GO:0042632

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Name cholesterol homeostasis
Categary Process
Go Slim No
Go Link GO:0042632
Unique Molecular Interactions 954
Total Molecular Interactions 1288
Total Single Events 9504
Pain Genes Associated 82

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cholesterol homeostasis. They are ordered first by their pain relevance and then by number of times they were reported for cholesterol homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
2 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
3 INT262165 Nr0b2 Negative_regulation of Nr5a2 1 0.02 0.5 0.92
4 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
5 INT305406 Binding of CAV3 and ST8SIA2 1 0.16 0 0.86
6 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
7 INT117604 AKR1C1 Negative_regulation of Positive_regulation of Mpo 1 0.00 1.45 0.78
8 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
9 INT139893 Binding of Alb and Alms1 1 0.04 0.48 0.75
10 INT210144 Binding of Slc6a3 and Slc37a4 1 0.11 0.23 0.72
11 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 0.00 0 0.7
12 INT98951 Positive_regulation of Binding of NR5A2 and SP3 1 0.00 0 0.7
13 INT98957 Binding of NR5A2 and SP3 1 0.00 0 0.7
14 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
15 INT98958 Binding of NR5A2 and SP1 1 0.00 0 0.7
16 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67
17 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64
18 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
19 INT66766 Casp1 Positive_regulation of Transcription of Pla2g10 1 0.06 0.19 0.6
20 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
21 INT66768 Il1b Positive_regulation of Transcription of Pla2g10 1 0.05 0.22 0.6
22 INT108018 Binding of Slc37a4 and Clec4d 1 0.00 1.18 0.6
23 INT321285 Ins1 Negative_regulation of G6pc 1 0.07 0.52 0.59
24 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
25 INT145726 Binding of Abcb1a and Alms1 1 0.32 0.48 0.56
26 INT278688 MTX1 Negative_regulation of Positive_regulation of SOAT1 1 0.04 0.69 0.54
27 INT18115 Binding of NPC1 and Oprd1 1 0.11 0 0.54
28 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
29 INT66769 Negative_regulation of Il1b Positive_regulation of Pla2g10 1 0.04 0.25 0.53
30 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
31 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
32 INT206960 Lipg Regulation of Tnf 1 0.02 0.85 0.51
33 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
34 INT206961 Lipg Regulation of Ptger2 1 0.01 0.85 0.51
35 INT206958 Lipg Regulation of Gene_expression of Ptger2 1 0.01 0.85 0.51
36 INT334901 LDLR Positive_regulation of Crp 1 0.00 1.48 0.51
37 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
38 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
39 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
40 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
41 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49
42 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
43 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
44 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
45 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
46 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
47 INT136749 COX5A Positive_regulation of Gene_expression of SCARB1 1 0.52 0.36 0.45
48 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
49 INT262155 Nr5a2 Positive_regulation of Cyp7a1 1 0.07 0.24 0.45
50 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
51 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43
52 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43
53 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
54 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
55 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
56 INT262186 Nr0b2 Positive_regulation of Negative_regulation of Cyp7a1 1 0.12 0.28 0.4
57 INT324802 Binding of Cd24a and Siglecg 1 0.03 1.34 0.4
58 INT234608 Socs3 Negative_regulation of SOAT1 1 0.01 0.54 0.39
59 INT321301 Fig4 Negative_regulation of G6pc 1 0.07 0.33 0.39
60 INT237369 SOAT1 Negative_regulation of Phosphorylation of JAK1 1 0.00 0 0.38
61 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
62 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36
63 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
64 INT28006 NPC1 Negative_regulation of Positive_regulation of Rps6ka1 1 0.01 0.37 0.33
65 INT253147 Positive_regulation of Nr1h2 Negative_regulation of Positive_regulation of Ptpn1 1 0.17 0.61 0.33
66 INT253142 Positive_regulation of Nr1h2 Negative_regulation of Gene_expression of Mmp9 1 0.05 0.6 0.33
67 INT28005 NPC1 Negative_regulation of Rps6ka1 1 0.01 0.45 0.32
68 INT206208 MRO Negative_regulation of CD24 1 0.02 1.87 0.32
69 INT122049 Binding of HSD11B1 and Lcat 1 0.21 0.83 0.31
70 INT122168 AKR1C1 Regulation of PPARG 1 0.12 0.25 0.31
71 INT235872 Phosphorylation of Ppp2ca Positive_regulation of Slc37a4 1 0.00 0.15 0.31
72 INT235886 Ppp2ca Positive_regulation of Slc37a4 1 0.00 0.15 0.3
73 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
74 INT239344 Nr1h2 Positive_regulation of Gene_expression of Srebf1 1 0.26 0.84 0.29
75 INT239324 Nr1h2 Positive_regulation of Hltf 1 0.04 0.78 0.29
76 INT239347 Nr1h2 Positive_regulation of Srebf1 1 0.26 0.78 0.29
77 INT297335 Binding of Apoc3 and Hdl1 1 0.00 0.92 0.29
78 INT298501 Paf Regulation of Negative_regulation of Alms1 1 0.00 0.63 0.29
79 INT239329 Nr1h2 Positive_regulation of Gene_expression of Hltf 1 0.04 0.84 0.29
80 INT239336 Nr1h2 Positive_regulation of Gene_expression of Fas 1 0.07 0.84 0.29
81 INT303949 LEPR Positive_regulation of SOAT1 1 0.01 0.22 0.28
82 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
83 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
84 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
85 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
86 INT213029 Positive_regulation of Binding of Apoa1 and Scarb1 1 0.09 3.38 0.27
87 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26
88 INT139357 Nr1h2 Regulation of Gene_expression of Ptges 1 0.07 0.5 0.25
89 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
90 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
91 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
92 INT78296 Negative_regulation of Binding of Ptpra and Ldlr 1 0.22 0.25 0.24
93 INT186191 Binding of SCARB1 and TBP 1 0.03 2.57 0.24
94 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
95 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
96 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
97 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
98 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
99 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
100 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
101 INT78291 Binding of Ptpra and Ldlr 1 0.20 0.25 0.24
102 INT335015 Fgf15 Negative_regulation of Gene_expression of Cyp7a1 1 0.57 0.2 0.24
103 INT262211 Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23
104 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23
105 INT262159 Positive_regulation of Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23
106 INT305798 Binding of APOA1 and OxP-11D 1 0.02 0.45 0.23
107 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
108 INT283857 APOA5 Positive_regulation of Positive_regulation of MAPK1 1 0.00 0.6 0.22
109 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
110 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22
111 INT303606 Binding of IL18 and SOAT1 1 0.05 0.52 0.22
112 INT234724 Binding of NPC1 and Cxcl1 1 0.00 0.33 0.21
113 INT282852 Binding of Slc37a4 and Slc5a8 1 0.01 0.77 0.21
114 INT282851 Binding of Slc37a4 and Sema6a 1 0.00 0.55 0.21
115 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
116 INT283860 APOA5 Negative_regulation of MAPK1 1 0.00 0.59 0.21
117 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21
118 INT277072 Binding of PLA2G7 and Lipg 1 0.00 1.32 0.21
119 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2
120 INT321286 Ins1 Negative_regulation of Transcription of G6pc 1 0.05 0.19 0.2
121 INT324824 Positive_regulation of Binding of Cd24a and Siglecg 1 0.03 0.68 0.2
122 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
123 INT64964 Binding of Alb and Cd24 1 0.02 0.2 0.2
124 INT90772 Binding of AKR1C4 and AKR1C1 1 0.39 0.08 0.2
125 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19
126 INT324822 Binding of Cd24a and Hsp90aa1 1 0.10 0.71 0.19
127 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
128 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18
129 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
130 INT308518 HSP90B1 Positive_regulation of Positive_regulation of SOAT1 1 0.00 0.65 0.18
131 INT268279 Positive_regulation of Binding of Aggf1 and Alms1 1 0.02 0.15 0.18
132 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
133 INT47344 CPZ Negative_regulation of LCAT 1 0.29 0 0.18
134 INT268280 Binding of Aggf1 and Alms1 1 0.01 0.15 0.18
135 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
136 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
137 INT231244 Binding of Fus and Alms1 1 0.20 0.57 0.17
138 INT220520 Ugt1a6b Positive_regulation of Gene_expression of Cav1 1 0.01 0.81 0.17
139 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17
140 INT146552 Kcnab3 Positive_regulation of Nr5a2 1 0.07 0 0.17
141 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
142 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17
143 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
144 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
145 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
146 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17
147 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
148 INT207350 TBXA2R Regulation of Gene_expression of ABCA1 1 0.10 0 0.17
149 INT190635 Binding of Lmo2 and Nr1h2 1 0.09 0.59 0.16
150 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16
151 INT229289 FGF19 Negative_regulation of CYP7A1 1 0.26 0.32 0.16
152 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
153 INT43510 Apoa2 Positive_regulation of Localization of POMC 1 0.03 0 0.16
154 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
155 INT297345 Apoe Negative_regulation of Csf2 1 0.17 0.66 0.16
156 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
157 INT206212 UTS2R Positive_regulation of CD24 1 0.09 0.71 0.15
158 INT86216 Hpd Regulation of NPC1 1 0.02 0.93 0.15
159 INT186380 Binding of SOAT1 and Stat6 1 0.02 0.11 0.15
160 INT329850 APOA5 Negative_regulation of Transcription of APOC3 1 0.24 0.85 0.15
161 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15
162 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
163 INT123180 Bmp6 Positive_regulation of Lamtor1 1 0.01 0.61 0.14
164 INT338449 Nps Regulation of Alms1 1 0.04 0.13 0.14
165 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14
166 INT207360 PTGDS Negative_regulation of Negative_regulation of ABCA1 1 0.25 0 0.14
167 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14
168 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14
169 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
170 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14
171 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14
172 INT332256 Pdgfa Positive_regulation of SOAT1 1 0.01 0.51 0.14
173 INT207353 ZNF398 Regulation of ABCA1 1 0.00 0 0.14
174 INT239355 Binding of Nr1h2 and Positive_regulation of Gene_expression of CETP 1 0.17 3.75 0.14
175 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
176 INT206209 MRO Negative_regulation of Transcription of CD24 1 0.02 0.76 0.14
177 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14
178 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14
179 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
180 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13
181 INT308534 Binding of HIVEP1 and Alms1 1 0.00 0.96 0.13
182 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13
183 INT241910 Binding of Alb and Alms1 1 0.02 0.52 0.13
184 INT262618 Binding of SOAT1 and Kras 1 0.00 0.81 0.12
185 INT155388 Binding of LPA and Lipg 1 0.00 1.22 0.12
186 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12
187 INT270723 Negative_regulation of HMGCR Positive_regulation of LDLR 1 0.02 0.52 0.12
188 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
189 INT173121 PPARA Negative_regulation of Gene_expression of CYP7A1 1 0.18 0.48 0.12
190 INT175196 Binding of NCOR1 and NUP62 1 0.02 0.84 0.12
191 INT33752 Apoa2 Regulation of Localization of POMC 1 0.06 0 0.12
192 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12
193 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
194 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12
195 INT33750 Apoa2 Regulation of Agt 1 0.07 0 0.12
196 INT100478 Binding of Camk1d and Alms1 1 0.17 0 0.12
197 INT33751 Apoa2 Positive_regulation of Positive_regulation of POMC 1 0.09 0 0.11
198 INT2458 Apoa2 Positive_regulation of Localization of Avp 1 0.10 0 0.11
199 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11
200 INT213042 Apoa1 Positive_regulation of Nos3 1 0.10 2.17 0.11

Single Events

The table below shows the top 100 pain related interactions that have been reported for cholesterol homeostasis. They are ordered first by their pain relevance and then by number of times they were reported in cholesterol homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
2 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93
3 INT36177 Binding of Alms1 70 0.31 35.47 13.81
4 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68
5 INT35801 Regulation of Alms1 34 0.38 20.88 12.38
6 INT107033 Gene_expression of Slc37a4 66 0.62 27.34 12.35
7 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
8 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
9 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
10 INT82709 Negative_regulation of Slc37a4 17 0.34 3.41 8.6
11 INT168096 Transcription of Cav3 1 0.72 7.23 8.58
12 INT39457 Positive_regulation of SOAT1 32 0.67 22.8 8.28
13 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1
14 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87
15 INT47994 Negative_regulation of Lipg 45 0.50 27.19 7.24
16 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21
17 INT10478 Protein_catabolism of Alms1 25 0.47 12.95 7.19
18 INT197493 Localization of Apoe 61 0.79 27.48 7.06
19 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05
20 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
21 INT19146 Negative_regulation of Apoa2 19 0.36 5.34 6.73
22 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
23 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
24 INT63042 Binding of Apoe 59 0.48 31.23 5.88
25 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
26 INT186063 Phosphorylation of SOAT1 29 0.28 11.77 5.34
27 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04
28 INT3476 Phosphorylation of Npc1 7 0.48 0 4.84
29 INT66760 Gene_expression of Pla2g10 8 0.76 4.43 4.83
30 INT136754 Gene_expression of SCARB1 64 0.77 43.28 4.82
31 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
32 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
33 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
34 INT49652 Gene_expression of Fabp4 7 0.67 6.23 4.61
35 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56
36 INT66762 Negative_regulation of Pla2g10 6 0.48 7.8 4.54
37 INT10923 Positive_regulation of Lipg 30 0.50 22.87 4.26
38 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08
39 INT156416 Gene_expression of Lipg 38 0.67 18.35 4.07
40 INT76227 Binding of NPC1 30 0.41 32.31 4.05
41 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
42 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
43 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
44 INT176208 Gene_expression of Nr1h2 27 0.59 22.75 3.84
45 INT351271 Binding of Fabp4 1 0.48 3.92 3.79
46 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
47 INT108761 Localization of Alms1 24 0.70 13.92 3.74
48 INT18515 Gene_expression of Lipg 18 0.66 9.3 3.72
49 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
50 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
51 INT91929 Gene_expression of Nr5a2 5 0.31 2.15 3.52
52 INT40368 Positive_regulation of LRP5 5 0.49 3.19 3.51
53 INT57728 Regulation of LDLR 25 0.41 13.18 3.46
54 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
55 INT111482 Gene_expression of Cd24a 23 0.72 13.74 3.37
56 INT191807 Gene_expression of CD24 75 0.78 53.92 3.34
57 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32
58 INT5166 Binding of Ldlr 14 0.48 11.95 3.32
59 INT72141 Binding of Apoe 11 0.37 10.91 3.27
60 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
61 INT97710 Localization of Apoe 1 0.79 7.18 3.2
62 INT17562 Negative_regulation of Lipg 32 0.51 16.91 3.17
63 INT179489 Positive_regulation of Fabp4 3 0.60 3.62 3.15
64 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13
65 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05
66 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04
67 INT10830 Regulation of Apoa1 11 0.44 15.1 3.04
68 INT12237 Positive_regulation of Lipg 19 0.60 11.09 2.92
69 INT10556 Regulation of Apoa2 5 0.44 0.51 2.8
70 INT59342 Negative_regulation of NPC1 20 0.44 20.21 2.79
71 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73
72 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
73 INT49759 Negative_regulation of CETP 43 0.58 52 2.68
74 INT50080 Binding of APOE 38 0.45 29.61 2.67
75 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64
76 INT118251 Localization of Pla2g10 5 0.73 3.07 2.55
77 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
78 INT169553 Positive_regulation of Slc37a4 9 0.13 2.94 2.49
79 INT144274 Gene_expression of Cav3 28 0.78 3.21 2.47
80 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
81 INT176205 Gene_expression of Cyp7a1 8 0.69 2.5 2.45
82 INT3475 Regulation of Phosphorylation of Npc1 3 0.36 0 2.45
83 INT181880 Positive_regulation of Apoa1 19 0.66 21.19 2.43
84 INT231557 Positive_regulation of Phosphorylation of SOAT1 7 0.22 5.22 2.33
85 INT2452 Localization of Apoa2 9 0.55 0 2.3
86 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
87 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
88 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
89 INT168959 Gene_expression of CAV3 5 0.65 0.7 2.2
90 INT22843 Localization of Lipg 5 0.33 1.95 2.12
91 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
92 INT86460 Binding of Slc37a4 5 0.04 1.8 2.08
93 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
94 INT49313 Positive_regulation of Gene_expression of Apoa1 3 0.68 9.55 2.01
95 INT4691 Regulation of Lipg 10 0.61 4.7 1.99
96 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
97 INT173512 Positive_regulation of Gene_expression of Alms1 12 0.44 8.66 1.95
98 INT190883 Gene_expression of Apoc3 16 0.38 14.18 1.93
99 INT118250 Positive_regulation of Gene_expression of Pla2g10 3 0.49 2.47 1.93
100 INT78960 Binding of SOAT1 9 0.36 2.56 1.92
101 INT176173 Positive_regulation of Nr1h2 19 0.52 10.95 1.88
102 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
103 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86
104 INT351269 Localization of Fabp4 1 0.74 1.9 1.85
105 INT169862 Regulation of NPC1 13 0.53 13.61 1.84
106 INT39458 Negative_regulation of SOAT1 8 0.57 10.56 1.83
107 INT21813 Gene_expression of Apoa2 10 0.61 3.68 1.81
108 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
109 INT136752 Positive_regulation of Gene_expression of SCARB1 5 0.69 10.63 1.76
110 INT26513 Regulation of Fabp4 3 0.45 0.72 1.76
111 INT118946 Binding of FABP4 4 0.44 3.97 1.71
112 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
113 INT168964 Negative_regulation of Gene_expression of CAV3 1 0.47 0 1.68
114 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67
115 INT156484 Binding of Apoa1 4 0.47 6.78 1.63
116 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
117 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
118 INT262117 Negative_regulation of Gene_expression of Cyp7a1 3 0.25 0.91 1.6
119 INT42585 Positive_regulation of Phosphorylation of Npc1 3 0.19 0 1.59
120 INT9466 Binding of APOB 27 0.41 19.36 1.56
121 INT39459 Gene_expression of SOAT1 10 0.75 7.62 1.52
122 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
123 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
124 INT181881 Positive_regulation of Gene_expression of Apoa1 13 0.48 14.31 1.45
125 INT18114 Gene_expression of NPC1 45 0.66 57.85 1.44
126 INT206244 Binding of CD24 7 0.48 5.71 1.43
127 INT100540 Localization of SOAT1 9 0.78 2.67 1.42
128 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
129 INT155845 Transcription of SOAT1 6 0.67 2.89 1.4
130 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
131 INT181882 Localization of Apoa1 8 0.71 7.94 1.37
132 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36
133 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
134 INT10829 Regulation of Ldlr 12 0.34 8.12 1.35
135 INT351270 Phosphorylation of Fabp4 1 0.62 1.31 1.31
136 INT307261 Negative_regulation of FABP4 4 0.46 1.3 1.3
137 INT32796 Negative_regulation of G6pc 7 0.36 2.44 1.27
138 INT139356 Regulation of Nr1h2 2 0.43 2.95 1.27
139 INT20238 Regulation of APOB 9 0.61 11.52 1.26
140 INT141862 Binding of Cav1 11 0.36 1.32 1.25
141 INT191804 Transcription of CD24 10 0.72 12.43 1.25
142 INT86446 Protein_catabolism of Lipg 9 0.50 3.52 1.25
143 INT76925 Negative_regulation of G6pc 6 0.57 2.9 1.25
144 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
145 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
146 INT32797 Regulation of G6pc 2 0.28 1.63 1.23
147 INT122171 Negative_regulation of AKR1C1 5 0.59 1.92 1.22
148 INT168095 Positive_regulation of Transcription of Cav3 1 0.47 0.91 1.2
149 INT66759 Transcription of Pla2g10 1 0.59 0.41 1.19
150 INT60291 Regulation of SOAT1 9 0.19 3.99 1.17
151 INT23199 Binding of LDLR 22 0.47 17.08 1.16
152 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
153 INT82703 Transcription of LDLR 6 0.64 0.4 1.13
154 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11
155 INT321337 Transcription of G6pc 1 0.32 1.21 1.09
156 INT176183 Gene_expression of Abcg5 1 0.77 5.01 1.08
157 INT118947 Positive_regulation of FABP4 6 0.67 3.44 1.07
158 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
159 INT168957 Positive_regulation of CAV3 1 0.40 0 1.06
160 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
161 INT168960 Binding of CAV3 1 0.30 0 1.05
162 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
163 INT142914 Negative_regulation of Localization of Lipg 1 0.14 0.49 1.04
164 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
165 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
166 INT235929 Regulation of Positive_regulation of Alms1 2 0.02 2.84 1.02
167 INT44874 Regulation of LCAT 1 0.62 0.15 1
168 INT52113 Gene_expression of CETP 25 0.69 25.71 0.99
169 INT1267 Regulation of G6PC 3 0.44 1.39 0.98
170 INT82707 Positive_regulation of Transcription of LDLR 1 0.62 0.34 0.98
171 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97
172 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
173 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
174 INT82702 Positive_regulation of Positive_regulation of LDLR 4 0.45 1.08 0.95
175 INT211557 Gene_expression of Scarb1 30 0.75 5.03 0.94
176 INT106952 Positive_regulation of NPC1 23 0.43 22.9 0.94
177 INT334977 Regulation of Gene_expression of Cyp7a1 2 0.40 0.43 0.94
178 INT149903 Localization of Cav3 3 0.80 1.1 0.93
179 INT205902 Regulation of Gene_expression of Slc37a4 1 0.09 0.4 0.93
180 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
181 INT173514 Negative_regulation of Gene_expression of Alms1 3 0.06 3.49 0.91
182 INT321336 Negative_regulation of Transcription of G6pc 1 0.20 1.04 0.91
183 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9
184 INT294479 Gene_expression of Scarb1 1 0.02 3.08 0.9
185 INT180451 Positive_regulation of Apoa2 15 0.67 12.65 0.89
186 INT72672 Positive_regulation of Gene_expression of APOA1 4 0.67 3.81 0.89
187 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88
188 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
189 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85
190 INT197772 Positive_regulation of Pla2g10 1 0.38 5.94 0.85
191 INT181885 Binding of Apoa1 7 0.35 5.66 0.84
192 INT10828 Regulation of Apob 7 0.39 7.55 0.83
193 INT150108 Positive_regulation of Gene_expression of Slc37a4 5 0.35 2.09 0.83
194 INT190089 Binding of Abca1 5 0.36 2.21 0.83
195 INT79941 Negative_regulation of Npc1 9 0.59 3.97 0.82
196 INT149905 Negative_regulation of Cav3 2 0.43 0.98 0.82
197 INT72334 Negative_regulation of LRP5 7 0.35 1.71 0.81
198 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
199 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
200 INT340843 Binding of Cd24a 1 0.02 0.24 0.8
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