of Transcription of UGT1A1 1 0.27 0.07 0.22
31 INT344918 Regulation of Aldh1a1 1 0.43 0.69 0.2
32 INT153790 Regulation of Regulation of UGT1A3 1 0.62 0.09 0.17
33 INT153792 Negative_regulation of Transcription of UGT1A3 1 0.59 0.07 0.15
34 INT153786 Regulation of Transcription of UGT1A3 1 0.45 0.08 0.15
35 INT78892 Binding of UGT1A3 1 0.30 0 0.15
36 INT153791 Positive_regulation of Transcription of UGT1A3 1 0.50 0.08 0.15
37 INT105897 Regulation of UGT1A1 3 0.60 1.6 0.13
38 INT271573 Binding of SCPEP1 3 0.35 1.21 0.13
39 INT121346 Binding of UGT1A9 1 0.24 0 0.1
40 INT65839 Regulation of Regulation of Adh1 1 0.26 0.17 0.09
41 INT28904 Positive_regulation of Positive_regulation of Adh1 1 0.02 0.65 0.09
42 INT43696 Negative_regulation of Regulation of Adh1 1 0.25 0.35 0.08
43 INT206860 Binding of CRABP2 1 0.19 0.52 0.07
44 INT278678 Positive_regulation of Gene_expression of UGT1A1 1 0.37 0.09 0.06
45 INT81873 Positive_regulation of Aldh1a1 1 0.15 0.13 0.06
46 INT350999 Gene_expression of Adh7 1 0.02 1.64 0.05
47 INT206884 Gene_expression of CRABP2 3 0.40 3.57 0.04
48 INT298658 Positive_regulation of SCPEP1 2 0.10 0.69 0.03
49 INT351000 Binding of Adh7 1 0.01 3.4 0.03
50 INT278676 Localization of UGT1A9 1 0.29 0.28 0.03
51 INT86007 Transcription of Aldh1a1 2 0.54 1.41 0
52 INT235278 Negative_regulation of Binding of Aldh1a1 1 0.41 0.69 0
53 INT235263 Positive_regulation of Aldh1a1 1 0.49 0.44 0
54 INT235281 Localization of Aldh1a1 1 0.68 0.75 0
55 INT235279 Negative_regulation of Gene_expression of Aldh1a1 1 0.57 0.66 0
56 INT235264 Binding of Aldh1a1 1 0.36 0.69 0
57 INT300364 Protein_catabolism of SCPEP1 1 0.19 0.12 0
58 INT278664 Positive_regulation of Gene_expression of UGT1A3 1 0.31 0.71 0
59 INT235273 Regulation of Gene_expression of Aldh1a1 1 0.44 0.52 0
60 INT349463 Negative_regulation of Gene_expression of UGT1A1 1 0.22 1.05 0
61 INT235266 Positive_regulation of Transcription of Aldh1a1 1 0.49 0.92 0
62 INT322622 Localization of SCPEP1 1 0.07 0.27 0
63 INT235293 Transcription of Aldh1a1 1 0.67 0.92 0
64 INT350998 Positive_regulation of Adh7 1 0.01 1.25 0
65 INT86005 Positive_regulation of Transcription of Aldh1a1 1 0.39 0.86 0
66 INT235288 Negative_regulation of Aldh1a1 1 0.57 3.49 0
67 INT235286 Protein_catabolism of Aldh1a1 1 0.86 0.47 0
68 INT321667 Gene_expression of SCPEP1 1 0.04 0.46 0
69 INT235267 Positive_regulation of Gene_expression of Aldh1a1 1 0.67 3.95 0
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