GO:0042593

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Name glucose homeostasis
Categary Process
Go Slim No
Go Link GO:0042593
Unique Molecular Interactions 2043
Total Molecular Interactions 2762
Total Single Events 23948
Pain Genes Associated 108

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for glucose homeostasis. They are ordered first by their pain relevance and then by number of times they were reported for glucose homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
3 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
4 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
5 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
6 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
7 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
8 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
9 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
10 INT123451 Binding of YY1 and Adra2a 1 0.37 0 2.98
11 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
12 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
13 INT25708 Oprl1 Positive_regulation of Adra2a 1 0.25 0.15 2.63
14 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
15 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
16 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
17 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
18 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
19 INT18786 Binding of Adra2a and Nisch 2 0.19 0 1.7
20 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
21 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
22 INT24689 Binding of PLAT and Serpine1 1 0.00 3.77 1.64
23 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
24 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
25 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
26 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
27 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
28 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
29 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
30 INT63407 Binding of Oprl1 and Pck1 1 0.40 0 1.29
31 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
32 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
33 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
34 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
35 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
36 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
37 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
38 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
39 INT31549 Binding of Dbh and Vip 1 0.32 0 1.08
40 INT329962 Binding of C5 and HEPACAM 1 0.03 2.25 1.06
41 INT41175 Adra2a Regulation of Th 1 0.59 0 1.04
42 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
43 INT118859 GNA14 Positive_regulation of STAT3 1 0.01 0.38 1.03
44 INT33142 Pck1 Positive_regulation of Npr1 4 0.01 0.5 1.02
45 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
46 INT63543 Binding of Adra2a and Serpini1 1 0.13 0 1
47 INT31548 Binding of Th and Dbh 1 0.35 0 0.98
48 INT40424 CCK Regulation of Localization of INS 1 0.02 0 0.97
49 INT137919 Binding of Oprm1 and Stat3 1 0.30 0 0.97
50 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
51 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
52 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
53 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
54 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
55 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
56 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
57 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
58 INT28921 Adra2a Positive_regulation of Localization of Prl 1 0.24 0 0.9
59 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
60 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
61 INT43796 Binding of CDS1 and Adra2a 1 0.06 0 0.86
62 INT305406 Binding of CAV3 and ST8SIA2 1 0.16 0 0.86
63 INT104126 STAT3 Regulation of Phospho1 1 0.00 0.06 0.86
64 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
65 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
66 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
67 INT131463 NTRK1 Regulation of Localization of INS 1 0.41 0.63 0.8
68 INT245350 Abat Regulation of Dbh 1 0.00 0.37 0.8
69 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
70 INT56499 Neurod1 Positive_regulation of Maoa 1 0.47 0 0.8
71 INT114068 Agtr2 Regulation of Gene_expression of Insr 1 0.15 0.95 0.79
72 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
73 INT63544 Adra2a Regulation of Nisch 1 0.18 0 0.79
74 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
75 INT184116 Il10 Positive_regulation of Stat3 2 0.18 1.15 0.77
76 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
77 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
78 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
79 INT118854 GNA14 Positive_regulation of Positive_regulation of STAT3 1 0.02 0.31 0.76
80 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
81 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
82 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
83 INT348174 Binding of STAT3 and IL23R 1 0.40 1.9 0.76
84 INT155096 Stat3 Regulation of Mapk3 1 0.36 0.45 0.76
85 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
86 INT139893 Binding of Alb and Alms1 1 0.04 0.48 0.75
87 INT111194 Binding of NEUROD1 and Pck1 1 0.39 0 0.75
88 INT108611 Adra2a Regulation of Gene_expression of Nos1 1 0.10 0 0.75
89 INT84283 Binding of Adra2a and Htr1f 1 0.16 0.15 0.74
90 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74
91 INT75937 MLXIPL Regulation of Csf2 1 0.01 0.68 0.74
92 INT41165 Gtf3a Regulation of INS 1 0.00 0.15 0.74
93 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
94 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
95 INT41164 Binding of INS and SST 1 0.07 0.14 0.73
96 INT31643 POMC Regulation of INS 1 0.59 0.62 0.73
97 INT290544 Negative_regulation of Crh Positive_regulation of Insr 1 0.01 0.3 0.72
98 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
99 INT210144 Binding of Slc6a3 and Slc37a4 1 0.11 0.23 0.72
100 INT123077 Cacna1c Negative_regulation of Gene_expression of Dbi 1 0.05 0.71 0.7
101 INT20688 Adra2a Regulation of Localization of Gh1 1 0.26 0.37 0.7
102 INT81968 Binding of PLEK and Adra2a 1 0.07 0.1 0.7
103 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69
104 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
105 INT326586 SLC18A2 Negative_regulation of DDC 1 0.28 0.91 0.66
106 INT335456 Binding of PDX1 and hb 1 0.02 2.59 0.66
107 INT28975 Ins1 Positive_regulation of Positive_regulation of Dbh 1 0.21 0 0.66
108 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
109 INT132152 Adra2a Regulation of Localization of Abat 1 0.03 0 0.66
110 INT153921 Positive_regulation of Adra2a Regulation of Ednrb 1 0.01 0 0.66
111 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
112 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
113 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65
114 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
115 INT290545 Crh Positive_regulation of Positive_regulation of Insr 1 0.02 0.06 0.64
116 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64
117 INT339794 Sstr2 Positive_regulation of Gene_expression of Sstr5 1 0.08 0.25 0.64
118 INT290540 Positive_regulation of Crh Positive_regulation of Insr 1 0.02 0.06 0.64
119 INT154263 NEUROD1 Positive_regulation of Gene_expression of GAL 1 0.50 0.06 0.63
120 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
121 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
122 INT139079 Tnip1 Negative_regulation of Ptch1 1 0.20 0.63 0.62
123 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
124 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
125 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
126 INT17187 Binding of Adra2a and Fabp6 1 0.16 0.69 0.61
127 INT17186 Positive_regulation of Binding of Adra2a and Fabp6 1 0.21 0.69 0.61
128 INT257717 Binding of Bdnf and Vgf 1 0.25 0.86 0.61
129 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
130 INT177979 Binding of STAT3 and FOXI2 1 0.00 1.83 0.61
131 INT284089 Binding of NTRK2 and SERPINE1 1 0.27 0.73 0.61
132 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
133 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
134 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6
135 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
136 INT108018 Binding of Slc37a4 and Clec4d 1 0.00 1.18 0.6
137 INT83424 Binding of CD40LG and ADIPOQ 2 0.13 1 0.59
138 INT83426 ADIPOQ Negative_regulation of Binding of CD40LG 2 0.21 1 0.59
139 INT29847 INS Regulation of Localization of AVP 1 0.23 0.24 0.59
140 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
141 INT321300 Ins1 Negative_regulation of Pck1 1 0.09 0.52 0.59
142 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
143 INT321285 Ins1 Negative_regulation of G6pc 1 0.07 0.52 0.59
144 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
145 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
146 INT350699 Binding of Casp8 and Stat3 1 0.04 1.81 0.58
147 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
148 INT103165 NGF Positive_regulation of Localization of INS 1 0.05 0 0.58
149 INT257715 Bdnf Positive_regulation of Transcription of Vgf 1 0.35 0.66 0.57
150 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
151 INT185809 Binding of PDX1 and SPP1 1 0.02 1.69 0.57
152 INT303654 Binding of SST and SSTR5 1 0.22 0.46 0.57
153 INT257713 Ngf Positive_regulation of Transcription of Vgf 1 0.41 0.66 0.57
154 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56
155 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
156 INT41250 Binding of Adra2a and Eef1a1 1 0.06 0.4 0.56
157 INT145726 Binding of Abcb1a and Alms1 1 0.32 0.48 0.56
158 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
159 INT192971 Positive_regulation of Il6 Positive_regulation of Localization of Stat3 1 0.03 0.86 0.56
160 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
161 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
162 INT29252 Regulation of INS Positive_regulation of GH1 1 0.26 0.08 0.54
163 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
164 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
165 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
166 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
167 INT29253 INS Positive_regulation of GH1 1 0.44 0.08 0.53
168 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
169 INT119745 NEUROD1 Regulation of Gene_expression of BHLHE22 1 0.11 0.26 0.53
170 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
171 INT139750 Ubqln1 Regulation of Dbh 1 0.00 0 0.52
172 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52
173 INT57621 Nmb Regulation of LH 1 0.31 1.13 0.52
174 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52
175 INT139751 Dbh Regulation of Localization of Prl 1 0.02 0 0.52
176 INT114070 Agtr2 Positive_regulation of Gene_expression of Insr 1 0.13 0.34 0.52
177 INT95042 Binding of NEUROD1 and Olr1246 1 0.02 0.23 0.51
178 INT121822 Binding of STAT3 and Olr1583 1 0.00 0.21 0.51
179 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
180 INT5856 Bad Positive_regulation of Gene_expression of Penk 1 0.02 0.37 0.5
181 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
182 INT302820 Stat3 Regulation of Positive_regulation of Il7 1 0.04 1.03 0.49
183 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49
184 INT257720 Bdnf Regulation of Vgf 1 0.19 0.64 0.49
185 INT7851 Man2a2 Positive_regulation of Adra2a 1 0.13 0 0.49
186 INT302823 Stat3 Regulation of Gene_expression of Il7 1 0.04 1.03 0.49
187 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48
188 INT146113 Binding of Adra2a and Lrp1 1 0.01 1.07 0.48
189 INT257719 Ngf Regulation of Vgf 1 0.22 0.64 0.48
190 INT168110 Binding of Cnr1 and Dbh 1 0.04 0.64 0.47
191 INT189151 MTNR1B Positive_regulation of Gene_expression of IL6 1 0.01 0.35 0.47
192 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
193 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
194 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
195 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
196 INT101001 GHRH Regulation of Localization of INS 1 0.28 0 0.47
197 INT168111 Dbh Positive_regulation of Cnr1 1 0.05 0.64 0.47
198 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
199 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
200 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47

Single Events

The table below shows the top 100 pain related interactions that have been reported for glucose homeostasis. They are ordered first by their pain relevance and then by number of times they were reported in glucose homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT812 Localization of INS 1026 0.81 515.6 145.31
2 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
3 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
4 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
5 INT251 Regulation of INS 398 0.62 232.47 55.04
6 INT12717 Binding of Pck1 85 0.47 12.49 54.81
7 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
8 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
9 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
10 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
11 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
12 INT7059 Regulation of Adra2a 89 0.62 18.24 48.43
13 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
14 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
15 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
16 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
17 INT7608 Positive_regulation of Adra2a 66 0.70 17.81 35.15
18 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
19 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
20 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
21 INT8691 Localization of Insr 85 0.80 9.27 30.32
22 INT5300 Regulation of Insr 54 0.60 11.33 29.26
23 INT1166 Negative_regulation of Dbh 56 0.59 12.54 28.26
24 INT7779 Negative_regulation of Adra2a 47 0.58 9.45 28
25 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97
26 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
27 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32
28 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
29 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
30 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
31 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
32 INT8248 Binding of Adra2a 43 0.48 6.72 22.17
33 INT3382 Positive_regulation of Dbh 33 0.70 11.64 21.67
34 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
35 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85
36 INT3030 Gene_expression of Adra2a 37 0.68 5.58 19.76
37 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
38 INT2960 Regulation of Dbh 32 0.47 10.32 18.94
39 INT14114 Binding of Adra2a 30 0.48 4.24 18.53
40 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97
41 INT107454 Positive_regulation of Stat3 43 0.68 19.63 17.69
42 INT12875 Regulation of Adra2a 26 0.45 7.51 17.35
43 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93
44 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
45 INT4073 Localization of Dbh 28 0.81 6.06 16.37
46 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95
47 INT5674 Gene_expression of Adra2a 34 0.77 6.14 15.13
48 INT129584 Positive_regulation of Stat3 97 0.68 87.07 14.86
49 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8
50 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
51 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
52 INT36177 Binding of Alms1 70 0.31 35.47 13.81
53 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68
54 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
55 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
56 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4
57 INT14572 Binding of INS 205 0.48 175.43 13.38
58 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
59 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
60 INT107875 Phosphorylation of Stat3 49 0.80 13.18 12.66
61 INT35801 Regulation of Alms1 34 0.38 20.88 12.38
62 INT107033 Gene_expression of Slc37a4 66 0.62 27.34 12.35
63 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23
64 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18
65 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
66 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
67 INT79685 Positive_regulation of Gene_expression of Pparg 17 0.70 14.63 11.03
68 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
69 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
70 INT48131 Gene_expression of Slc2a4 32 0.78 14.64 10.16
71 INT12455 Negative_regulation of Adra2a 30 0.54 5.63 10.14
72 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9
73 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
74 INT114874 Gene_expression of Stat3 78 0.76 53.99 9.49
75 INT149138 Binding of PDX1 27 0.37 32.62 9.33
76 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
77 INT67612 Binding of PPARG 38 0.48 22.67 8.94
78 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89
79 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
80 INT7663 Positive_regulation of Pck1 15 0.67 3.05 8.63
81 INT82709 Negative_regulation of Slc37a4 17 0.34 3.41 8.6
82 INT168096 Transcription of Cav3 1 0.72 7.23 8.58
83 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42
84 INT114873 Phosphorylation of Stat3 63 0.82 30.19 8.23
85 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1
86 INT5401 Gene_expression of DBH 17 0.78 1.92 8.01
87 INT47546 Binding of Dbh 11 0.44 5.69 7.84
88 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
89 INT99430 Positive_regulation of Gene_expression of Slc2a4 18 0.66 10.45 7.79
90 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72
91 INT29142 Positive_regulation of Binding of Pck1 10 0.67 1.48 7.6
92 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53
93 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
94 INT103399 Positive_regulation of Positive_regulation of Pparg 11 0.66 7 7.36
95 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
96 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24
97 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
98 INT10478 Protein_catabolism of Alms1 25 0.47 12.95 7.19
99 INT6576 Localization of Adra2a 11 0.71 1.49 7.18
100 INT64370 Gene_expression of Neurod1 22 0.75 5.19 7.1
101 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
102 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
103 INT21138 Binding of ADRA2A 16 0.48 5.57 6.8
104 INT13385 Gene_expression of Bad 60 0.76 41.86 6.52
105 INT50328 Positive_regulation of Vgf 8 0.70 13.98 6.37
106 INT129918 Positive_regulation of Phosphorylation of Stat3 17 0.63 5.42 6.28
107 INT6097 Negative_regulation of NEUROD1 30 0.57 9.71 6.24
108 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
109 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
110 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
111 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
112 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
113 INT67609 Binding of Pparg 17 0.46 9.53 6.06
114 INT25193 Negative_regulation of Pck1 20 0.57 5.66 6.05
115 INT6098 Binding of NEUROD1 17 0.47 3.4 5.99
116 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94
117 INT100078 Positive_regulation of Positive_regulation of PPARG 11 0.70 3.6 5.86
118 INT86799 Gene_expression of Pck1 20 0.65 6.22 5.8
119 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
120 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61
121 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
122 INT133638 Gene_expression of Dbh 9 0.78 1.23 5.46
123 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
124 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
125 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
126 INT114058 Negative_regulation of Gene_expression of Insr 13 0.31 9.23 4.97
127 INT13650 Positive_regulation of Gene_expression of Adra2a 6 0.50 0.69 4.94
128 INT15920 Regulation of Serpine1 34 0.42 17.36 4.89
129 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
130 INT51392 Negative_regulation of Insr 18 0.27 14.75 4.84
131 INT7716 Positive_regulation of Positive_regulation of Adra2a 9 0.68 0.8 4.69
132 INT134657 Localization of Akt1 37 0.68 11.58 4.62
133 INT96504 Negative_regulation of SLC18A2 5 0.36 2.07 4.62
134 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
135 INT114871 Positive_regulation of Phosphorylation of Stat3 20 0.69 12.34 4.6
136 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
137 INT11354 Regulation of Gene_expression of SERPINE1 11 0.61 8.66 4.42
138 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4
139 INT79692 Negative_regulation of PPARG 24 0.59 16 4.31
140 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26
141 INT11634 Regulation of SERPINE1 24 0.62 20.06 4.26
142 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
143 INT51084 Binding of Insr 13 0.30 4.25 4.23
144 INT75136 Binding of Akt1 27 0.27 8.81 4.15
145 INT33229 Gene_expression of Bad 9 0.70 6.95 4.15
146 INT83035 Binding of INSR 16 0.47 9.29 4.11
147 INT91371 Negative_regulation of STAT3 34 0.59 25 4.08
148 INT97392 Gene_expression of Stat3 27 0.65 14.21 4.06
149 INT51654 Regulation of Bad 21 0.40 12.18 4.06
150 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
151 INT72936 Gene_expression of Pparg 39 0.77 19.01 4.02
152 INT112070 Negative_regulation of Gene_expression of Pparg 6 0.59 3.72 3.96
153 INT17548 Negative_regulation of Serpine1 30 0.57 24.69 3.93
154 INT6507 Binding of C5 23 0.48 15.35 3.91
155 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9
156 INT32553 Regulation of Pfkm 7 0.62 0.64 3.89
157 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
158 INT34441 Negative_regulation of Binding of Pck1 6 0.42 0.76 3.8
159 INT108761 Localization of Alms1 24 0.70 13.92 3.74
160 INT69904 Binding of Hc 11 0.35 7.79 3.69
161 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
162 INT121818 Binding of STAT3 25 0.47 11.16 3.67
163 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
164 INT136692 Localization of Akt1 12 0.78 2.14 3.65
165 INT107074 Gene_expression of C5 14 0.75 9.87 3.64
166 INT135963 Negative_regulation of Hc 19 0.42 12.36 3.63
167 INT16608 Positive_regulation of FFAR1 40 0.37 18.48 3.59
168 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58
169 INT78845 Binding of Pparg 16 0.44 11.67 3.53
170 INT20011 Regulation of NEUROD1 10 0.44 3.83 3.53
171 INT257727 Transcription of Vgf 1 0.72 7.38 3.52
172 INT10116 Localization of INSR 11 0.57 5.43 3.48
173 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
174 INT207570 Phosphorylation of IRS1 45 0.71 33.27 3.42
175 INT5400 Positive_regulation of DBH 6 0.70 2.02 3.38
176 INT133214 Regulation of PDX1 9 0.34 10.26 3.36
177 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
178 INT50326 Gene_expression of Vgf 11 0.78 4.41 3.2
179 INT12843 Regulation of Pck1 13 0.60 3.46 3.18
180 INT15253 Binding of DBH 7 0.36 3.21 3.17
181 INT64748 Regulation of Binding of Pck1 4 0.44 0.45 3.15
182 INT124736 Positive_regulation of Gene_expression of Insr 6 0.31 7.55 3.12
183 INT110956 Negative_regulation of Positive_regulation of Pparg 5 0.41 3.68 3.11
184 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
185 INT112071 Regulation of Gene_expression of Pparg 4 0.62 4.62 3.09
186 INT158630 Positive_regulation of Positive_regulation of Stat3 16 0.49 14.75 3.08
187 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
188 INT11202 Positive_regulation of Pfkm 8 0.57 1.74 3.06
189 INT46291 Negative_regulation of Dbh 6 0.56 0.91 3.06
190 INT17389 Negative_regulation of Positive_regulation of Adra2a 6 0.58 0.99 3.06
191 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
192 INT97393 Localization of Stat3 11 0.75 7.33 3.01
193 INT99187 Negative_regulation of Positive_regulation of PPARG 5 0.42 5.07 2.99
194 INT3437 Negative_regulation of Bad 5 0.48 1.66 2.99
195 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91
196 INT114878 Positive_regulation of Gene_expression of Stat3 15 0.49 10.81 2.91
197 INT32623 Negative_regulation of Regulation of INS 16 0.43 10.96 2.9
198 INT7931 Positive_regulation of Protein_catabolism of Adra2a 1 0.70 0 2.9
199 INT31923 Positive_regulation of Positive_regulation of Adra2a 7 0.44 1.88 2.89
200 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
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