GO:0042641

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Name actomyosin
Categary Component
Go Slim No
Go Link GO:0042641
Unique Molecular Interactions 44
Total Molecular Interactions 63
Total Single Events 330
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for actomyosin. They are ordered first by their pain relevance and then by number of times they were reported for actomyosin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296460 Binding of Gria2 and Myo18a 1 0.01 1.49 1.06
2 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
3 INT255287 Binding of Stx1a and Vti1b 1 0.35 0 0.58
4 INT296475 Binding of Pick1 and Myo18a 2 0.01 1.63 0.57
5 INT335594 Myo5a Regulation of Hmmr 1 0.00 0.39 0.45
6 INT296444 Binding of Rbm39 and Myo18a 1 0.00 0.56 0.36
7 INT255285 Binding of Snap25 and Stx1a 1 0.07 0 0.33
8 INT296482 Binding of GRIP1 and Myo18a 1 0.00 0.35 0.32
9 INT255291 Binding of Napb and Stx1a 1 0.21 0 0.29
10 INT290847 Regulation of Binding of Stx1a and Fig4 1 0.05 0.26 0.24
11 INT296470 Binding of Cacng2 and Myo18a 1 0.00 0.22 0.24
12 INT354723 Binding of ASIC3 and Myo18a 1 0.00 0.25 0.23
13 INT290846 Binding of Stx1a and Fig4 1 0.07 0.26 0.22
14 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
15 INT354703 Binding of ASIC1 and Myo18a 1 0.00 1.11 0.17
16 INT191355 HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
17 INT191354 Negative_regulation of HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
18 INT347638 Negative_regulation of Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
19 INT347639 Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
20 INT138195 Binding of HDAC4 and Creb1 1 0.03 0.17 0.13
21 INT354718 Binding of INADL and Myo18a 1 0.00 0.13 0.12
22 INT142002 Trav9n-1 Negative_regulation of CDC42BPA 1 0.00 0 0.09
23 INT141997 HEY1 Negative_regulation of CDC42BPA 1 0.00 0 0.08
24 INT57965 Myo5a Negative_regulation of Cyp2e1 1 0.01 0.09 0.07
25 INT249421 Binding of Stx1a and Vamp2 1 0.10 0 0.04
26 INT249414 Binding of Stx1a and Dcaf12l2 1 0.00 0 0.04
27 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03
28 INT249417 Binding of Stx1a and Napa 1 0.13 0 0
29 INT249426 Mbp Positive_regulation of Stx1a 1 0.10 0.11 0
30 INT200647 HDAC4 Positive_regulation of CASP9 1 0.10 0.93 0
31 INT240420 Myo5a Positive_regulation of CD4 1 0.06 0.27 0
32 INT239080 Binding of PPY and KAT2B 1 0.02 2.38 0
33 INT281321 STX1A Positive_regulation of Gene_expression of tf 1 0.07 0.96 0
34 INT249408 Mbp Positive_regulation of Localization of Stx1a 1 0.11 0.33 0
35 INT249405 Binding of Mbp and Stx1a 1 0.11 0 0
36 INT354708 Negative_regulation of Binding of ASIC1 and Myo18a 1 0.00 0.13 0
37 INT249420 Stx1a Positive_regulation of Binding of Snap25 1 0.13 0 0
38 INT249410 Vamp2 Regulation of Binding of Stx1a 1 0.06 0 0
39 INT277610 Binding of Runx2 and Hdac4 1 0.32 0.78 0
40 INT200650 HDAC4 Regulation of Gene_expression of AKT1 1 0.16 0.66 0
41 INT200644 HDAC4 Positive_regulation of CASP8 1 0.07 0.92 0
42 INT277611 Binding of Mef2c and Hdac4 1 0.34 1.12 0
43 INT131787 Binding of Myo5a and Pon1 1 0.02 0.06 0
44 INT225587 Binding of Kat2b and Cytip 1 0.12 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for actomyosin. They are ordered first by their pain relevance and then by number of times they were reported in actomyosin. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT114993 Binding of Myo5a 15 0.30 11.46 5.48
2 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42
3 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16
4 INT277591 Gene_expression of Hdac4 22 0.77 7.77 1.79
5 INT171816 Gene_expression of Stx1a 5 0.20 1.67 1.65
6 INT54996 Regulation of KAT2B 1 0.19 0.38 1.45
7 INT311241 Transcription of Myo5a 1 0.50 1.61 1.37
8 INT277581 Positive_regulation of Hdac4 4 0.50 1.47 1.25
9 INT234473 Gene_expression of HDAC4 8 0.18 6.28 0.99
10 INT192785 Regulation of Myo5a 4 0.05 9.05 0.93
11 INT201222 Positive_regulation of STX1A 1 0.45 0.51 0.93
12 INT171818 Localization of Stx1a 1 0.08 0.22 0.85
13 INT57958 Positive_regulation of Myo5a 9 0.41 7.52 0.77
14 INT213381 Gene_expression of STX1A 5 0.65 3.41 0.71
15 INT149296 Negative_regulation of CDC42BPA 1 0.01 0.91 0.55
16 INT91769 Gene_expression of CDC42BPA 2 0.02 1.71 0.5
17 INT333910 Positive_regulation of Gene_expression of HDAC4 2 0.07 1.5 0.49
18 INT179685 Positive_regulation of HDAC4 3 0.24 4.09 0.48
19 INT249396 Binding of Stx1a 9 0.15 0.23 0.42
20 INT234083 Gene_expression of Stx1a 10 0.64 1.41 0.41
21 INT277579 Binding of Hdac4 1 0.37 3.84 0.38
22 INT277604 Negative_regulation of Hdac4 4 0.51 2.89 0.36
23 INT239084 Localization of KAT2B 4 0.73 3.08 0.36
24 INT195574 Localization of Myo5a 4 0.34 1.1 0.36
25 INT277598 Regulation of Gene_expression of Hdac4 1 0.45 0.91 0.36
26 INT142001 Negative_regulation of Gene_expression of CDC42BPA 1 0.01 0.42 0.33
27 INT266973 Negative_regulation of KAT2B 1 0.01 0.99 0.29
28 INT124568 Regulation of HDAC4 5 0.24 3.03 0.27
29 INT290851 Regulation of Stx1a 1 0.09 0.26 0.24
30 INT141998 Negative_regulation of Localization of CDC42BPA 1 0.01 0.35 0.22
31 INT240411 Negative_regulation of Binding of Myo5a 1 0.09 0.97 0.21
32 INT277584 Negative_regulation of Gene_expression of Hdac4 1 0.43 0.85 0.21
33 INT142000 Localization of CDC42BPA 1 0.01 0.35 0.21
34 INT277594 Positive_regulation of Localization of Hdac4 1 0.50 1.71 0.21
35 INT64080 Positive_regulation of Stx1a 3 0.08 0 0.2
36 INT277593 Localization of Hdac4 1 0.75 2.07 0.2
37 INT277600 Positive_regulation of Gene_expression of Hdac4 1 0.60 0.48 0.2
38 INT191155 Binding of HDAC4 5 0.08 2.79 0.17
39 INT91770 Positive_regulation of Gene_expression of CDC42BPA 1 0.01 1.29 0.17
40 INT277601 Positive_regulation of Positive_regulation of Hdac4 1 0.50 0.18 0.16
41 INT64081 Regulation of Stx1a 3 0.25 0.07 0.14
42 INT330879 Gene_expression of Myo18a 2 0.02 0.51 0.14
43 INT277582 Regulation of Hdac4 1 0.45 0.36 0.14
44 INT192783 Phosphorylation of Myo5a 1 0.04 2.01 0.12
45 INT234460 Negative_regulation of Gene_expression of HDAC4 2 0.04 1.55 0.11
46 INT290852 Binding of Stx1a 1 0.13 0 0.11
47 INT334306 Positive_regulation of Stx1a 1 0.10 0.65 0.11
48 INT320951 Negative_regulation of Gene_expression of Stx1a 1 0.40 0.56 0.11
49 INT234465 Regulation of Negative_regulation of HDAC4 1 0.04 0.74 0.11
50 INT160258 Negative_regulation of Myo5a 3 0.35 3.96 0.09
51 INT101082 Positive_regulation of KAT2B 1 0.38 0.76 0.09
52 INT239085 Binding of KAT2B 1 0.18 2.04 0.09
53 INT277599 Phosphorylation of Hdac4 1 0.82 3.24 0.05
54 INT192784 Positive_regulation of Gene_expression of Myo5a 2 0.45 3.39 0.04
55 INT320948 Negative_regulation of Stx1a 1 0.41 0.41 0.04
56 INT259662 Positive_regulation of Regulation of HDAC4 1 0.03 0.77 0.03
57 INT332926 Localization of HDAC4 1 0.10 0.11 0.03
58 INT243247 Localization of Stx1a 3 0.42 0.53 0
59 INT200682 Phosphorylation of HDAC4 2 0.44 1.24 0
60 INT249387 Positive_regulation of Regulation of Stx1a 1 0.20 0.07 0
61 INT277580 Regulation of Localization of Hdac4 1 0.39 0 0
62 INT276524 Regulation of Myo18a 1 0.04 0 0
63 INT286005 Positive_regulation of Binding of Myo5a 1 0.41 0.97 0
64 INT354669 Positive_regulation of Myo18a 1 0.00 0.45 0
65 INT200668 Regulation of Phosphorylation of HDAC4 1 0.24 0.71 0
66 INT249380 Positive_regulation of Phosphorylation of Stx1a 1 0.19 0.07 0
67 INT277577 Transcription of Hdac4 1 0.69 0 0
68 INT286004 Positive_regulation of Positive_regulation of Myo5a 1 0.41 0.58 0
69 INT252138 Binding of STX1A 1 0.35 0 0
70 INT249400 Negative_regulation of Binding of Stx1a 1 0.17 0.08 0
71 INT239368 Negative_regulation of Binding of HDAC4 1 0.06 1.44 0
72 INT338233 Regulation of Gene_expression of HDAC4 1 0.03 0.18 0
73 INT249375 Phosphorylation of Stx1a 1 0.33 0.07 0
74 INT277603 Negative_regulation of Phosphorylation of Hdac4 1 0.43 0.39 0
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