GO:0042640

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Name anagen
Categary Process
Go Slim No
Go Link GO:0042640
Unique Molecular Interactions 722
Total Molecular Interactions 987
Total Single Events 9080
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for anagen. They are ordered first by their pain relevance and then by number of times they were reported for anagen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
2 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
3 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
4 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
5 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
6 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
7 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
8 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
9 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
10 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
11 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
12 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
13 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
14 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
15 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
16 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
17 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
18 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
19 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
20 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
21 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
22 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
23 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
24 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
25 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
26 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
27 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
28 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
29 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
30 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
31 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
32 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
33 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91
34 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9
35 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
36 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87
37 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86
38 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84
39 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
40 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
41 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
42 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79
43 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
44 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
45 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
46 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
47 INT335592 Ltp Positive_regulation of Positive_regulation of Akt1 1 0.01 0.19 0.74
48 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
49 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
50 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71
51 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
52 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
53 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
54 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
55 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
56 INT153797 NUBPL Negative_regulation of PPARD 1 0.02 0.69 0.64
57 INT134047 Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
58 INT134044 Positive_regulation of Fitm1 Positive_regulation of Phosphorylation of Akt1 1 0.05 0.21 0.63
59 INT71942 Negative_regulation of PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.62
60 INT101320 Negative_regulation of Ptgs1 Positive_regulation of Ptgs2 1 0.03 0.2 0.62
61 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61
62 INT71944 PTGS2 Negative_regulation of VN1R106P 1 0.00 0.07 0.61
63 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61
64 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
65 INT137247 Slc6a14 Negative_regulation of Ptgs2 2 0.19 1.38 0.58
66 INT137248 Slc6a14 Negative_regulation of Gene_expression of Ptgs2 1 0.19 1.32 0.58
67 INT125546 Arsa Negative_regulation of Gene_expression of PTGS2 1 0.00 0.53 0.58
68 INT87294 SERPINA3 Negative_regulation of PTGS2 1 0.25 0.6 0.58
69 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58
70 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
71 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56
72 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
73 INT114064 Agtr2 Positive_regulation of Phosphorylation of Akt1 1 0.24 0.41 0.54
74 INT71943 Regulation of ZNF697 Negative_regulation of PTGS2 1 0.01 0.07 0.54
75 INT129912 Skiv2l Negative_regulation of Gene_expression of PTGS2 1 0.00 0.87 0.54
76 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54
77 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54
78 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
79 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54
80 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
81 INT71945 ZNF697 Negative_regulation of PTGS2 1 0.01 0.07 0.53
82 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53
83 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
84 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52
85 INT69882 Ptger2 Positive_regulation of Gene_expression of Ptgs2 1 0.19 0.6 0.52
86 INT116541 Binding of Ptgs2 and ZNF398 1 0.00 0.68 0.52
87 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
88 INT102844 Pdc Regulation of Akt1 1 0.03 0 0.49
89 INT150205 Tnrc6a Negative_regulation of PTGS2 1 0.00 0.42 0.49
90 INT135584 CSF2 Regulation of PTGS2 1 0.06 1.28 0.49
91 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
92 INT150788 ZNF398 Regulation of PTGS2 1 0.02 0.5 0.48
93 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48
94 INT62164 Il1b Positive_regulation of PTGS2 1 0.00 0.49 0.47
95 INT62163 Il1b Positive_regulation of Positive_regulation of PTGS2 1 0.00 0.49 0.47
96 INT145434 Binding of HMOX1 and PTGS2 1 0.02 0.41 0.47
97 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
98 INT309126 Edc4 Positive_regulation of Akt1 1 0.02 0.99 0.47
99 INT145436 Binding of HMOX2 and PTGS2 1 0.02 0.41 0.47
100 INT309144 Dlat Positive_regulation of Akt1 1 0.03 0.99 0.47
101 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
102 INT127662 Negative_regulation of PDE4A Negative_regulation of Gene_expression of PTGS2 1 0.15 0.75 0.47
103 INT114065 Akt1 Regulation of Gene_expression of Insr 1 0.13 0.28 0.46
104 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
105 INT335594 Myo5a Regulation of Hmmr 1 0.00 0.39 0.45
106 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
107 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
108 INT139900 Kcne2 Positive_regulation of Akt1 1 0.06 2.95 0.44
109 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
110 INT322396 Hist1h1t Positive_regulation of Akt1 1 0.01 0 0.42
111 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
112 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41
113 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
114 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
115 INT231842 Pcdh8 Positive_regulation of Akt1 1 0.00 1.59 0.4
116 INT322409 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of Akt1 1 0.04 0 0.4
117 INT166155 Ccr9 Positive_regulation of Akt1 1 0.58 2.14 0.39
118 INT106505 Binding of Ptgds and Ptgs2 1 0.01 0.93 0.39
119 INT200096 Negative_regulation of Il1a Negative_regulation of Gene_expression of Ptgs2 1 0.00 1.45 0.39
120 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37
121 INT157171 Binding of PTGS2 and Pla2g1b 1 0.02 0.26 0.37
122 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
123 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
124 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
125 INT278766 HOXA9 Positive_regulation of Gene_expression of PTGS2 1 0.43 1.28 0.35
126 INT278749 NUP98 Positive_regulation of Gene_expression of PTGS2 1 0.46 1.28 0.35
127 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
128 INT89501 Il6 Positive_regulation of Ptgs2 1 0.01 1.07 0.35
129 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35
130 INT309118 Dlat Positive_regulation of Positive_regulation of Akt1 1 0.03 0.32 0.34
131 INT89505 Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
132 INT249019 Gabrg1 Positive_regulation of Akt1 1 0.02 0 0.34
133 INT134303 Cpox Negative_regulation of PTGS2 1 0.00 0.77 0.34
134 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
135 INT89502 Positive_regulation of Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
136 INT214377 Akt1 Regulation of Amph 1 0.15 0 0.33
137 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
138 INT52700 Prkcg Positive_regulation of Ptgs2 1 0.12 0.3 0.32
139 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
140 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
141 INT108879 Negative_regulation of PTGS2 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.43 0.31
142 INT303063 Akt1 Negative_regulation of Gene_expression of Syn1 1 0.09 0.45 0.31
143 INT64859 Negative_regulation of PTGS1 Negative_regulation of PTGS2 1 0.07 0.05 0.31
144 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
145 INT116594 Negative_regulation of PTGS2 Negative_regulation of Gene_expression of IL6 1 0.22 0.45 0.31
146 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
147 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3
148 INT139044 AKR1B1 Regulation of Gene_expression of PTGS2 1 0.09 0.37 0.3
149 INT156084 Binding of PTGS2 and AKR1C3 1 0.02 0.31 0.3
150 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 0.37 3.89 0.29
151 INT62207 Binding of PTGS1 and PTGS2 3 0.06 0.07 0.29
152 INT265467 HRAS Negative_regulation of Gene_expression of PTGS2 1 0.01 0.84 0.29
153 INT132367 Lgals1 Positive_regulation of Akt1 1 0.22 0.13 0.28
154 INT317533 Akt1 Positive_regulation of Nos1 1 0.43 0 0.28
155 INT243214 Myst2 Negative_regulation of Gene_expression of Ptgs2 1 0.01 1.4 0.28
156 INT159201 Binding of Ppard and Ppara 1 0.01 0.68 0.28
157 INT91751 Binding of PTGS2 and Hmox1 1 0.00 0.21 0.27
158 INT149322 Amph Positive_regulation of Akt1 1 0.39 0 0.27
159 INT142447 PTGS2 Regulation of Gene_expression of PTGIS 1 0.30 0.24 0.27
160 INT107392 PTGS2 Positive_regulation of PTGS1 2 0.31 1.01 0.26
161 INT114069 Negative_regulation of Agtr2 Positive_regulation of Ptgs2 1 0.08 0.49 0.26
162 INT69120 MOCS1 Regulation of PTGS2 1 0.00 0.39 0.26
163 INT96402 Binding of PTGS2 and TBXAS1 1 0.02 0.32 0.26
164 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26
165 INT64860 PTGS1 Negative_regulation of PTGS2 1 0.07 0 0.26
166 INT96401 Binding of PTGER1 and PTGS2 1 0.00 0.32 0.26
167 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26
168 INT303082 Akt1 Negative_regulation of Gene_expression of Mafk 1 0.20 0.37 0.26
169 INT308661 Akt1 Positive_regulation of Chuk 1 0.02 0.6 0.25
170 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
171 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25
172 INT314047 THL Negative_regulation of Phosphorylation of Akt1 1 0.14 0.71 0.25
173 INT102625 IL6 Regulation of Gene_expression of PTGS2 1 0.11 0.29 0.24
174 INT326094 Akt1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.49 0.24
175 INT136798 Spp1 Regulation of Gene_expression of PTGS2 1 0.08 0.65 0.24
176 INT326092 Gene_expression of Akt1 Negative_regulation of Gopc 1 0.03 0.55 0.24
177 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24
178 INT166663 Mpzl2 Negative_regulation of Positive_regulation of Ptgs2 1 0.29 0.3 0.24
179 INT102617 PTAFR Regulation of Gene_expression of PTGS2 1 0.12 0.29 0.24
180 INT326093 Akt1 Positive_regulation of Gopc 1 0.03 0.43 0.23
181 INT132382 Nos2 Positive_regulation of PTGS2 1 0.02 0.1 0.23
182 INT272143 PTAFR Positive_regulation of Gene_expression of PTGS2 1 0.12 1.59 0.23
183 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23
184 INT145014 Positive_regulation of GAST Positive_regulation of PTGS2 1 0.31 0.51 0.22
185 INT323173 THRA Positive_regulation of Phosphorylation of Akt1 1 0.00 0 0.22
186 INT133164 Ptgs2 Regulation of Tnf 1 0.14 0.98 0.22
187 INT260844 NRP2 Positive_regulation of Akt1 1 0.00 0.73 0.22
188 INT145012 GAST Positive_regulation of PTGS2 1 0.42 0.51 0.22
189 INT112134 Gast Positive_regulation of Gene_expression of Ptgs2 1 0.28 0.19 0.21
190 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
191 INT69318 ST3GAL4 Positive_regulation of Gene_expression of PTGS2 1 0.35 0.09 0.21
192 INT323174 DBT Positive_regulation of Phosphorylation of Akt1 1 0.01 0 0.21
193 INT112136 Egf Positive_regulation of Gene_expression of Ptgs2 1 0.21 0.19 0.21
194 INT116468 VEGFA Positive_regulation of Akt1 1 0.04 1.39 0.21
195 INT289356 Binding of Akt1 and Fgf2 1 0.03 0.82 0.21
196 INT309661 C5 Positive_regulation of Phosphorylation of Akt1 1 0.51 0.45 0.21
197 INT221237 Prkca Regulation of Phosphorylation of Akt1 1 0.01 0.28 0.2
198 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
199 INT297544 Pou3f3 Regulation of Notch1 1 0.06 0.41 0.2
200 INT283747 Tbs1 Positive_regulation of Ptgs2 1 0.00 0 0.2

Single Events

The table below shows the top 100 pain related interactions that have been reported for anagen. They are ordered first by their pain relevance and then by number of times they were reported in anagen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
2 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
3 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
4 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
5 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
6 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
7 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
8 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
9 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
10 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
11 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
12 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46
13 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
14 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
15 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
16 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85
17 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
18 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
19 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
20 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
21 INT17848 Binding of PTGS2 70 0.46 32.1 20.6
22 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
23 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44
24 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
25 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39
26 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
27 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39
28 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
29 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39
30 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
31 INT75137 Regulation of Akt1 74 0.48 37.89 9.7
32 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53
33 INT120967 Negative_regulation of Phosphorylation of Akt1 47 0.57 23.67 8.98
34 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69
35 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
36 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83
37 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
38 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39
39 INT126748 Positive_regulation of Positive_regulation of Akt1 26 0.55 11.15 7.08
40 INT90097 Localization of PTGS2 15 0.69 6.14 6.63
41 INT61114 Gene_expression of Ppard 23 0.75 14.98 6.62
42 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52
43 INT67656 Positive_regulation of Positive_regulation of PTGS2 12 0.46 4.83 6.17
44 INT117721 Positive_regulation of Gene_expression of Akt1 22 0.69 6.26 6.08
45 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06
46 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02
47 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
48 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86
49 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
50 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71
51 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
52 INT114993 Binding of Myo5a 15 0.30 11.46 5.48
53 INT134657 Localization of Akt1 37 0.68 11.58 4.62
54 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5
55 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44
56 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
57 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
58 INT75136 Binding of Akt1 27 0.27 8.81 4.15
59 INT52616 Negative_regulation of Positive_regulation of PTGS2 13 0.43 4.95 4.13
60 INT138872 Gene_expression of SPINK5 21 0.58 30.11 4.12
61 INT139898 Negative_regulation of Positive_regulation of Akt1 15 0.42 4.66 4.06
62 INT115773 Negative_regulation of Localization of Ptgs2 6 0.43 2.99 3.81
63 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
64 INT132223 Negative_regulation of Negative_regulation of Akt1 6 0.42 2.75 3.66
65 INT136692 Localization of Akt1 12 0.78 2.14 3.65
66 INT84891 Gene_expression of PPARD 10 0.78 6.8 3.64
67 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
68 INT53200 Binding of Ptgs2 11 0.48 5.08 3.54
69 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27
70 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
71 INT102034 Positive_regulation of Ppard 10 0.69 3.97 3.17
72 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16
73 INT52694 Negative_regulation of Positive_regulation of Ptgs2 9 0.43 4.72 3.11
74 INT84890 Negative_regulation of PPARD 7 0.59 3.27 3.1
75 INT117720 Negative_regulation of Gene_expression of Akt1 11 0.37 2.33 3.08
76 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
77 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
78 INT112758 Binding of Ppard 7 0.37 3.6 2.87
79 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
80 INT117715 Regulation of Phosphorylation of Akt1 15 0.51 3.23 2.78
81 INT68505 Positive_regulation of Negative_regulation of PTGS2 8 0.49 2.26 2.76
82 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
83 INT214355 Binding of Akt1 13 0.36 3.72 2.59
84 INT127176 Transcription of Ptgs2 8 0.58 4.68 2.58
85 INT17846 Binding of Ptgs2 8 0.32 4.66 2.48
86 INT102033 Negative_regulation of Ppard 5 0.37 4.14 2.48
87 INT163544 Binding of Psen1 40 0.36 15.28 2.42
88 INT78958 Regulation of Negative_regulation of Ptgs2 6 0.42 2.61 2.3
89 INT138286 Regulation of Positive_regulation of Akt1 13 0.45 4.93 2.22
90 INT101516 Positive_regulation of PPARD 8 0.49 4.75 2.19
91 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
92 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
93 INT60723 Localization of Psen2 5 0.68 2.11 2.02
94 INT97579 Negative_regulation of Localization of PTGS2 2 0.08 2.37 1.99
95 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
96 INT77805 Regulation of Gene_expression of Ptgs2 6 0.51 2.7 1.92
97 INT52691 Positive_regulation of Transcription of Ptgs2 5 0.44 3 1.9
98 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
99 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
100 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
101 INT142236 Regulation of Phosphorylation of Akt1 13 0.61 5.02 1.75
102 INT165332 Negative_regulation of Negative_regulation of Akt1 5 0.42 3.27 1.7
103 INT117714 Regulation of Positive_regulation of Akt1 3 0.61 0.44 1.61
104 INT95056 Positive_regulation of Gene_expression of Ppard 5 0.52 3.84 1.6
105 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
106 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
107 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
108 INT84889 Positive_regulation of Gene_expression of PPARD 4 0.70 2.94 1.49
109 INT149622 Positive_regulation of Transcription of Ptgs2 3 0.28 2.48 1.46
110 INT84888 Binding of PPARD 5 0.48 2.82 1.45
111 INT78646 Regulation of Psen2 4 0.20 1.78 1.42
112 INT190768 Regulation of Positive_regulation of Ptgs2 1 0.04 1.2 1.41
113 INT86823 Regulation of Transcription of PTGS2 3 0.19 1.48 1.4
114 INT311241 Transcription of Myo5a 1 0.50 1.61 1.37
115 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
116 INT135658 Phosphorylation of Ptgs2 2 0.23 1.39 1.34
117 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
118 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
119 INT132495 Negative_regulation of Gene_expression of Ppard 4 0.44 2.64 1.28
120 INT101026 Positive_regulation of Negative_regulation of Ptgs2 2 0.35 1.01 1.23
121 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
122 INT179372 Positive_regulation of Localization of PTGS2 2 0.38 0.35 1.21
123 INT110780 Localization of Notch1 2 0.06 0.47 1.19
124 INT59078 Positive_regulation of Transcription of PTGS2 5 0.69 2.36 1.17
125 INT219879 Positive_regulation of SPINK5 4 0.30 7.64 1.16
126 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
127 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
128 INT62981 Protein_catabolism of PTGS2 5 0.78 1.09 1.11
129 INT207203 Transcription of Akt1 6 0.67 3.73 1.1
130 INT64862 Negative_regulation of Negative_regulation of PTGS2 3 0.36 0.76 1.09
131 INT70505 Positive_regulation of Positive_regulation of Ptgs2 4 0.49 2.22 1.08
132 INT83647 Negative_regulation of Negative_regulation of Ptgs2 1 0.28 1.97 1.05
133 INT191050 Positive_regulation of Negative_regulation of Akt1 6 0.31 1.82 1.03
134 INT64177 Negative_regulation of Transcription of PTGS2 4 0.41 1.99 1.03
135 INT78645 Negative_regulation of Gene_expression of Psen2 1 0.14 0.13 1.01
136 INT112759 Negative_regulation of Binding of Ppard 2 0.39 2.08 0.99
137 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94
138 INT6833 Binding of Notch1 4 0.36 0.05 0.94
139 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
140 INT192785 Regulation of Myo5a 4 0.05 9.05 0.93
141 INT68265 Positive_regulation of Negative_regulation of Ptgs2 3 0.46 0.08 0.92
142 INT163508 Regulation of Gene_expression of Akt1 3 0.45 1.65 0.92
143 INT149624 Regulation of Transcription of Ptgs2 1 0.16 0.84 0.84
144 INT84892 Negative_regulation of Gene_expression of PPARD 2 0.43 1.85 0.83
145 INT78647 Positive_regulation of Localization of Psen2 1 0.16 0.14 0.83
146 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
147 INT115770 Negative_regulation of Positive_regulation of Ptgs2 4 0.43 0.94 0.79
148 INT120057 Regulation of Localization of PTGS2 1 0.28 0.14 0.78
149 INT57958 Positive_regulation of Myo5a 9 0.41 7.52 0.77
150 INT94756 Positive_regulation of PSEN2 8 0.49 4.59 0.77
151 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
152 INT193849 Positive_regulation of Gene_expression of Psen2 5 0.44 4.92 0.76
153 INT71950 Positive_regulation of Binding of PTGS2 2 0.31 0.31 0.74
154 INT78649 Binding of Psen2 7 0.36 5.9 0.73
155 INT151170 Regulation of Regulation of Akt1 2 0.45 3.28 0.73
156 INT78648 Regulation of Binding of Psen2 1 0.14 0.2 0.73
157 INT78957 Regulation of Transcription of Ptgs2 1 0.17 0.49 0.72
158 INT82544 Regulation of Positive_regulation of PTGS2 4 0.39 1.41 0.71
159 INT127175 Negative_regulation of Transcription of Ptgs2 3 0.47 2.11 0.7
160 INT152437 Localization of SPINK5 4 0.54 3.97 0.69
161 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
162 INT207204 Regulation of Transcription of Akt1 3 0.35 1.41 0.66
163 INT92341 Localization of Ptgs2 5 0.75 2.04 0.64
164 INT91765 Positive_regulation of Gene_expression of PSEN2 8 0.49 4.57 0.63
165 INT281466 Negative_regulation of Regulation of Akt1 1 0.33 0.31 0.63
166 INT6831 Negative_regulation of Binding of Notch1 1 0.27 0 0.6
167 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
168 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
169 INT115772 Positive_regulation of Localization of Ptgs2 1 0.46 0.5 0.55
170 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
171 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
172 INT115771 Positive_regulation of Positive_regulation of Ptgs2 1 0.46 0.5 0.54
173 INT218900 Regulation of Negative_regulation of Akt1 3 0.15 1.73 0.53
174 INT303669 Regulation of SPINK5 1 0.24 0.65 0.53
175 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
176 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
177 INT142835 Regulation of Localization of Ptgs2 2 0.25 0.26 0.5
178 INT276189 Regulation of Localization of Akt1 1 0.43 0.2 0.5
179 INT101515 Negative_regulation of Positive_regulation of PPARD 2 0.35 0.68 0.47
180 INT84893 Negative_regulation of Binding of PPARD 1 0.43 0.5 0.46
181 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
182 INT316041 Transcription of Psen2 1 0.64 1.1 0.45
183 INT132946 Negative_regulation of Positive_regulation of Ppard 1 0.42 0.09 0.44
184 INT234249 Regulation of PSEN1 6 0.37 2.21 0.43
185 INT94036 Negative_regulation of Transcription of Ptgs2 1 0.30 0.52 0.43
186 INT234257 Regulation of Gene_expression of PSEN1 6 0.44 1.98 0.42
187 INT193856 Localization of Psen1 19 0.73 9.79 0.41
188 INT36396 Positive_regulation of Psen2 6 0.44 4.57 0.39
189 INT158764 Binding of SPINK5 7 0.35 8.84 0.37
190 INT195574 Localization of Myo5a 4 0.34 1.1 0.36
191 INT177773 Localization of PSEN1 4 0.73 0.89 0.36
192 INT82545 Positive_regulation of Regulation of PTGS2 1 0.19 0.15 0.35
193 INT261682 Positive_regulation of Positive_regulation of PSEN2 1 0.21 0.55 0.33
194 INT321348 Positive_regulation of Localization of Akt1 1 0.30 0.08 0.32
195 INT258685 Regulation of Gene_expression of Notch1 2 0.40 1.45 0.3
196 INT144419 Regulation of Ppard 1 0.24 0.91 0.3
197 INT224298 Negative_regulation of PSEN2 6 0.57 2.29 0.28
198 INT61115 Localization of Ppard 2 0.66 1.99 0.28
199 INT159198 Positive_regulation of Binding of Ppard 1 0.34 0.68 0.28
200 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27
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